The Control of Seizure-Like Activity in the Rat Hippocampal Slice
... et al., 1991; Lehnertz and Elger, 1995; Elger and Lehnertz, 1998; Lopes da Silva and Pijn, 1999). State transitions from interictal to ictal events have been inferred from the geometrical properties of the attractors reconstructed from the original voltage recordings, specifically from correlation d ...
... et al., 1991; Lehnertz and Elger, 1995; Elger and Lehnertz, 1998; Lopes da Silva and Pijn, 1999). State transitions from interictal to ictal events have been inferred from the geometrical properties of the attractors reconstructed from the original voltage recordings, specifically from correlation d ...
Determinants of the Sensitivity of Human Small
... were the first to demonstrate that acute rises in intracellular MTX binding capacity could be a determinant ofdrug resistance in patients with acute leukemia. More recently it has been shown that in vivo resistance after MTX treatment may be due to DHFR gene amplification and elevated target enzyme ...
... were the first to demonstrate that acute rises in intracellular MTX binding capacity could be a determinant ofdrug resistance in patients with acute leukemia. More recently it has been shown that in vivo resistance after MTX treatment may be due to DHFR gene amplification and elevated target enzyme ...
Temperature - Division Of Animal Sciences
... (C.B. Transfer of heat from the core volumes by passive conduction through muscle and skin and into the environment complete the concept, with the addition of evaporative heat losses from the skin and head core). A complete anatomical model of man has not been developed, but the problem is not simpl ...
... (C.B. Transfer of heat from the core volumes by passive conduction through muscle and skin and into the environment complete the concept, with the addition of evaporative heat losses from the skin and head core). A complete anatomical model of man has not been developed, but the problem is not simpl ...
Urinary Incontinence in Adults
... dizziness, fatigue, difficulty in micturition (less commonly urinary retention), palpitation, and skin reactions (including dry skin, rash, and photosensitivity); also headache, diarrhoea, angioedema, arrhythmias, and tachycardia. Central nervous system stimulation, such as restlessness, disorientat ...
... dizziness, fatigue, difficulty in micturition (less commonly urinary retention), palpitation, and skin reactions (including dry skin, rash, and photosensitivity); also headache, diarrhoea, angioedema, arrhythmias, and tachycardia. Central nervous system stimulation, such as restlessness, disorientat ...
Hold your horses: A dynamic computational role
... The details of the BG model are described in Frank (2005a, 2005b). In brief, the premotor cortex represents and “considers” two possible responses (R1 and R2) for each input stimulus. The BG system modulates which one of these responses is facilitated and which is suppressed by signaling Go or NoGo ...
... The details of the BG model are described in Frank (2005a, 2005b). In brief, the premotor cortex represents and “considers” two possible responses (R1 and R2) for each input stimulus. The BG system modulates which one of these responses is facilitated and which is suppressed by signaling Go or NoGo ...
408 3 Physiology and Anatomy for the Speed and Power
... and skin all create electric fields as a result of the piezoelectric effect. These signals are not byproducts, but are communications that inform neighboring cells of what’s happening in different parts of the body. In the same way that proprioception works within the nervous system, the same commun ...
... and skin all create electric fields as a result of the piezoelectric effect. These signals are not byproducts, but are communications that inform neighboring cells of what’s happening in different parts of the body. In the same way that proprioception works within the nervous system, the same commun ...
Increased responses in trigeminocervical nociceptive neurons to cervical input after
... nociceptive in¯ow from the meningies to the brain (Hoskin et al., 1996; Strassman et al., 1996; Bove and Moskowitz, 1997). This innervation is considered to be the peripheral substrate of head pain in primary headache syndromes, such as migraine or cluster headache (Goadsby, 2001). Primary nocicepti ...
... nociceptive in¯ow from the meningies to the brain (Hoskin et al., 1996; Strassman et al., 1996; Bove and Moskowitz, 1997). This innervation is considered to be the peripheral substrate of head pain in primary headache syndromes, such as migraine or cluster headache (Goadsby, 2001). Primary nocicepti ...
Porges and Carter (2010). Neurobiology and
... circuit is used first in response to challenges to the organism. If the newest circuit fails to provide safety, older survival-oriented circuits are recruited sequentially, with the defensive fight-or-flight response preceding the use of an immobilization response. It is important to note that socia ...
... circuit is used first in response to challenges to the organism. If the newest circuit fails to provide safety, older survival-oriented circuits are recruited sequentially, with the defensive fight-or-flight response preceding the use of an immobilization response. It is important to note that socia ...
DRUGS ACTING ON THE SKIN AND MUCOUS MEMBRANES
... application without friction to inflamed unbroken skin. They cool by evaporation of solvents, require frequent application, and may leave a thin film of drug on the skin (not easily calamine lotion). Lotions are used in hairy areas and for lesions with minor exudation and ulceration. Care must be ta ...
... application without friction to inflamed unbroken skin. They cool by evaporation of solvents, require frequent application, and may leave a thin film of drug on the skin (not easily calamine lotion). Lotions are used in hairy areas and for lesions with minor exudation and ulceration. Care must be ta ...
22_LectureSlides
... • Feed-forward control-predictive – Response anticipates stimulus – More timely, but depends on practice ...
... • Feed-forward control-predictive – Response anticipates stimulus – More timely, but depends on practice ...
Electroencephalography
... • Analysing induced activity that isn’t phase-locked, i.e. that would be averaged out with conventional eventrelated analysis • Characterising and understanding typical responses to specific events – e.g. significant increase in gamma band activity 20-60 ms following an auditory stimulus ...
... • Analysing induced activity that isn’t phase-locked, i.e. that would be averaged out with conventional eventrelated analysis • Characterising and understanding typical responses to specific events – e.g. significant increase in gamma band activity 20-60 ms following an auditory stimulus ...
pharmaceutical factors
... assortment of medications and analytical normative document) must correspond and high level of pharmacotherapy. From this point of view presently efficiency is estimated not only on an amount but also in quality treatments by medicinal preparations. It means, it is necessary to estimate, as far as t ...
... assortment of medications and analytical normative document) must correspond and high level of pharmacotherapy. From this point of view presently efficiency is estimated not only on an amount but also in quality treatments by medicinal preparations. It means, it is necessary to estimate, as far as t ...
Beta-lactam antibiotics
... Cephalosporins - what to remember Developed in response to clinical needs Grouped by “generation” Learn properties of a prototype from each generation Extremely widely used - ...
... Cephalosporins - what to remember Developed in response to clinical needs Grouped by “generation” Learn properties of a prototype from each generation Extremely widely used - ...
creutzfeldt-jakob disease
... 10%-15% and 1% of human prion diseases, respectively. The genetic form of disease results from different mutations in the coding region of the PRNP located at the short arm of chromosome 20. All of the mutations are inherited in an autosomal dominant pattern. Depending on the mutation, the inherited ...
... 10%-15% and 1% of human prion diseases, respectively. The genetic form of disease results from different mutations in the coding region of the PRNP located at the short arm of chromosome 20. All of the mutations are inherited in an autosomal dominant pattern. Depending on the mutation, the inherited ...
1 Diosynth Biotechnology – Riding the Biomanufacturing Wave
... While Diosynth Biotechnology has the strong financial backing of Akzo Nobel in these expansions, there is no denying the fact that capital investment in an industry of the same nature as pharmaceuticals and drugs is often fraught with uncertainty. Diosynth could find itself plagued by the problems ...
... While Diosynth Biotechnology has the strong financial backing of Akzo Nobel in these expansions, there is no denying the fact that capital investment in an industry of the same nature as pharmaceuticals and drugs is often fraught with uncertainty. Diosynth could find itself plagued by the problems ...
Might stimulant drugs support moral agency in ADHD children? Steven Edward Hyman
... Prior to their first morning dose, children are free of the stimulant effect and thus exhibit ADHD symptoms. In addition, as described by a subject in this study,2 children take occasional drug holidays with the agreement of their parents, for example, because they do not like taking pills, are troub ...
... Prior to their first morning dose, children are free of the stimulant effect and thus exhibit ADHD symptoms. In addition, as described by a subject in this study,2 children take occasional drug holidays with the agreement of their parents, for example, because they do not like taking pills, are troub ...
Synergistic interactions of SQ109, a new
... area from no effect to antagonistic. By applying simple algebra as published and validated elsewhere,9 we can evaluate the potential outcome of two drugs in combination in an in vitro assay system. To determine the optimal drug combination(s) that might include SQ109 in future human efficacy trials, ...
... area from no effect to antagonistic. By applying simple algebra as published and validated elsewhere,9 we can evaluate the potential outcome of two drugs in combination in an in vitro assay system. To determine the optimal drug combination(s) that might include SQ109 in future human efficacy trials, ...
The DEA`s War on Doctors - Association of American Physicians and
... There is an historical parallel with the DEA’s current prosecution of medical doctors in its war on drugs. Before World War I, narcotics were legal and widely used to relieve pain and treat illness. The public was unaware of the addictive potential of these drugs. For example, morphine was commonly ...
... There is an historical parallel with the DEA’s current prosecution of medical doctors in its war on drugs. Before World War I, narcotics were legal and widely used to relieve pain and treat illness. The public was unaware of the addictive potential of these drugs. For example, morphine was commonly ...
Chapter 9 lesson 1 - ROP Pharmacology for Health Care
... Understanding Pharmacology for Health Professionals, 5th Ed. Susan M. Turley ...
... Understanding Pharmacology for Health Professionals, 5th Ed. Susan M. Turley ...
Rich-club organization in effective connectivity among cortical neurons
... were killed after the recording session; and brain tissue was sectioned, immunostained for NeuN, and imaged to verify the silicon prong placement. Signals from all recording sites were simultaneously sampled at 25 kHz. Spike sorting was performed off-line using a semi-automated Matlab script. The da ...
... were killed after the recording session; and brain tissue was sectioned, immunostained for NeuN, and imaged to verify the silicon prong placement. Signals from all recording sites were simultaneously sampled at 25 kHz. Spike sorting was performed off-line using a semi-automated Matlab script. The da ...
Basics Pharmacology Review
... Assistant Professor, Dept of Family Medicine, University of Ottawa Clinical Pharmacist, Bruyere Academic Family Health Team March 2013 [email protected] (Partially adapted from slides by Marc Riachi, R.Ph.) ...
... Assistant Professor, Dept of Family Medicine, University of Ottawa Clinical Pharmacist, Bruyere Academic Family Health Team March 2013 [email protected] (Partially adapted from slides by Marc Riachi, R.Ph.) ...
Major R&D Pipeline
... ・From the results of the Phase III trial in non-small cell lung cancer, the submission target of FY 2014 has been revised and further development strategy is currently under consideration. ...
... ・From the results of the Phase III trial in non-small cell lung cancer, the submission target of FY 2014 has been revised and further development strategy is currently under consideration. ...
Articles in PresS. J Neurophysiol (March 20, 2003). 10.1152/jn
... In addition to a detailed analysis of the generic features of the membrane model in high and low dopamine conditions, we provide a simulation of responses to target presentation in the memory guided saccade task used by Kawagoe and colleagues (1998). This simulation demonstrates one specific instanc ...
... In addition to a detailed analysis of the generic features of the membrane model in high and low dopamine conditions, we provide a simulation of responses to target presentation in the memory guided saccade task used by Kawagoe and colleagues (1998). This simulation demonstrates one specific instanc ...
A comparision of Hodgkin-Huxley and soliton neural theories
... demonstrated that this net current could be separated into two distinct components, a fast inward current carried by Na+ ions, and a more slowly activating outward current carried by K+ ions. Using ingenious voltage-clamp protocols, they concluded that these two currents result from independent perm ...
... demonstrated that this net current could be separated into two distinct components, a fast inward current carried by Na+ ions, and a more slowly activating outward current carried by K+ ions. Using ingenious voltage-clamp protocols, they concluded that these two currents result from independent perm ...
Typical Neural Representations of Action Verbs
... actions: When deciding whether hand actions involve a tool, lMTG activity is high in individuals that have never seen (i.e., congenitally blind adults) (Noppeney et al. 2003). These data suggest that visual--motion experience is not necessary for the lMTG to be engaged in action concepts. Somewhat s ...
... actions: When deciding whether hand actions involve a tool, lMTG activity is high in individuals that have never seen (i.e., congenitally blind adults) (Noppeney et al. 2003). These data suggest that visual--motion experience is not necessary for the lMTG to be engaged in action concepts. Somewhat s ...