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C. Protein
C. Protein

... Sometimes proteins have non-peptide groups attached, which can be called prosthetic groups or cofactors. Proteins can also work together to achieve a particular function, and they often associate to form stable complexes. Protein Structure Most proteins fold into unique 3-dimensional structures. The ...
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Slide 1

... • Protein synthesis • Variety of other components( Purine,pyrimidines etc) • Histamine • Biological fuel(10% energy production) ...
Lecture 3 (BY 14)
Lecture 3 (BY 14)

... Dehydration synthesis • Form polymers from subunits • Enzymes remove -OH from one molecule, H from another, form bond between two molecules • Discarded atoms can join to form _____ ...
PROTEINS - Hyndland Secondary School
PROTEINS - Hyndland Secondary School

... Tertiary Structure • The overall folded shape of a protein held together by (usually) weak forces. – Hydrogen bonding which doesn’t form secondary structure – Hydrophobic interactions • Place non-polar amino acids inside protein • Polar amino acids on surface ...
Amino Acid R (neutral form) -NH3 -CO2H Side chain Glycine, Gly
Amino Acid R (neutral form) -NH3 -CO2H Side chain Glycine, Gly

... Goal: Our goal in this activity is to apply what we learned about amino acids and the primary structure of proteins and begin to consider how proteins fold into the 3-dimensional structures that we observe in our bodies. This activity will specifically investigate the chemistry of amino acid side ch ...
energy currency for cell - Hermantown Community Schools
energy currency for cell - Hermantown Community Schools

... caused by histone modification and DNA methylation other than changes in the DNA sequence (mutations) • Regulates gene expression w/o changing the DNA • Changes have been shown to be heritable. ...
Nitrogen Metabolism - Oregon State University
Nitrogen Metabolism - Oregon State University

... Evidence for Gastric and Esophageal Cancer Risk Nitrosamines in Tobacco Form From Nicotine NNK is Nicotine Derived and Important in Carcinogenesis NNK in Tobacco and E-cigarettes NNK Activation by P-450 Activated Signaling Cascades & Uncontrolled Growth ...
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... 10. Catabolic pathways (e.g. lac operon) that break down complex substances into more usable units are usually regulated by the: a. end products of the pathway b. substrate (or related compound) of an enzyme in the pathway c. other metabolites that are limiting d. attenuation e. none of the above 1 ...
The Nobel Prize in Chemistry 1948 Arne Tiselius
The Nobel Prize in Chemistry 1948 Arne Tiselius

... The Nobel Prize in Chemistry 1948 Arne Tiselius ...
Nitrogen Balance
Nitrogen Balance

... Pyruvate • The carbon skeletons of six amino acids are converted in whole or in part to pyruvate. • These are alanine, tryptophan, cysteine, serine, glycine, and threonine. • All carbon atoms of gly, ala, cys, and ser are converted to pyruvate. • Only two carbon atoms of thr and three of trp form py ...
Biochemistry Test Review KEY
Biochemistry Test Review KEY

... 12. What is the name of the structure above and what is its function? Nucleic acid 13. What is a common element found in all organic compounds? Carbon 14. What effect does pH levels have on a certain enzyme? Slows or speeds up rate of reaction, as well as the modifies the enzyme’s shape 15. Describ ...
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Control of intra-cellular (enzyme regulator)

... Fatty acid biosynthesis occurs in the cytosol, whereas fatty acid oxidation takes place within mitochondria Segregation of certain metabolic pathways within specialized cell types can provide further physical compartmentation. ...
biochemistry-micromolecules
biochemistry-micromolecules

... Act as biological CATALYSTS:  speed up the rate of a chemical reaction by lowering the activation energy of the reaction  Activation Energy: energy needed to transform reactant substances into product substances Reaction pathway without enzyme ...
Standard Genetic Code
Standard Genetic Code

...  DNA/RNA – for storing information about how to make proteins The building blocks for proteins are 20 different types of amino acids, and these amino acids are strung together one after another when a protein is built. The instructions for building each particular protein is encoded in DNA in the c ...
Worksheet 1 - Ch. 2, 3 - Iowa State University
Worksheet 1 - Ch. 2, 3 - Iowa State University

... b. Peptide bonds form between __________ and ___________ functional groups. 3. This is an image of an aquaporin protein; it lets water into the cell through a tunnel. a. What structure does it have? b. Determine whether polar and nonpolar amino acids would be located on the inside or outer layer of ...
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... – The junk (parts of the DNA that are noncoding regions) called introns need to be cut out. – Exons (coding regions) are then stuck together. This is the correct concise message. ...
Fatty Acids: The lipid building blocks: The common building block for
Fatty Acids: The lipid building blocks: The common building block for

... proteins, which are also polymeric. The subunits which make-up Proteins are Amino Acids. The amino acids are joined together by dehydration synthesis to form chains, which are hundreds of amino acids long; called proteins. Proteins function as enzymes or as structural units in cells. They do most of ...
Catabolism of the branched
Catabolism of the branched

... hydroxylase, PKU is the most common clinically encountered inborn error of amino acid metabolism (prevalence 1:15,000). • Hyperphenylalaninemia may also be caused by deficiencies in any of the several enzymes required to synthesize BH4, or in dihydropteridine (BH2) reductase, which regenerates BH4 f ...
Chapter 30
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... Second genetic code • Sequence and structures of RNA oligos that mimic the acceptor stem and confer specific aminoacylations constitute an operational RNA code for amino acids • Such as code may have predated the genetic code ...
Biochemistry Notes
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Encoding Amino Acids • mRNA codes for amino acids
Encoding Amino Acids • mRNA codes for amino acids

... o There would be 42, or 16, possible combinations o This is still not enough to unambiguously represent all 20 amino acids • Finally, suppose combinations of 3 RNA nucleotides represented amino acids o That would be 43, or 64, possible combinations o This is more than enough to represent all 20 amin ...
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Exam 1

... They will all proceed equally fast because they are all enzyme catalyzed. Cannot be determined from these data. ...
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Appendices Enzyme Endurance Review of Protein Structure Great

... evolved so that the binding of a small ligand can induce a significant change in protein shape. Most enzymes are allosteric proteins that can exist in two conformations that differ in catalytic activity, and the enzyme can be turned on or off by ligands that bind to a distinct regulatory site to sta ...
Amino Acids - University of Houston
Amino Acids - University of Houston

... pK1  2.2 while pK2  9.4, pKR for R group pK’s In the physiological pH range, both NH2 and COOH are completely ionized They can act as either an acid or a base ...
Quale Vita? - uniroma1.it
Quale Vita? - uniroma1.it

... Water warmed up to 1000C ...
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Amino acid synthesis

Amino acid synthesis is the set of biochemical processes (metabolic pathways) by which the various amino acids are produced from other compounds. The substrates for these processes are various compounds in the organism's diet or growth media. Not all organisms are able to synthesise all amino acids. Humans are excellent example of this, since humans can only synthesise 11 of the 20 standard amino acids (aka non-essential amino acid), and in time of accelerated growth, arginine, can be considered an essential amino acid.A fundamental problem for biological systems is to obtain nitrogen in an easily usable form. This problem is solved by certain microorganisms capable of reducing the inert N≡N molecule (nitrogen gas) to two molecules of ammonia in one of the most remarkable reactions in biochemistry. Ammonia is the source of nitrogen for all the amino acids. The carbon backbones come from the glycolytic pathway, the pentose phosphate pathway, or the citric acid cycle.In amino acid production, one encounters an important problem in biosynthesis, namely stereochemical control. Because all amino acids except glycine are chiral, biosynthetic pathways must generate the correct isomer with high fidelity. In each of the 19 pathways for the generation of chiral amino acids, the stereochemistry at the α-carbon atom is established by a transamination reaction that involves pyridoxal phosphate. Almost all the transaminases that catalyze these reactions descend from a common ancestor, illustrating once again that effective solutions to biochemical problems are retained throughout evolution.Biosynthetic pathways are often highly regulated such that building-blocks are synthesized only when supplies are low. Very often, a high concentration of the final product of a pathway inhibits the activity of enzymes that function early in the pathway. Often present are allosteric enzymes capable of sensing and responding to concentrations of regulatory species. These enzymes are similar in functional properties to aspartate transcarbamoylase and its regulators. Feedback and allosteric mechanisms ensure that all twenty amino acids are maintained in sufficient amounts for protein synthesis and other processes.
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