Anti-platelets
... • Cyclic peptide inhibitor of the fibrinogen binding site on GpIIb/IIIa receptor • Short duration of action: 6-12 hrs • Given with aspirin and heparin • Use: – Acute coronary syndrome – Angioplastic coronary interventions • Adverse effects: – Bleeding (10%) – Thrombocytopenia (0.5-1%) 3) Tirofiban • ...
... • Cyclic peptide inhibitor of the fibrinogen binding site on GpIIb/IIIa receptor • Short duration of action: 6-12 hrs • Given with aspirin and heparin • Use: – Acute coronary syndrome – Angioplastic coronary interventions • Adverse effects: – Bleeding (10%) – Thrombocytopenia (0.5-1%) 3) Tirofiban • ...
15. Drug-Induced Torsade de Pointes
... Although a normal range can be meaningfully defined for any scheme that is not seriously biased, the range may need be uselessly imprecise if the scheme does not take account of pertinent cofactors. This was demonstrated in the example of the single normal range for adult weight. 6.02. What is meant ...
... Although a normal range can be meaningfully defined for any scheme that is not seriously biased, the range may need be uselessly imprecise if the scheme does not take account of pertinent cofactors. This was demonstrated in the example of the single normal range for adult weight. 6.02. What is meant ...
O-Nervous System I
... Ganglion – a cluster of nerve cell bodies in PNS. Nucleus – gray matter in CNS with common function. ...
... Ganglion – a cluster of nerve cell bodies in PNS. Nucleus – gray matter in CNS with common function. ...
Nerve activates contraction
... Warm-Up • Name as many structures of the nervous system as you can • What do you think the major functions of the nervous system are? • Name one other body system and how you think it works with the nervous system ...
... Warm-Up • Name as many structures of the nervous system as you can • What do you think the major functions of the nervous system are? • Name one other body system and how you think it works with the nervous system ...
Anatomy and Neuroscience Research Projects for 2013
... department’s Honours Information Session, which is held mid September (details of the time and location will be advertised on our website from late August). This session is an opportunity to meet and talk with supervisors from all of the research laboratories in the department. Information about pro ...
... department’s Honours Information Session, which is held mid September (details of the time and location will be advertised on our website from late August). This session is an opportunity to meet and talk with supervisors from all of the research laboratories in the department. Information about pro ...
Narcan Overview - Telco House Bed & Breakfast
... push; repeat as indicated (per protocol) SC; repeat as indicated (per protocol) ...
... push; repeat as indicated (per protocol) SC; repeat as indicated (per protocol) ...
FDA
... • Once a drug has EU marketing authorisation, it is ‘licensed’, ‘registered’ or ‘approved’. All these terms mean the same thing. This means the company can market the drug in any EU country - but they don’t have to. For one reason or another, they may choose to market the drug in some countries but ...
... • Once a drug has EU marketing authorisation, it is ‘licensed’, ‘registered’ or ‘approved’. All these terms mean the same thing. This means the company can market the drug in any EU country - but they don’t have to. For one reason or another, they may choose to market the drug in some countries but ...
pharmacokinetics-5
... and is very slowly excreted can pose just as many problems as one that is susceptible to metabolism. • If the effects of the drug could last too long then it would cause both: → Toxicity → Lingering side effects Therefore, designing drugs with decreased chemical and metabolic stability can sometimes ...
... and is very slowly excreted can pose just as many problems as one that is susceptible to metabolism. • If the effects of the drug could last too long then it would cause both: → Toxicity → Lingering side effects Therefore, designing drugs with decreased chemical and metabolic stability can sometimes ...
McGovern Institute for Brain Research
... full investigators and three associate members (as of June 2010). Professor Feng, who was previously an associate professor at Duke University, studies the formation and function of synaptic connections and their disruption in mouse models of human brain disorders. He has developed a variety of gene ...
... full investigators and three associate members (as of June 2010). Professor Feng, who was previously an associate professor at Duke University, studies the formation and function of synaptic connections and their disruption in mouse models of human brain disorders. He has developed a variety of gene ...
THE NEURON
... An impulse begins when a neuron is stimulated by another neuron or by the environment. ...
... An impulse begins when a neuron is stimulated by another neuron or by the environment. ...
A Quick Note
... Transport routes Paracellular and transcellular routes For hydrophilic drugs: pore pathway (influenced by the physiological changes in the thickness of the vaginal epithelium) thinning of the epithelium and a pore like widening of the intercellular channels Insulin administration (effect of b ...
... Transport routes Paracellular and transcellular routes For hydrophilic drugs: pore pathway (influenced by the physiological changes in the thickness of the vaginal epithelium) thinning of the epithelium and a pore like widening of the intercellular channels Insulin administration (effect of b ...
HIV Negative
... Australian, and Dutch studies, patients on AZT developed severe anemia, requiring multiple blood transfusions just to stay alive. In the Dutch study, three-quarters of the patients on AZT died. Well, AZT wasn’t the only drug being used at ICC. The other was Nevirapine, which is marketed under the br ...
... Australian, and Dutch studies, patients on AZT developed severe anemia, requiring multiple blood transfusions just to stay alive. In the Dutch study, three-quarters of the patients on AZT died. Well, AZT wasn’t the only drug being used at ICC. The other was Nevirapine, which is marketed under the br ...
Sleep and metabolism: Role of hypothalamic
... sleep quantity. For example, chronic sleep loss is a state of reduced REM sleep but relatively preserved slow-wave sleep. More specific clinical evidence that sleep is an important factor for feeding or metabolism may be derived from the fact that pathological conditions in which sleep is pathologica ...
... sleep quantity. For example, chronic sleep loss is a state of reduced REM sleep but relatively preserved slow-wave sleep. More specific clinical evidence that sleep is an important factor for feeding or metabolism may be derived from the fact that pathological conditions in which sleep is pathologica ...
Arylalkylamine Drugs of Abuse: An Overview of Drug
... substituent is increased, N-monomethylation provides a curious exception; N-monomethylamphetamine or methamphetamine is at least as potent as amphetamine in (1)amphetamine-trained animals and, as with amphetamine itself, the S(1)-isomer is several times more potent than the R(2)-isomer (see Fig. 3 f ...
... substituent is increased, N-monomethylation provides a curious exception; N-monomethylamphetamine or methamphetamine is at least as potent as amphetamine in (1)amphetamine-trained animals and, as with amphetamine itself, the S(1)-isomer is several times more potent than the R(2)-isomer (see Fig. 3 f ...
Quiz Answers - RISE at Duke
... A. Correct-but there's more! Oxidation of ethanol involves the donation of 2 electrons in the form of H atoms to an acceptor molecule (sometimes this is oxygen, but not always). The acceptor molecule becomes reduced, because its charge is now reduced by the acceptance of the 2 electrons. B. No-you g ...
... A. Correct-but there's more! Oxidation of ethanol involves the donation of 2 electrons in the form of H atoms to an acceptor molecule (sometimes this is oxygen, but not always). The acceptor molecule becomes reduced, because its charge is now reduced by the acceptance of the 2 electrons. B. No-you g ...
Noradrenergic Modulation of Activity in a Vocal Control Nucleus In
... rapidly and reversibly decreased firing for the majority of neurons, to the extent that spontaneous activity was often abolished. This was likely a direct effect on the cell recorded, because it occurred with blockade of fast excitatory and inhibitory synaptic transmission or of all synaptic transmi ...
... rapidly and reversibly decreased firing for the majority of neurons, to the extent that spontaneous activity was often abolished. This was likely a direct effect on the cell recorded, because it occurred with blockade of fast excitatory and inhibitory synaptic transmission or of all synaptic transmi ...
The prefrontal cortex (PFC) is responsible for higher
... Valentino RJ (2013). This finding suggests that morphological changes may arise from a NE dependent mechanism. In the case that neurochemical changes are identical to those induced from restraint stress and isolation stress, it would imply that layer V pyramidal cells respond differently to chronic ...
... Valentino RJ (2013). This finding suggests that morphological changes may arise from a NE dependent mechanism. In the case that neurochemical changes are identical to those induced from restraint stress and isolation stress, it would imply that layer V pyramidal cells respond differently to chronic ...
Infancy: Physical Development
... Brain Development in Infancy • Myelination contributes to what infants are able to do. • Reflexive functions such as breathing due to myelination • Myelination of motor pathways allows neonates to show stereotyped reflexes. • Myelination will allow the disorganized movements of the neonate to come ...
... Brain Development in Infancy • Myelination contributes to what infants are able to do. • Reflexive functions such as breathing due to myelination • Myelination of motor pathways allows neonates to show stereotyped reflexes. • Myelination will allow the disorganized movements of the neonate to come ...
Pharmacology 19c – Epilepsy and Anticonvulsants
... 25% have epilepsy resistant to medical treatment Costs the NHS £1bn/year The characteristic symptom in epilepsy is recurrent unprovoked seizures. This consists of excessive synchronised discharge of a set of cerebral neurones. These are normally sudden and transient. Clinical manifestations depe ...
... 25% have epilepsy resistant to medical treatment Costs the NHS £1bn/year The characteristic symptom in epilepsy is recurrent unprovoked seizures. This consists of excessive synchronised discharge of a set of cerebral neurones. These are normally sudden and transient. Clinical manifestations depe ...
What is a Seizure?
... What causes epilepsy? In about 70% of people with epilepsy, the cause is not ...
... What causes epilepsy? In about 70% of people with epilepsy, the cause is not ...
Ch12.Nervous.Tissue
... – Peripheral nerves link all regions of body to CNS – Ganglia are clusters of neuronal cell bodies ...
... – Peripheral nerves link all regions of body to CNS – Ganglia are clusters of neuronal cell bodies ...
sample-2 - Philadelphia University Jordan
... some basic knowledge of the key aspects of the lecture material and can attempt to solve familiar problems (18 marks). Question-7: (2 marks) Ketorolac is a non-steroidal anti-inflammatory agent, it will be –vely charged in blood, design a prodrug for it that will be only protonated in blood (changin ...
... some basic knowledge of the key aspects of the lecture material and can attempt to solve familiar problems (18 marks). Question-7: (2 marks) Ketorolac is a non-steroidal anti-inflammatory agent, it will be –vely charged in blood, design a prodrug for it that will be only protonated in blood (changin ...
Induced Phototoxicity
... the local intensity of the relevant wavelengths and individual factors, such as skin type and drug handling. Phototoxic reactions develop in most individuals if they are exposed to sufficient amounts of light and drug. Typically, they appear as an exaggerated sunburn response. Photosensitivity react ...
... the local intensity of the relevant wavelengths and individual factors, such as skin type and drug handling. Phototoxic reactions develop in most individuals if they are exposed to sufficient amounts of light and drug. Typically, they appear as an exaggerated sunburn response. Photosensitivity react ...