CD147 (Basigin/Emmprin) identifies FoxP3 CD45RO CTLA4
... has not yet led to clarification of whether a central molecular mechanism of suppression exists or whether the immune modulating activity of Tregs is composed of a repertoire of several mechanisms.12-14 This may partly be because of the fact that FoxP3 acts in concert with a set of other transcripti ...
... has not yet led to clarification of whether a central molecular mechanism of suppression exists or whether the immune modulating activity of Tregs is composed of a repertoire of several mechanisms.12-14 This may partly be because of the fact that FoxP3 acts in concert with a set of other transcripti ...
poster - Natural Killer Cell Symposium
... Natural killer (NK) cells are lymphocytes of the innate immune system that deliver a selective cytotoxic effect against target cells such as virally infected and tumor cells. NK cell function involves cytokine secretion and tissue remodeling. NK cellular cytotoxicity is delicately balanced by signal ...
... Natural killer (NK) cells are lymphocytes of the innate immune system that deliver a selective cytotoxic effect against target cells such as virally infected and tumor cells. NK cell function involves cytokine secretion and tissue remodeling. NK cellular cytotoxicity is delicately balanced by signal ...
Chapter 15 The Lymphatic System and Immunity
... lymphocytes leave the thymus and bone marrow. They “seed” the lymph nodes, spleen, and other lymphoid tissues where they encounter their antigen. 3 Antigen-activated immunocompetent ...
... lymphocytes leave the thymus and bone marrow. They “seed” the lymph nodes, spleen, and other lymphoid tissues where they encounter their antigen. 3 Antigen-activated immunocompetent ...
Early life cytokines, viral infections and IgE
... polarisation of Th cells is more complex [18], and that Th1- and Th2-type of cytokines can even be co-expressed in the same cell [19]. It is becoming clear that Th1 and Th2 cells are not exclusive in their production of Th1- and Th2-type of cytokines, which has led to the conclusion that not only Th ...
... polarisation of Th cells is more complex [18], and that Th1- and Th2-type of cytokines can even be co-expressed in the same cell [19]. It is becoming clear that Th1 and Th2 cells are not exclusive in their production of Th1- and Th2-type of cytokines, which has led to the conclusion that not only Th ...
Functional Characterization of the CD300e Leukocyte Receptor Tamara Brckalo
... progenitor shared with neutrophils, and are then released into peripheral blood where they circulate for several days before entering tissues. They constitute a systemic reservoir of myeloid precursors that give rise to a variety of tissue resident macrophages, and also to specialized cells such as ...
... progenitor shared with neutrophils, and are then released into peripheral blood where they circulate for several days before entering tissues. They constitute a systemic reservoir of myeloid precursors that give rise to a variety of tissue resident macrophages, and also to specialized cells such as ...
antigen saturation, natural antibodies and a quantitative
... regeneration and healing (16). In addition to B1 cells, MZ B cells also contribute to the fast production of upon challenge (17). These two populations are the cells responsible for thymus independent (TI) responses. Is there, then, a difference between natural antibodies and TI antibody response ...
... regeneration and healing (16). In addition to B1 cells, MZ B cells also contribute to the fast production of upon challenge (17). These two populations are the cells responsible for thymus independent (TI) responses. Is there, then, a difference between natural antibodies and TI antibody response ...
CD4 § T-Cells from Mice Immunized to
... Tumor-immune CD4 § T-Ceils but Not CD8 § T-Cells Show Specific Proliferation to Tumor-pulsed D C . W h e n C D 4 + and C D 8 § T-cell subgroups were each prepared from both naive and tumori m m u n e mice, only t u m o r - i m m u n e C D 4 + T-cells d e m o n s t r a t e d specific proliferation w ...
... Tumor-immune CD4 § T-Ceils but Not CD8 § T-Cells Show Specific Proliferation to Tumor-pulsed D C . W h e n C D 4 + and C D 8 § T-cell subgroups were each prepared from both naive and tumori m m u n e mice, only t u m o r - i m m u n e C D 4 + T-cells d e m o n s t r a t e d specific proliferation w ...
Passive or Active Immunization with Myelin Basic Protein Promotes
... control rats injected with PBS in IFA. Morphometric analysis, immunohistochemical staining, and diffusion anisotropy magnetic resonance imaging showed that the behavioral outcome was correlated with tissue preservation. The results suggest that T cell-mediated immune activity, achieved by either ado ...
... control rats injected with PBS in IFA. Morphometric analysis, immunohistochemical staining, and diffusion anisotropy magnetic resonance imaging showed that the behavioral outcome was correlated with tissue preservation. The results suggest that T cell-mediated immune activity, achieved by either ado ...
Induced CD4+Foxp3+ Regulatory T Cells in Immune Tolerance
... a decisive factor in Helios expression on iTreg cells, rather than in nTreg or iTreg cell origin (30). In this case, the authors used T cells from TCR–transgenic RAG-deficient mice (which lack nTreg cells) and differentiated them to iTreg cells in vitro using TGF-β and IL-2 and two different activati ...
... a decisive factor in Helios expression on iTreg cells, rather than in nTreg or iTreg cell origin (30). In this case, the authors used T cells from TCR–transgenic RAG-deficient mice (which lack nTreg cells) and differentiated them to iTreg cells in vitro using TGF-β and IL-2 and two different activati ...
An intestinal commensal symbiosis factor controls
... survival strategies employed. Symbionts live in a lifelong mutualistic pattern with the host whereas pathobionts are often opportunistic pathogens5. To facilitate co-existence, symbionts must limit aggressive immune attacks or induce immune tolerance by utilizing some microbial products as symbiosis ...
... survival strategies employed. Symbionts live in a lifelong mutualistic pattern with the host whereas pathobionts are often opportunistic pathogens5. To facilitate co-existence, symbionts must limit aggressive immune attacks or induce immune tolerance by utilizing some microbial products as symbiosis ...
Antigen Presentation to T Lymphocytes
... Various tolerance mechanisms normally prevent self peptides from initiating an immune response; when these mechanisms fail, self peptides can become the target of autoimmune responses, as discussed in Chapter 15. Other classes of T cells, such as MAIT cells and γ:δ T cells (see Sections 4-18 and 4-2 ...
... Various tolerance mechanisms normally prevent self peptides from initiating an immune response; when these mechanisms fail, self peptides can become the target of autoimmune responses, as discussed in Chapter 15. Other classes of T cells, such as MAIT cells and γ:δ T cells (see Sections 4-18 and 4-2 ...
Robertson et al. 2003 Seminal priming
... effect of this immune response on pregnancy outcome was identified in experiments showing that uterine ‘priming’ with semen can promote implantation and fetal growth in subsequent pregnancies, in a partnerspecific manner (Beer et al., 1975). Consistent with an immunological mechanism, removal of lym ...
... effect of this immune response on pregnancy outcome was identified in experiments showing that uterine ‘priming’ with semen can promote implantation and fetal growth in subsequent pregnancies, in a partnerspecific manner (Beer et al., 1975). Consistent with an immunological mechanism, removal of lym ...
Nerve activates contraction
... • Increased local blood supply leads to the characteristic swelling, redness, and heat of inflammation. ...
... • Increased local blood supply leads to the characteristic swelling, redness, and heat of inflammation. ...
CHAPTER 7 Immune defences against pathogens
... and tissues. White blood cells are greatly outnumbered in the blood by the oxygen-carrying red blood cells. White blood cells are present in normal blood at concentrations in the range of 4000 to 10 000 cells per microlitre. Contrast this with red blood cells, which are present at concentrations ran ...
... and tissues. White blood cells are greatly outnumbered in the blood by the oxygen-carrying red blood cells. White blood cells are present in normal blood at concentrations in the range of 4000 to 10 000 cells per microlitre. Contrast this with red blood cells, which are present at concentrations ran ...
Publications de l`équipe - Centre de recherche de l`Institut Curie
... Mature dendritic cells secrete exosomes with strong ability to induce antigenspecific effector immune responses. Blood cells, molecules & diseases : 89-93 ...
... Mature dendritic cells secrete exosomes with strong ability to induce antigenspecific effector immune responses. Blood cells, molecules & diseases : 89-93 ...
HEVs, lymphatics and homeostatic immune cell trafficking in lymph
... Figure 2 | Entry of lymphocytes through HEVs — the multistep adhesion cascade. a | The image shows the inguinal lymph node venular tree, visualized by intravital microscopy. The high endothelial venule (HEV) network is revealed following intravenous injection of the fluorescently labelled HEV-speci ...
... Figure 2 | Entry of lymphocytes through HEVs — the multistep adhesion cascade. a | The image shows the inguinal lymph node venular tree, visualized by intravital microscopy. The high endothelial venule (HEV) network is revealed following intravenous injection of the fluorescently labelled HEV-speci ...
Investigation of the humoral and cellular immune responses of
... Significant progress has been made toward understanding how pathogenic bacteria promote their survival within the host through the regulated expression of bacterial virulence genes (ROSENBERG et al., 2000). The organisms that successfully survive in the macrophages vary in their approach with which ...
... Significant progress has been made toward understanding how pathogenic bacteria promote their survival within the host through the regulated expression of bacterial virulence genes (ROSENBERG et al., 2000). The organisms that successfully survive in the macrophages vary in their approach with which ...
The Thymus Gland
... fist), and continues to grow throughout childhood up to the age of puberty when it weighs about 1.2 oz (35 grams). Then it gradually decreases in size until it blends in with the surrounding tissue. Beginning during fetal development, the thymus processes many of the body's lymphocytes, which migrat ...
... fist), and continues to grow throughout childhood up to the age of puberty when it weighs about 1.2 oz (35 grams). Then it gradually decreases in size until it blends in with the surrounding tissue. Beginning during fetal development, the thymus processes many of the body's lymphocytes, which migrat ...
PDF
... corticosteroid-induced cleft palate (Melnick et al. 1981a), corticosteroid treatment does not appear to alter the detectable spatiotemporal distribution of H-2 antigens in developing palates of embryonic BIO.A mice. These data suggest that we should look elsewhere for the mechanism of steroid-induce ...
... corticosteroid-induced cleft palate (Melnick et al. 1981a), corticosteroid treatment does not appear to alter the detectable spatiotemporal distribution of H-2 antigens in developing palates of embryonic BIO.A mice. These data suggest that we should look elsewhere for the mechanism of steroid-induce ...
Full Text - The International Journal of Developmental Biology
... al., 2001). Whether zebrafish eosinophils are the functional orthologues of these cells remains to be determined. Surveys with toluidine blue, a stain for the metachromatic granules of mammalian mast cells, failed to identify any positively staining leukocytes (Lieschke et al., 2001), and molecular ...
... al., 2001). Whether zebrafish eosinophils are the functional orthologues of these cells remains to be determined. Surveys with toluidine blue, a stain for the metachromatic granules of mammalian mast cells, failed to identify any positively staining leukocytes (Lieschke et al., 2001), and molecular ...
Lymphopoiesis
Lymphopoiesis (lĭm'fō-poi-ē'sĭs) (or lymphocytopoiesis) is the generation of lymphocytes, one of the five types of white blood cell (WBC). It is more formally known as lymphoid hematopoiesis.Pathosis in lymphopoiesis leads to any of various lymphoproliferative disorders, such as the lymphomas and lymphoid leukemias.