Intrinsic Cellular Properties and Connectivity Density Determine
... Computational studies of networks of biophysical neuron models have played a large role in identifying the mechanisms by which inhibitory interneurons generate rhythmic firing amongst themselves and in synaptically connected excitatory pyramidal cells. Previous studies on the rhythmic properties of ...
... Computational studies of networks of biophysical neuron models have played a large role in identifying the mechanisms by which inhibitory interneurons generate rhythmic firing amongst themselves and in synaptically connected excitatory pyramidal cells. Previous studies on the rhythmic properties of ...
The Expanding Role of Microsomal Enzyme Induction, and Its
... enzyme induction are drugs and xenobiotics. Factors modulating the extent of enzyme induction by a given agent include age and nutrition, and wide species variations are encountered with different inducing agents. Markers for microsomal enzyme induction include determination of the plasma half-life ...
... enzyme induction are drugs and xenobiotics. Factors modulating the extent of enzyme induction by a given agent include age and nutrition, and wide species variations are encountered with different inducing agents. Markers for microsomal enzyme induction include determination of the plasma half-life ...
the concept of the therapeutic window in the choice of h1
... Wheal and flare studies have been widely used to indicate in vivo differences in the potential efficacy of secondgeneration antihistamines.8-11 Frossard et al recently compared the inhibition of histamine-induced wheal and flare by fexofenadine HCl 180 mg, loratadine 10 mg, and desloratadine 5 mg in ...
... Wheal and flare studies have been widely used to indicate in vivo differences in the potential efficacy of secondgeneration antihistamines.8-11 Frossard et al recently compared the inhibition of histamine-induced wheal and flare by fexofenadine HCl 180 mg, loratadine 10 mg, and desloratadine 5 mg in ...
Development - Publications Repository
... SEMA3F being expressed in r3 and r5 and NRP2 being expressed by the r2-derived (trigeminal) and r4-derived (hyoid) neural crest cells (Gammill et al., 2007; Eickholt et al., 1999). Moreover, cranial neural crest cells travel through the normally crest-free zone at r3 level when semaphorin function i ...
... SEMA3F being expressed in r3 and r5 and NRP2 being expressed by the r2-derived (trigeminal) and r4-derived (hyoid) neural crest cells (Gammill et al., 2007; Eickholt et al., 1999). Moreover, cranial neural crest cells travel through the normally crest-free zone at r3 level when semaphorin function i ...
Thrombin = anticoagulant
... Head-to-head comparison between anti-IIa and anti-Xa inhibitors Even if we have a study which shows that the cost-benefit ratio is superior with one compound versus another one, this will be true : ...
... Head-to-head comparison between anti-IIa and anti-Xa inhibitors Even if we have a study which shows that the cost-benefit ratio is superior with one compound versus another one, this will be true : ...
IOSR Journal of Agriculture and Veterinary Science (IOSR-JAVS)
... the active ingredient(s) were not isolated. However, previous reports indicate that a number of tropical plants contain constituents that have been demonstrated to be clinically efficacious against many protozoal diseases [11]. Similarly, it is known that existing trypanocidal drugs exert their ther ...
... the active ingredient(s) were not isolated. However, previous reports indicate that a number of tropical plants contain constituents that have been demonstrated to be clinically efficacious against many protozoal diseases [11]. Similarly, it is known that existing trypanocidal drugs exert their ther ...
Changes in GABA Modulation During a Theta Cycle May Be
... potentials due to neuronal spiking activity changes during different phases of the theta rhythm (Rudell, Fox, & Rank, 1980; Buszaki, Grastyan, Czopf, Kellenyi, & Prohaska, 1981; Rudell & Fox, 1984). This could result from changes in presynaptic and/or postsynaptic inhibition during a theta cycle. Mo ...
... potentials due to neuronal spiking activity changes during different phases of the theta rhythm (Rudell, Fox, & Rank, 1980; Buszaki, Grastyan, Czopf, Kellenyi, & Prohaska, 1981; Rudell & Fox, 1984). This could result from changes in presynaptic and/or postsynaptic inhibition during a theta cycle. Mo ...
BETA ACTIVITY: A CARRIER FOR VISUAL ATTENTION
... excitability of cells activated by attended objects or voluntary action (Treisman and Gelade 1980, Crick 1994). The possibility exists that both mechanisms cooperate; the attentional mechanism may activate populations of cells thereby allowing them to synchronize their activity. In a hierarchically ...
... excitability of cells activated by attended objects or voluntary action (Treisman and Gelade 1980, Crick 1994). The possibility exists that both mechanisms cooperate; the attentional mechanism may activate populations of cells thereby allowing them to synchronize their activity. In a hierarchically ...
stockholm oncology summary report
... Karolinska Institutet is a part of the Cancer Core Europe Consortium that includes six of the most prominent cancer centers in Europe. It was formed in 2014 and focuses on the development of personalized cancer medicine. Cancer makes up more than 30 percent of the research volume at Karolinska Insti ...
... Karolinska Institutet is a part of the Cancer Core Europe Consortium that includes six of the most prominent cancer centers in Europe. It was formed in 2014 and focuses on the development of personalized cancer medicine. Cancer makes up more than 30 percent of the research volume at Karolinska Insti ...
Oral Drug Therapy Guidelines in Surgical Patients
... A patient may be ‘Nil-by-mouth’ for several reasons, e.g. non-functional gut, lack of swallowing reflex, patient unconscious or prior to surgery. Nausea or vomiting may also inhibit the use of oral medicines. Surgery is not an indication to stop the majority of medications a patient may be taking on ...
... A patient may be ‘Nil-by-mouth’ for several reasons, e.g. non-functional gut, lack of swallowing reflex, patient unconscious or prior to surgery. Nausea or vomiting may also inhibit the use of oral medicines. Surgery is not an indication to stop the majority of medications a patient may be taking on ...
Non-reward neural mechanisms in the orbitofrontal cortex
... Rolls, & Kischka, 2004), and even antisocial and psychopathic behaviour (Rolls, 2014). For these reasons, understanding the mechanisms that underlie non-reward is important not only for understanding normal human behaviour and how it changes when rewards are not received, but also for understanding ...
... Rolls, & Kischka, 2004), and even antisocial and psychopathic behaviour (Rolls, 2014). For these reasons, understanding the mechanisms that underlie non-reward is important not only for understanding normal human behaviour and how it changes when rewards are not received, but also for understanding ...
Annexure – II
... have been developed through traditional knowledge of herbs, which is a ray of hope for kidney failure patients3. A number of herbs traditionally used are Kalanchoe pinnata4, Benincasa cerifera5, Ocimum sanctum6, Phyllanthus niruri7, Passiflora foetida8, Hemidesmus indicus9 and Ficus racemosa10. Acti ...
... have been developed through traditional knowledge of herbs, which is a ray of hope for kidney failure patients3. A number of herbs traditionally used are Kalanchoe pinnata4, Benincasa cerifera5, Ocimum sanctum6, Phyllanthus niruri7, Passiflora foetida8, Hemidesmus indicus9 and Ficus racemosa10. Acti ...
Response Characteristics of Spinal Cord Dorsal Horn Neurons in
... Hao, Jing-Xia, Ron C. Kupers, and Xiao-Jun Xu. Response characteristics of spinal cord dorsal horn neurons in chronic allodynic rats after spinal cord injury. J Neurophysiol 92: 1391–1399, 2004; 10.1152/jn.00121.2004. The physiological mechanisms of chronic pain in patients with spinal cord injury ( ...
... Hao, Jing-Xia, Ron C. Kupers, and Xiao-Jun Xu. Response characteristics of spinal cord dorsal horn neurons in chronic allodynic rats after spinal cord injury. J Neurophysiol 92: 1391–1399, 2004; 10.1152/jn.00121.2004. The physiological mechanisms of chronic pain in patients with spinal cord injury ( ...
Chapter 14: Integration of Nervous System Functions
... In short-term memory, A) information is retained for less than a second. B) the frontal lobe plays the most important role. C) the limit to information stored is approximately 20 bits. D) when new information is presented, old information is eliminated. E) about 12 bits of information can be stored. ...
... In short-term memory, A) information is retained for less than a second. B) the frontal lobe plays the most important role. C) the limit to information stored is approximately 20 bits. D) when new information is presented, old information is eliminated. E) about 12 bits of information can be stored. ...
Network Self-Organization Explains the Statistics and
... The information processing abilities of neural circuits arise from their synaptic connection patterns. Understanding the laws governing these connectivity patterns is essential for understanding brain function. The overall distribution of synaptic strengths of local excitatory connections in cortex ...
... The information processing abilities of neural circuits arise from their synaptic connection patterns. Understanding the laws governing these connectivity patterns is essential for understanding brain function. The overall distribution of synaptic strengths of local excitatory connections in cortex ...
Distinct Representation and Distribution of Visual Information by
... Cell-type clustering. For cluster analysis, each data parameter was standardized by subtracting the population mean and dividing by the SD. Clustering was performed in p-dimensional space, where p is the number of parameters, without any previous dimensionality reduction. We used Euclidean distances ...
... Cell-type clustering. For cluster analysis, each data parameter was standardized by subtracting the population mean and dividing by the SD. Clustering was performed in p-dimensional space, where p is the number of parameters, without any previous dimensionality reduction. We used Euclidean distances ...
artificial neural networks
... Machine learning involves adaptive mechanisms that enable computers to learn from experience, learn by example and learn by analogy. Learning capabilities can improve the performance of an intelligent system over time. The most popular approaches to machine learning are artificial neural networks an ...
... Machine learning involves adaptive mechanisms that enable computers to learn from experience, learn by example and learn by analogy. Learning capabilities can improve the performance of an intelligent system over time. The most popular approaches to machine learning are artificial neural networks an ...
8129402
... Bell Thelphone Laboratories has studied numerous people and has helped to prove that eidetic imagery does exist. not just the product of a vivid childhood imagination. ...
... Bell Thelphone Laboratories has studied numerous people and has helped to prove that eidetic imagery does exist. not just the product of a vivid childhood imagination. ...
Associative memory properties of multiple cortical modules
... The modules are composed of a very large number of graded-response neurons with hyperbolic transfer functions. The form of the intra- and inter-modular connections reflects the result of Hebbian learning of sparsely coded binary patterns by the multi-modular network, and is essentially a generalizat ...
... The modules are composed of a very large number of graded-response neurons with hyperbolic transfer functions. The form of the intra- and inter-modular connections reflects the result of Hebbian learning of sparsely coded binary patterns by the multi-modular network, and is essentially a generalizat ...
Introduction to Pharmacology Chapter 1
... OxyContin is intended for use by terminal cancer patients and chronic pain sufferers. It has been linked to at least 120 overdose deaths nationwide. It has been alleged that Purdue Pharma L.P. has marketed the drug excessively without stressing its addictive nature. Doctors and pharmacists say the m ...
... OxyContin is intended for use by terminal cancer patients and chronic pain sufferers. It has been linked to at least 120 overdose deaths nationwide. It has been alleged that Purdue Pharma L.P. has marketed the drug excessively without stressing its addictive nature. Doctors and pharmacists say the m ...
The Emergence of Selective Attention through - laral
... the time increases with the number of distracters and the similarity between the visual features of the target and the distracters [1]. These results, originally used to sustain a serial deployment of a visual attention ‘spotlight’, have been later explained by a parallel interactive process. In par ...
... the time increases with the number of distracters and the similarity between the visual features of the target and the distracters [1]. These results, originally used to sustain a serial deployment of a visual attention ‘spotlight’, have been later explained by a parallel interactive process. In par ...
Circuits through prefrontal cortex, basal ganglia, and ventral anterior
... linkage of the basal ganglia with functionally distinct sectors of the prefrontal cortex, engaged in executive control and goal directed behavior (for review see Barbas, 2000a). The connections of the mediodorsal thalamic nucleus with the prefrontal cortex and the basal ganglia have been described i ...
... linkage of the basal ganglia with functionally distinct sectors of the prefrontal cortex, engaged in executive control and goal directed behavior (for review see Barbas, 2000a). The connections of the mediodorsal thalamic nucleus with the prefrontal cortex and the basal ganglia have been described i ...
Selective Brain to Blood Efflux Transport of para
... the exception of P-glycoprotein, only limited information is available regarding selective efflux transport at the BBB (Suzuki et al., 1996). Recently we developed a novel method, termed the “brain efflux index method,” to estimate directly the efflux rate of various substances at the BBB (Kakee et ...
... the exception of P-glycoprotein, only limited information is available regarding selective efflux transport at the BBB (Suzuki et al., 1996). Recently we developed a novel method, termed the “brain efflux index method,” to estimate directly the efflux rate of various substances at the BBB (Kakee et ...
PDF file - Via Medica Journals
... although QT measurement and its heart rate variation remain uneasy. The treatment of TdP immediate defibrillation for hemodynamic instability is based on heart rate acceleration by isoprenaline or cardiac pacing, potassium (if hypokalemic) and intravenous magnesium sulfate [5]. Other alternative or ...
... although QT measurement and its heart rate variation remain uneasy. The treatment of TdP immediate defibrillation for hemodynamic instability is based on heart rate acceleration by isoprenaline or cardiac pacing, potassium (if hypokalemic) and intravenous magnesium sulfate [5]. Other alternative or ...
Superior digit memory of abacus experts
... more efficient to mentally manipulate large numbers using a spatial representation than a sequentially organized phonological representation. It may be that these processes involve the bilateral frontal–parietal areas, which have important roles in visuo-motor processing [14]. Another possibility is ...
... more efficient to mentally manipulate large numbers using a spatial representation than a sequentially organized phonological representation. It may be that these processes involve the bilateral frontal–parietal areas, which have important roles in visuo-motor processing [14]. Another possibility is ...