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Hedgehog and Dpp signaling induce cadherin Cad86C expression
Hedgehog and Dpp signaling induce cadherin Cad86C expression

... Fig. 2 – Cad86C is expressed in cells of the leading flank of the morphogenetic furrow and localizes to the subapical region. (A) A control eye imaginal disc hybridized with a Cad86C-specific RNA probe. A hybridization signal is detected in the region of the morphogenetic furrow. (B) An eye imaginal ...
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INFORMATION FOR FOREIGN STUDENTS
INFORMATION FOR FOREIGN STUDENTS

... 5. Close the lid of the electrophoresis unit hermetically just after sample application and switch on the power at the required voltage. The electrophoresis will be run after 20 minutes. 6. When electrophoresis is complete, the power must be switched off, the electrophoresis unit is opened and the m ...
Supplementary materials
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... 3. Identification of gene duplications: Alignments of the Shewanella proteins were generated using Darwin 2.0 (6). Proteins were aligned over at least 83 amino acids or ≥70% of the sequence lengths. Strain specific duplications were identified from the data set as the proteins that had a better matc ...
full text pdf
full text pdf

... redox-based signaling can be controlled independently [30]. Specific compartment-based redox signaling, including that involved in chloroplast-to-nucleus and mitochondria-to-nucleus retrograde communication, and regulation of gene expression can be achieved by changes in the redox status of a given ...
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trisphosphate specifically interacts with the phox homology domain

... translocation of PDK-1 to a place where it can phosphorylate and activate Akt (protein kinase B, PKB) (Stephens et al., 1998), which results in the increased phosphorylation of several substrates including glycogen synthase kinase-3 (GSK3), p70s6k and 4E-BP1 (Scott et al., 1998). These, in turn, act ...
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Unit 10 web
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MASE1 and MASE2: Two Novel Integral Membrane Sensory Domains
MASE1 and MASE2: Two Novel Integral Membrane Sensory Domains

... Tel. +1 301 435 5910, Fax +1 301 435 7794, E-Mail [email protected] ...
Redox signals as a language of interorganellar
Redox signals as a language of interorganellar

... redox-based signaling can be controlled independently [30]. Specific compartment-based redox signaling, including that involved in chloroplast-to-nucleus and mitochondria-to-nucleus retrograde communication, and regulation of gene expression can be achieved by changes in the redox status of a given ...
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PROTECTION OF MESOPORE-ADSORBED TYROSINE FROM

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X-ray Crystallographic Structure of Ibuprofen Bound to Human
X-ray Crystallographic Structure of Ibuprofen Bound to Human

... regulate the uptake of intestinal fatty acids in rats. These proteins are most abundantly found in the tissues engaged in active lipid metabolism. Adipocyte fatty acid binding protein or aP2 is a member of this family, which is found in adipocytes and macrophages and integrates metabolic and inflamm ...
4.3. monosaccharides
4.3. monosaccharides

... strong interactions between water molecules and the polyanionic complex. It is present in cartilage and tendon, vitreous humour (eyes), extracellular matrix, mucosal surface and synovial fluid.  Chondroitin sulfate. It promotes tension resistance in cartilage, tendon and arteries. It is present in ...
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Paracrine signalling



Paracrine signaling is a form of cell-cell communication in which a cell produces a signal to induce changes in nearby cells, altering the behavior or differentiation of those cells. Signaling molecules known as paracrine factors diffuse over a relatively short distance (local action), as opposed to endocrine factors (hormones which travel considerably longer distances via the circulatory system), juxtacrine interactions, and autocrine signaling. Cells that produce paracrine factors secrete them into the immediate extracellular environment. Factors then travel to nearby cells in which the gradient of factor received determines the outcome. However, the exact distance that paracrine factors can travel is not certain.Although paracrine signaling elicits a diverse array of responses in the induced cells, most paracrine factors utilize a relatively streamlined set of receptors and pathways. In fact, different organs in the body -even between different species - are known to utilize a similar sets of paracrine factors in differential development. The highly conserved receptors and pathways can be organized into four major families based on similar structures: Fibroblast growth factor (FGF) family, Hedgehog family, Wnt family, and TGF-β superfamily. Binding of a paracrine factor to its respective receptor initiates signal transduction cascades, eliciting different responses.
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