IOTest CD25-APC-Alexa Fluor 700
... CD25), β (IL-2Rβ, p75, or CD122), and γ (IL2Rγ or p64). T lymphocytes express an intermediate-affinity IL-2 receptor that comprises β /γ or α/γ chain complex. IL-2Rβ and IL-2Rγ chains are involved in IL-2mediated cellular signaling (1 – 3). The CD25 molecule (known as Tac antigen and interleukine-2 ...
... CD25), β (IL-2Rβ, p75, or CD122), and γ (IL2Rγ or p64). T lymphocytes express an intermediate-affinity IL-2 receptor that comprises β /γ or α/γ chain complex. IL-2Rβ and IL-2Rγ chains are involved in IL-2mediated cellular signaling (1 – 3). The CD25 molecule (known as Tac antigen and interleukine-2 ...
Metabolic Adaptation and Protein Complexes in Prokaryotes
... higher levels of proteome organization. These larger multi-protein complex entities link successive steps in biological processes like a conveyor belt involving shared multifunctional components. This interesting finding of a factory-like arrangement of bacterial protein complexes churning out a max ...
... higher levels of proteome organization. These larger multi-protein complex entities link successive steps in biological processes like a conveyor belt involving shared multifunctional components. This interesting finding of a factory-like arrangement of bacterial protein complexes churning out a max ...
4.3. monosaccharides
... strong interactions between water molecules and the polyanionic complex. It is present in cartilage and tendon, vitreous humour (eyes), extracellular matrix, mucosal surface and synovial fluid. Chondroitin sulfate. It promotes tension resistance in cartilage, tendon and arteries. It is present in ...
... strong interactions between water molecules and the polyanionic complex. It is present in cartilage and tendon, vitreous humour (eyes), extracellular matrix, mucosal surface and synovial fluid. Chondroitin sulfate. It promotes tension resistance in cartilage, tendon and arteries. It is present in ...
Cnidarians: An evolutionarily conserved model system for
... and insects. Although little is known to date about cnidarian embryogenesis on the molecular level, new molecular data indicate that some of the homologous genes involved in bilaterian embryogenesis act during cnidarian regeneration. Therefore, the intriguing possibility exists that a common set of ...
... and insects. Although little is known to date about cnidarian embryogenesis on the molecular level, new molecular data indicate that some of the homologous genes involved in bilaterian embryogenesis act during cnidarian regeneration. Therefore, the intriguing possibility exists that a common set of ...
File - Hoblitzell`s Science Spot
... intestinal cells at an equal rate. b. larger peptide molecules must be completely broken down into amino acids to be absorbed into the bloodstream from the intestine. c. cells in the small intestine preferentially absorb different types of amino acids, which causes competition by amino acids at the ...
... intestinal cells at an equal rate. b. larger peptide molecules must be completely broken down into amino acids to be absorbed into the bloodstream from the intestine. c. cells in the small intestine preferentially absorb different types of amino acids, which causes competition by amino acids at the ...
The role of calcium and other ions in sorting and delivery in the late
... EGTA and EGTA-AM make a prima facie case that release of luminal Ca2+ is required for fusion events in the late endocytic pathway, this has been challenged. The BAPTA effects on vacuole fusion have been proposed to occur via effects on the ionic strength of the fusion assay medium, resulting in remo ...
... EGTA and EGTA-AM make a prima facie case that release of luminal Ca2+ is required for fusion events in the late endocytic pathway, this has been challenged. The BAPTA effects on vacuole fusion have been proposed to occur via effects on the ionic strength of the fusion assay medium, resulting in remo ...
Onset of lactation in the bovine mammary gland:
... spindle-associated protein 1, centromere proteins F, A, and N, topoisomerase II alpha, minichromosome maintenance proteins and homologs, core histone macro-H2A.2, microtubule-associated protein tau, kinesin-like proteins, and tubulin beta 5. In addition, among other downregulated genes, nine (10 tra ...
... spindle-associated protein 1, centromere proteins F, A, and N, topoisomerase II alpha, minichromosome maintenance proteins and homologs, core histone macro-H2A.2, microtubule-associated protein tau, kinesin-like proteins, and tubulin beta 5. In addition, among other downregulated genes, nine (10 tra ...
IN SILICO SCREENING, SYNTHESIS AND IN VITRO EVALUATION OF SOME... DERIVATIVES AS DIHYDROFOLATE REDUCTASE INHIBITORS FOR ANTICANCER ACTIVITY:
... Objective: The main objective of this research was to in silico screen, synthesize, characterize and in vitro evaluate some quinazolin-/e/one derivatives as dihydrofolate reductase (DHFR) inhibitors for anti-cancer activity. Method: The present study reports a new series of Quinazoline and quinazoli ...
... Objective: The main objective of this research was to in silico screen, synthesize, characterize and in vitro evaluate some quinazolin-/e/one derivatives as dihydrofolate reductase (DHFR) inhibitors for anti-cancer activity. Method: The present study reports a new series of Quinazoline and quinazoli ...
Combined in silico modeling and metabolomics analysis to
... ABSTRACT: The increasing demand for recombinant therapeutic proteins highlights the need to constantly improve the efficiency and yield of these biopharmaceutical products from mammalian cells, which is fully achievable only through proper understanding of cellular functioning. Towards this end, the ...
... ABSTRACT: The increasing demand for recombinant therapeutic proteins highlights the need to constantly improve the efficiency and yield of these biopharmaceutical products from mammalian cells, which is fully achievable only through proper understanding of cellular functioning. Towards this end, the ...
cellular homeostasis - Advances in Physiology Education
... encyclopedia response.). Cells, like body fluids and compartments, use the chemistry of enzymes, organic and inorganic molecules, to carry out normal function. Many cells maintain a cytoplasmic pH (pHi) of 7.0–7.3 ([H⫹] ⫽ 50–100 nanomolar). Within this narrow range of pHi, i.e., [H⫹], many cellular ...
... encyclopedia response.). Cells, like body fluids and compartments, use the chemistry of enzymes, organic and inorganic molecules, to carry out normal function. Many cells maintain a cytoplasmic pH (pHi) of 7.0–7.3 ([H⫹] ⫽ 50–100 nanomolar). Within this narrow range of pHi, i.e., [H⫹], many cellular ...
MALDI Imaging of Formalin-Fixed Paraffin
... of FFPE showed positive results on blocks stored for less than 2 days. However, most samples are stored for more than one year, and thus our objective was to establish a novel strategy using as a model system 6-hydroxydopamine (6-OHDA) treated rat brain tissues stored in FFPE blocks for more than 9 ...
... of FFPE showed positive results on blocks stored for less than 2 days. However, most samples are stored for more than one year, and thus our objective was to establish a novel strategy using as a model system 6-hydroxydopamine (6-OHDA) treated rat brain tissues stored in FFPE blocks for more than 9 ...
A Toc75-like protein import channel is abundant in chloroplasts
... and AY 040053. All peptides obtained by either Edman degradation or mass spectrometry showed sequence similarity to the EST clones (Figure 2). Both AF 360205 and AY 040053 locate to the same gene on chromosome V in Arabidopsis, at5g19620. The polypeptide deduced from the EST sequences has a length o ...
... and AY 040053. All peptides obtained by either Edman degradation or mass spectrometry showed sequence similarity to the EST clones (Figure 2). Both AF 360205 and AY 040053 locate to the same gene on chromosome V in Arabidopsis, at5g19620. The polypeptide deduced from the EST sequences has a length o ...
144803525 - BORA
... and without altering the chemical equilibrium between reactants and products. They are crucial for signal transduction and cell regulation, often via protein kinases (PK) and protein phosphatases (PP) [9]. The catalytic activity of enzymes involves the binding of their substrates in a specific inter ...
... and without altering the chemical equilibrium between reactants and products. They are crucial for signal transduction and cell regulation, often via protein kinases (PK) and protein phosphatases (PP) [9]. The catalytic activity of enzymes involves the binding of their substrates in a specific inter ...
A Toc75like protein import channel is abundant in
... and AY 040053. All peptides obtained by either Edman degradation or mass spectrometry showed sequence similarity to the EST clones (Figure 2). Both AF 360205 and AY 040053 locate to the same gene on chromosome V in Arabidopsis, at5g19620. The polypeptide deduced from the EST sequences has a length o ...
... and AY 040053. All peptides obtained by either Edman degradation or mass spectrometry showed sequence similarity to the EST clones (Figure 2). Both AF 360205 and AY 040053 locate to the same gene on chromosome V in Arabidopsis, at5g19620. The polypeptide deduced from the EST sequences has a length o ...
Structures of
... - Example: hemoglobin is a dimer of αβ protomers - Contact region between subunits resembles the interior of a single subunit protein: closely packed nonpolar residues, hydrogen bonding, interchain disulfide bridges, but generally less hydrophobic than the hydrophobic core of a single subunit prot ...
... - Example: hemoglobin is a dimer of αβ protomers - Contact region between subunits resembles the interior of a single subunit protein: closely packed nonpolar residues, hydrogen bonding, interchain disulfide bridges, but generally less hydrophobic than the hydrophobic core of a single subunit prot ...
Chapter 7 Ans
... immune response : A coordinated set of steps, including production of antibodies, that the immune system takes in response to an antigen. ...
... immune response : A coordinated set of steps, including production of antibodies, that the immune system takes in response to an antigen. ...
GeneCensus - Gerstein Lab Publications
... the enzyme in each genome. Additionally, it allows for the visualization of sequence similarity between the organisms compared with the specific enzyme for which the flux is being measured. Below the percent identity table, another table outlines the expression values of that specific enzyme in yeas ...
... the enzyme in each genome. Additionally, it allows for the visualization of sequence similarity between the organisms compared with the specific enzyme for which the flux is being measured. Below the percent identity table, another table outlines the expression values of that specific enzyme in yeas ...
red blood cell (rbc) membrane and enzyme disorders
... - Stability of the mutant enzyme (RBC lacks biosynthesis) - Possibility of compensation for the deficiency by isoenzyme overexpression or use of alternative pathways ...
... - Stability of the mutant enzyme (RBC lacks biosynthesis) - Possibility of compensation for the deficiency by isoenzyme overexpression or use of alternative pathways ...
Journal: Applied Microbiology and Biotechnology
... GLC concentrations, much lower relative LAC release rates are found (Cruz et al., 1999; Häggström et al., 1996). Renner et al. (1972) concluded that a high glycolytic flux easily saturates the synthetic and oxidative pathway and, hence, increases the glucose-specific lactate yield. Due to the high ...
... GLC concentrations, much lower relative LAC release rates are found (Cruz et al., 1999; Häggström et al., 1996). Renner et al. (1972) concluded that a high glycolytic flux easily saturates the synthetic and oxidative pathway and, hence, increases the glucose-specific lactate yield. Due to the high ...
Cloning and characterization of an eukaryotic initiation factor
... kinase assay buffer (25 mM HEPES, pH 7.4, 25 mM h-glycerophosphate, 25 mM MgCl2, 2 mM dithiothreitol, 0.1 mM sodium orthovanadate) in the presence of g-32P-ATP (3000 Ci/mmol) at 30 jC for 30 min. Proteins were separated by SDS-PAGE and visualized by autoradiography. (B) Expression of BeK wildtype (B ...
... kinase assay buffer (25 mM HEPES, pH 7.4, 25 mM h-glycerophosphate, 25 mM MgCl2, 2 mM dithiothreitol, 0.1 mM sodium orthovanadate) in the presence of g-32P-ATP (3000 Ci/mmol) at 30 jC for 30 min. Proteins were separated by SDS-PAGE and visualized by autoradiography. (B) Expression of BeK wildtype (B ...
ATP - Mhanafi123`s Blog
... Pyruvate is the end product of Glycolysis with 7 ATP as high energy phosphate. ( older textbook still counting as 8 ATP). In unaerobic Glycolysis of certain type of muscle for sprinters, lack of oxygen cause inactive respiratory chain. NADH will reduces Pyruvate, and Lactate is the final product of ...
... Pyruvate is the end product of Glycolysis with 7 ATP as high energy phosphate. ( older textbook still counting as 8 ATP). In unaerobic Glycolysis of certain type of muscle for sprinters, lack of oxygen cause inactive respiratory chain. NADH will reduces Pyruvate, and Lactate is the final product of ...
Oncogenic regulation of tumor metabolic reprogramming
... the interaction between genetic susceptibility and environmental factors in which a clear hereditary pattern is not found. This complexity causes difficulties in the risk evaluation, diagnosis and treatment of these diseases. Cancer, one of the most prevalent multifactorial diseases, is characterize ...
... the interaction between genetic susceptibility and environmental factors in which a clear hereditary pattern is not found. This complexity causes difficulties in the risk evaluation, diagnosis and treatment of these diseases. Cancer, one of the most prevalent multifactorial diseases, is characterize ...
Nucleoredoxin and Wnt signaling in F9 cells
... regulation of bone density, and osteoarthritis [15]. There are nineteen known Wnts in vertebrates that signal through three pathways: canonical Wnt/β-catenin, planar cell polarity (PCP) or Wnt/Ca2+ pathway. My research focuses on canonical Wnt signaling as my lab reported several years ago that RA a ...
... regulation of bone density, and osteoarthritis [15]. There are nineteen known Wnts in vertebrates that signal through three pathways: canonical Wnt/β-catenin, planar cell polarity (PCP) or Wnt/Ca2+ pathway. My research focuses on canonical Wnt signaling as my lab reported several years ago that RA a ...
Powerpoint
... the amounts and rates it needs them Nearly all body cells have the genes to make all proteins ...
... the amounts and rates it needs them Nearly all body cells have the genes to make all proteins ...
Protein core - Acsu.buffalo.edu
... domain of lambda repressor, and select for mutants that retain activity Assay: functional lambda repressor will make bacteria resistant to lambda phage Lim & Sauer, Nature 339, 31 (1989) ...
... domain of lambda repressor, and select for mutants that retain activity Assay: functional lambda repressor will make bacteria resistant to lambda phage Lim & Sauer, Nature 339, 31 (1989) ...
Paracrine signalling
Paracrine signaling is a form of cell-cell communication in which a cell produces a signal to induce changes in nearby cells, altering the behavior or differentiation of those cells. Signaling molecules known as paracrine factors diffuse over a relatively short distance (local action), as opposed to endocrine factors (hormones which travel considerably longer distances via the circulatory system), juxtacrine interactions, and autocrine signaling. Cells that produce paracrine factors secrete them into the immediate extracellular environment. Factors then travel to nearby cells in which the gradient of factor received determines the outcome. However, the exact distance that paracrine factors can travel is not certain.Although paracrine signaling elicits a diverse array of responses in the induced cells, most paracrine factors utilize a relatively streamlined set of receptors and pathways. In fact, different organs in the body -even between different species - are known to utilize a similar sets of paracrine factors in differential development. The highly conserved receptors and pathways can be organized into four major families based on similar structures: Fibroblast growth factor (FGF) family, Hedgehog family, Wnt family, and TGF-β superfamily. Binding of a paracrine factor to its respective receptor initiates signal transduction cascades, eliciting different responses.