Original article The protease inhibitors ritonavir and saquinavir
... reduced levels of adipogenic transcription factors [24] and reduced messenger RNA expression of adiponectin and leptin [25], all of which indicate that apoptotic mechanisms are increased in the fat tissue during HAART [26]. Indeed, increased adipocyte apoptosis Antiviral Therapy 15.2 ...
... reduced levels of adipogenic transcription factors [24] and reduced messenger RNA expression of adiponectin and leptin [25], all of which indicate that apoptotic mechanisms are increased in the fat tissue during HAART [26]. Indeed, increased adipocyte apoptosis Antiviral Therapy 15.2 ...
It`s a Cruciate Rupture: Now What?
... term cruciate which means to cross) and both the CCL and the CdCL play a partial role in preventing rotation of the stifle. Pathophysiology CCL rupture is typically considered to be degenerative in nature and often bilateral. In fact 33-50% of dogs that present with a unilateral lameness will have b ...
... term cruciate which means to cross) and both the CCL and the CdCL play a partial role in preventing rotation of the stifle. Pathophysiology CCL rupture is typically considered to be degenerative in nature and often bilateral. In fact 33-50% of dogs that present with a unilateral lameness will have b ...
Epilepsy: A Comprehensive Study
... limited by the relationship of brain regions to activate those regions that they are synaptically coupled to. ...
... limited by the relationship of brain regions to activate those regions that they are synaptically coupled to. ...
Hyperlipidemia - Hana Alharbi
... Fibric Acid Derivatives: PPAR Activators Clofibrate as well as two other fibrates, gemfibrozil and fenofibrate. Mechanism of Action The mechanisms by which fibrates lower lipoprotein levels, or raise HDL levels, remain unclear. Recent studies suggest that many of the effects of these compounds on bl ...
... Fibric Acid Derivatives: PPAR Activators Clofibrate as well as two other fibrates, gemfibrozil and fenofibrate. Mechanism of Action The mechanisms by which fibrates lower lipoprotein levels, or raise HDL levels, remain unclear. Recent studies suggest that many of the effects of these compounds on bl ...
Experimental Study of Nephroprotective Properties of Sodium Poly
... An article describes results of antihypoxant drug sodium poly-(2,5-dihydroxsyphenilen)-4-thiosulfate acid effects on filtrationexcretory renal function in experimental renal insufficiency. Use of sodium poly-(2,5-dyhidroksyfenilen)-4-thiosulfate acid 90 mg/kg increases diuresis in rats, reduces endo ...
... An article describes results of antihypoxant drug sodium poly-(2,5-dihydroxsyphenilen)-4-thiosulfate acid effects on filtrationexcretory renal function in experimental renal insufficiency. Use of sodium poly-(2,5-dyhidroksyfenilen)-4-thiosulfate acid 90 mg/kg increases diuresis in rats, reduces endo ...
GHB: An Important Pharmacologic and Clinical Update
... GHB is a chemical compound structurally similar to the inhibitory brain neurotransmitter GABA. Its proposed function is as an inhibitory neuromodulator within the central nervous system, affecting the function of other neurotransmitters in the dopaminergic and gabaergic systems.2 Physiologic and pha ...
... GHB is a chemical compound structurally similar to the inhibitory brain neurotransmitter GABA. Its proposed function is as an inhibitory neuromodulator within the central nervous system, affecting the function of other neurotransmitters in the dopaminergic and gabaergic systems.2 Physiologic and pha ...
Complications of Antiretroviral Therapy
... fat enlargement (buffalo hump), peripheral wasting, facial wasting, breast enlargement, and cushingoid appearance, has been observed in patients receiving antiretroviral therapy. The mechanism and long-term consequences of these events are currently unknown. A causal relationship has not been establ ...
... fat enlargement (buffalo hump), peripheral wasting, facial wasting, breast enlargement, and cushingoid appearance, has been observed in patients receiving antiretroviral therapy. The mechanism and long-term consequences of these events are currently unknown. A causal relationship has not been establ ...
The Effects of Brain Drain on Haiti - DRUM
... Some individual factors that affect why people migrate are whether they should migrate, their financial ability to migrate and whether a person is prepared and content with living away from home, while country or communal factors that affect why people migrate are support or social networks. Some di ...
... Some individual factors that affect why people migrate are whether they should migrate, their financial ability to migrate and whether a person is prepared and content with living away from home, while country or communal factors that affect why people migrate are support or social networks. Some di ...
CCN Exercise Sheet 1: Encoding, Decoding and Sensory Adaptation
... • Implement the maximum likelihood decoder algorithm (Tip: matlab optimization functions such as f minsearch can be useful) and try it out on a few trials. • Plot the bias with this decoder before adaptation. • In which sense is this decoder more ‘optimal’ ? If you were to quantify it, how would you ...
... • Implement the maximum likelihood decoder algorithm (Tip: matlab optimization functions such as f minsearch can be useful) and try it out on a few trials. • Plot the bias with this decoder before adaptation. • In which sense is this decoder more ‘optimal’ ? If you were to quantify it, how would you ...
Stem Cell Therapeutics. Singrec et al. 2008 Stem Cells Vol 1 pp. 313-328.
... the developmental potential of EC cells is remarkable, they are still clearly cancer cells and their growth and differentiation is difficult to control. In 1981, two hallmark papers reported the successful derivation of pluripotent embryonic ESCs from the inner cell mass of blastocyst-stage mouse emb ...
... the developmental potential of EC cells is remarkable, they are still clearly cancer cells and their growth and differentiation is difficult to control. In 1981, two hallmark papers reported the successful derivation of pluripotent embryonic ESCs from the inner cell mass of blastocyst-stage mouse emb ...
Synapse Formation in the Absence of Cell Bodies Requires Protein
... varicosities contacting the major processes of L7 contain release sites (one to three active zones per varicosity). SN varicosities do not contain release sites when contacting the substrate or target neuron L11, which fail to respond to action potential activity in the SN (Glanzman et al., 1989). N ...
... varicosities contacting the major processes of L7 contain release sites (one to three active zones per varicosity). SN varicosities do not contain release sites when contacting the substrate or target neuron L11, which fail to respond to action potential activity in the SN (Glanzman et al., 1989). N ...
Replication of scrapie and BSE prions in mites.
... Bovine Spongiform Encephalopathy (BSE) in cattle and Creutzfeldt-Jacob Disease (CJD) in humans. The infectious agents associated with all of these diseases are believed to be Prions ("proteinaceous infectious particles"), also known as PrP. The proteins are related to endogenous membrane proteins in ...
... Bovine Spongiform Encephalopathy (BSE) in cattle and Creutzfeldt-Jacob Disease (CJD) in humans. The infectious agents associated with all of these diseases are believed to be Prions ("proteinaceous infectious particles"), also known as PrP. The proteins are related to endogenous membrane proteins in ...
EUGENE GARFIELD
... Ap[ysia, he had worked on the mammalian hippocampus (a curved elongated ridge that extends over the floor of the descending horn of each lateral ventricle of the brain and consists of gray matter covered on the ventricular surface with white matter). This effort resulted in a four-part study publish ...
... Ap[ysia, he had worked on the mammalian hippocampus (a curved elongated ridge that extends over the floor of the descending horn of each lateral ventricle of the brain and consists of gray matter covered on the ventricular surface with white matter). This effort resulted in a four-part study publish ...
In vivo imaging of dopamine and serotonin release Udo de
... Mamo 2003; Leenders 2002; Naranjo et al. 2001; Volkow et al. 2002a). The involvement of dopamine (DA) in these disorders may be related to its function in reward processing (Kapur 2003; Kunig et al. 2000; Schmidt et al. 2001). However, the exact role of DA in these processes is not completely known ...
... Mamo 2003; Leenders 2002; Naranjo et al. 2001; Volkow et al. 2002a). The involvement of dopamine (DA) in these disorders may be related to its function in reward processing (Kapur 2003; Kunig et al. 2000; Schmidt et al. 2001). However, the exact role of DA in these processes is not completely known ...
Current Management of Basal Cell Carcinoma, Part 3
... surgical) methods cannot be used, 5-fluorouracil (5-FU) is a chemotherapeutic agent that inhibits DNA synthesis, thus pre- ...
... surgical) methods cannot be used, 5-fluorouracil (5-FU) is a chemotherapeutic agent that inhibits DNA synthesis, thus pre- ...
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
... Abstract: Traditional medicines are most commonly used to meet the health care needs especially in developing countries. Gynura cusimba (D.Don) Moore has been traditionally used as a medicinal plant for healing wounds, headache and as anti-ulcer for centuries. The present study was taken to evaluate ...
... Abstract: Traditional medicines are most commonly used to meet the health care needs especially in developing countries. Gynura cusimba (D.Don) Moore has been traditionally used as a medicinal plant for healing wounds, headache and as anti-ulcer for centuries. The present study was taken to evaluate ...
PDF
... mature NGF (mNGF) on SCG neurites, but not on trigeminal ganglion neurites, to promote profuse growth and branching at the stage in development when the axons of these neurons are branching extensively in their target tissues. This growth-promoting effect of proNGF on sympathetic neurites becomes ev ...
... mature NGF (mNGF) on SCG neurites, but not on trigeminal ganglion neurites, to promote profuse growth and branching at the stage in development when the axons of these neurons are branching extensively in their target tissues. This growth-promoting effect of proNGF on sympathetic neurites becomes ev ...
Neural Correlates of Human Virtue Judgment
... population from which data are obtained. The contrast images were obtained from single-subject analysis and entered into the group analysis. A 1-sample t-test was applied to determine group activation for each effect. We used SPM’s small volume correction to correct for multiple testing in regions a ...
... population from which data are obtained. The contrast images were obtained from single-subject analysis and entered into the group analysis. A 1-sample t-test was applied to determine group activation for each effect. We used SPM’s small volume correction to correct for multiple testing in regions a ...
Kennedy, Peter G.E. (2004) Human African trypanosomiasis of the
... The key issue in HAT diagnosis and therapeutic decision making is to distinguish reliably the late encephalitic stage of HAT from the early stage. Accurate staging of HAT is critical because failure to treat a patient with CNS involvement will lead inevitably to death from the disease, yet inappropr ...
... The key issue in HAT diagnosis and therapeutic decision making is to distinguish reliably the late encephalitic stage of HAT from the early stage. Accurate staging of HAT is critical because failure to treat a patient with CNS involvement will lead inevitably to death from the disease, yet inappropr ...
JAMES ALAN MURRAY, PhD - California State University, East Bay
... sea slug Tritonia diomedea. Jones A, Murray JA, Cain SD, Wyeth R (Poster) (5)Eighth International Congress of Neuroethology [Vancouver, BC; July 2007]. Structure and distribution of putative ciliated receptors on the oral veil of Tritonia diomedea. Yadlapalli K, Murray JA (Poster) (6)Society for Int ...
... sea slug Tritonia diomedea. Jones A, Murray JA, Cain SD, Wyeth R (Poster) (5)Eighth International Congress of Neuroethology [Vancouver, BC; July 2007]. Structure and distribution of putative ciliated receptors on the oral veil of Tritonia diomedea. Yadlapalli K, Murray JA (Poster) (6)Society for Int ...
Context-induced relapse to drug seeking: a review
... in the presence of the CS is lesser than the probability that the US will occur in the absence of the CS (Rescorla 1969). Occasion setter. In Pavlovian conditioning, occasion setter cues signal whether another conditioned cue (CS) is to be reinforced or not reinforced. In contrast to traditional exc ...
... in the presence of the CS is lesser than the probability that the US will occur in the absence of the CS (Rescorla 1969). Occasion setter. In Pavlovian conditioning, occasion setter cues signal whether another conditioned cue (CS) is to be reinforced or not reinforced. In contrast to traditional exc ...
full text - TReAD Lab
... have distinct – and possibly opposed – functions. As a part of the indirect basal ganglia pathway, the NAcc-VP input may be important for the initiation of goal-directed behaviors. It may also be critical for learning new associations and actions, given the strong influence of the ventral subiculum ...
... have distinct – and possibly opposed – functions. As a part of the indirect basal ganglia pathway, the NAcc-VP input may be important for the initiation of goal-directed behaviors. It may also be critical for learning new associations and actions, given the strong influence of the ventral subiculum ...
Original article Pill burden in HIV infection: 20 years of experience
... ARV-experienced patients who are older than 45 years of age have higher mean daily pill burdens than patients ≤45 years of age. From 1990 to 1996 the difference was minimal but has since widened as shown in Table 3. On average, older patients take two or three pills more per day mainly due to the us ...
... ARV-experienced patients who are older than 45 years of age have higher mean daily pill burdens than patients ≤45 years of age. From 1990 to 1996 the difference was minimal but has since widened as shown in Table 3. On average, older patients take two or three pills more per day mainly due to the us ...
BMP4 expression in the adult rat brain
... growth factor β (TGF- β) superfamily and plays important roles in multiple biological events. Although BMP4 expression has been well described in the early development of central nervous system (CNS), little information is available for its expression in the adult CNS. We, thus, investigated BMP4 ex ...
... growth factor β (TGF- β) superfamily and plays important roles in multiple biological events. Although BMP4 expression has been well described in the early development of central nervous system (CNS), little information is available for its expression in the adult CNS. We, thus, investigated BMP4 ex ...
How do mammalian mitochondria synthesize proteins?
... The initiation of mitochondrial translation differs significantly from that found in bacteria and the eukaryotic cytoplasm, as the mitochondrial mRNAs are not capped and essentially have no upstream leader sequences to facilitate ribosome binding [6]. How mitoribosomes are directed to the initiation ...
... The initiation of mitochondrial translation differs significantly from that found in bacteria and the eukaryotic cytoplasm, as the mitochondrial mRNAs are not capped and essentially have no upstream leader sequences to facilitate ribosome binding [6]. How mitoribosomes are directed to the initiation ...