Information Sheet Nitrous Oxide
... canister into a whipped cream dispenser or a smaller gadget called a cracker. This has a balloon/ bag fitted to the release valve so that when the lever is pressed the balloon fills with gas which can then be inhaled6,7,8,9,10 (image 2 and 3). Serious damage could be done to the lungs if the gas was ...
... canister into a whipped cream dispenser or a smaller gadget called a cracker. This has a balloon/ bag fitted to the release valve so that when the lever is pressed the balloon fills with gas which can then be inhaled6,7,8,9,10 (image 2 and 3). Serious damage could be done to the lungs if the gas was ...
NIH Public Access
... Here, we investigated the role of α5* nAChRs in the reinforcing properties of nicotine. We found that wildtype and knockout mice responded for intravenously self-administered nicotine infusions according to an inverted U-shaped dose-response curve, consistent with previous reports in humans18, non-h ...
... Here, we investigated the role of α5* nAChRs in the reinforcing properties of nicotine. We found that wildtype and knockout mice responded for intravenously self-administered nicotine infusions according to an inverted U-shaped dose-response curve, consistent with previous reports in humans18, non-h ...
Characterisation of Plasmodium falciparum proteins expressed on
... vaccine available for malaria and available antimalarial drugs are often compromised by rapidly developing drug resistance. Therefore there is an urgent need to identify novel drug targets for the treatment of severe malaria and to explore therapeutic agents that can be used as adjuncts to the curre ...
... vaccine available for malaria and available antimalarial drugs are often compromised by rapidly developing drug resistance. Therefore there is an urgent need to identify novel drug targets for the treatment of severe malaria and to explore therapeutic agents that can be used as adjuncts to the curre ...
Deshpande_Gopikrishna_200708_phd
... Next, we expand the scope of functional connectivity to include directional interactions in the brain, which is termed effective connectivity. We investigate both linear and nonlinear Granger models of effective connectivity. First, we demonstrate the utility of an integrated approach involving mul ...
... Next, we expand the scope of functional connectivity to include directional interactions in the brain, which is termed effective connectivity. We investigate both linear and nonlinear Granger models of effective connectivity. First, we demonstrate the utility of an integrated approach involving mul ...
Searching for Arthur Koestler`s Holons – a systemstheoretical
... concern the degree of arborisation of a holarchy and the degree of reticulation of such a structure. Further he discusses the importance of regulation channels, which take care that in a holarchy signals are transmitted only one step at a time, up or down. The holons of a SOHOstructure have to be ba ...
... concern the degree of arborisation of a holarchy and the degree of reticulation of such a structure. Further he discusses the importance of regulation channels, which take care that in a holarchy signals are transmitted only one step at a time, up or down. The holons of a SOHOstructure have to be ba ...
A Review on Evidence Based Practice of Ginkgo biloba in Brain
... examination of ways that GB can be used most effectively as an adjunctive therapy, so that treatment effects are ...
... examination of ways that GB can be used most effectively as an adjunctive therapy, so that treatment effects are ...
Document
... absorbed in small intestine. Crosses all barriers Absorbed more slowly from cold beverages Less than 2% is excreted ...
... absorbed in small intestine. Crosses all barriers Absorbed more slowly from cold beverages Less than 2% is excreted ...
Autism: A Review of Biological Bases, Assessment, and
... the presynaptic end of a tether between two cells during synapse development (Graf, Zhang, Jin, Linhoff, & Craig, 2005). SHANK3 is a scaffolding protein that assists in dendrite growth and positioning within excitatory synapses (Roussignol et al., 2005). Disruptions in the formation or transportatio ...
... the presynaptic end of a tether between two cells during synapse development (Graf, Zhang, Jin, Linhoff, & Craig, 2005). SHANK3 is a scaffolding protein that assists in dendrite growth and positioning within excitatory synapses (Roussignol et al., 2005). Disruptions in the formation or transportatio ...
Descending motor pathways and the spinal
... pathways of the motor system originating in the forebrain, knowledge about the anatomy and function of the structures in the more caudally located parts of the central nervous system is indispensable. In this paper an overview will be presented of these caudal structures in brainstem and spinal cord ...
... pathways of the motor system originating in the forebrain, knowledge about the anatomy and function of the structures in the more caudally located parts of the central nervous system is indispensable. In this paper an overview will be presented of these caudal structures in brainstem and spinal cord ...
Full Text Article - European Journal of Biomedical and
... considered to be spinal reflex, but could also involved higher neural structures at this method identify mainly central analgesic.[17] The extracts derived from Michelia champaca flower buds M extract exhibited analgesic activity in albino rats by inhibiting acetic acid induce writhing, which is a m ...
... considered to be spinal reflex, but could also involved higher neural structures at this method identify mainly central analgesic.[17] The extracts derived from Michelia champaca flower buds M extract exhibited analgesic activity in albino rats by inhibiting acetic acid induce writhing, which is a m ...
Antimicrobial Pharmacokinetics and Pharmacodynamics
... antimicrobial agent. In some circumstances, protein binding can have a detrimental effect, whereas in others it may enhance dosing efficacy. The antimicrobial activity of a drug is inversely related to the extent of protein binding. Protein binding of antimicrobials in serum can interfere with biolo ...
... antimicrobial agent. In some circumstances, protein binding can have a detrimental effect, whereas in others it may enhance dosing efficacy. The antimicrobial activity of a drug is inversely related to the extent of protein binding. Protein binding of antimicrobials in serum can interfere with biolo ...
Intravenous Ondansetron as Antiemetic Prophylaxis for
... antagonists, for the treatment of postoperative and radiotherapy-induced nausea and vomiting. The effect of the drug comes from its influence on the peripheral and central nervous system. It acts by blocking serotonin receptors in the chemoreceptor trigger zone, thereby suppressing vagus nerve stimu ...
... antagonists, for the treatment of postoperative and radiotherapy-induced nausea and vomiting. The effect of the drug comes from its influence on the peripheral and central nervous system. It acts by blocking serotonin receptors in the chemoreceptor trigger zone, thereby suppressing vagus nerve stimu ...
Marijuana: Respiratory Tract Effects
... (endocannabinoids) has accelerated research on the cannabinoid receptor system. The first endocannabinoid was identified in 1992 and was named “anandamide” after the Sanskrit word for “bliss” [52]. Next, 2-arachidonylglyerol was discovered in 1995 [53, 54]. Finally, in 2001, 2-arachiodonyl glycerol ...
... (endocannabinoids) has accelerated research on the cannabinoid receptor system. The first endocannabinoid was identified in 1992 and was named “anandamide” after the Sanskrit word for “bliss” [52]. Next, 2-arachidonylglyerol was discovered in 1995 [53, 54]. Finally, in 2001, 2-arachiodonyl glycerol ...
Effects of Acute and Neurotoxic Exposure in the Rat
... suggest that that MDMA may induce cognitive (or behavioral) impairment in humans (1,16,19), as do extrapolations from animal studies (8,11). No one has previously examined whether the drug interferes with the initial acquisition of operant behavior, but such an effect would be significant in human u ...
... suggest that that MDMA may induce cognitive (or behavioral) impairment in humans (1,16,19), as do extrapolations from animal studies (8,11). No one has previously examined whether the drug interferes with the initial acquisition of operant behavior, but such an effect would be significant in human u ...
73737373 - Restless Legs Syndrome Foundation
... restless leg syndrome (RLS) (disease duration 18 +/15 years) • pin-prick pain ratings abnormal in RLS (static hyperalgesia) – Day and night ...
... restless leg syndrome (RLS) (disease duration 18 +/15 years) • pin-prick pain ratings abnormal in RLS (static hyperalgesia) – Day and night ...
Anatomical variations of septum pellucidum
... interpositi (CVI). They occur with a prevalence of 0.14%8-10. It is important to highlight that these cavities are in direct contact with the subarachnoid space, but they do not communicate with or are considered part of the ventricular system. As these cavities are not lined with ependyma or choroi ...
... interpositi (CVI). They occur with a prevalence of 0.14%8-10. It is important to highlight that these cavities are in direct contact with the subarachnoid space, but they do not communicate with or are considered part of the ventricular system. As these cavities are not lined with ependyma or choroi ...
Amphetamine-induced release of dopamine from the substantia
... and the brains quickly removed. The substantia nigra was dissected bilaterally by knife cuts made just caudal to the mammillary bodies, just rostral to the pons, lateral to the interpeduncular nucleus, and along a line extending through the medial lemniscus to the lateral edge of the brain stem vent ...
... and the brains quickly removed. The substantia nigra was dissected bilaterally by knife cuts made just caudal to the mammillary bodies, just rostral to the pons, lateral to the interpeduncular nucleus, and along a line extending through the medial lemniscus to the lateral edge of the brain stem vent ...
19 Improving the Oral Absorption of S-SEDDS Formulations
... SEDDS and S-SEDDS are self-emulsifying formulations of poorly soluble drugs that contain both a surfactant and lipid, along with a co-solvent, and they are usually formulated in gelatin capsules. Dilution of SEDDS or S-SEDDS formulations with water results in the generation of a microemulsion with a ...
... SEDDS and S-SEDDS are self-emulsifying formulations of poorly soluble drugs that contain both a surfactant and lipid, along with a co-solvent, and they are usually formulated in gelatin capsules. Dilution of SEDDS or S-SEDDS formulations with water results in the generation of a microemulsion with a ...
Modelling Neuronal Mechanisms of the Processing of Tones and System
... studied across the dimension of time at multiple scales, AS allows us to encompass in our study not only neuronal processing at the millisecond scale, but also slower mechanisms requiring from tens of milliseconds to over a second to have an effect. In short, we can incorporate great detail while no ...
... studied across the dimension of time at multiple scales, AS allows us to encompass in our study not only neuronal processing at the millisecond scale, but also slower mechanisms requiring from tens of milliseconds to over a second to have an effect. In short, we can incorporate great detail while no ...
K. Lutz, M. Widmer
... work revealed that unexpected presentation of a reward, acting as an unconditioned stimulus, leads to a phasic increase in dopaminergic activity in the substantia nigra/ventral tegmental area. After classical conditioning of such a reward to a conditioned stimulus, the conditioned stimulus elicits a ...
... work revealed that unexpected presentation of a reward, acting as an unconditioned stimulus, leads to a phasic increase in dopaminergic activity in the substantia nigra/ventral tegmental area. After classical conditioning of such a reward to a conditioned stimulus, the conditioned stimulus elicits a ...
Loss of MECP2 leads to telomere dysfunction and
... In comparing multiple lines of cells, it is clear from our data that loss of MECP2 leads to ...
... In comparing multiple lines of cells, it is clear from our data that loss of MECP2 leads to ...
The effects of bleomycin, mitomycin C, and in vitro in vivo
... Physiology) from Medunsa. She obtained a masters degree in Physiology in 2002 from the University of Pretoria, where she currently holds a lectureship position. Her thesis is entitled The effects of bleomycin, mitomycin C, and cytoskeletaldisrupting drugs on angiogenesis in vitro and haemangioma dev ...
... Physiology) from Medunsa. She obtained a masters degree in Physiology in 2002 from the University of Pretoria, where she currently holds a lectureship position. Her thesis is entitled The effects of bleomycin, mitomycin C, and cytoskeletaldisrupting drugs on angiogenesis in vitro and haemangioma dev ...
Altered fear learning across development in both mouse and human
... has been postulated to mediate extinction learning and may determine the efficacy of exposure therapy often used as part of cognitive behavioral therapy, it is important to discern how changes in the development of prefrontal circuitry influences fear extinction. Studying the development of fear learn ...
... has been postulated to mediate extinction learning and may determine the efficacy of exposure therapy often used as part of cognitive behavioral therapy, it is important to discern how changes in the development of prefrontal circuitry influences fear extinction. Studying the development of fear learn ...
Full Text - AIMS Press
... to non-target cells.[23,34] For example, during the treatment with estrogen, the distribution of the drug ...
... to non-target cells.[23,34] For example, during the treatment with estrogen, the distribution of the drug ...