
Taxonomy, biology and physiology of fungi
... The vesicles fuse with the plasma membrane at the tip, and release their contents. ...
... The vesicles fuse with the plasma membrane at the tip, and release their contents. ...
Cancer Prone Disease Section Oculocutaneous Albinism Atlas of Genetics and Cytogenetics
... NP_000363.1) composed of 529 amino acids. TYR is a melanosomal membrane bound glycoenzyme with a type-3 copper active site. The mature TYR polypeptide includes an 18-amino acid long N-terminal signal peptide, six Nglycosylation sites, two copper binding sites (CuA and CuB) and one transmembrane (TM) ...
... NP_000363.1) composed of 529 amino acids. TYR is a melanosomal membrane bound glycoenzyme with a type-3 copper active site. The mature TYR polypeptide includes an 18-amino acid long N-terminal signal peptide, six Nglycosylation sites, two copper binding sites (CuA and CuB) and one transmembrane (TM) ...
What is metabolic engineering?
... • The basic construction of such protein chips has some similarities to DNA chips, such as the use of a glass or plastic surface dotted with an array of molecules. • Known proteins are analyzed using functional assays that are on the chip. For example, chip surfaces can contain enzymes, receptor pro ...
... • The basic construction of such protein chips has some similarities to DNA chips, such as the use of a glass or plastic surface dotted with an array of molecules. • Known proteins are analyzed using functional assays that are on the chip. For example, chip surfaces can contain enzymes, receptor pro ...
Protein Structures: Experiments and Modeling
... Fold possibly correct, but errors are very likely. Fold likely correct except that some surface loops might be mismodelled. Many small errors can normally be detected. Fold normally correct and number of errors in surface loops is small. Water molecules and small ligands become visible. Many small e ...
... Fold possibly correct, but errors are very likely. Fold likely correct except that some surface loops might be mismodelled. Many small errors can normally be detected. Fold normally correct and number of errors in surface loops is small. Water molecules and small ligands become visible. Many small e ...
Protein Structures - the University of California, Davis
... Fold possibly correct, but errors are very likely. Fold likely correct except that some surface loops might be mismodelled. Many small errors can normally be detected. Fold normally correct and number of errors in surface loops is small. Water molecules and small ligands become visible. Many small e ...
... Fold possibly correct, but errors are very likely. Fold likely correct except that some surface loops might be mismodelled. Many small errors can normally be detected. Fold normally correct and number of errors in surface loops is small. Water molecules and small ligands become visible. Many small e ...
as a PDF
... Presented here is a progress report on a pilot-scale structural genomics effort to use the structures of Haemophilus influenzae hypothetical proteins to assist in the assignment of function. The experimental approach is briefly described which includes target selection, gene cloning, expression and ...
... Presented here is a progress report on a pilot-scale structural genomics effort to use the structures of Haemophilus influenzae hypothetical proteins to assist in the assignment of function. The experimental approach is briefly described which includes target selection, gene cloning, expression and ...
Symbolic Protein Data Base
... in the sequence. Note: this might be dierent from the PDB position and there might be breaks in chains. There is also a number of other residue features, like coordinates of C atoms (to which residue side chains are attached). For this work, of interest is only the secondary structure assignment, ...
... in the sequence. Note: this might be dierent from the PDB position and there might be breaks in chains. There is also a number of other residue features, like coordinates of C atoms (to which residue side chains are attached). For this work, of interest is only the secondary structure assignment, ...
Egg Protein in Sports Nutrition
... to be necessary to support optimal lean muscle growth during periods of strength training. Scientists and athletic trainers are in agreement that proteins are the building blocks of muscle and are necessary for muscle growth and repair. The presence of adequate dietary proteins during training can h ...
... to be necessary to support optimal lean muscle growth during periods of strength training. Scientists and athletic trainers are in agreement that proteins are the building blocks of muscle and are necessary for muscle growth and repair. The presence of adequate dietary proteins during training can h ...
Luciferase Reporter Vector Protocol
... factor results in the expression of luciferase, which initiates a powerful bioluminescent reaction when exposed to its substrate, luciferin. Light emitted from the chemical reaction is directly proportional to the amount of enzyme and thus the binding activity of the targeted transcription factor. C ...
... factor results in the expression of luciferase, which initiates a powerful bioluminescent reaction when exposed to its substrate, luciferin. Light emitted from the chemical reaction is directly proportional to the amount of enzyme and thus the binding activity of the targeted transcription factor. C ...
Expression profiles of Ciona tailbud embryos - Development
... Data Bank of Japan database, 502 clusters of them showed significant matches to reported proteins with distinct function, whereas 184 lacked sufficient information to be categorized (including reported proteins with undefined function) and 527 had no significant similarities to known proteins. Seque ...
... Data Bank of Japan database, 502 clusters of them showed significant matches to reported proteins with distinct function, whereas 184 lacked sufficient information to be categorized (including reported proteins with undefined function) and 527 had no significant similarities to known proteins. Seque ...
Slide 1 - Elsevier
... is indicated by an arrow labeled intron. Numbers specify amino acid number. B) depicts the location of the αhelices (H1-H12) of the VDR LBD. The α-helices are depicted as filled boxes and the region containing the βturns is drawn as a cross-hatched box. The E1 and AF-2 regions are shown below the α- ...
... is indicated by an arrow labeled intron. Numbers specify amino acid number. B) depicts the location of the αhelices (H1-H12) of the VDR LBD. The α-helices are depicted as filled boxes and the region containing the βturns is drawn as a cross-hatched box. The E1 and AF-2 regions are shown below the α- ...
Delivering of Proteins to the Plant Vacuole—An Update
... mechanism of vacuolar ontogeny in plant seeds [17]. In the GA-mediated pathway the proteins leave the ER in coat protein complex II (COPII) vesicles to the GA and from here are transported to the vacuole via the prevacuolar compartment (PVC). Studying storage proteins, additional pathways bypassing ...
... mechanism of vacuolar ontogeny in plant seeds [17]. In the GA-mediated pathway the proteins leave the ER in coat protein complex II (COPII) vesicles to the GA and from here are transported to the vacuole via the prevacuolar compartment (PVC). Studying storage proteins, additional pathways bypassing ...
Slide 1
... activation of Smad3/B-cateninmediated TGF-B1 signaling pathway and its unique biological responses in MSCs ...
... activation of Smad3/B-cateninmediated TGF-B1 signaling pathway and its unique biological responses in MSCs ...
Stomatal development - The Company of Biologists
... the myogenic and neurogenic factors. Given their similar regulatory logic, however, the stomatal bHLH transcription factors provide a powerful outgroup with which to test functions and capabilities of the bHLH transcription factors in general. Inter- and intracellular signaling Stomata are distribut ...
... the myogenic and neurogenic factors. Given their similar regulatory logic, however, the stomatal bHLH transcription factors provide a powerful outgroup with which to test functions and capabilities of the bHLH transcription factors in general. Inter- and intracellular signaling Stomata are distribut ...
PDF
... the myogenic and neurogenic factors. Given their similar regulatory logic, however, the stomatal bHLH transcription factors provide a powerful outgroup with which to test functions and capabilities of the bHLH transcription factors in general. Inter- and intracellular signaling Stomata are distribut ...
... the myogenic and neurogenic factors. Given their similar regulatory logic, however, the stomatal bHLH transcription factors provide a powerful outgroup with which to test functions and capabilities of the bHLH transcription factors in general. Inter- and intracellular signaling Stomata are distribut ...
2007 Workshop handout
... and Y are a variety of amino acids. When I’m in the Gly-Pro-Hyp configuration, I am the most thermally stable. Beauty does come at a cost as my subunit Glycine is very picky and is required at every 3rd position. It desires to be at the interior of the helix. Occasionally, terrible things happen and ...
... and Y are a variety of amino acids. When I’m in the Gly-Pro-Hyp configuration, I am the most thermally stable. Beauty does come at a cost as my subunit Glycine is very picky and is required at every 3rd position. It desires to be at the interior of the helix. Occasionally, terrible things happen and ...
Metabolic reprogramming in glioblastoma: the influence of cancer
... (ACACA) and fatty acid synthase are also upregulated in many cancers, including GB, and play a role in tumorigenesis.29,30 The first committed step of lipid biosynthesis is catalyzed by ACACA. Inhibition of ACACA disrupts cancer stem cell self-renewal and growth and as such holds promise as a novel ...
... (ACACA) and fatty acid synthase are also upregulated in many cancers, including GB, and play a role in tumorigenesis.29,30 The first committed step of lipid biosynthesis is catalyzed by ACACA. Inhibition of ACACA disrupts cancer stem cell self-renewal and growth and as such holds promise as a novel ...
d05a1663be3edc4
... • SRP is rod-like; one end it binds ER SS another end bonds between the large and small ribosomal subunits blocks elongation, stoping translation; this ensures that the protein is not sent to the cytoplasm (this is VERY important for lysosomal enzymes as they can be deadly if the cell puts them in ...
... • SRP is rod-like; one end it binds ER SS another end bonds between the large and small ribosomal subunits blocks elongation, stoping translation; this ensures that the protein is not sent to the cytoplasm (this is VERY important for lysosomal enzymes as they can be deadly if the cell puts them in ...
PDF - The Journal of Cell Biology
... Delamasure et al., 2002; Gay and Gangloff, 2007). Activation of Toll-1 triggers the degradation of the NF-κB inhibitor Cactus, enabling the nuclear translocation of the NF-κB homologues Dorsal and Dorsal-related immunity factor (Dif), which function as transcription factors. Other Tolls have also be ...
... Delamasure et al., 2002; Gay and Gangloff, 2007). Activation of Toll-1 triggers the degradation of the NF-κB inhibitor Cactus, enabling the nuclear translocation of the NF-κB homologues Dorsal and Dorsal-related immunity factor (Dif), which function as transcription factors. Other Tolls have also be ...
Serine phosphorylation of the cotton cytosolic pyruvate kinase
... Cotton is one of the most important economical crops cultivated globally. After undergoing a period of fast elongation (~ 20 days) and a secondary wall deposition (~ 30 days), trichomes initiated from cotton ovule epidermal cells develop into spinnable fibers, which is a great textile material with ...
... Cotton is one of the most important economical crops cultivated globally. After undergoing a period of fast elongation (~ 20 days) and a secondary wall deposition (~ 30 days), trichomes initiated from cotton ovule epidermal cells develop into spinnable fibers, which is a great textile material with ...
Reconstruction of Amino Acid Biosynthesis Pathways from the
... Hidemasa Bono, Hiroyuki Ogata, Susumu Goto, and Minoru Kanehisa1 Institute for Chemical Research, Kyoto University, Uji, Kyoto 611, Japan The complete genome sequence of an organism contains information that has not been fully utilized in the current prediction methods of gene functions, which are b ...
... Hidemasa Bono, Hiroyuki Ogata, Susumu Goto, and Minoru Kanehisa1 Institute for Chemical Research, Kyoto University, Uji, Kyoto 611, Japan The complete genome sequence of an organism contains information that has not been fully utilized in the current prediction methods of gene functions, which are b ...
Lesson20ProteinStructureSearches
... SAP (structure alignment) allows a profile to be influenced by secondary structure Useful to 3D PSSM in that threading decisions (which aa’s match to a profile) Homology based protein conformation enhanced by making better decisions on where to insert gaps/varying length loops ...
... SAP (structure alignment) allows a profile to be influenced by secondary structure Useful to 3D PSSM in that threading decisions (which aa’s match to a profile) Homology based protein conformation enhanced by making better decisions on where to insert gaps/varying length loops ...
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS)
... Phylogenetic and In-silico structural and functional analysis of RIP’s as immunolesioning agents resulting in selective interferences with ionic channels and receptors located on the neuronal cell surface. In contrast plant neurotoxins act inside the cells [6]. Other than the immunolesioning proper ...
... Phylogenetic and In-silico structural and functional analysis of RIP’s as immunolesioning agents resulting in selective interferences with ionic channels and receptors located on the neuronal cell surface. In contrast plant neurotoxins act inside the cells [6]. Other than the immunolesioning proper ...
Paracrine signalling

Paracrine signaling is a form of cell-cell communication in which a cell produces a signal to induce changes in nearby cells, altering the behavior or differentiation of those cells. Signaling molecules known as paracrine factors diffuse over a relatively short distance (local action), as opposed to endocrine factors (hormones which travel considerably longer distances via the circulatory system), juxtacrine interactions, and autocrine signaling. Cells that produce paracrine factors secrete them into the immediate extracellular environment. Factors then travel to nearby cells in which the gradient of factor received determines the outcome. However, the exact distance that paracrine factors can travel is not certain.Although paracrine signaling elicits a diverse array of responses in the induced cells, most paracrine factors utilize a relatively streamlined set of receptors and pathways. In fact, different organs in the body -even between different species - are known to utilize a similar sets of paracrine factors in differential development. The highly conserved receptors and pathways can be organized into four major families based on similar structures: Fibroblast growth factor (FGF) family, Hedgehog family, Wnt family, and TGF-β superfamily. Binding of a paracrine factor to its respective receptor initiates signal transduction cascades, eliciting different responses.