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Genetics and Heredity
Genetics and Heredity

... Tay-Sachs disease is caused by a dysfunctional enzyme that fails to break down brain lipids of a certain class. Is proportionately high incidence of TaySachs disease among Ashkenazic Jews, Jewish people whose ancestors lived in central Europe Sickle-cell disease, which affects one out of 400 Africa ...
Lecture 5
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... RNA consists of a sugar-phosphate backbone, with nucleotides attached to the 1' carbon of the sugar. The differences between DNA and RNA are that:  RNA has a hydroxyl group on the 2' carbon of the sugar.  Not like DNA uses thymine (T), RNA uses uracil (U).  Because of the extra hydroxyl group on ...
lecture 3
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... RNAi in flies 1. Express a fold back RNA from a transgene. ...
Document
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PowerPoint Presentation - No Slide Title
PowerPoint Presentation - No Slide Title

... Agarose gel electrophoresis can be used to investigate an individual’s genotype directly. If two alleles have sequence differences that change a restriction enzyme recognition site, then the size differences of the DNA fragments from a restriction digest can tell the researcher which alleles an ind ...
Clike here - University of Evansville Faculty Web sites
Clike here - University of Evansville Faculty Web sites

... Agarose gel electrophoresis can be used to investigate an individual’s genotype directly. If two alleles have sequence differences that change a restriction enzyme recognition site, then the size differences of the DNA fragments from a restriction digest can tell the researcher which alleles an ind ...
lesson viii - MisterSyracuse.com
lesson viii - MisterSyracuse.com

... 1. So we want to make a copy of DNA. DNA is double-stranded, but why? 2. So we don’t need a molecule that is so stable. This molecule isn’t going to be around that long. In fact, we don’t want it to be around that long! 3. So we need to make a copy of DNA, which we’re going to do using RNA. RNA has ...
Chapter 15
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... must mate. 3. Individuals with advantageous traits survive to pass the traits on to their offspring. 4. There is an origin of the species. ...
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Introduction to DNA Function and transcription

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Amino acid substitution and protein structure

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Supplementary methods
Supplementary methods

... 1.9 ± 0.2 times longer than WT and faster growth can be stimulated by restoring opaA on a plasmid (data not shown). Therefore OpaA performs functions which are essential, but can be bypassed by suppressor mutations. Yet OpaA is still required for optimal growth as would be expected for a coordinator ...
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pCMV-DsRed-Express Vector

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Ligation and Transformation

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Chapter 3 Review Questions
Chapter 3 Review Questions

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... c. Describe the secondary structure composition of this protein. Alpha helices. d. It is known that almost all helices are buried inside the membrane. Use this information to estimate the thickness of the membrane. (33-37 A, depending on the points chosen. Units must be given.) e. How was this struc ...
notes
notes

... destroy lipids, proteins, carbs, and RNA  transformation still occurred BUT when the treated the “juice” with enzymes to destroy DNA  transformation did not occur therefore, DNA was the TRANSFORMING FACTOR Scientists were still skeptical about the genetic material of higher organisms. ...
microsatellite marker analysis in the treatment and diagnosis of
microsatellite marker analysis in the treatment and diagnosis of

... sequences, which consist of about 10ñ50 copies of motifs of 1ñ6 bp and occur frequently in all eucaryotic genomes. Microsatellites are characterized by considerable polymorphism due to variation in the number of repeat units. This polymorphism can be easily detected by polymerase chain reaction (PCR ...
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STUDY GUIDE –Intro to Cell Biology
STUDY GUIDE –Intro to Cell Biology

... 4. NUCLEIC ACIDS – INFORMATION molecules made of NUCLEOTIDE subunits EX: DNA – DOUBLE stranded: has DEOXYRIBOSE SUGAR and A, T, C, & G RNA - SINGLE stranded; has RIBOSE SUGAR and A, U, C, & G In a DNA molecule which nitrogen bases always bond with each other? A-T and G-C ...
DNA and the Genetic Code
DNA and the Genetic Code

... Transcription is the synthesis of mRNA (messenger RNA) from DNA The two DNA strands separate from one another. One strand is used for replication. The other is used for transcription. mRNA is the complement strand of the original DNA except with thymine replaced with uracil (U). mRNA carries genetic ...
aminoacids 2
aminoacids 2

... (MSUD) is a rare (1:185,000), autosomal recessive disorder in which there is a partial or complete deficiency in branched-chain α-keto acid dehydrogenase, an enzyme complex that decarboxylates leucine, isoleucine, and valine Accumulation of these A.A. in the blood, causing a toxic effect that interf ...
Lect 6 JF 2012.pptx
Lect 6 JF 2012.pptx

... 4.  It was modified again when it was discovered that some proteins contain more than one polypeptide chain each of which is encoded by a separate gene e.g. hemoglobin one gene codes for one polypeptide Beadle and Tatum won the Nobel Prize in 1958 ...
Chemical Organization of Life
Chemical Organization of Life

...  Secondary structure,  found in most proteins  consists of coils and folds in the polypeptide chain  Tertiary structure  determined by interactions among various side chains (R groups) ...
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Point mutation



A point mutation, or single base modification, is a type of mutation that causes a single nucleotide base change, insertion, or deletion of the genetic material, DNA or RNA. The term frameshift mutation indicates the addition or deletion of a base pair. A point mutant is an individual that is affected by a point mutation.Repeat induced point mutations are recurring point mutations, discussed below.
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