Quiz 3 – Aldehydes and Ketones 1 Which of the following reactions
... 7 You have two C6H10O ketones, I and II. Both are optically active, but I is racemized by treatment with base and II is not. Wolff-Kishner reduction of both ketones gives the same achiral hydrocarbon, formula C6H12. What reasonable structures may be assigned to I and II? A) I is 3-methyl-4-penten-2- ...
... 7 You have two C6H10O ketones, I and II. Both are optically active, but I is racemized by treatment with base and II is not. Wolff-Kishner reduction of both ketones gives the same achiral hydrocarbon, formula C6H12. What reasonable structures may be assigned to I and II? A) I is 3-methyl-4-penten-2- ...
Here is the Original File - University of New Hampshire
... chemistry, biology, and medicine as it permits quantitative determination of various compounds at low concentrations1. By Wittig reaction, trans-9-(2phenylethenyl)anthracene can be synthesized, which can used in a wide variety of chemiluminescent experiments due to its blue fluorescence2. Proper pre ...
... chemistry, biology, and medicine as it permits quantitative determination of various compounds at low concentrations1. By Wittig reaction, trans-9-(2phenylethenyl)anthracene can be synthesized, which can used in a wide variety of chemiluminescent experiments due to its blue fluorescence2. Proper pre ...
Substitution reactions of carbonyl compounds at the α
... acetates, respectively. As you might expect, alkylation of an enolate is a powerful tool for the formation of carbon-carbon bonds under relatively mild conditions. The Haloform Reaction: While enolates are great for forming new carbon-carbon bonds, the first reaction we’ll look at is a method for t ...
... acetates, respectively. As you might expect, alkylation of an enolate is a powerful tool for the formation of carbon-carbon bonds under relatively mild conditions. The Haloform Reaction: While enolates are great for forming new carbon-carbon bonds, the first reaction we’ll look at is a method for t ...
Aldehydes and Ketones
... ketone with a phosphonium ylide- a compound with a negatively-charged carbon bonded to a positively-charged phosphorus atom. The result is the replacement of the carbonyl oxygen with the carbon group on the ylide. We will learn how to prepare this Wittig reagent (the ylide), and how it reacts with t ...
... ketone with a phosphonium ylide- a compound with a negatively-charged carbon bonded to a positively-charged phosphorus atom. The result is the replacement of the carbonyl oxygen with the carbon group on the ylide. We will learn how to prepare this Wittig reagent (the ylide), and how it reacts with t ...
nucleophile (亲核试剂)
... shared the 1979 Nobel Prize for Chemistry. In the Wittig reaction, he first demonstrated 1954, a carbonyl compound (aldehyde or ketone) reacts with an organic phosphorus compound, an alkylidenetriphenylphosphorane, (C6H5)3P=CR2, where R is a hydrogen atom or an organic radical. The alkylidene group ...
... shared the 1979 Nobel Prize for Chemistry. In the Wittig reaction, he first demonstrated 1954, a carbonyl compound (aldehyde or ketone) reacts with an organic phosphorus compound, an alkylidenetriphenylphosphorane, (C6H5)3P=CR2, where R is a hydrogen atom or an organic radical. The alkylidene group ...
aldehyde ketone
... Aldehydes have a hydrogen attached to the carbonyl group. Two groups react differently and can be distinguished. ...
... Aldehydes have a hydrogen attached to the carbonyl group. Two groups react differently and can be distinguished. ...
Student Instructions from Laboratory Manual
... bar. With vigorous stirring, slowly add 2.5 equiv of lithium triethylborohydride [aka, SuperHydride®] (1.0-M solution in THF) by syringe, cap the flask, and allow the reaction to proceed for 20 min. Add 3 equiv of methyl iodide slowly by calibrated micropipette and stir the resulting reaction mixtur ...
... bar. With vigorous stirring, slowly add 2.5 equiv of lithium triethylborohydride [aka, SuperHydride®] (1.0-M solution in THF) by syringe, cap the flask, and allow the reaction to proceed for 20 min. Add 3 equiv of methyl iodide slowly by calibrated micropipette and stir the resulting reaction mixtur ...
Organometallic Reagents: Sources of Nucleophilic Carbon for
... The alkyl group in alkylmetals is strongly basic. Carbocations are the conjugate bases of alkanes (estimated pKa’s of about 50), and as a result are extremely basic, much more so than amines or alkoxides. Because of their basicity, carbocations are extremely sensitive to moisture or other acidic fu ...
... The alkyl group in alkylmetals is strongly basic. Carbocations are the conjugate bases of alkanes (estimated pKa’s of about 50), and as a result are extremely basic, much more so than amines or alkoxides. Because of their basicity, carbocations are extremely sensitive to moisture or other acidic fu ...
Addition reactions
... Addition reactions In addition reactions the substrate gains atoms (or groups) from the reactant but doesn’t lose any. • Substrate is unsaturated (Has multiple bond(s)) • Occur easily & quickly because σ-bonds are more stable than the π bonds they replace nucleophilic addition ...
... Addition reactions In addition reactions the substrate gains atoms (or groups) from the reactant but doesn’t lose any. • Substrate is unsaturated (Has multiple bond(s)) • Occur easily & quickly because σ-bonds are more stable than the π bonds they replace nucleophilic addition ...
Solid phase reactions II
... (e.g. active esters, anhydrides) best conditions highly dependent on the steric and electronic nature of amine and carboxylic acid ...
... (e.g. active esters, anhydrides) best conditions highly dependent on the steric and electronic nature of amine and carboxylic acid ...
ppt
... Spectra of Aldehydes and Ketones: The 1H chemical shift range for the aldehyde proton is 9-10 ppm The aldehyde proton will couple to the protons on the -carbon with a typical coupling constant of J 2 Hz A carbonyl will slightly deshield the protons on the -carbon; typical chemical shift range ...
... Spectra of Aldehydes and Ketones: The 1H chemical shift range for the aldehyde proton is 9-10 ppm The aldehyde proton will couple to the protons on the -carbon with a typical coupling constant of J 2 Hz A carbonyl will slightly deshield the protons on the -carbon; typical chemical shift range ...
Answers
... 2. Predict the products of these elimination reactions. Two of them do not occur as written. For these, say, NO RXN, and explain why. ...
... 2. Predict the products of these elimination reactions. Two of them do not occur as written. For these, say, NO RXN, and explain why. ...
Dehydration of 3,3-dimethyl-2-butanol to make alkenes March 1 & 3
... Synthesis of Alkenes 1: Miniscale Synthesis of Alkenes Via the Acid-catalyzed Dehydration of 3,3-dimethyl-2-butanol ...
... Synthesis of Alkenes 1: Miniscale Synthesis of Alkenes Via the Acid-catalyzed Dehydration of 3,3-dimethyl-2-butanol ...
DEHYDRATION - ALKENE TEST EXERCISES
... DEHYDRATION - ALKENE TEST EXERCISES 1. Give a detailed mechanism for the acid-catalyzed dehydration of cyclohexanol to cyclohexene. ...
... DEHYDRATION - ALKENE TEST EXERCISES 1. Give a detailed mechanism for the acid-catalyzed dehydration of cyclohexanol to cyclohexene. ...
Addition Reactions
... acid-catalyzed hydration of an alkene is regioselective; hydrogen adds preferentially to the sp2 carbon with less # of hydrogens. ...
... acid-catalyzed hydration of an alkene is regioselective; hydrogen adds preferentially to the sp2 carbon with less # of hydrogens. ...
