Managing people in sport organisations
... Phosphorylation of tyrosines on dimerized receptors (R) following hormone (H) binding provides docking sites for the attachment of proteins that transduce the hormonal signal. The growth factor binding protein 2 (GRB2) binds to a phosphorylated tyrosine in the receptor, and binds at its other end to ...
... Phosphorylation of tyrosines on dimerized receptors (R) following hormone (H) binding provides docking sites for the attachment of proteins that transduce the hormonal signal. The growth factor binding protein 2 (GRB2) binds to a phosphorylated tyrosine in the receptor, and binds at its other end to ...
Repetition Summary of last lecture Energy Cell Respiration
... f at t y acyl gr oups ar e t r ansf er r ed f r om f at t y acyl CoA and t r anspor t ed acr oss t he inner m em br ane via a on t he m at r ix side. Pyr uvat e is conver t ed t o acet yl CoA wit h t he f or m at ion of NADH, and f at t y acids ...
... f at t y acyl gr oups ar e t r ansf er r ed f r om f at t y acyl CoA and t r anspor t ed acr oss t he inner m em br ane via a on t he m at r ix side. Pyr uvat e is conver t ed t o acet yl CoA wit h t he f or m at ion of NADH, and f at t y acids ...
S1 Text.
... step of plastid intrinsic FA-synthesis (for overview, see [1]). Thus, the latter finding is well in line with increased plastid FA-synthesis, due to increased FA-export via over-expressed FAX1 proteins in flower tissue. A focus of regulation in fax1 knockout flowers was for genes functioning in pho ...
... step of plastid intrinsic FA-synthesis (for overview, see [1]). Thus, the latter finding is well in line with increased plastid FA-synthesis, due to increased FA-export via over-expressed FAX1 proteins in flower tissue. A focus of regulation in fax1 knockout flowers was for genes functioning in pho ...
投影片 1
... Both entail a droplet containing purified protein, buffer, and precipitant being allowed to equilibrate with a larger reservoir containing similar buffers and precipitants in higher concentrations. Initially, the droplet of protein solution contains an insufficient concentration of precipitant for c ...
... Both entail a droplet containing purified protein, buffer, and precipitant being allowed to equilibrate with a larger reservoir containing similar buffers and precipitants in higher concentrations. Initially, the droplet of protein solution contains an insufficient concentration of precipitant for c ...
- Wiley Online Library
... SC population, numerous studies have identified similar small subpopulations of ‘stem-like’ cells, which have been referred to as side-population cells, reserve cells, LRCs, and/or muscle-derived stem cells. The system is further complicated by the discovery that nonmyogenic cells can also contribut ...
... SC population, numerous studies have identified similar small subpopulations of ‘stem-like’ cells, which have been referred to as side-population cells, reserve cells, LRCs, and/or muscle-derived stem cells. The system is further complicated by the discovery that nonmyogenic cells can also contribut ...
Introduction to Carbohydrates
... - Therefore, tissues that respond to more than one chemical signal must have several different receptors, each of which can be linked to adenylyl cyclase Note: certain toxins, as that produced by Vibrio cholera, can also activate the adenylyl cyclase cascade, with potentially disastrous consequences ...
... - Therefore, tissues that respond to more than one chemical signal must have several different receptors, each of which can be linked to adenylyl cyclase Note: certain toxins, as that produced by Vibrio cholera, can also activate the adenylyl cyclase cascade, with potentially disastrous consequences ...
View/Open - Oregon State University
... Highlights Glycolysis II 1. Glycolysis is a metabolic pathway for the breakdown (catabolism) of glucose and related sugars. The pathway requires two ATPs to start the process and generates 4 ATPS (for a net of two ATPs) per glucose. Also generated during glycolysis are two NADH and two molecules of ...
... Highlights Glycolysis II 1. Glycolysis is a metabolic pathway for the breakdown (catabolism) of glucose and related sugars. The pathway requires two ATPs to start the process and generates 4 ATPS (for a net of two ATPs) per glucose. Also generated during glycolysis are two NADH and two molecules of ...
Mechanism Of Hormonal Action:1
... Is the signal produced as a result of hormone binding to its cell membrane receptor. It mediates the effects of the hormone. ...
... Is the signal produced as a result of hormone binding to its cell membrane receptor. It mediates the effects of the hormone. ...
Amyotrophic Lateral Sclerosis SOD1
... http://www.jimmunol.org/content/190/10/5187.full#ref-list-1 Information about subscribing to The Journal of Immunology is online at: http://jimmunol.org/subscription ...
... http://www.jimmunol.org/content/190/10/5187.full#ref-list-1 Information about subscribing to The Journal of Immunology is online at: http://jimmunol.org/subscription ...
Metabolism of Leukotrienes: The Linear Biosynthetic Pathway
... in a number of tissues, most notably the lung, as well as brain, heart, and spleen. Two distinct types of enzymatically-produced LT have been identified: Cysteinyl (or peptidyl) leukotrienes LTC4, LTD4, and LTE4 (originally identified as the slow reacting substances of anaphylaxis), and the dihydrox ...
... in a number of tissues, most notably the lung, as well as brain, heart, and spleen. Two distinct types of enzymatically-produced LT have been identified: Cysteinyl (or peptidyl) leukotrienes LTC4, LTD4, and LTE4 (originally identified as the slow reacting substances of anaphylaxis), and the dihydrox ...
Preview Sample 1
... A. Cells serve as the living building blocks of the body. B. The average human cell is about one hundred times smaller than the smallest particle visible by the unaided eye. C. Inanimate chemical molecules are organized within each cell into a living entity. D. Cells are generally colorless and tran ...
... A. Cells serve as the living building blocks of the body. B. The average human cell is about one hundred times smaller than the smallest particle visible by the unaided eye. C. Inanimate chemical molecules are organized within each cell into a living entity. D. Cells are generally colorless and tran ...
Pleiotropy of leptin receptor signalling is defined by distinct roles of
... actions of leptin have also been described [3]. Two effects have been particularly well studied: the stimulation of proinflammatory immune responses by direct action on T-lymphocytes [4,5], and the inhibition of insulin secretion from pancreatic beta cells [6–9]. As a class I cytokine receptor, LEPRb ...
... actions of leptin have also been described [3]. Two effects have been particularly well studied: the stimulation of proinflammatory immune responses by direct action on T-lymphocytes [4,5], and the inhibition of insulin secretion from pancreatic beta cells [6–9]. As a class I cytokine receptor, LEPRb ...
uric acid stimulates vascular smooth muscle cell proliferation by
... acid, [3H]thymidine incorporation and the endothelin-1 (ET-1) gene expression was examined. Antioxidants pretreatment on uric acid-induced extracellular signal-regulated kinase (ERK) phosphorylation were performed to elucidate the redox-sensitive pathway in proliferation and ET-1 gene expression. Cr ...
... acid, [3H]thymidine incorporation and the endothelin-1 (ET-1) gene expression was examined. Antioxidants pretreatment on uric acid-induced extracellular signal-regulated kinase (ERK) phosphorylation were performed to elucidate the redox-sensitive pathway in proliferation and ET-1 gene expression. Cr ...
"Neurotransmitter Receptors in the Postsynaptic Neuron". In
... divided into two broad classes based on their transduction mechanisms following receptor activation. Rapid synaptic transmission is mediated by neurotransmitter receptors that are ligand-gated ion channels. The interaction of the neurotransmitter with the respective neurotransmitter receptor for a l ...
... divided into two broad classes based on their transduction mechanisms following receptor activation. Rapid synaptic transmission is mediated by neurotransmitter receptors that are ligand-gated ion channels. The interaction of the neurotransmitter with the respective neurotransmitter receptor for a l ...
Catalytic Nitrene Transfer onto Isocyanide by a Redox
... Catalytic Nitrene Transfer onto Isocyanide by a Redox-Active Ligand Zirconium Complex Andy I. Nguyen Mentor: Alan Heyduk In an effort to bridge the gap between late- and early-metal reactivity, we have used redox-active ligands that are capable of multielectron valence changes. These ligands on form ...
... Catalytic Nitrene Transfer onto Isocyanide by a Redox-Active Ligand Zirconium Complex Andy I. Nguyen Mentor: Alan Heyduk In an effort to bridge the gap between late- and early-metal reactivity, we have used redox-active ligands that are capable of multielectron valence changes. These ligands on form ...
Minus end - Website Staff UI
... All three types of cytoskeletal filaments are formed by assemblying (polimerisation) of their subunits through noncovalent linkages ...
... All three types of cytoskeletal filaments are formed by assemblying (polimerisation) of their subunits through noncovalent linkages ...
Alternative isoleucine synthesis pathway in
... cce_0248 gene in Cyanothece 51142 exhibits 53 % identity to the gene encoding citramalate synthase (CimA, GSU1798) from Geobacter sulfurreducens. Reverse-transcription PCR indicated that the cce_0248 gene is expressed and its transcriptional level is lower in medium with isoleucine than in isoleucin ...
... cce_0248 gene in Cyanothece 51142 exhibits 53 % identity to the gene encoding citramalate synthase (CimA, GSU1798) from Geobacter sulfurreducens. Reverse-transcription PCR indicated that the cce_0248 gene is expressed and its transcriptional level is lower in medium with isoleucine than in isoleucin ...
Dark induction and subcellular localization of the pathogenesis
... protoplasts of ethylene-treated tobacco leaves and in cell suspension cultures. Protoplasts were isolated from leaves exposed to ethylene for 72 h. Vacuoles were then released from protoplasts and purified by centrifugation on a discontinuous Ficoll gradient. The purity of the vacuolar preparation w ...
... protoplasts of ethylene-treated tobacco leaves and in cell suspension cultures. Protoplasts were isolated from leaves exposed to ethylene for 72 h. Vacuoles were then released from protoplasts and purified by centrifugation on a discontinuous Ficoll gradient. The purity of the vacuolar preparation w ...
Regulation of Tcell receptor signaling by the actin cytoskeleton and
... into the cytoplasm following TCR triggering. Blebbistatinmediated cross-linking is induced by short-wavelength light (52, 57), such as that used for Fura-2 imaging. This clouds the interpretation of results that use Fura-2 and blebbistatin (48). Other than myosin II, little is known about how other ...
... into the cytoplasm following TCR triggering. Blebbistatinmediated cross-linking is induced by short-wavelength light (52, 57), such as that used for Fura-2 imaging. This clouds the interpretation of results that use Fura-2 and blebbistatin (48). Other than myosin II, little is known about how other ...
TTR
... Targets: Additional role of TH carriers in drugdrug interactions for other drugs • Because >99% of T3/T4 are proteinbound in plasma, carrier protein disregulation may lead to large variations in free T3/T4 • Factors that may change TBG concentration: – pregnancy, estrogen-containing medication (TBG ...
... Targets: Additional role of TH carriers in drugdrug interactions for other drugs • Because >99% of T3/T4 are proteinbound in plasma, carrier protein disregulation may lead to large variations in free T3/T4 • Factors that may change TBG concentration: – pregnancy, estrogen-containing medication (TBG ...
Document
... •Structural domains in the polypeptide troponin C, two separate calcium-binding domains ...
... •Structural domains in the polypeptide troponin C, two separate calcium-binding domains ...
Computational Pharmacology - Carnegie Mellon School of
... have we understood how aspirin works, and how it might be improved http://www.rcsb.org/pdb/molecules/pdb17_1.html ...
... have we understood how aspirin works, and how it might be improved http://www.rcsb.org/pdb/molecules/pdb17_1.html ...
Paracrine signalling
Paracrine signaling is a form of cell-cell communication in which a cell produces a signal to induce changes in nearby cells, altering the behavior or differentiation of those cells. Signaling molecules known as paracrine factors diffuse over a relatively short distance (local action), as opposed to endocrine factors (hormones which travel considerably longer distances via the circulatory system), juxtacrine interactions, and autocrine signaling. Cells that produce paracrine factors secrete them into the immediate extracellular environment. Factors then travel to nearby cells in which the gradient of factor received determines the outcome. However, the exact distance that paracrine factors can travel is not certain.Although paracrine signaling elicits a diverse array of responses in the induced cells, most paracrine factors utilize a relatively streamlined set of receptors and pathways. In fact, different organs in the body -even between different species - are known to utilize a similar sets of paracrine factors in differential development. The highly conserved receptors and pathways can be organized into four major families based on similar structures: Fibroblast growth factor (FGF) family, Hedgehog family, Wnt family, and TGF-β superfamily. Binding of a paracrine factor to its respective receptor initiates signal transduction cascades, eliciting different responses.