Computational Protein Design as a Cost Function Network
... size of the combinatorial sequence space is however clearly out of reach of current experimental methods, even for small proteins. Computational protein design (CPD) methods therefore try to intelligently guide this process by producing a collection of proteins, intended to be rich in functional pro ...
... size of the combinatorial sequence space is however clearly out of reach of current experimental methods, even for small proteins. Computational protein design (CPD) methods therefore try to intelligently guide this process by producing a collection of proteins, intended to be rich in functional pro ...
XBRAINоаWhey Protein Isolate Worlds finest Only the Finest Quality
... percent of the protein content. Whey as a group of proteins is the fraction that separates out during cheese making. This fraction is purified to different concentrations depending on the endproduct desired and varies in protein, lactose, immunoglobulins, minerals and fat content. Of all protein ...
... percent of the protein content. Whey as a group of proteins is the fraction that separates out during cheese making. This fraction is purified to different concentrations depending on the endproduct desired and varies in protein, lactose, immunoglobulins, minerals and fat content. Of all protein ...
Translation
... As mRNA binds, IF-3 helps to correctly position the complex such that the tRNAfMet interacts via base pairing with the mRNA initiation codon (AUG). A region of mRNA upstream of the initiation codon, the Shine-Dalgarno sequence, base pairs with the 3' end of the 16S rRNA. This positions the 30S ri ...
... As mRNA binds, IF-3 helps to correctly position the complex such that the tRNAfMet interacts via base pairing with the mRNA initiation codon (AUG). A region of mRNA upstream of the initiation codon, the Shine-Dalgarno sequence, base pairs with the 3' end of the 16S rRNA. This positions the 30S ri ...
ATP-Binding Cassette (ABC) Transporters in Human Metabolism
... the ABC transporter chamber. Both the cell-surface and inner membrane pores are estimated to be relatively large, allowing for simultaneous translocation of multiple molecules. This may explain why the ABCA1 pathway generates diffuse and irregular structures that protrude from the plasma membrane an ...
... the ABC transporter chamber. Both the cell-surface and inner membrane pores are estimated to be relatively large, allowing for simultaneous translocation of multiple molecules. This may explain why the ABCA1 pathway generates diffuse and irregular structures that protrude from the plasma membrane an ...
Infrared spectroscopic studies: from small molecules to large.
... Herschel in 1800. However, until 1940’s, IR studies involved only water and small organic molecules, because of the long measurement times and inaccessibility of the instruments. In 1940s came the first commercially available infrared spectrometers, which relied on prisms to act as dispersive elemen ...
... Herschel in 1800. However, until 1940’s, IR studies involved only water and small organic molecules, because of the long measurement times and inaccessibility of the instruments. In 1940s came the first commercially available infrared spectrometers, which relied on prisms to act as dispersive elemen ...
The Production, Purification, and Bioactivity of Recombinant Bovine
... not extended to bovine IFNa,, cDNA (5). Finally, the organization of up-stream promoter regions of the bTP1 genes is very different from that of IFNaM (Hansen, T. R., J. Bixby, and R. M. Roberts, unpublished results). As different subtypes of the short (166-amino acid) IFNa, have been made available ...
... not extended to bovine IFNa,, cDNA (5). Finally, the organization of up-stream promoter regions of the bTP1 genes is very different from that of IFNaM (Hansen, T. R., J. Bixby, and R. M. Roberts, unpublished results). As different subtypes of the short (166-amino acid) IFNa, have been made available ...
Open Reading Frame (ORF) finding - Manatee
... -The background color of this box will be gold if the protein is in the characterized table and grey if it is not. -The top bar lists the percent identity/similarity and the organism from which the protein comes (if available). -The bottom section lists all of the accession numbers and names for all ...
... -The background color of this box will be gold if the protein is in the characterized table and grey if it is not. -The top bar lists the percent identity/similarity and the organism from which the protein comes (if available). -The bottom section lists all of the accession numbers and names for all ...
Reaction Engineering - AAU -uddannelser, forskning og
... 2) Semi-continuous: fed batch-gradual addition of concentrated nutrients so that the culture volume and product amount are increased (e.g. industrial production of baker’s yeast); Perfusion-addition of medium to the culture and withdrawal of an equal volume of used cell-free medium (e.g. animal cell ...
... 2) Semi-continuous: fed batch-gradual addition of concentrated nutrients so that the culture volume and product amount are increased (e.g. industrial production of baker’s yeast); Perfusion-addition of medium to the culture and withdrawal of an equal volume of used cell-free medium (e.g. animal cell ...
pdf-version
... refresh refresh the protein visualization export download protein visualization as PDF, SVG, or PNG file email send a link to the current Protter visualization via email open in UniProt open currently visualized protein in UniProt (for proteins entered "by accession") or BLAST currently visualized p ...
... refresh refresh the protein visualization export download protein visualization as PDF, SVG, or PNG file email send a link to the current Protter visualization via email open in UniProt open currently visualized protein in UniProt (for proteins entered "by accession") or BLAST currently visualized p ...
Biosensor-based engineering of biosynthetic pathways
... RNA that bind small molecule ligands to control the stability of the mRNA transcript, directly affecting the translation of the encoded genes [23,24]. Sensors based on fluorescence resonance energy transfer (FRET) [25] use a conformational change in a protein domain brought about by ligand binding t ...
... RNA that bind small molecule ligands to control the stability of the mRNA transcript, directly affecting the translation of the encoded genes [23,24]. Sensors based on fluorescence resonance energy transfer (FRET) [25] use a conformational change in a protein domain brought about by ligand binding t ...
Signalling crosstalk in light stress and immune reactions in plants
... with green algae has suggested a possible mechanism explaining this tight relationship. Expression of a nuclearencoded reporter gene coupled to a H2O2 sensitive promoter was shown to respond not only to the levels of exogenously added H2O2 but also to light-induced photosynthetic electron transfer, ...
... with green algae has suggested a possible mechanism explaining this tight relationship. Expression of a nuclearencoded reporter gene coupled to a H2O2 sensitive promoter was shown to respond not only to the levels of exogenously added H2O2 but also to light-induced photosynthetic electron transfer, ...
All 3 fates of pyruvate from glycolysis provide for the regeneration of
... discovery of the enzyme that starts the conversion of glycogen to glucose. ...
... discovery of the enzyme that starts the conversion of glycogen to glucose. ...
The stability and nuclear localization of the transcription factor RAP2
... proteins and lipids is reduced (Geigenberger 2003). Moreover, energy-saving pathways are favoured over those that are more expensive in terms of ATP (Bologa et al. 2003). When oxygen becomes limiting for oxidative phosphorylation, ATP production relies on fermentative metabolism. Its activation coin ...
... proteins and lipids is reduced (Geigenberger 2003). Moreover, energy-saving pathways are favoured over those that are more expensive in terms of ATP (Bologa et al. 2003). When oxygen becomes limiting for oxidative phosphorylation, ATP production relies on fermentative metabolism. Its activation coin ...
pentose phosphate pathway
... 1. Control by hormones c). Insulin: -High levels of glucose induce release of insulin from β-cells of islets of Langerhan in the pancreas. ...
... 1. Control by hormones c). Insulin: -High levels of glucose induce release of insulin from β-cells of islets of Langerhan in the pancreas. ...
Protein Functional Annotation - Institute for Genome Sciences
... anything (another protein, an HMM, etc.) is removed. If both don’t match anything, other considerations such as presence in a putative operon and potential start codon quality are considered. Small regions of overlap are allowed (circle).! ...
... anything (another protein, an HMM, etc.) is removed. If both don’t match anything, other considerations such as presence in a putative operon and potential start codon quality are considered. Small regions of overlap are allowed (circle).! ...
- Wiley Online Library
... to light decreased transcript levels in ME cells (Lai et al., 2002). Interestingly, cis-elements that affect BS-specific expression of ME are different for F. bidentis and a close C4 relative, F. trinervia. In F. bidentis, the endogenous NADPME gene may require elements within the coding region at t ...
... to light decreased transcript levels in ME cells (Lai et al., 2002). Interestingly, cis-elements that affect BS-specific expression of ME are different for F. bidentis and a close C4 relative, F. trinervia. In F. bidentis, the endogenous NADPME gene may require elements within the coding region at t ...
Physiological adaptations of Saccharomyces cerevisiae evolved for
... some light on this issue. The second most repressed protein was Rpl7B, a component of the large subunit of the ribosome. This was the only ribosomal protein showing a significant change in expression of >1.5 fold in any direction. Rpl7B is highly similar to Rpl7A which shows no change in expression. ...
... some light on this issue. The second most repressed protein was Rpl7B, a component of the large subunit of the ribosome. This was the only ribosomal protein showing a significant change in expression of >1.5 fold in any direction. Rpl7B is highly similar to Rpl7A which shows no change in expression. ...
PROTEIN CHEMISTRY
... forces that control protein folding. Attractive van der Waals forces involve the interactions among induced dipoles that arise from fluctuations in the charge densities that occur between adjacent uncharged nonbonded atoms. Repulsive van der Waals forces involve the interactions that occur when unch ...
... forces that control protein folding. Attractive van der Waals forces involve the interactions among induced dipoles that arise from fluctuations in the charge densities that occur between adjacent uncharged nonbonded atoms. Repulsive van der Waals forces involve the interactions that occur when unch ...
Comparing Sequences of Fluorescent Proteins Using
... Fluorescent Proteins” from the page below: http://www.nwabr.org/teacher-center/introductory-bioinformatics-genetic-testing#resources 3. Perform a nucleotide BLAST alignment as explained in the Student Handout, “Instructions for Aligning Sequences with BLAST,” Steps 1-13. Use “Euk-Green-Fluorescent-P ...
... Fluorescent Proteins” from the page below: http://www.nwabr.org/teacher-center/introductory-bioinformatics-genetic-testing#resources 3. Perform a nucleotide BLAST alignment as explained in the Student Handout, “Instructions for Aligning Sequences with BLAST,” Steps 1-13. Use “Euk-Green-Fluorescent-P ...
WorkSheet_14
... Vitamin A and Vision 1. Identify provitamin A / -carotene, vitamin A / retinol, vitamin A ester / retinol palmitate, retinaldehyde / retinal and retinoic acid (all-trans and 9-cis) in terms of their positions on the pathway of vitamin A metabolism. Delineate which reactions are reversible and which ...
... Vitamin A and Vision 1. Identify provitamin A / -carotene, vitamin A / retinol, vitamin A ester / retinol palmitate, retinaldehyde / retinal and retinoic acid (all-trans and 9-cis) in terms of their positions on the pathway of vitamin A metabolism. Delineate which reactions are reversible and which ...
EF-G-GTP
... protein, although a GAP may contribute an essential active site residue. GEFs & GAPs may be separately regulated. Unique GEFs and GAPs interact with different GTP-binding proteins ...
... protein, although a GAP may contribute an essential active site residue. GEFs & GAPs may be separately regulated. Unique GEFs and GAPs interact with different GTP-binding proteins ...
Glycolysis 2
... ATP binding to the allosteric effector site is highest when the protein is in the T state which functions to decrease fructose-6-P binding to the catalytic site AMP binding to the allosteric effector site serves to stabilize the R state, and thereby stimulates the production of fructose-1,6-BP by AT ...
... ATP binding to the allosteric effector site is highest when the protein is in the T state which functions to decrease fructose-6-P binding to the catalytic site AMP binding to the allosteric effector site serves to stabilize the R state, and thereby stimulates the production of fructose-1,6-BP by AT ...
Paracrine signalling
Paracrine signaling is a form of cell-cell communication in which a cell produces a signal to induce changes in nearby cells, altering the behavior or differentiation of those cells. Signaling molecules known as paracrine factors diffuse over a relatively short distance (local action), as opposed to endocrine factors (hormones which travel considerably longer distances via the circulatory system), juxtacrine interactions, and autocrine signaling. Cells that produce paracrine factors secrete them into the immediate extracellular environment. Factors then travel to nearby cells in which the gradient of factor received determines the outcome. However, the exact distance that paracrine factors can travel is not certain.Although paracrine signaling elicits a diverse array of responses in the induced cells, most paracrine factors utilize a relatively streamlined set of receptors and pathways. In fact, different organs in the body -even between different species - are known to utilize a similar sets of paracrine factors in differential development. The highly conserved receptors and pathways can be organized into four major families based on similar structures: Fibroblast growth factor (FGF) family, Hedgehog family, Wnt family, and TGF-β superfamily. Binding of a paracrine factor to its respective receptor initiates signal transduction cascades, eliciting different responses.