Anatomy of Olivocochlear Neurons
... Both groups of OC neurons have fibers that branch extensively in the cochlea (Fig. 2.3). The end result of the branching is that a relatively small number of OC neurons gives rise to numerous synapses in the cochlea. LOC fibers synapse mainly on dendrites of auditory nerve fibers beneath IHCs. In th ...
... Both groups of OC neurons have fibers that branch extensively in the cochlea (Fig. 2.3). The end result of the branching is that a relatively small number of OC neurons gives rise to numerous synapses in the cochlea. LOC fibers synapse mainly on dendrites of auditory nerve fibers beneath IHCs. In th ...
Cholecystokinin Modulates Migration of
... GnRH-1 neurons, increasing the distance that the cells migrated. GnRH-1 neuronal migration in mice carrying a genetic deletion of either CCK-1R or CCK-2R receptor genes was also analyzed. At embryonic day 14.5, the total number of GnRH-1 cells was identical in wild-type and mutant mice; however, the ...
... GnRH-1 neurons, increasing the distance that the cells migrated. GnRH-1 neuronal migration in mice carrying a genetic deletion of either CCK-1R or CCK-2R receptor genes was also analyzed. At embryonic day 14.5, the total number of GnRH-1 cells was identical in wild-type and mutant mice; however, the ...
Psilocybin links binocular rivalry switch rate to attention and
... ketanserin blocked the majority of psilocybin’s “positive” psychosis-like hallucinogenic symptoms. However, ketanserin had no influence on either the psilocybin-induced slowing of binocular rivalry or the drug’s “negative-type symptoms” associated with reduced arousal and vigilance. Conclusions Toge ...
... ketanserin blocked the majority of psilocybin’s “positive” psychosis-like hallucinogenic symptoms. However, ketanserin had no influence on either the psilocybin-induced slowing of binocular rivalry or the drug’s “negative-type symptoms” associated with reduced arousal and vigilance. Conclusions Toge ...
CIELAP – There is No "AWAY" - Canadian Institute for
... medical practice; however, this document focuses only on environment-related efforts. These include surveillance, education, and reductions in antibiotic use in animals, particularly for growth promotion and prophylactic uses, and in restricting products used in human therapy. For EDSs, the problem ...
... medical practice; however, this document focuses only on environment-related efforts. These include surveillance, education, and reductions in antibiotic use in animals, particularly for growth promotion and prophylactic uses, and in restricting products used in human therapy. For EDSs, the problem ...
Diuretic agents Diuretic A "diuretic" is an agent that increases urine
... Due to the large NaCl absorptive capacity of this segment , loop diuretics are among the most efficacious diuretic agents available. Mechanism of action . These drugs inhibit the luminal Na+/K+/2Cl- co-transporter in the thick ascending limb of Henle's loop. By inhibiting this transporter, the loop ...
... Due to the large NaCl absorptive capacity of this segment , loop diuretics are among the most efficacious diuretic agents available. Mechanism of action . These drugs inhibit the luminal Na+/K+/2Cl- co-transporter in the thick ascending limb of Henle's loop. By inhibiting this transporter, the loop ...
Drug Therapy Management Series: Psychiatric Disorders
... relative to TCAs. However, gastrointestinal problems (nausea, vomiting, and anorexia), male and female sexual dysfunction, and weight loss are more common. In overdose, SSRIs can cause serotonin syndrome, which is characterized by myoclonus, diarrhea, confusion, psychomotor agitation, hyperreflexia, ...
... relative to TCAs. However, gastrointestinal problems (nausea, vomiting, and anorexia), male and female sexual dysfunction, and weight loss are more common. In overdose, SSRIs can cause serotonin syndrome, which is characterized by myoclonus, diarrhea, confusion, psychomotor agitation, hyperreflexia, ...
Combination Chemotherapy in Cancer: Principles, Evaluation and
... drug interactions. Information obtained from clinical protocols is valuable, but is timeconsuming, expensive and does not provide data on the biochemical and molecular mechanisms of drug interaction at cellular level resulted from combined treatments (Zoli et al., 2001). It is very difficult to dete ...
... drug interactions. Information obtained from clinical protocols is valuable, but is timeconsuming, expensive and does not provide data on the biochemical and molecular mechanisms of drug interaction at cellular level resulted from combined treatments (Zoli et al., 2001). It is very difficult to dete ...
(Full text - MSWord file 171K)
... functioning which build on the strong resemblance between dopamine neuron activity and the temporal difference prediction error signal in the critic, and between dopamine-dependent long-term synaptic plasticity in the striatum and learning guided by a prediction error signal in the actor. We selecti ...
... functioning which build on the strong resemblance between dopamine neuron activity and the temporal difference prediction error signal in the critic, and between dopamine-dependent long-term synaptic plasticity in the striatum and learning guided by a prediction error signal in the actor. We selecti ...
Anatomy and Physiology
... energy sources (e.g. TTP, CTP, GTP, UTP) could be salvaged in an emergency to recharge ADP As shown above, the nucleoside triphosphate (NTP) which are the remaining energy molecules of TTP, CTP, GTP, UTP could be utilized to recharge ADP by transferring its high energy bond Nucleoside diphosphokinas ...
... energy sources (e.g. TTP, CTP, GTP, UTP) could be salvaged in an emergency to recharge ADP As shown above, the nucleoside triphosphate (NTP) which are the remaining energy molecules of TTP, CTP, GTP, UTP could be utilized to recharge ADP by transferring its high energy bond Nucleoside diphosphokinas ...
Page 1
... • Drug effects are related to [Drug] • [Drug] in the circulation or biophase is related ...
... • Drug effects are related to [Drug] • [Drug] in the circulation or biophase is related ...
- Wiley Online Library
... parasites con¢ned to the mucosa, poor absorption may enhance rather than diminish e¤cacy. However, caution must be exercised when comparing the metabolism of di¡erent drugs in rats and mice where such di¡erences could be related more to animal than structural di¡erences of the compounds [16]. The pa ...
... parasites con¢ned to the mucosa, poor absorption may enhance rather than diminish e¤cacy. However, caution must be exercised when comparing the metabolism of di¡erent drugs in rats and mice where such di¡erences could be related more to animal than structural di¡erences of the compounds [16]. The pa ...
Selective cognitive dysfunction in acetylcholine M
... and their corresponding genes, termed M1–M5, have been identified and cloned, but their high degree of sequence similarity has hindered the development of highly selective ligands1. Therefore, the broad array of deficits produced by antagonists such as scopolamine or atropine and more selective liga ...
... and their corresponding genes, termed M1–M5, have been identified and cloned, but their high degree of sequence similarity has hindered the development of highly selective ligands1. Therefore, the broad array of deficits produced by antagonists such as scopolamine or atropine and more selective liga ...
Prediction error for free monetary reward in the human prefrontal
... Studies in both humans and nonhuman primates have shown that frontostriatal circuits are important for mediating the influence of reward expectation on the selection and preparation of actions. Specific dopamine-rich regions within the prefrontal cortex (Goldman-Rakic et al., 1992; Lidow et al., 199 ...
... Studies in both humans and nonhuman primates have shown that frontostriatal circuits are important for mediating the influence of reward expectation on the selection and preparation of actions. Specific dopamine-rich regions within the prefrontal cortex (Goldman-Rakic et al., 1992; Lidow et al., 199 ...
The substituted amphetamines 3,4
... may produce neurotoxicity via the same mechanism. A common feature of MDMA, methamphetamine, PCA and fenfluramine is that they cause the release of 5-HT from presynaptie terminals (Wong et al., 1973; Schmidt and Gibb, 1985; Nichols et al., 1982; Buczko et al., 1975). This release is blocked by 5-HT ...
... may produce neurotoxicity via the same mechanism. A common feature of MDMA, methamphetamine, PCA and fenfluramine is that they cause the release of 5-HT from presynaptie terminals (Wong et al., 1973; Schmidt and Gibb, 1985; Nichols et al., 1982; Buczko et al., 1975). This release is blocked by 5-HT ...
The Evolution of Neuron Types and Cortical
... the axonal cytoskeleton, its expression is associated with neurons that have thick myelinated axons (Hoffman et al., 1987; Kirkcaldie et al., 2002). In addition, the calcium-binding proteins–calbindin D28k (CB), calretinin (CR), and parvalbumin (PV)– are useful markers for understanding the cortical ...
... the axonal cytoskeleton, its expression is associated with neurons that have thick myelinated axons (Hoffman et al., 1987; Kirkcaldie et al., 2002). In addition, the calcium-binding proteins–calbindin D28k (CB), calretinin (CR), and parvalbumin (PV)– are useful markers for understanding the cortical ...
Toxicities of Drugs Used in the Management of Fever
... Although aspirin and acetaminophen have been used medically for a century, and acetaminophen has been available as a nonprescription drug since 1960, the past decade has seen the transition of nonsteroidal anti-inflammatory drugs (NSAIDs) ibuprofen, naproxen and ketoprofen from prescription-only to ...
... Although aspirin and acetaminophen have been used medically for a century, and acetaminophen has been available as a nonprescription drug since 1960, the past decade has seen the transition of nonsteroidal anti-inflammatory drugs (NSAIDs) ibuprofen, naproxen and ketoprofen from prescription-only to ...
Optimizing antifungal choice and administration
... most likely to provide success for a patient with an IFI. When the species has not yet been identified, an analysis of regional epidemiology and risk factors can provide clues as to the most likely pathogen. For severely immunocompromised patients, a fungicidal agent may be preferred over a fungista ...
... most likely to provide success for a patient with an IFI. When the species has not yet been identified, an analysis of regional epidemiology and risk factors can provide clues as to the most likely pathogen. For severely immunocompromised patients, a fungicidal agent may be preferred over a fungista ...
A Small World of Neuronal Synchrony
... called ‘‘small-world’’ properties. A small-world network exhibits a connectivity that constitutes a compromise between random and nearest neighbor regimes resulting in a short average path length despite the predominance of local connections (Watts and Strogatz 1998; Sporns et al. 2004; Bassett and ...
... called ‘‘small-world’’ properties. A small-world network exhibits a connectivity that constitutes a compromise between random and nearest neighbor regimes resulting in a short average path length despite the predominance of local connections (Watts and Strogatz 1998; Sporns et al. 2004; Bassett and ...
Drug - Cicbaa.com
... It is important to underline the frequency of severe reactions to paracetamol (5%). Their mechanism seems to be complex : one reaction was due to an IgE mechanism and in three cases, the allergy check-up was negative and the diagnosis could be established only by oral challenge tests positive to lo ...
... It is important to underline the frequency of severe reactions to paracetamol (5%). Their mechanism seems to be complex : one reaction was due to an IgE mechanism and in three cases, the allergy check-up was negative and the diagnosis could be established only by oral challenge tests positive to lo ...
Reflexes - Sinoe Medical Association
... quadriceps and starts the reflex action – The quadriceps contract and the antagonistic ...
... quadriceps and starts the reflex action – The quadriceps contract and the antagonistic ...
rajiv gandhi university of health sciences, bangalore
... tingling sensation of scalp, pruritis, diaphoresis, orthostatic hypotension, bronchospasm and dyspnea. Raheem I A, et al compared oral nifedipine versus intravenous labetalol for acute blood pressure control in hypertensive emergencies of pregnancy and concluded that oral nifedipine and intravenous ...
... tingling sensation of scalp, pruritis, diaphoresis, orthostatic hypotension, bronchospasm and dyspnea. Raheem I A, et al compared oral nifedipine versus intravenous labetalol for acute blood pressure control in hypertensive emergencies of pregnancy and concluded that oral nifedipine and intravenous ...
PDF Document
... pain (61–63), this approach to neuromodulation fails in many patients for reasons that are incompletely understood. This remains true even after a half-century (64) of clinical and basic science research and derives in part from the nonselective nature of electrical stimulation (58). Similarly, alth ...
... pain (61–63), this approach to neuromodulation fails in many patients for reasons that are incompletely understood. This remains true even after a half-century (64) of clinical and basic science research and derives in part from the nonselective nature of electrical stimulation (58). Similarly, alth ...
The Case for Personalized Medicine
... treated with Ziagen® (abacavir) can experience multi-organ system hypersensitivity to the drug, which in some cases can be fatal. This adverse reaction is strongly associated with the The U.S. Food and Drug Administration HLA-B*5701 gene, easily identified through (FDA) has approved the Amplichip® g ...
... treated with Ziagen® (abacavir) can experience multi-organ system hypersensitivity to the drug, which in some cases can be fatal. This adverse reaction is strongly associated with the The U.S. Food and Drug Administration HLA-B*5701 gene, easily identified through (FDA) has approved the Amplichip® g ...