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Script Notes - AmeriHealth Caritas Pennsylvania
Script Notes - AmeriHealth Caritas Pennsylvania

... Vimizim is intended to provide the exogenous enzyme N-acetylgalactosamine-6-sulfatase that will be taken up into the lysosomes and increase the catabolism of the GAGs KS and C6S. ...
Nervous System
Nervous System

... Nerve Tissue Neurons Nerve Cells transmit electochemical signals (nerve impulses) ...
Desensitization of Cannabinoid-Mediated Presynaptic Inhibition of
Desensitization of Cannabinoid-Mediated Presynaptic Inhibition of

... for Win55,212-2, suggesting a reciprocal ability to produce heterologous desensitization. The long-term changes in synaptic function that accompany chronic cannabinoid exposure will be an important factor in evaluating the therapeutic potential of these drugs and will provide insight into the role o ...
The glucocorticoids (GCs) secreted from the adrenal cortex (corti
The glucocorticoids (GCs) secreted from the adrenal cortex (corti

... ulated by GCs. Their pivotal role during development is further supported by experimental studies reporting protective effects of dexamethasone in a neonatal model of hypoxic-ischemic brain injury (Tuor et al. 1993, 1995). Also considering the fact that lack of corticosterone induced apoptosis in de ...
Opioids in Persistent Pain
Opioids in Persistent Pain

... manifested by a drug class specific withdrawal syndrome that can be produced by abrupt cessation, rapid dose reduction decreasing blood level of the drug or administration of an antagonist.  Tolerance - is a state of adaptation in which exposure to a drug induces changes that result in a diminution ...
Chapter 11 Objectives
Chapter 11 Objectives

... Many people who require dental care never go to the dentist because of fear and apprehension and for these patients antianxiety medicine may be necessary. The dose of a particular antianxiety agent is vastly different for each patient. The amount needed is poorly determined by the degree of anxiety ...
Nanocochleate - a new approach in lipid drug delivery
Nanocochleate - a new approach in lipid drug delivery

... with liposomes did not. This result suggests that cochleates’ edges made them fuse with the cell surfaces as compared to edge free liposomes. This  abilty makes it a potential therapeutic drug carrier.  Keywords: Cationic Drug, Hydrophilic, Hydrophobic, Nanocochleate, Liposomes.  ...
Lecture 12 Gastrointestinal Agents Chapters 41 & 42
Lecture 12 Gastrointestinal Agents Chapters 41 & 42

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SOP 006 Reporting Procedures - University of Kansas Medical Center
SOP 006 Reporting Procedures - University of Kansas Medical Center

... submission of a form entitled “Biannual Progress Report for RDRC-Approved Research Protocol Subject to Requirements of 21 CFR 361.1. This interim document will need to include: a. A summary of all patients recruited into each protocol and subgroup. b. The number of extra doses of radiopharmaceutical ...
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2004 Guide to Psychiatric Drug Interactions
2004 Guide to Psychiatric Drug Interactions

... acute infection) to preventive or maintenance therapy for chronic illnesses as diverse as major depressive disorder (MDD), schizophrenia, Alzheimer’s disease, hypertension, human immunodeficiency virus infection, and atherosclerosis. As a result of this change in focus, patients are more likely to b ...
Notes and comments - Paradigm Shift Now
Notes and comments - Paradigm Shift Now

... and remembering. According to Hebbian neurophysiology, an object is memorized by suitably increasing the synaptic strengths. This provides a basis for a theory of associative learning and memory. Despite the progress made in understanding brain function using the NN paradigm, the NN approach can be ...
Antimicrobial Agents (Sulfonamides and Quinolones 1 )
Antimicrobial Agents (Sulfonamides and Quinolones 1 )

... • Slow acetylators, Immunocompromised, and patients with brain tumors undergoing radiotherapy with concomitant antiepileptics are among those at most risk. • Patients with sulfonamide-induced toxic epidermal necrolysis have been shown to have a slow acetylator genotype that results in increased prod ...
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Evaluating Hallucinogenic or Psychedelic Drug Intoxication in an
Evaluating Hallucinogenic or Psychedelic Drug Intoxication in an

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What are Hallucinogens?

...  Hallucinogenic substances are characterized by their ability to cause changes in a person’s perception of reality.  Persons using these drugs often report seeing images, hearing sounds, and feeling sensations that seem real, but do not exist.  In the past, plants and fungi that contained halluci ...
Sedative–hypnotic and Anxiolytic Drugs
Sedative–hypnotic and Anxiolytic Drugs

... first member of this group, chlordiazepoxide, was introduced, many congeners have been marketed. Most of these drugs possess anxiolytic, sedative–hypnotic, and anticonvulsant properties. Thus, the clinical indications for specific benzodiazepines are not absolute. and their ...
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Psychology

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new nerve cells for the adult brain
new nerve cells for the adult brain

... reside, albeit dormantly, in additional locations. Hence, the adult brain, which repairs itself so poorly, might actually harbor great potential for neuronal regeneration. If investigators can learn how to induce existing stem cells to produce useful numbers of functional nerve cells in chosen parts ...
Drugs with antimuscarinic effects
Drugs with antimuscarinic effects

Alzheimer`s Disease: Review Questions
Alzheimer`s Disease: Review Questions

... The temporal lobe, frontal lobe, and hippocampus are the areas most involved with cortical loss in Alzheimer’s disease. Major association areas are also involved with notable cortical atrophy. Relatively spared areas include the motor and sensory cortex as well as the visual cortex. 2. (E) All of th ...
ZAROXOLYN 5mg tablets ZAROXOLYN 10 mg tablets Metolazone
ZAROXOLYN 5mg tablets ZAROXOLYN 10 mg tablets Metolazone

... With overdose there is a risk of dehydration and electrolytic depletion. Treatment of overdose must target fluid reintegration and correction of the electrolytic imbalance. ...
the brain - Dr Magrann
the brain - Dr Magrann

...  Dopamine plays a major role in the brain system that is responsible for rewarddriven learning. Every type of reward that has been studied increases the level of dopamine transmission in the brain, and a variety of highly addictive drugs, including stimulants such as cocaine and methamphetamine, ac ...
Slide 1
Slide 1

... Process for understanding diagnosis • 6 months later: eligible for disease modifying drug trial ...
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Neuropsychopharmacology

Neuropsychopharmacology, an interdisciplinary science related to psychopharmacology (how drugs affect the mind) and fundamental neuroscience, is the study of the neural mechanisms that drugs act upon to influence behavior. It entails research of mechanisms of neuropathology, pharmacodynamics (drug action), psychiatric illness, and states of consciousness. These studies are instigated at the detailed level involving neurotransmission/receptor activity, bio-chemical processes, and neural circuitry. Neuropsychopharmacology supersedes psychopharmacology in the areas of ""how"" and ""why"", and additionally addresses other issues of brain function. Accordingly, the clinical aspect of the field includes psychiatric (psychoactive) as well as neurologic (non-psychoactive) pharmacology-based treatments.Developments in neuropsychopharmacology may directly impact the studies of anxiety disorders, affective disorders, psychotic disorders, degenerative disorders, eating behavior, and sleep behavior.The way fundamental processes of the brain are being discovered is creating a field on par with other “hard sciences” such as chemistry, biology, and physics, so that eventually it may be possible to repair mental illness with ultimate precision. An analogy can be drawn between the brain and an electronic device: neuropsychopharmacology is tantamount to revealing not only the schematic diagram, but the individual components, and every principle of their operation. The bank of amassed detail and complexity involved is huge; mere samples of some of the details are given in this article.
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