The Non-LTR Retrotransposon Rex3 from the Fish Xiphophorus is
... Fishes make up more than half of the 48,000 species of living vertebrates. They should therefore possess genetic tools for speciation-associated genome evolution. Transposons may be one of the factors fulfilling this function due to their ability to move within genomes, to generate mutations, and to ...
... Fishes make up more than half of the 48,000 species of living vertebrates. They should therefore possess genetic tools for speciation-associated genome evolution. Transposons may be one of the factors fulfilling this function due to their ability to move within genomes, to generate mutations, and to ...
si RNA
... The use of RNA interference for artificially manipulating gene expression was initially limited by the activation of cellular antiviral mechanisms. Exposure of cells to sequences longer than 30 nucleotides induces interferon gene expression resulting in non-specific RNA degradation and reduced prote ...
... The use of RNA interference for artificially manipulating gene expression was initially limited by the activation of cellular antiviral mechanisms. Exposure of cells to sequences longer than 30 nucleotides induces interferon gene expression resulting in non-specific RNA degradation and reduced prote ...
Genetic architecture of intelligence from SNP - cog
... Implications of low MAF: epistasis, additivity and all that Why is most of the variance additive? Where is the epistasis that our wet lab colleagues see every day? If most causal variants are rare (e.g., MAF < 0.1), then when two individuals differ at a locus we likely find AA vs Aa. Very few indiv ...
... Implications of low MAF: epistasis, additivity and all that Why is most of the variance additive? Where is the epistasis that our wet lab colleagues see every day? If most causal variants are rare (e.g., MAF < 0.1), then when two individuals differ at a locus we likely find AA vs Aa. Very few indiv ...
View - BioOne
... herbicides because they possess many characteristics of higher plants. Six days after the application of monosulfuron at 0.03 to 0.3 nmol L21 under laboratory conditions, growth of the nitrogen-fixing cyanobacteria Anabaena flos-aquae, Anabaena azollae, and Anabaena azotica was stimulated, but at hi ...
... herbicides because they possess many characteristics of higher plants. Six days after the application of monosulfuron at 0.03 to 0.3 nmol L21 under laboratory conditions, growth of the nitrogen-fixing cyanobacteria Anabaena flos-aquae, Anabaena azollae, and Anabaena azotica was stimulated, but at hi ...
What is transcription
... ☆ Gene functions (majority) are expressed as the proteins they encode: Translation Translation = RNA → protein ...
... ☆ Gene functions (majority) are expressed as the proteins they encode: Translation Translation = RNA → protein ...
Genotype–phenotype correlations in laminopathies
... Marie–Tooth disorder type 2B). The LMNA gene is alternatively spliced to produce the type V intermediate filament proteins lamin A, C, C2 and del10. Together with B-type lamins, lamin A and C are the major components of the nuclear lamina (a fibrous proteinaceous meshwork underlying the nuclear enve ...
... Marie–Tooth disorder type 2B). The LMNA gene is alternatively spliced to produce the type V intermediate filament proteins lamin A, C, C2 and del10. Together with B-type lamins, lamin A and C are the major components of the nuclear lamina (a fibrous proteinaceous meshwork underlying the nuclear enve ...
Biogenesis and significance of lipofuscin in the equine thyroid gland
... lysosomes, and are defined by characteristic morphology, colour, fluorescence, and histochemistry. They increase in number with age in post-mitotic cells, and are regarded as markers of the aging process. Lipofuscin is widely assumed to consist of products of peroxidised fatty acids cross-linked wit ...
... lysosomes, and are defined by characteristic morphology, colour, fluorescence, and histochemistry. They increase in number with age in post-mitotic cells, and are regarded as markers of the aging process. Lipofuscin is widely assumed to consist of products of peroxidised fatty acids cross-linked wit ...
T-box-mediated control of the anabolic proline biosynthetic genes of
... Bacillus subtilis possesses interlinked routes for the synthesis of proline. The ProJ–ProA–ProH route is responsible for the production of proline as an osmoprotectant, and the ProB–ProA–ProI route provides proline for protein synthesis. We show here that the transcription of the anabolic proBA and ...
... Bacillus subtilis possesses interlinked routes for the synthesis of proline. The ProJ–ProA–ProH route is responsible for the production of proline as an osmoprotectant, and the ProB–ProA–ProI route provides proline for protein synthesis. We show here that the transcription of the anabolic proBA and ...
A novel arginine substitution mutation in 1A domain and a novel 27
... region have been reported.26–29 The proband of family B carries a novel duplication insertion of 27 nucleotides (1222ins27). This type of mutation is unique for a number of different reasons. Firstly, in-frame insertion or deletion mutations are extremely rare in keratin diseases (table 2), and this ...
... region have been reported.26–29 The proband of family B carries a novel duplication insertion of 27 nucleotides (1222ins27). This type of mutation is unique for a number of different reasons. Firstly, in-frame insertion or deletion mutations are extremely rare in keratin diseases (table 2), and this ...
Acid-Base Balance
... Rapid– good circulation + CO2 lipid soluble Typically pCO2 drives respiratory control via pH 1A physiology with CO2 absorber CSF has little buffering capacity ...
... Rapid– good circulation + CO2 lipid soluble Typically pCO2 drives respiratory control via pH 1A physiology with CO2 absorber CSF has little buffering capacity ...
GST II: ---Title--- - Digital Biology Laboratory
... amino acid substitution matrices (20X20) account for probability of one amino acid being substituted for another: frequency of substitution - genetic code tolerance for changes - natural selection penalize residues pairs with a low probability of mutation in evolution and rewards pairs with a hi ...
... amino acid substitution matrices (20X20) account for probability of one amino acid being substituted for another: frequency of substitution - genetic code tolerance for changes - natural selection penalize residues pairs with a low probability of mutation in evolution and rewards pairs with a hi ...
Chemistry You Need to Know
... Cross-linkages are chemical bonds (as opposed to the physical attractions of intermolecular forces) Once formed, a chemical reaction must occur to break them (remember thermoset plastics!) Cross-linkages can change a liquid polymer into a solid or gel-like polymer ...
... Cross-linkages are chemical bonds (as opposed to the physical attractions of intermolecular forces) Once formed, a chemical reaction must occur to break them (remember thermoset plastics!) Cross-linkages can change a liquid polymer into a solid or gel-like polymer ...
Applied and Environmental Microbiology
... anaerobic conditions (12). In A. amazonense, a noncovalent, less complete inhibition occurs (13, 42). Ammonium, the first product of nitrogen fixation, is assimilated through the glutamine synthetase (GS)-glutamate synthase (GOGAT) pathway (2, 30). GS is regulated by the nitrogen status of the cell ...
... anaerobic conditions (12). In A. amazonense, a noncovalent, less complete inhibition occurs (13, 42). Ammonium, the first product of nitrogen fixation, is assimilated through the glutamine synthetase (GS)-glutamate synthase (GOGAT) pathway (2, 30). GS is regulated by the nitrogen status of the cell ...
WO 2012/149481 Al
... - P), serine (ser - S), threonine (thr - T), tryptophan (trp - W), tyrosine (tyr - Y), or valine (val - V). In certain aspects, any two residue combinations of residues 1 to 7 of SEQ ID NO:2 can be alter. In a further aspect, any three residue combinations of residues 1 to 7 of SEQ ID NO:2 can be a ...
... - P), serine (ser - S), threonine (thr - T), tryptophan (trp - W), tyrosine (tyr - Y), or valine (val - V). In certain aspects, any two residue combinations of residues 1 to 7 of SEQ ID NO:2 can be alter. In a further aspect, any three residue combinations of residues 1 to 7 of SEQ ID NO:2 can be a ...
Gene silencing: RNA makes RNA makes no
... [2]. There are other similar examples in plants and, collectively, these phenomena are referred to as post-transcriptional gene silencing, although ‘RNA silencing’ may be a more accurate term. Now, through the genetic analysis of quelling in Neurospora, new light has been shed on the mechanism of po ...
... [2]. There are other similar examples in plants and, collectively, these phenomena are referred to as post-transcriptional gene silencing, although ‘RNA silencing’ may be a more accurate term. Now, through the genetic analysis of quelling in Neurospora, new light has been shed on the mechanism of po ...
OptCDR: a general computational method for the design
... 2000) method and then expanded to include amino acids with similar chemical properties. When these sequence-based rules were not sufficient (25% of cases), the framework of the antibody variable region was aligned to a consensus framework and structural analysis was used to identify the CDRs. Throu ...
... 2000) method and then expanded to include amino acids with similar chemical properties. When these sequence-based rules were not sufficient (25% of cases), the framework of the antibody variable region was aligned to a consensus framework and structural analysis was used to identify the CDRs. Throu ...
Transcriptional Attenuation
... Transcriptional attenuation might, in the broadest sense, include any phenomenon that reduces the extent or rate of transcription. In studies of bacterial gene regulation, however, it has acquired a more restricted definition and is used to describe a mechanism in which the level of transcriptional ...
... Transcriptional attenuation might, in the broadest sense, include any phenomenon that reduces the extent or rate of transcription. In studies of bacterial gene regulation, however, it has acquired a more restricted definition and is used to describe a mechanism in which the level of transcriptional ...
Supplementary document Trehalose/2
... method (Falicia Goh et al 2011). Cell pellets were washed three times in a sterile isotonic ...
... method (Falicia Goh et al 2011). Cell pellets were washed three times in a sterile isotonic ...
From bedside to bench: how to analyze a splicing
... harboring a potentially lethal LQT mutation. In these cases, correct diagnosis is of paramount importance, as identification of one such mutation would allow the appropriate life saving medication to be administered to the patient as well as screening of all at risk family members. Indeed, a scenari ...
... harboring a potentially lethal LQT mutation. In these cases, correct diagnosis is of paramount importance, as identification of one such mutation would allow the appropriate life saving medication to be administered to the patient as well as screening of all at risk family members. Indeed, a scenari ...
Electrophoretic Extraction and Proteomic Characterization of
... amide bonds as found in proteins [2–4]. Protein building blocks, such as total hydrolysable amino acids (THAAs, total amino acids that can be extracted using 6 N HCl), are found to account for up to 30%–40% of particulate nitrogen in marine sediments [5–8]. In addition to proteins representing the l ...
... amide bonds as found in proteins [2–4]. Protein building blocks, such as total hydrolysable amino acids (THAAs, total amino acids that can be extracted using 6 N HCl), are found to account for up to 30%–40% of particulate nitrogen in marine sediments [5–8]. In addition to proteins representing the l ...
(THCA) synthase gene in
... sponding to the THCA synthase gene were separated into two groups, ‘‘drug-type’’ and ‘‘fiber-type’’. The 62 nucleotides from the six ‘‘drug-type’’ strains (#013, #020, #054, #001, #053 and #010) were substituted with different nucleotides from the seven ‘‘fiber-type’’ strains (#009, #045, #078, #011 ...
... sponding to the THCA synthase gene were separated into two groups, ‘‘drug-type’’ and ‘‘fiber-type’’. The 62 nucleotides from the six ‘‘drug-type’’ strains (#013, #020, #054, #001, #053 and #010) were substituted with different nucleotides from the seven ‘‘fiber-type’’ strains (#009, #045, #078, #011 ...
A1071 GM Canola MON88302 AppR SD1
... Canola line MON88302 expresses one novel protein, CP4 EPSPS. The level of CP4 EPSPS is lowest in the pollen (approximately 9 µg/g dry weight) and highest in leaves at the stage where stem elongation (bolting) begins (approximately 230 µg/g dry weight). The level in the mature seed is approximately 2 ...
... Canola line MON88302 expresses one novel protein, CP4 EPSPS. The level of CP4 EPSPS is lowest in the pollen (approximately 9 µg/g dry weight) and highest in leaves at the stage where stem elongation (bolting) begins (approximately 230 µg/g dry weight). The level in the mature seed is approximately 2 ...
de novo
... novo GSH biosynthesis. • The -glutamyl-amino acid couple also re-enters the cell by an amino acid transporter. Once in the cell the amino acid and the -glutamyl moiety are separated. The carrier amino acid is often cystine, and this process has been hypothesized to be important in the re-cycling o ...
... novo GSH biosynthesis. • The -glutamyl-amino acid couple also re-enters the cell by an amino acid transporter. Once in the cell the amino acid and the -glutamyl moiety are separated. The carrier amino acid is often cystine, and this process has been hypothesized to be important in the re-cycling o ...
J Molecular Biology 307:939-949, 2001
... Multiple alignment-to-sequence searches can identify genuine relations that are not found by sequence-to-sequence searches.1 ± 6 This is the result of identifying what residues are preferred in the conserved sequence regions of the family members and of not using sequence regions that are not conser ...
... Multiple alignment-to-sequence searches can identify genuine relations that are not found by sequence-to-sequence searches.1 ± 6 This is the result of identifying what residues are preferred in the conserved sequence regions of the family members and of not using sequence regions that are not conser ...
Micro 2 transcripts to be made into flashcards
... NOTE: Know which wells have what color of a positive test: Brown, Orange or Red, Blue, Yellow, Diffused black pigment, Pink ring on top, etc. CATALASE TEST (Control: positive = Staph aureus) Some facultative aerobes have the enzyme called catalase, which breaks down hydrogen peroxide (H2O2) into har ...
... NOTE: Know which wells have what color of a positive test: Brown, Orange or Red, Blue, Yellow, Diffused black pigment, Pink ring on top, etc. CATALASE TEST (Control: positive = Staph aureus) Some facultative aerobes have the enzyme called catalase, which breaks down hydrogen peroxide (H2O2) into har ...
Genetic code
The genetic code is the set of rules by which information encoded within genetic material (DNA or mRNA sequences) is translated into proteins by living cells. Biological decoding is accomplished by the ribosome, which links amino acids in an order specified by mRNA, using transfer RNA (tRNA) molecules to carry amino acids and to read the mRNA three nucleotides at a time. The genetic code is highly similar among all organisms and can be expressed in a simple table with 64 entries.The code defines how sequences of these nucleotide triplets, called codons, specify which amino acid will be added next during protein synthesis. With some exceptions, a three-nucleotide codon in a nucleic acid sequence specifies a single amino acid. Because the vast majority of genes are encoded with exactly the same code (see the RNA codon table), this particular code is often referred to as the canonical or standard genetic code, or simply the genetic code, though in fact some variant codes have evolved. For example, protein synthesis in human mitochondria relies on a genetic code that differs from the standard genetic code.While the genetic code determines the protein sequence for a given coding region, other genomic regions can influence when and where these proteins are produced.