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How metabolites modulate metabolic flux
How metabolites modulate metabolic flux

... can affect several metabolic pathways simultaneously and, thus, cannot specifically increase a flux to produce a certain metabolite. For instance, high glucose levels will induce a high glycolytic flux. Since serine is derived from the glycolytic intermediate glycerate 3-phosphate, increased glycoly ...
Lecture_6_TCA_Cycle
Lecture_6_TCA_Cycle

... form of NADH and FADH2. The two carbon acetyl unit from acetyl CoA condenses with oxaloacetate to form citrate, which is subsequently oxidized. The high-energy electrons are used to reduce O2 to H2O. This reduction generates a proton gradient that is used to synthesize ATP. ...
Chapter 3 The Molecules of Cells
Chapter 3 The Molecules of Cells

...  The amino acid sequence of a polypeptide is programmed by a discrete unit of inheritance known as a gene.  Genes consist of DNA(deoxyribonucleic acid), a type of nucleic acid.  DNA is inherited from an organism’s parents.  DNA provides directions for its own replication.  DNA programs a cell’s ...
Proteins
Proteins

... • Body degrades ~300g pro-/day: we take in ~65-90g  Most AA’s recycled to build new proteins  Some are eliminated in feces or urine ...
Lactic Acid fermentation
Lactic Acid fermentation

... • NADH/FADH release electrons • form NAD+ and FAD ...
Repetition Summary of last lecture Energy Cell Respiration
Repetition Summary of last lecture Energy Cell Respiration

... pyruvate is reduced directly to NADH to form lactate as a waste product ...
What roles do proteins (polypeptides) play? 1. Enzymes (catalysts) 2
What roles do proteins (polypeptides) play? 1. Enzymes (catalysts) 2

... • Note the stereochemistry (geometry) • 19 of the 20 are chiral Steroisomers • 4 different groups bonded to Cα • These molecules cannot be superimposed (are mirror images of each other) • Therefore they are not identical, and are referred to as stereoisomers. • Using spectrographic instrumentation, ...
6.1 Digestion and absorption
6.1 Digestion and absorption

... forces the products of digesiton into contact with the wall of the intestine Therefore in the intestines the food is moved very slowly to allow time for digestion. http://www.austincc.edu/rfofi/NursingRvw/NursingPics/DigestivePics/Picture4.jpg ...
2.4 Proteins
2.4 Proteins

... • A polypeptide is a polymer of amino acids • Polypeptides range in length from a few monomers to more than a thousand • Each polypeptide has a unique linear sequence of amino ...
Monomers are the
Monomers are the

... sugar molecule includes a bunch of carbon atoms. Usually, a carbon atom in a sugar molecule has an H atom stuck to it and an OH stuck to it also. H + OH = H2O, so that’s why sugars are called . . . “carbohydrates.” ...
The Building Blocks Teacher Key
The Building Blocks Teacher Key

... Rice and beans combine to make a complementary protein. If toast and peanuts were combined, they would also make a complementary protein. Rice and beans are complementary proteins because they are each missing different amino acids. When combined, the missing amino acids are found in the other to ma ...
document
document

... acids (yellow), because they can give rise to ketone bodies or fatty acids. Amino acids that are degraded to pyruvate, a-ketoglutarate, succinyl CoA, fumarate, or oxaloacetate are termed glucogenic amino acids. The net synthesis of glucose from these amino acids is feasible, because these citric aci ...
Chapter 5:Bioenergetics and oxidative phosphorylation Q1: why is
Chapter 5:Bioenergetics and oxidative phosphorylation Q1: why is

... Q2: is ATP the only energy-rich compound in the body? Q3: Are NADH & FADH2 Produced in the mitochondria only? Q4: why does FADH2 produce 2ATP while NADH produce 3ATP? Q5: what are the site-specific inhibitors of the electron transport chain? Q6: Explain why NADH is oxidized by FMN? Q7: How is electr ...
Ketone Body Metabolism
Ketone Body Metabolism

Bioenergetics of Exercise and Training
Bioenergetics of Exercise and Training

... • The oxidative (hydrogen removal) metabolism of blood glucose and muscle glycogen begins with glycolysis. If oxygen is present in sufficient quantities the end product of glycolysis, pyruvate, is not converted to lactic acid but is transported to the mitochondria, where it is taken up and enters th ...
N-fluoroacetylglucosamine. This substance is known
N-fluoroacetylglucosamine. This substance is known

... In this polymerization process each acceptor molecule in the sequence is the product formed by the previous transferase (Spiro, 1970; Roseman, 1968; Roden, 1970). For illustration, some well-investigated and instructive examples of the enzymic processes involved in the biosynthesis of glycoproteins ...
cissn study guide - Science Driven Nutrition
cissn study guide - Science Driven Nutrition

... a. Creatine monohydrate is the most effective ergogenic nutritional supplement currently available to athletes in terms of increasing highintensity exercise capacity and lean body mass during training. b. Creatine monohydrate supplementation is not only safe, but possibly beneficial in regard to pre ...
How do they (or we) use the glucose?
How do they (or we) use the glucose?

... to Acetyl-coA and moves it into the mitochondria –Releases some CO2, fills up some electron carriers (2 NADH) –Has many names: prep step, grooming step, etc. ...
mitochondria structure
mitochondria structure

... They carried the electron to one electron transport Pump and donate them to the pump. So NAD and FAD are “ Oxidized” because they loss the hydrogen ion to the pump. The pump then transport the hidrogens ion to space between two membranes, where they accumalate in high enough concentration fuel to th ...
Chapter 5 : MAJOR METABOLIC PATHWAYS
Chapter 5 : MAJOR METABOLIC PATHWAYS

Document
Document

... Overall reaction: acetyl-CoA + 3NAD + E-FAD + GDP + P + 2H2O --> CoASH + 3NADH + E-FADH2 + GTP + 2CO2 ...
4 Krebs ETC
4 Krebs ETC

... • Lactic acid production in animal muscle occurs during oxygen debt • Lactic acid needs to be produced so that NAD+ can be regenerated to keep glycolysis going Net ATP produced = 2 ATP ...
Ch. 5 Lecture CH_05_Lecture_v4
Ch. 5 Lecture CH_05_Lecture_v4

... • Amino acids are linked by peptide bonds • A polypeptide is a polymer of amino acids • Polypeptides range in length from a few to more than a thousand monomers • Each polypeptide has a unique linear sequence of amino acids, with a carboxyl end (C-terminus) and an amino end (N-terminus) ...
Lipid Oxidation - anslab.iastate.edu
Lipid Oxidation - anslab.iastate.edu

... • Inflamation ...
Supplementary Notes
Supplementary Notes

... Figure 6a, lanes 5–23). One exception was Gly, which was not incorporated into GFP at all (lanes 4 and 24). Because it was confirmed that Gly was attached to the 3'-end of tRNA like the other amino acids, the complete lack of incorporation was unanticipated. We thus suspected that unknown mechanisms ...
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Fatty acid metabolism

Fatty acids are a family of molecules classified within the lipid macronutrient class. One role of fatty acids within animal metabolism is energy production in the form of adenosine triphosphate (ATP) synthesis. When compared to other macronutrient classes (carbohydrates and protein), fatty acids yield the most ATP on an energy per gram basis by a pathway called β-oxidation. In addition, fatty acids are important for energy storage, phospholipid membrane formation, and signaling pathways. Fatty acid metabolism consists of catabolic processes that generate energy and primary metabolites from fatty acids, and anabolic processes that create biologically important molecules from fatty acids and other dietary sources.
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