ESTUDIO DE LOS MECANISMOS DE INHIBICIÓN DE LA ACTIVIDAD CARNITINA PALMITOILTRANSFERASA 1
... Residues Conserved in Malonyl-CoA Inhibited Versus Noninhibited Carnitine-Choline Acyltransferases—An exhaustive analysis of the presence of residues shared by all the malonylCoA-regulated enzymes of the carnitine-choline acyltransferase family versus the malonyl-CoA nonregulated members of the same ...
... Residues Conserved in Malonyl-CoA Inhibited Versus Noninhibited Carnitine-Choline Acyltransferases—An exhaustive analysis of the presence of residues shared by all the malonylCoA-regulated enzymes of the carnitine-choline acyltransferase family versus the malonyl-CoA nonregulated members of the same ...
Heterotrophic cultures
... carbon sources dissolved in the culture media. Heterotrophy is defined as the use of organic compounds for growth (Droop, 1974). Heterotrophs are organisms whose substrate and energy needs are derived from organic compounds synthesized by other organisms (Kaplan et al., 1986). The basic culture medi ...
... carbon sources dissolved in the culture media. Heterotrophy is defined as the use of organic compounds for growth (Droop, 1974). Heterotrophs are organisms whose substrate and energy needs are derived from organic compounds synthesized by other organisms (Kaplan et al., 1986). The basic culture medi ...
9 The AMP-activated protein kinase: more than an energy sensor
... concentrations corresponding to the therapeutic range in the portal vein [23]. Thiazolidinediones, another class of anti-diabetic compounds, activate AMPK through an increase in AMP/ATP ratio, which also seems to result from an inhibition of mitochondrial respiration [22]. In relation to the effect ...
... concentrations corresponding to the therapeutic range in the portal vein [23]. Thiazolidinediones, another class of anti-diabetic compounds, activate AMPK through an increase in AMP/ATP ratio, which also seems to result from an inhibition of mitochondrial respiration [22]. In relation to the effect ...
Global transcriptional control by glucose and
... as cells enter into stationary phase and is modulated in response to different environmental signals, such as temperature, biotin limitation, the presence of antibiotics, of butyric acid or butanol and of certain amino acids like cysteine or proline (14). This indicates a correlation between environ ...
... as cells enter into stationary phase and is modulated in response to different environmental signals, such as temperature, biotin limitation, the presence of antibiotics, of butyric acid or butanol and of certain amino acids like cysteine or proline (14). This indicates a correlation between environ ...
Studies of the Physiology, Pharmacology, and Biochemistry of the
... In at least three instances, the growth substance activity of a plant concentrate has been found to reside in part in materials not identical with IAA. In all of these instances, however, the material in question has turned out to be a derivative of or otherwise closely related to IAA. The first of ...
... In at least three instances, the growth substance activity of a plant concentrate has been found to reside in part in materials not identical with IAA. In all of these instances, however, the material in question has turned out to be a derivative of or otherwise closely related to IAA. The first of ...
7) The role of cobalt in vitamin B12
... Provide no energy and are unchanged by the reaction they catalyse Body does not synthesize vitamins – must be part of the diet Vitamins are essential molecules for enzyme activity – deficiency leads to death ...
... Provide no energy and are unchanged by the reaction they catalyse Body does not synthesize vitamins – must be part of the diet Vitamins are essential molecules for enzyme activity – deficiency leads to death ...
Conformational changes in actin–myosin isoforms probed by Ni(II
... Crucial information concerning conformational changes that occur during the mechanochemical cycle of actin– myosin complexes is lacking due to the difficulties encountered in obtaining their three-dimensional structures. To obtain such information, we employed a solution-based approach through the re ...
... Crucial information concerning conformational changes that occur during the mechanochemical cycle of actin– myosin complexes is lacking due to the difficulties encountered in obtaining their three-dimensional structures. To obtain such information, we employed a solution-based approach through the re ...
Rapamycin increases mitochondrial efficiency by mtDNA
... the introgressed genotypes could only result from main effects of the distinct mtDNAs or ...
... the introgressed genotypes could only result from main effects of the distinct mtDNAs or ...
E. Coli MurG: A Paradigm for a Superfamily of
... using the hanging-drop vapor diffusion method in a NaMES buffer (pH 6.5) containing 0.5 M (NH4)2SO4 and 0.2% Triton X-100. Triclinic crystals belonging to the P1 space group and having two molecules per asymmetric unit grew to a typical size of 0.2 mm × 0.1 mm × 0.1 mm within a week. The crystal str ...
... using the hanging-drop vapor diffusion method in a NaMES buffer (pH 6.5) containing 0.5 M (NH4)2SO4 and 0.2% Triton X-100. Triclinic crystals belonging to the P1 space group and having two molecules per asymmetric unit grew to a typical size of 0.2 mm × 0.1 mm × 0.1 mm within a week. The crystal str ...
Structure of bacterial luciferase
... in the case of the luciferase from k" han,eyi). The two subunits are clearly homologous (see below) [2,15], but the single active center is on the 0t subunit (for a review, see [2]). The role of the ]3 subunit is not yet clear, but it is essential for a high quantum yield reaction [2]. Alignment of ...
... in the case of the luciferase from k" han,eyi). The two subunits are clearly homologous (see below) [2,15], but the single active center is on the 0t subunit (for a review, see [2]). The role of the ]3 subunit is not yet clear, but it is essential for a high quantum yield reaction [2]. Alignment of ...
The Unusual Binding Properties of the Third Distinct Teleost
... duplication of ER early in the teleost lineage after the divergence of ray- and lobe-finned fishes. These three subtypes were subsequently identified in zebrafish (19). The acER ortholog in zebrafish is now designated ERb or ESR2b (previously ER1) to comply with official zebrafish nomenclature r ...
... duplication of ER early in the teleost lineage after the divergence of ray- and lobe-finned fishes. These three subtypes were subsequently identified in zebrafish (19). The acER ortholog in zebrafish is now designated ERb or ESR2b (previously ER1) to comply with official zebrafish nomenclature r ...
Evolution of Conifer Diterpene Synthases
... bicyclization of GGPP followed by rearrangement of a (+)-copalyl diphosphate intermediate at two discrete class II and class I active sites. In contrast, similar diterpenes of gibberellin primary (i.e. general) metabolism are produced by the consecutive activity of two monofunctional class II and cl ...
... bicyclization of GGPP followed by rearrangement of a (+)-copalyl diphosphate intermediate at two discrete class II and class I active sites. In contrast, similar diterpenes of gibberellin primary (i.e. general) metabolism are produced by the consecutive activity of two monofunctional class II and cl ...
Flavin coenzymes
... Flavin coenzymes: – Are tightly bound to the enzyme – Exist in any of three different redox states – Change color according to the switch of the redox states – Participate in one-electron and two-electron transfer reactions – Work with different electron acceptors and donors (e.g. NAD) 28 ...
... Flavin coenzymes: – Are tightly bound to the enzyme – Exist in any of three different redox states – Change color according to the switch of the redox states – Participate in one-electron and two-electron transfer reactions – Work with different electron acceptors and donors (e.g. NAD) 28 ...
Biochemistry 1997 Baird
... (Brechue et al., 1991; Lucci et al., 1983). CA IV is also localized in pulmonary endothelial cells where it catalyzes the dehydration of serum bicarbonate to CO2 (Whitney & Briggle, 1982). Furthermore, CA IV is found in the endothelial cells of an ocular capillary bed (Hageman et al., 1991; Maren et ...
... (Brechue et al., 1991; Lucci et al., 1983). CA IV is also localized in pulmonary endothelial cells where it catalyzes the dehydration of serum bicarbonate to CO2 (Whitney & Briggle, 1982). Furthermore, CA IV is found in the endothelial cells of an ocular capillary bed (Hageman et al., 1991; Maren et ...
Ethylene is involved in strawberry fruit ripening in an organ
... Interestingly, this last increase is accompanied by an enhanced respiration rate that resembles that which occurs in climacteric fruits at the onset of ripening (Iannetta et al., 2006). In the strawberry, two ACO genes (FaACO1 and FaACO2) and three ethylene receptor genes, two type I (FaEtr1 and FaE ...
... Interestingly, this last increase is accompanied by an enhanced respiration rate that resembles that which occurs in climacteric fruits at the onset of ripening (Iannetta et al., 2006). In the strawberry, two ACO genes (FaACO1 and FaACO2) and three ethylene receptor genes, two type I (FaEtr1 and FaE ...
Involvement of Polyamine Catabolism in the Regulation of Glucose
... activated polyamine catabolism-mediated depletion in the cellular ATP pool which activated the cellular energy sensor, 5’-AMP-activated protein kinase (AMPK) and PGC-1D. These results suggest that the enhancement of cellular ATP consumption is an efficient way to reduce body WAT mass and improve glu ...
... activated polyamine catabolism-mediated depletion in the cellular ATP pool which activated the cellular energy sensor, 5’-AMP-activated protein kinase (AMPK) and PGC-1D. These results suggest that the enhancement of cellular ATP consumption is an efficient way to reduce body WAT mass and improve glu ...
Susan Viggiano and Michael S. Cosgrove
... Although MLL1 has served as a paradigm for the mechanism of action of human SET1 family enzymes, several recent reports suggest different family members are controlled by distinct regulatory mechanisms. For example, although the MLL1 core complex has predominantly mono- and dimethyltransferase activ ...
... Although MLL1 has served as a paradigm for the mechanism of action of human SET1 family enzymes, several recent reports suggest different family members are controlled by distinct regulatory mechanisms. For example, although the MLL1 core complex has predominantly mono- and dimethyltransferase activ ...
Review: can diet influence the selective advantage of mitochondrial
... complexes for each electron pair transferred, less ATP made by the ATP synthase for each proton driven through it (collectively called slip reactions), uncoupling proteins whose function is to catalyse a regulated inducible proton conductance and leak of protons across the membranes [32]. In the pre ...
... complexes for each electron pair transferred, less ATP made by the ATP synthase for each proton driven through it (collectively called slip reactions), uncoupling proteins whose function is to catalyse a regulated inducible proton conductance and leak of protons across the membranes [32]. In the pre ...
PelleyStep1ReviewInBiochemistry
... glycogen granules have an abnormal structure. The patient most likely has a deficiency of what enzyme? A. B. C. D. E. ...
... glycogen granules have an abnormal structure. The patient most likely has a deficiency of what enzyme? A. B. C. D. E. ...
Flux analysis in central carbon metabolism in plants
... experiments that employ U-13C (uniformly 13C-labeled) substrates. It was shown that the enumeration of feasible bondomers in a metabolic network reduced the number of bondomer balances 3-fold. This resulted in a simplified system that offers the advantages of faster computation, and easier flux iden ...
... experiments that employ U-13C (uniformly 13C-labeled) substrates. It was shown that the enumeration of feasible bondomers in a metabolic network reduced the number of bondomer balances 3-fold. This resulted in a simplified system that offers the advantages of faster computation, and easier flux iden ...
Mechanistic Studies of Two Selected Flavin
... Choline oxidase catalyzes the flavin-dependent, two-step oxidation of choline to glycine betaine via the formation of an aldehyde intermediate. The oxidation of choline includes two reductive half-reactions followed by oxidative half-reactions. In the first oxidation reaction, the alcohol substrate ...
... Choline oxidase catalyzes the flavin-dependent, two-step oxidation of choline to glycine betaine via the formation of an aldehyde intermediate. The oxidation of choline includes two reductive half-reactions followed by oxidative half-reactions. In the first oxidation reaction, the alcohol substrate ...
The metabolic basis of Candida albicans
... Recent studies have elucidated the signal transduction pathways and quorum sensing molecules that affect the morphological transition of C. albicans. The metabolic mechanisms that recognize, and respond to, such signaling molecules and promote the morphological changes at a system level, however, re ...
... Recent studies have elucidated the signal transduction pathways and quorum sensing molecules that affect the morphological transition of C. albicans. The metabolic mechanisms that recognize, and respond to, such signaling molecules and promote the morphological changes at a system level, however, re ...