
Enzyme Mechanisms - Illinois Institute of Technology
... Compare L for real DNA to what it would be if it were relaxed (W=0): That’s L = L - L0 Sometimes we want = superhelix density = specific linking difference = L / L0 Natural circular DNA always has < 0 ...
... Compare L for real DNA to what it would be if it were relaxed (W=0): That’s L = L - L0 Sometimes we want = superhelix density = specific linking difference = L / L0 Natural circular DNA always has < 0 ...
Wheeler Quantitative Genetics
... Breeding Value: The sum of all average allelic effect at each locus influencing the trait(s) of interest. (Alleles, not genotypes are passed on to the next generation) Breeding value is a concept associated with parents in a sexually breeding population. It can be measured. Historically, average all ...
... Breeding Value: The sum of all average allelic effect at each locus influencing the trait(s) of interest. (Alleles, not genotypes are passed on to the next generation) Breeding value is a concept associated with parents in a sexually breeding population. It can be measured. Historically, average all ...
catalogue 2012 - olimp
... the leading world experts in the area of sport nutrition with whom we cooperate on a regular basis and the products themselves, put us at the top of the most innovative companies implementing the state of the art and most effective solutions in sport nutrition. Over 20 years of market presence and t ...
... the leading world experts in the area of sport nutrition with whom we cooperate on a regular basis and the products themselves, put us at the top of the most innovative companies implementing the state of the art and most effective solutions in sport nutrition. Over 20 years of market presence and t ...
Darnell, JC, Warren, ST and Darnell, RB: The fragile X mental retardation protein, FMRP, recognizes G-quartets. Mental Retardation and Developmental Disabilities Research Reviews 10:49-52 (2004).
... found to localize to the polysome fraction of the cytoplasm [Corbin et al., 1997; Feng et al., 1997a; Feng et al., 1997b], and this localization was associated with functional polysomes, as it was lost in the presence of sodium azide or sodium fluoride, agents that cause ribosomes to run off translat ...
... found to localize to the polysome fraction of the cytoplasm [Corbin et al., 1997; Feng et al., 1997a; Feng et al., 1997b], and this localization was associated with functional polysomes, as it was lost in the presence of sodium azide or sodium fluoride, agents that cause ribosomes to run off translat ...
Improved production of poly-γ-glutamate by newly Bacillus subtilis
... The D-glutamate content was over 50% in every γ-PGA produced under the conditions used, suggesting that the bacterium possesses a synthetic pathway to produce D-glutamate, the main precursor of γ-PGA, from L-glutamate.To obtain a clue as to the nature of the D-glutamate synthetic pathway in B. subti ...
... The D-glutamate content was over 50% in every γ-PGA produced under the conditions used, suggesting that the bacterium possesses a synthetic pathway to produce D-glutamate, the main precursor of γ-PGA, from L-glutamate.To obtain a clue as to the nature of the D-glutamate synthetic pathway in B. subti ...
Unique amino acid signatures that are evolutionarily conserved
... homodimers is unclear. The abundance of keratin polypeptides, coupled with their cellspecific expression suggests that keratins have evolved to fulfill specific requirements for specialized epithelial tissues. To support this hypothesis, several studies have demonstrated that the loss of a particula ...
... homodimers is unclear. The abundance of keratin polypeptides, coupled with their cellspecific expression suggests that keratins have evolved to fulfill specific requirements for specialized epithelial tissues. To support this hypothesis, several studies have demonstrated that the loss of a particula ...
Evolution of colour vision in primates
... The MWS and LWS opsin genes are very similar. In fact, their DNA sequences are almost 98 % identical, even including the non-coding sequences of their introns. There are only 24 nucleotides that differentiate the two coding sequences, which corresponds to 15 amino acid changes between the proteins e ...
... The MWS and LWS opsin genes are very similar. In fact, their DNA sequences are almost 98 % identical, even including the non-coding sequences of their introns. There are only 24 nucleotides that differentiate the two coding sequences, which corresponds to 15 amino acid changes between the proteins e ...
spectroscopic studies of mosquito iridescent virus, its capsid
... Optical spectroscopy is one of the efficient and informative methods of studying viruses. It provides well reproducible results and is a powerful supplement to conventional biological methods of studying the living organisms. Thus, it allows one to determine the chemical composition of the capsid pr ...
... Optical spectroscopy is one of the efficient and informative methods of studying viruses. It provides well reproducible results and is a powerful supplement to conventional biological methods of studying the living organisms. Thus, it allows one to determine the chemical composition of the capsid pr ...
Profile TildeCRF: a new tool for protein homology detection
... [DARWIN, 1868], Gregory Mendel provided in parallel a logical explanation for the mechanism of heredity after his experiments on pea plant hybridization, which led him to formulate his laws of inheritance [MENDEL, 1866]. Nonetheless, it was not until 1953 that James D. Watson and Francis Crick first ...
... [DARWIN, 1868], Gregory Mendel provided in parallel a logical explanation for the mechanism of heredity after his experiments on pea plant hybridization, which led him to formulate his laws of inheritance [MENDEL, 1866]. Nonetheless, it was not until 1953 that James D. Watson and Francis Crick first ...
Amino Acid Metabolism
... • The nitrogenase reaction. ATP hydrolysis coupled to electron transfer from N. reductase to P-cluster. • This is followed by conformational change in N. reductase so it does not bind to Nitrogenase. •ADP-N. reductase dissociates allowing another ATP-N. reductase to bind. ...
... • The nitrogenase reaction. ATP hydrolysis coupled to electron transfer from N. reductase to P-cluster. • This is followed by conformational change in N. reductase so it does not bind to Nitrogenase. •ADP-N. reductase dissociates allowing another ATP-N. reductase to bind. ...
Appendix A: General Remarks on Handling RNA
... buffers. DEPC is highly unstable in the presence of Tris buffers and decomposes rapidly into ethanol and CO2. When preparing Tris buffers, treat water with DEPC first, and then dissolve Tris to make the appropriate buffer. Trace amounts of DEPC will modify purine residues in RNA by carboxymethylatio ...
... buffers. DEPC is highly unstable in the presence of Tris buffers and decomposes rapidly into ethanol and CO2. When preparing Tris buffers, treat water with DEPC first, and then dissolve Tris to make the appropriate buffer. Trace amounts of DEPC will modify purine residues in RNA by carboxymethylatio ...
Iron mediated methylthiolation of tRNA as a regulator of operon
... efficiency of the normal tRNA (not shown). The slightly better performance in reading poly-UC may mean that the ability of altered tRNA p e to read codon UUU is reduced more than its ability to read UUC. Preliminary results showed that altered tRNA r p also had a reduced translational capacity when ...
... efficiency of the normal tRNA (not shown). The slightly better performance in reading poly-UC may mean that the ability of altered tRNA p e to read codon UUU is reduced more than its ability to read UUC. Preliminary results showed that altered tRNA r p also had a reduced translational capacity when ...
The colorimetric estimation of inorganic phosphate
... molybdate in an acid solution to form phosphomolybdic acid. A reducing agent such as metol is added which reduces the molybdenum to give a blue colour but does not affect the uncombined. ...
... molybdate in an acid solution to form phosphomolybdic acid. A reducing agent such as metol is added which reduces the molybdenum to give a blue colour but does not affect the uncombined. ...
Lec3
... Evolution would be very slow if populations were genetically uniform, and if only occasional mutations arose and replaced pre-existing genotypes. In order to know what the potential is for rapid evolutionary change, it would be useful to know how much genetic variation natural population contain Lew ...
... Evolution would be very slow if populations were genetically uniform, and if only occasional mutations arose and replaced pre-existing genotypes. In order to know what the potential is for rapid evolutionary change, it would be useful to know how much genetic variation natural population contain Lew ...
Conservation and relative importance of residues across protein
... fully buried in the interface, whereas the latter only contains atoms that retain partial accessibility (24, 25). The core possesses more hydrophobic residues and has a composition that is distinct from the rim or the rest of the protein surface. With the division into core and rim residues one can ...
... fully buried in the interface, whereas the latter only contains atoms that retain partial accessibility (24, 25). The core possesses more hydrophobic residues and has a composition that is distinct from the rim or the rest of the protein surface. With the division into core and rim residues one can ...
Cell-Free Protein Expression Systems
... Rabbit Reticulocyte Lysate (RRL), Nuclease-Treated, is optimized for mRNA translation by the addition of several supplements. These include hemin, which prevents activation of the heme-regulated eIF-2a kinase; an energy-generating system consisting of phosphocreatine kinase and phosphocreatine; and ...
... Rabbit Reticulocyte Lysate (RRL), Nuclease-Treated, is optimized for mRNA translation by the addition of several supplements. These include hemin, which prevents activation of the heme-regulated eIF-2a kinase; an energy-generating system consisting of phosphocreatine kinase and phosphocreatine; and ...
2 Ionic equilibria - University of Basrah
... • The strength of an acid or a base varies with the solvent. • HCl is a strong acid but it is a weak acid in glacial acetic acid. • Acetic acid, which is a weak acid, is a strong acid in liquid ammonia. • Consequently, the strength of an acid depends not ...
... • The strength of an acid or a base varies with the solvent. • HCl is a strong acid but it is a weak acid in glacial acetic acid. • Acetic acid, which is a weak acid, is a strong acid in liquid ammonia. • Consequently, the strength of an acid depends not ...
Lipid Metabolism - Creighton Chemistry Webserver
... Not enough insulin, tissues cannot take up glc efficiently from blood to use as fuel or store as fat Malonyl CoA (fatty acid biosynthesis) not formed, so carnitine acyltransferase I not inhibited Fatty acids enter mitochondria to be degraded to acetyl CoA (which cannot go to TCA because cycle interm ...
... Not enough insulin, tissues cannot take up glc efficiently from blood to use as fuel or store as fat Malonyl CoA (fatty acid biosynthesis) not formed, so carnitine acyltransferase I not inhibited Fatty acids enter mitochondria to be degraded to acetyl CoA (which cannot go to TCA because cycle interm ...
Brief Introduction of Bioinformatics
... three or four sequences in its most basic form. This method requires constructing the n-dimensional equivalent of the sequence matrix formed from two sequences, where n is the number of sequences in the query. Standard dynamic programming is first used on all pairs of query sequences and then the "a ...
... three or four sequences in its most basic form. This method requires constructing the n-dimensional equivalent of the sequence matrix formed from two sequences, where n is the number of sequences in the query. Standard dynamic programming is first used on all pairs of query sequences and then the "a ...
Agonism with the omega-3 fatty acids α-linolenic acid
... noblot, validating the immunoprecipitation procedure which would be used to detect receptor phosphorylation (Fig. 2B). ...
... noblot, validating the immunoprecipitation procedure which would be used to detect receptor phosphorylation (Fig. 2B). ...
Optimizing Restriction Site Placement for Synthetic
... The redundancy of the genetic code (64 three-base codons coding for 20 distinct amino acids) gives us the freedom to insert new restriction sites at certain places and remove them from others without changing the protein coded for by a given gene. Identifying the locations of both current and potent ...
... The redundancy of the genetic code (64 three-base codons coding for 20 distinct amino acids) gives us the freedom to insert new restriction sites at certain places and remove them from others without changing the protein coded for by a given gene. Identifying the locations of both current and potent ...
Microevolution: Comparing Like Proteins from Different Species to
... Asp Thr Leu Met Glu Lys Ala Thr Asn Glu ...
... Asp Thr Leu Met Glu Lys Ala Thr Asn Glu ...
Inheriting Genetic Conditions Handbook
... by mutations in a single gene, such as cystic fibrosis and sickle cell anemia. While a family medical history provides information about the risk of specific health concerns, having relatives with a medical condition does not mean that an individual will definitely develop that condition. On the oth ...
... by mutations in a single gene, such as cystic fibrosis and sickle cell anemia. While a family medical history provides information about the risk of specific health concerns, having relatives with a medical condition does not mean that an individual will definitely develop that condition. On the oth ...
Lec 16: Nitrogen (ammonia) assimilation
... 1. It forms AMP from ATP… (instead of forming ADP as in glutamine synthetase) 2. “Ammonia” can be free ammonia OR the amide of glutamine It turns out… using glutamine is preferred over using ammonia in this case. Therefore, this enzyme is not a major enzyme for ammonia assimilation. ...
... 1. It forms AMP from ATP… (instead of forming ADP as in glutamine synthetase) 2. “Ammonia” can be free ammonia OR the amide of glutamine It turns out… using glutamine is preferred over using ammonia in this case. Therefore, this enzyme is not a major enzyme for ammonia assimilation. ...
Genetic code

The genetic code is the set of rules by which information encoded within genetic material (DNA or mRNA sequences) is translated into proteins by living cells. Biological decoding is accomplished by the ribosome, which links amino acids in an order specified by mRNA, using transfer RNA (tRNA) molecules to carry amino acids and to read the mRNA three nucleotides at a time. The genetic code is highly similar among all organisms and can be expressed in a simple table with 64 entries.The code defines how sequences of these nucleotide triplets, called codons, specify which amino acid will be added next during protein synthesis. With some exceptions, a three-nucleotide codon in a nucleic acid sequence specifies a single amino acid. Because the vast majority of genes are encoded with exactly the same code (see the RNA codon table), this particular code is often referred to as the canonical or standard genetic code, or simply the genetic code, though in fact some variant codes have evolved. For example, protein synthesis in human mitochondria relies on a genetic code that differs from the standard genetic code.While the genetic code determines the protein sequence for a given coding region, other genomic regions can influence when and where these proteins are produced.