Accepted version
... Multiple Sclerosis (MS) is the most common chronic inflammatory demyelinating neurodegenerative disease of the central nervous system (CNS) and the leading cause of nontraumatic neurological disability in young adults. The etiology of MS involves interplay between environmental factors and multiple ...
... Multiple Sclerosis (MS) is the most common chronic inflammatory demyelinating neurodegenerative disease of the central nervous system (CNS) and the leading cause of nontraumatic neurological disability in young adults. The etiology of MS involves interplay between environmental factors and multiple ...
Mediation and the Brain: The Neuropsychology of
... The Art of Peace does not rely on weapons or brute force to succeed; instead we put ourselves in tune with the universe, maintain peace in our own realms, nurture life, and prevent death and destruction. The true meaning of the term samurai is one who serves and adheres to the power of love.” ...
... The Art of Peace does not rely on weapons or brute force to succeed; instead we put ourselves in tune with the universe, maintain peace in our own realms, nurture life, and prevent death and destruction. The true meaning of the term samurai is one who serves and adheres to the power of love.” ...
Through the looking glass: counter
... et al., 2001; Keysers & Perrett, 2004). This hypothesis suggests that if an infant were unable to see her own actions and grew up in an environment where mirrors and imitating adults were replaced by systems that showed counter-mirror actions (e.g. foot movements when she moved her hands), then she ...
... et al., 2001; Keysers & Perrett, 2004). This hypothesis suggests that if an infant were unable to see her own actions and grew up in an environment where mirrors and imitating adults were replaced by systems that showed counter-mirror actions (e.g. foot movements when she moved her hands), then she ...
Medical issues about Methadone : What the counselor needs to know
... receptors. By blocking opioid receptors, the “reward” and acute reinforcing effects from dopamine are diminished, and opioid consumption is reduced. ...
... receptors. By blocking opioid receptors, the “reward” and acute reinforcing effects from dopamine are diminished, and opioid consumption is reduced. ...
Evolution of the Pallium in Birds and Reptiles
... The organization of the adult avian pallium has been well studied and that of reptiles somewhat studied. Based upon Nissl staining patterns of embryonic and adult brains, Ulinksi and others defined a general organization of the bird and reptile pallia [4]. This includes a dorsal part, called the dor ...
... The organization of the adult avian pallium has been well studied and that of reptiles somewhat studied. Based upon Nissl staining patterns of embryonic and adult brains, Ulinksi and others defined a general organization of the bird and reptile pallia [4]. This includes a dorsal part, called the dor ...
Smell, Taste, Texture, and Temperature
... Studies of the brain mechanisms involved in smell and taste are revealing some of the brain processing relevant to understanding how the brain interprets different odors and tastes. Direct study of the brain activations produced by odor and taste may reveal effects that are not reported verbally. It ...
... Studies of the brain mechanisms involved in smell and taste are revealing some of the brain processing relevant to understanding how the brain interprets different odors and tastes. Direct study of the brain activations produced by odor and taste may reveal effects that are not reported verbally. It ...
Toxicology Introduct..
... toxic effects on living organisms. In risk assessment, mechanistic data may be very useful in demonstrating that an adverse outcome observed in laboratory animals is or is not directly relevant to humans. Mechanistic data are also useful in the design and production of safer alternative chemicals an ...
... toxic effects on living organisms. In risk assessment, mechanistic data may be very useful in demonstrating that an adverse outcome observed in laboratory animals is or is not directly relevant to humans. Mechanistic data are also useful in the design and production of safer alternative chemicals an ...
Trillium Therapeutics Inc. (Form: 6-K, Received: 02
... In 2017, Trillium is also planning to advance its second SIRPaFc fusion protein, TTI-622, into clinical testing. TTI-622 contains an IgG4 Fc region and is thus anticipated to have a different pharmacologic profile and enable greater exposures in patients than TTI-621 (IgG1 Fc). Like TTI-621, TTI-622 ...
... In 2017, Trillium is also planning to advance its second SIRPaFc fusion protein, TTI-622, into clinical testing. TTI-622 contains an IgG4 Fc region and is thus anticipated to have a different pharmacologic profile and enable greater exposures in patients than TTI-621 (IgG1 Fc). Like TTI-621, TTI-622 ...
Respiratory Pharmacology Week 6
... does not replace fast-acting inhalers for sudden symptoms. Advair Diskus effectively treats the two main components of asthma at the same time: constriction, the tightening of the muscles around the airways, and inflammation, the swelling and irritation of the airways. Constriction and inflammation ...
... does not replace fast-acting inhalers for sudden symptoms. Advair Diskus effectively treats the two main components of asthma at the same time: constriction, the tightening of the muscles around the airways, and inflammation, the swelling and irritation of the airways. Constriction and inflammation ...
Current status of trans-platinum compounds in cancer therapy
... have been tested in preclinical evaluations and about 30 have entered human clinical trials [2], however, it is not totally unexpected since, in general, a new drug only arises from every 10 000 compounds tested. ...
... have been tested in preclinical evaluations and about 30 have entered human clinical trials [2], however, it is not totally unexpected since, in general, a new drug only arises from every 10 000 compounds tested. ...
Cln3 Targeted Disruption of the Gene Provides a Mouse Model for Batten Disease
... a compelling case can be made for the involvement of lysosomes. First, a key diagnostic feature of Batten disease is the intracellular accumulation of autofluorescent material within lysosomes. Stored material is present in neurons as well as in other cell types (Rapola, 1993; Goebel et al., 1999; L ...
... a compelling case can be made for the involvement of lysosomes. First, a key diagnostic feature of Batten disease is the intracellular accumulation of autofluorescent material within lysosomes. Stored material is present in neurons as well as in other cell types (Rapola, 1993; Goebel et al., 1999; L ...
Inferior Parietal Lobule Function in Spatial Perception and
... visual extinction. The most dramatic and consequently most studied deficit seen in these animals is their reluctance to use the contralateral limb in visually guided reaching, although they employ the limb appropriately in other tasks such as locomotion and climbing. When the contralateral limb is u ...
... visual extinction. The most dramatic and consequently most studied deficit seen in these animals is their reluctance to use the contralateral limb in visually guided reaching, although they employ the limb appropriately in other tasks such as locomotion and climbing. When the contralateral limb is u ...
Olfactory System Anatomy
... process that forms the fila olfactoria. The cilia provide the transduction surface for odorous stimuli. The vomeronasal organ is a specialized bilateral membranous structure located in the base of the anterior nasal septum, at the junction of the septal cartilage and the bony septum. It is believed ...
... process that forms the fila olfactoria. The cilia provide the transduction surface for odorous stimuli. The vomeronasal organ is a specialized bilateral membranous structure located in the base of the anterior nasal septum, at the junction of the septal cartilage and the bony septum. It is believed ...
Causes of Brain Damage
... neurotransmitter release – especially glutamate Blood-deprived neurons become overactive and release glutamate Glutamate overactivates its receptors, especially NMDA receptors leading to an influx of Na+ and Ca2+ Copyright © 2011 Pearson Education, Inc. All rights reserved. ...
... neurotransmitter release – especially glutamate Blood-deprived neurons become overactive and release glutamate Glutamate overactivates its receptors, especially NMDA receptors leading to an influx of Na+ and Ca2+ Copyright © 2011 Pearson Education, Inc. All rights reserved. ...
Nicotine excites hypothalamic arcuate anorexigenic
... Huang H, Xu Y, van den Pol AN. Nicotine excites hypothalamic arcuate anorexigenic proopiomelanocortin neurons and orexigenic neuropeptide Y neurons: similarities and differences. J Neurophysiol 106: 1191–1202, 2011. First published June 8, 2011; doi:10.1152/jn.00740.2010.—Two of the biggest health p ...
... Huang H, Xu Y, van den Pol AN. Nicotine excites hypothalamic arcuate anorexigenic proopiomelanocortin neurons and orexigenic neuropeptide Y neurons: similarities and differences. J Neurophysiol 106: 1191–1202, 2011. First published June 8, 2011; doi:10.1152/jn.00740.2010.—Two of the biggest health p ...
Poulet etal - Cornell University
... Fig. 5 Inhibitory inputs are present during fictive singing with all motor and sensory neurons cut. a PADs occur in auditory afferent neurons, b IPSPs occur in ON1 and low amplitude hyperpolarising potentials are present in c AN1 and d AN2 during the chirps. These inputs were therefore generated withi ...
... Fig. 5 Inhibitory inputs are present during fictive singing with all motor and sensory neurons cut. a PADs occur in auditory afferent neurons, b IPSPs occur in ON1 and low amplitude hyperpolarising potentials are present in c AN1 and d AN2 during the chirps. These inputs were therefore generated withi ...
Temporal coding in the gustatory system
... Intensity is another characteristic that is encoded by the taste system; in gustation, stimulus intensity is correlated with stimulus concentration. Most often, as the concentration of a taste stimulus increases so does the firing rate of the taste-responsive cell (Nakamura and Norgren, 1991; Nishijo ...
... Intensity is another characteristic that is encoded by the taste system; in gustation, stimulus intensity is correlated with stimulus concentration. Most often, as the concentration of a taste stimulus increases so does the firing rate of the taste-responsive cell (Nakamura and Norgren, 1991; Nishijo ...
Investigating Anatomical and Molecular Aspects of
... This thesis focuses on anatomical and molecular characterization of sensory afferents innervating these peripheral receptors. In many ways, PSNs are similar; however, there are key aspects in which they differ. We hypothesize that one major area of differences exists at the molecular level and thus ...
... This thesis focuses on anatomical and molecular characterization of sensory afferents innervating these peripheral receptors. In many ways, PSNs are similar; however, there are key aspects in which they differ. We hypothesize that one major area of differences exists at the molecular level and thus ...
Opioids - Waterloo Region Integrated Drugs Strategy
... Fentanyl is a potent opioid, used in anesthesia, for pain, chronic pain, pain in end of life care Typically administered as a patch placed on the skin Fentanyl is produced by pharmaceutical manufacturers Small chemical changes to fentanyl can result in drugs with very similar actions These “bootleg” ...
... Fentanyl is a potent opioid, used in anesthesia, for pain, chronic pain, pain in end of life care Typically administered as a patch placed on the skin Fentanyl is produced by pharmaceutical manufacturers Small chemical changes to fentanyl can result in drugs with very similar actions These “bootleg” ...
DENS 521 4th SF
... In healthy subjects, their half-lives range from 1 hour (cefotaxime) to between 6 and 8 hours (ceftriaxone) These antibiotics diffuse well into most tissues (e.g., cefotaxime and ceftriaxone Excretion is primarily renal Indications include suspected bacterial meningitis and treatment of hosp ...
... In healthy subjects, their half-lives range from 1 hour (cefotaxime) to between 6 and 8 hours (ceftriaxone) These antibiotics diffuse well into most tissues (e.g., cefotaxime and ceftriaxone Excretion is primarily renal Indications include suspected bacterial meningitis and treatment of hosp ...
Menopause drugs compared - Consumer Reports Health
... last up to four years, but millions of women experience symptoms for many years. Importantly, Table 1 also lists symptoms that were once thought to be linked to menopause but which recent studies indicate are not. Some of these symptoms – such as mood swings, depression, and reduced libido – could b ...
... last up to four years, but millions of women experience symptoms for many years. Importantly, Table 1 also lists symptoms that were once thought to be linked to menopause but which recent studies indicate are not. Some of these symptoms – such as mood swings, depression, and reduced libido – could b ...