
Hedgehog and Dpp signaling induce cadherin Cad86C expression
... Fig. 2 – Cad86C is expressed in cells of the leading flank of the morphogenetic furrow and localizes to the subapical region. (A) A control eye imaginal disc hybridized with a Cad86C-specific RNA probe. A hybridization signal is detected in the region of the morphogenetic furrow. (B) An eye imaginal ...
... Fig. 2 – Cad86C is expressed in cells of the leading flank of the morphogenetic furrow and localizes to the subapical region. (A) A control eye imaginal disc hybridized with a Cad86C-specific RNA probe. A hybridization signal is detected in the region of the morphogenetic furrow. (B) An eye imaginal ...
INFORMATION FOR FOREIGN STUDENTS
... 5. Close the lid of the electrophoresis unit hermetically just after sample application and switch on the power at the required voltage. The electrophoresis will be run after 20 minutes. 6. When electrophoresis is complete, the power must be switched off, the electrophoresis unit is opened and the m ...
... 5. Close the lid of the electrophoresis unit hermetically just after sample application and switch on the power at the required voltage. The electrophoresis will be run after 20 minutes. 6. When electrophoresis is complete, the power must be switched off, the electrophoresis unit is opened and the m ...
Supplementary materials
... 3. Identification of gene duplications: Alignments of the Shewanella proteins were generated using Darwin 2.0 (6). Proteins were aligned over at least 83 amino acids or ≥70% of the sequence lengths. Strain specific duplications were identified from the data set as the proteins that had a better matc ...
... 3. Identification of gene duplications: Alignments of the Shewanella proteins were generated using Darwin 2.0 (6). Proteins were aligned over at least 83 amino acids or ≥70% of the sequence lengths. Strain specific duplications were identified from the data set as the proteins that had a better matc ...
full text pdf
... redox-based signaling can be controlled independently [30]. Specific compartment-based redox signaling, including that involved in chloroplast-to-nucleus and mitochondria-to-nucleus retrograde communication, and regulation of gene expression can be achieved by changes in the redox status of a given ...
... redox-based signaling can be controlled independently [30]. Specific compartment-based redox signaling, including that involved in chloroplast-to-nucleus and mitochondria-to-nucleus retrograde communication, and regulation of gene expression can be achieved by changes in the redox status of a given ...
trisphosphate specifically interacts with the phox homology domain
... translocation of PDK-1 to a place where it can phosphorylate and activate Akt (protein kinase B, PKB) (Stephens et al., 1998), which results in the increased phosphorylation of several substrates including glycogen synthase kinase-3 (GSK3), p70s6k and 4E-BP1 (Scott et al., 1998). These, in turn, act ...
... translocation of PDK-1 to a place where it can phosphorylate and activate Akt (protein kinase B, PKB) (Stephens et al., 1998), which results in the increased phosphorylation of several substrates including glycogen synthase kinase-3 (GSK3), p70s6k and 4E-BP1 (Scott et al., 1998). These, in turn, act ...
Self-association of the SET domains of human ALL-1 and of
... the gap and pair-rule genes and is later maintained by the trithorax and polycomb group genes, which function as transcriptional activators and repressors, respectively. ALL-1 contains several motifs shared with other proteins. These include: (a) three AT hook motifs which are known to bind to AT-ri ...
... the gap and pair-rule genes and is later maintained by the trithorax and polycomb group genes, which function as transcriptional activators and repressors, respectively. ALL-1 contains several motifs shared with other proteins. These include: (a) three AT hook motifs which are known to bind to AT-ri ...
endoplasmic reticulum stress and lipid metabolism
... unfolded or misfolded proteins due to inherited mutations, calcium-‐ or oxidative flux, the cell can be under (ER) stress. In 1988, a stress response to unfolded proteins was reported, wh ...
... unfolded or misfolded proteins due to inherited mutations, calcium-‐ or oxidative flux, the cell can be under (ER) stress. In 1988, a stress response to unfolded proteins was reported, wh ...
Overview of Protein Structure • The three
... The interior of proteins is hydrophobic, consisting primarily of aliphatic residues that are in intimate contact so as to exclude water. It is thought that exclusion of water from the hydrophobic protein interior is one of the principle forces stabilizing the native structure of proteins. However, t ...
... The interior of proteins is hydrophobic, consisting primarily of aliphatic residues that are in intimate contact so as to exclude water. It is thought that exclusion of water from the hydrophobic protein interior is one of the principle forces stabilizing the native structure of proteins. However, t ...
Coagulation in vitro
... useful model for coagulation, more recent evidence has shown that the pathways are not, in fact, redundant but are highly interconnected. For example, the tissue factor/VIIa complex activates not only factor X (as shown in Fig. 3) but also factor IX of the intrinsic pathway. Furthermore, patients wi ...
... useful model for coagulation, more recent evidence has shown that the pathways are not, in fact, redundant but are highly interconnected. For example, the tissue factor/VIIa complex activates not only factor X (as shown in Fig. 3) but also factor IX of the intrinsic pathway. Furthermore, patients wi ...
Improved Tolerance to Salt and Water Stress in
... mass and enter into a state that approaches suspended animation (Clegg, 1973; Crowe and Madin, 1974, 1975; Hinton, 1968). Desiccation tolerance has also been observed in some flowering plants, algae, fungi, bacteria, and most seeds of higher plants are desiccation tolerant (Billi and Potts, 2002; Cr ...
... mass and enter into a state that approaches suspended animation (Clegg, 1973; Crowe and Madin, 1974, 1975; Hinton, 1968). Desiccation tolerance has also been observed in some flowering plants, algae, fungi, bacteria, and most seeds of higher plants are desiccation tolerant (Billi and Potts, 2002; Cr ...
Pentose Phosphate Pathway - Berkeley MCB
... How is this pentose phosphate pathway regulated? NADPH which is generated in the oxidative branch of the pathway can feed back and inhibit the pathway. Glucose 6-phosphate can still be utilized by glycolysis. ...
... How is this pentose phosphate pathway regulated? NADPH which is generated in the oxidative branch of the pathway can feed back and inhibit the pathway. Glucose 6-phosphate can still be utilized by glycolysis. ...
Protein S-nitrosylation in photosynthetic organisms: A
... forbidness [34]. The reactions involving NO inside the cell are extremely important because they give rise to more reactive molecules, particularly nitrogen oxides (e.g. NO2, N2O3) and peroxynitrite (ONOO−), collectively named reactive nitrogen species (RNS). These molecules have much higher reactiv ...
... forbidness [34]. The reactions involving NO inside the cell are extremely important because they give rise to more reactive molecules, particularly nitrogen oxides (e.g. NO2, N2O3) and peroxynitrite (ONOO−), collectively named reactive nitrogen species (RNS). These molecules have much higher reactiv ...
CHEMCO M M
... by repetitive amino acid sequences, it is often possible to multimerize a smaller oligonucleotide sequence to prepare an artificial gene that codes for proteins of high molecular weight. This multimerization process can be considered as a polycondensation, which therefore results in a set of genes w ...
... by repetitive amino acid sequences, it is often possible to multimerize a smaller oligonucleotide sequence to prepare an artificial gene that codes for proteins of high molecular weight. This multimerization process can be considered as a polycondensation, which therefore results in a set of genes w ...
Relationship between relative protein value and some in vitro in
... Ramachandra et al., 1977; Marable and Sanzone, 1981). It has been demonstrated that mammalian intestine can take up small peptides in addition to free AAs. Several kinetic advantages associated with the small peptide absorption as against the free AA absorption (Adibi, 1971; Matthews et al., 1969), ...
... Ramachandra et al., 1977; Marable and Sanzone, 1981). It has been demonstrated that mammalian intestine can take up small peptides in addition to free AAs. Several kinetic advantages associated with the small peptide absorption as against the free AA absorption (Adibi, 1971; Matthews et al., 1969), ...
Unit 10 web
... • 15 different PNAH’s have been isolated from the outer layer of charcoal broiled steak • 8 micrograms of 1,2-benzopyrene per kilo of steak • Arise from decomposition of fat that drips on to the glowing charcoal and the subsequent vaporization of the hydrocarbons and deposition on the surface of the ...
... • 15 different PNAH’s have been isolated from the outer layer of charcoal broiled steak • 8 micrograms of 1,2-benzopyrene per kilo of steak • Arise from decomposition of fat that drips on to the glowing charcoal and the subsequent vaporization of the hydrocarbons and deposition on the surface of the ...
Specialized filopodia direct long-range transport of SHH
... the form of a particle that remains associated with the cell via long cytoplasmic extensions that span several cell diameters. We show that these cellular extensions are a specialized class of actin-based filopodia with novel cytoskeletal features that have not been previously described. Notably, pa ...
... the form of a particle that remains associated with the cell via long cytoplasmic extensions that span several cell diameters. We show that these cellular extensions are a specialized class of actin-based filopodia with novel cytoskeletal features that have not been previously described. Notably, pa ...
The role of carbohydrate in sperm
... number of different epitopes within the ZP3, i.e. gamete interaction is a process where recognition of gametes relies on multivalent ligand interactions. With regard to the molecular basis of cell adhesion, individual protein-carbohydrate interactions are thought to be very weak and often of broad s ...
... number of different epitopes within the ZP3, i.e. gamete interaction is a process where recognition of gametes relies on multivalent ligand interactions. With regard to the molecular basis of cell adhesion, individual protein-carbohydrate interactions are thought to be very weak and often of broad s ...
Protein and Amino Acids
... Enable absorption of A.A. and di-peptides Di-peptides are hydrolyzed into A.A. in gut wall NPN are also absorbed in S.I. ...
... Enable absorption of A.A. and di-peptides Di-peptides are hydrolyzed into A.A. in gut wall NPN are also absorbed in S.I. ...
MASE1 and MASE2: Two Novel Integral Membrane Sensory Domains
... Tel. +1 301 435 5910, Fax +1 301 435 7794, E-Mail [email protected] ...
... Tel. +1 301 435 5910, Fax +1 301 435 7794, E-Mail [email protected] ...
Redox signals as a language of interorganellar
... redox-based signaling can be controlled independently [30]. Specific compartment-based redox signaling, including that involved in chloroplast-to-nucleus and mitochondria-to-nucleus retrograde communication, and regulation of gene expression can be achieved by changes in the redox status of a given ...
... redox-based signaling can be controlled independently [30]. Specific compartment-based redox signaling, including that involved in chloroplast-to-nucleus and mitochondria-to-nucleus retrograde communication, and regulation of gene expression can be achieved by changes in the redox status of a given ...
PROTECTION OF MESOPORE-ADSORBED TYROSINE FROM
... the presence of a single amino acid (such as tyrosine) as an energy source. (Thompson, Daly) • Pa can grow as both planktonic (suspended cells) and biofilm (attached) cultures. • Tyrosine has an aromatic structure that can adsorb to mesoporous alumina (Zimmerman). • Alumina is a common mineral in so ...
... the presence of a single amino acid (such as tyrosine) as an energy source. (Thompson, Daly) • Pa can grow as both planktonic (suspended cells) and biofilm (attached) cultures. • Tyrosine has an aromatic structure that can adsorb to mesoporous alumina (Zimmerman). • Alumina is a common mineral in so ...
X-ray Crystallographic Structure of Ibuprofen Bound to Human
... regulate the uptake of intestinal fatty acids in rats. These proteins are most abundantly found in the tissues engaged in active lipid metabolism. Adipocyte fatty acid binding protein or aP2 is a member of this family, which is found in adipocytes and macrophages and integrates metabolic and inflamm ...
... regulate the uptake of intestinal fatty acids in rats. These proteins are most abundantly found in the tissues engaged in active lipid metabolism. Adipocyte fatty acid binding protein or aP2 is a member of this family, which is found in adipocytes and macrophages and integrates metabolic and inflamm ...
4.3. monosaccharides
... strong interactions between water molecules and the polyanionic complex. It is present in cartilage and tendon, vitreous humour (eyes), extracellular matrix, mucosal surface and synovial fluid. Chondroitin sulfate. It promotes tension resistance in cartilage, tendon and arteries. It is present in ...
... strong interactions between water molecules and the polyanionic complex. It is present in cartilage and tendon, vitreous humour (eyes), extracellular matrix, mucosal surface and synovial fluid. Chondroitin sulfate. It promotes tension resistance in cartilage, tendon and arteries. It is present in ...
Paracrine signalling

Paracrine signaling is a form of cell-cell communication in which a cell produces a signal to induce changes in nearby cells, altering the behavior or differentiation of those cells. Signaling molecules known as paracrine factors diffuse over a relatively short distance (local action), as opposed to endocrine factors (hormones which travel considerably longer distances via the circulatory system), juxtacrine interactions, and autocrine signaling. Cells that produce paracrine factors secrete them into the immediate extracellular environment. Factors then travel to nearby cells in which the gradient of factor received determines the outcome. However, the exact distance that paracrine factors can travel is not certain.Although paracrine signaling elicits a diverse array of responses in the induced cells, most paracrine factors utilize a relatively streamlined set of receptors and pathways. In fact, different organs in the body -even between different species - are known to utilize a similar sets of paracrine factors in differential development. The highly conserved receptors and pathways can be organized into four major families based on similar structures: Fibroblast growth factor (FGF) family, Hedgehog family, Wnt family, and TGF-β superfamily. Binding of a paracrine factor to its respective receptor initiates signal transduction cascades, eliciting different responses.