Morphological Analysis of Dendritic Spine Development in Primary
... We have developedtissueculture conditions (Segaland Manor, 1992)in which we cangrow central neuronsfor severalweeks and monitor changesin their dendritesand dendritic spinesvia confocal microscopy. Electron microscopy was used to verify that the structures seenat the light level did indeed have the ...
... We have developedtissueculture conditions (Segaland Manor, 1992)in which we cangrow central neuronsfor severalweeks and monitor changesin their dendritesand dendritic spinesvia confocal microscopy. Electron microscopy was used to verify that the structures seenat the light level did indeed have the ...
senate report 103-97
... drugs intended for mind-control or behavior modification, often without their knowledge or consent. Although the ultimate goal of those experiments was to provide information that would help U.S. military and intelligence efforts, most Americans would agree that the use of soldiers as unwitting guin ...
... drugs intended for mind-control or behavior modification, often without their knowledge or consent. Although the ultimate goal of those experiments was to provide information that would help U.S. military and intelligence efforts, most Americans would agree that the use of soldiers as unwitting guin ...
ASD v3.0 - Nucleic Acids Research
... ASD) has been developed to provide comprehensive information featuring allosteric regulation. With increasing data, fundamental questions pertaining to allostery are currently receiving more attention from the mechanism of allosteric changes in an individual protein to the entire effect of the chang ...
... ASD) has been developed to provide comprehensive information featuring allosteric regulation. With increasing data, fundamental questions pertaining to allostery are currently receiving more attention from the mechanism of allosteric changes in an individual protein to the entire effect of the chang ...
Document
... BIN1 is the second most significant Alzheimer’s disease (AD) risk factor gene identified through genome-wide association studies. BIN1 is an adaptor protein that can bind to several proteins including c-Myc, clathrin, adaptor protein-2 and dynamin. BIN1 is widely expressed in the brain and periphera ...
... BIN1 is the second most significant Alzheimer’s disease (AD) risk factor gene identified through genome-wide association studies. BIN1 is an adaptor protein that can bind to several proteins including c-Myc, clathrin, adaptor protein-2 and dynamin. BIN1 is widely expressed in the brain and periphera ...
Daily Telegraph - Medicines for Malaria Venture
... disease has been overshadowed. The World Health Organisation (WHO) estimates that 38 million people worldwide were living with HIV in 2003; almost three million were killed by Aids the same year. Malaria, in contrast, is reckoned to have caused the deaths of a million people last year. It is the num ...
... disease has been overshadowed. The World Health Organisation (WHO) estimates that 38 million people worldwide were living with HIV in 2003; almost three million were killed by Aids the same year. Malaria, in contrast, is reckoned to have caused the deaths of a million people last year. It is the num ...
Ectopic sensory neurons in mutant cockroaches
... the chance of impaling the more proximally located filiform hair neuron cell body. Preparations were left for 4 hours at room temperature in a humid atmosphere. After removing the distal two cercal segments, dorsal cuticle and gut, the preparation was treated with ammonium sulphide, washed thoroughl ...
... the chance of impaling the more proximally located filiform hair neuron cell body. Preparations were left for 4 hours at room temperature in a humid atmosphere. After removing the distal two cercal segments, dorsal cuticle and gut, the preparation was treated with ammonium sulphide, washed thoroughl ...
Mastic Gum Kills Helicobacter pylori
... The H. pylori strains NCTC 11637 (a standard reference strain) and six fresh clinical isolates (three were sensitive and three were resistant to metronidazole) were maintained by passage on 7 percent horse chocolate blood agar or in IsoSensitest broth (with 5 percent fetal-calf serum) at 37°C in a m ...
... The H. pylori strains NCTC 11637 (a standard reference strain) and six fresh clinical isolates (three were sensitive and three were resistant to metronidazole) were maintained by passage on 7 percent horse chocolate blood agar or in IsoSensitest broth (with 5 percent fetal-calf serum) at 37°C in a m ...
5-HT1A Receptor Null Mutant Mice Responding Under a Differential
... were coming from a two-day interval in which training had been interrupted; in addition, on Mondays, the animals also had been subjected to non-standard food restriction, which sometimes resulted in a slightly less stable behavior then those recorded on the following four weekdays. (2) Injections we ...
... were coming from a two-day interval in which training had been interrupted; in addition, on Mondays, the animals also had been subjected to non-standard food restriction, which sometimes resulted in a slightly less stable behavior then those recorded on the following four weekdays. (2) Injections we ...
in vitro in vivo The effect of peroxisome proliferator- activated receptor-
... Peroxisome proliferator-activated receptors (PPARs) are ligand-activated nuclear hormone receptors involved in cellular differentiation, metabolism and development. There are three PPAR subtypes (a, b and c), which show distinct tissue distribution [1]. PPAR-c is activated by endogenous agonists inc ...
... Peroxisome proliferator-activated receptors (PPARs) are ligand-activated nuclear hormone receptors involved in cellular differentiation, metabolism and development. There are three PPAR subtypes (a, b and c), which show distinct tissue distribution [1]. PPAR-c is activated by endogenous agonists inc ...
The Structure of Pairwise Correlation in Mouse Primary Visual
... Introduction Throughout sensory systems, neurons are organized by response preference, so that like-responding neurons are close to each other, creating a functional map [e.g., orientation pinwheels in primary visual cortex (V1)]. Despite the ubiquity of maps, their role is unclear. For example, alt ...
... Introduction Throughout sensory systems, neurons are organized by response preference, so that like-responding neurons are close to each other, creating a functional map [e.g., orientation pinwheels in primary visual cortex (V1)]. Despite the ubiquity of maps, their role is unclear. For example, alt ...
Region-specific requirement for cholesterol
... Previous efforts to understand the role of cholesterol modification concluded that the cholesterol moiety is required for long-range spreading and signaling in the mouse limb buds (Lewis et al., 2001). Accordingly, it has been proposed that cholesterol modification is required for the formation of S ...
... Previous efforts to understand the role of cholesterol modification concluded that the cholesterol moiety is required for long-range spreading and signaling in the mouse limb buds (Lewis et al., 2001). Accordingly, it has been proposed that cholesterol modification is required for the formation of S ...
TIMOPTIC® in OCUDOSE
... ophthalmic solution) can usually be detected within one-half hour after a single dose. The maximum effect usually occurs in one to two hours and significant lowering of intraocular pressure can be maintained for periods as long as 24 hours with a single dose. Repeated observations over a period of o ...
... ophthalmic solution) can usually be detected within one-half hour after a single dose. The maximum effect usually occurs in one to two hours and significant lowering of intraocular pressure can be maintained for periods as long as 24 hours with a single dose. Repeated observations over a period of o ...
KINETIC STUDY OF ACAMPROSATE ABSORPTION IN RAT SMALL
... (Received 25 October 1999; in revised form 3 February 2000; accepted 10 February 2000) Abstract — Acamprosate (calcium bis acetyl-homotaurine), a homotaurine derivative, a structural analogue of γ-aminobutyric acid (GABA) and an upper homologue of taurine, is a relatively new drug used to prevent re ...
... (Received 25 October 1999; in revised form 3 February 2000; accepted 10 February 2000) Abstract — Acamprosate (calcium bis acetyl-homotaurine), a homotaurine derivative, a structural analogue of γ-aminobutyric acid (GABA) and an upper homologue of taurine, is a relatively new drug used to prevent re ...
Prepared By - Beckman Coulter
... The factors that can influence the relationship between the phenobarbital serum or plasma concentrations and clinical response include the type and severity of seizures, age, general state of health, and use of other drugs. The concentration of phenobarbital in serum or plasma depends on the time of ...
... The factors that can influence the relationship between the phenobarbital serum or plasma concentrations and clinical response include the type and severity of seizures, age, general state of health, and use of other drugs. The concentration of phenobarbital in serum or plasma depends on the time of ...
CURRICULUM VITAE - Test - University of South Florida
... This collaborative project brings together researchers in five states to simulate populations of respiratory neurons with realistic biophysical properties and computationally efficient large-scale simulations. Simulations are being used to integrate current knowledge, provide a framework to test and ...
... This collaborative project brings together researchers in five states to simulate populations of respiratory neurons with realistic biophysical properties and computationally efficient large-scale simulations. Simulations are being used to integrate current knowledge, provide a framework to test and ...
Selective attention through selective neuronal synchronization
... local field potential (LFP). The LFP reflects the summed transmembrane currents of neurons within few hundred micrometers of tissue. Since synchronized currents sum up much more efficiently than unsynchronized currents, the LFP reflects primarily synchronized synaptic activity. Changes in LFP power ...
... local field potential (LFP). The LFP reflects the summed transmembrane currents of neurons within few hundred micrometers of tissue. Since synchronized currents sum up much more efficiently than unsynchronized currents, the LFP reflects primarily synchronized synaptic activity. Changes in LFP power ...
Opioid Handout - Oral Surgery Albuquerque NM
... – That patients who do not have the genetic vulnerability or live in an environment that predisposes them to substance abuse may be ...
... – That patients who do not have the genetic vulnerability or live in an environment that predisposes them to substance abuse may be ...
alcohol consumption habits and sleep quality
... be aroused by sensory or other stimuli. Sleep can be divided into two types: 1. Slow-wave sleep 2. REM sleep (sleep with rapid eye movements). The function of sleep is not well understood, although a lot of evidence shows that sleep deprivation can have serious consequences, including increased risk ...
... be aroused by sensory or other stimuli. Sleep can be divided into two types: 1. Slow-wave sleep 2. REM sleep (sleep with rapid eye movements). The function of sleep is not well understood, although a lot of evidence shows that sleep deprivation can have serious consequences, including increased risk ...
Fiber Tracking using Magnetic Resonance Diffusion Tensor Imaging
... From a basic neuroscience perspective, it provides the unique ability to determine in vivo both function and connectivity within the brain. Many applications, from the basic science interest of how brain processes for example visual information (Werring et al., 1999) to the applied science interest ...
... From a basic neuroscience perspective, it provides the unique ability to determine in vivo both function and connectivity within the brain. Many applications, from the basic science interest of how brain processes for example visual information (Werring et al., 1999) to the applied science interest ...
Atarax™
... • As a sedative used as premedication • As symptomatic relief in atopic pruritus The effectiveness of hydroxyzine as an antianxiety agent for long term use, that is more than 4 months, has not been assessed by systematic clinical studies. The physician should reassess periodically the usefulness of ...
... • As a sedative used as premedication • As symptomatic relief in atopic pruritus The effectiveness of hydroxyzine as an antianxiety agent for long term use, that is more than 4 months, has not been assessed by systematic clinical studies. The physician should reassess periodically the usefulness of ...
Effect of chest wall vibration on the canine diaphragm during breathing
... during inspiration results in an increased parasternal intercostal inspiratory activity, and that vibration of the lower portion of the ribcage induces an increased activity in the caudal internal intercostal muscles. Conversely, recent studies in dogs have shown that when the upper ribcage is vibra ...
... during inspiration results in an increased parasternal intercostal inspiratory activity, and that vibration of the lower portion of the ribcage induces an increased activity in the caudal internal intercostal muscles. Conversely, recent studies in dogs have shown that when the upper ribcage is vibra ...
Coupling Data Mining and Laboratory Experiments to Discover Drug
... RESULTS Both direct and indirect signals in the adverse event reports provided evidence that the combination of ceftriaxone (a cephalosporin antibiotic) and lansoprazole (a proton-pump inhibitor) will prolong the QT interval. In the EHR, we found that patients taking both ceftriaxone and lansoprazol ...
... RESULTS Both direct and indirect signals in the adverse event reports provided evidence that the combination of ceftriaxone (a cephalosporin antibiotic) and lansoprazole (a proton-pump inhibitor) will prolong the QT interval. In the EHR, we found that patients taking both ceftriaxone and lansoprazol ...
new zealand data sheet
... Published juvenile animal studies demonstrate that the administration of anaesthetic and sedative agents that block NMDA receptors and/or potentiate GABA activity increase neuronal apoptosis in the developing brain and result in long-term cognitive defects when used for longer than 3 hours. The clin ...
... Published juvenile animal studies demonstrate that the administration of anaesthetic and sedative agents that block NMDA receptors and/or potentiate GABA activity increase neuronal apoptosis in the developing brain and result in long-term cognitive defects when used for longer than 3 hours. The clin ...
Effects on upper gastrointestinal motility
... paresis a single oral dose of domperidone 40 mg significantly stimulated gastric emptying of both liquids and solids (65). After long-term administration (35-51 days) of 20 mg t.i.d. by the oral route, the drug was still significantly effective or liquid emptying, but no longer capable of enhancing ...
... paresis a single oral dose of domperidone 40 mg significantly stimulated gastric emptying of both liquids and solids (65). After long-term administration (35-51 days) of 20 mg t.i.d. by the oral route, the drug was still significantly effective or liquid emptying, but no longer capable of enhancing ...
rna interference for improving the outcome of islet
... (PEG-PBC) micelles. Embelin loaded PEG-PCD micelles showed significant inhibition of C4-2 prostate cancer cell proliferation, while no obvious cellular toxicity was observed for blank micelles. In Chapter 7, we studied the use of paclitaxel and lapatinib loaded lipopolymer micelles for treating MDR ...
... (PEG-PBC) micelles. Embelin loaded PEG-PCD micelles showed significant inhibition of C4-2 prostate cancer cell proliferation, while no obvious cellular toxicity was observed for blank micelles. In Chapter 7, we studied the use of paclitaxel and lapatinib loaded lipopolymer micelles for treating MDR ...