1 - Universitas Brawijaya
... together to form a “single” functional protein Functional proteins also might incorporate minerals or other nonprotein components ...
... together to form a “single” functional protein Functional proteins also might incorporate minerals or other nonprotein components ...
Clinical Synopsis A 32year old female presented with a four year
... may develop from these melanocytes that have escaped immune destruction. The mechanisms of immune escape are not clearly known but Le Poole et al9 hypothesized that the tumor escape may be due to early activation of T-cells secreting IFN-α which contribute to tumor escape and development of vitiligo ...
... may develop from these melanocytes that have escaped immune destruction. The mechanisms of immune escape are not clearly known but Le Poole et al9 hypothesized that the tumor escape may be due to early activation of T-cells secreting IFN-α which contribute to tumor escape and development of vitiligo ...
Janeway`s Immunology - Cal State LA
... to the arm of an antibody molecule with the TCR a-chain representing the light chain and the b-chain the heavy chain. • T cell recognize digested peptide presented through MHC molecules. ...
... to the arm of an antibody molecule with the TCR a-chain representing the light chain and the b-chain the heavy chain. • T cell recognize digested peptide presented through MHC molecules. ...
Platelets stimulate airway smooth muscle cell proliferation through mechanisms
... Cells (both ASMC and platelet) were thereafter washed three times with ice-cold PBS and lysed by incubation in RIPA buffer supplemented with 1 mM phenylmethanesulfonyl fluoride, 20 μM leupeptin, 1 μM pepstatin for 5 min on ice. Cellular extracts were thereafter heated to 90 ˚C for 10 min. The amount ...
... Cells (both ASMC and platelet) were thereafter washed three times with ice-cold PBS and lysed by incubation in RIPA buffer supplemented with 1 mM phenylmethanesulfonyl fluoride, 20 μM leupeptin, 1 μM pepstatin for 5 min on ice. Cellular extracts were thereafter heated to 90 ˚C for 10 min. The amount ...
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... circulating blood and underlying tissue. The endothelium is also a source of components necessary for the normal functioning of the cardiovascular system ( a ...
... circulating blood and underlying tissue. The endothelium is also a source of components necessary for the normal functioning of the cardiovascular system ( a ...
Decision-making critical amino acids: role in designing peptide
... Apart from the cytokines, other factors may also selectively control the development of Th1 and Th2 cells. It has been reported that p–MHC interactions also specifically influence the differentiation of naı̈ve CD4 T cell to either Th1 or Th2 cells (Kumar et al. 1995). Nevertheless, there is a strong ...
... Apart from the cytokines, other factors may also selectively control the development of Th1 and Th2 cells. It has been reported that p–MHC interactions also specifically influence the differentiation of naı̈ve CD4 T cell to either Th1 or Th2 cells (Kumar et al. 1995). Nevertheless, there is a strong ...
requirements for memory b cell and long lived plasma cell
... immunological memory, which protects against re-infection. Memory B and T cells are longlived, antigen-specific cells with the capacity to mount rapid and expanded responses upon secondary exposure to antigens or pathogens [1]. Memory responses form the basis of vaccination and protection from re-ex ...
... immunological memory, which protects against re-infection. Memory B and T cells are longlived, antigen-specific cells with the capacity to mount rapid and expanded responses upon secondary exposure to antigens or pathogens [1]. Memory responses form the basis of vaccination and protection from re-ex ...
(pdf)
... to thousands of years, then depending upon the temperature, individual cells should persist long enough for the ...
... to thousands of years, then depending upon the temperature, individual cells should persist long enough for the ...
Taurine 10 sample chapter
... 1.3.1 Taurine supplementation increases the size and number of the Islets of Langerhans In this study we examined the effects of taurine supplementation on pancreatic remodeling. Mice were supplemented with taurine (0.05%) in drinking water at the age of four weeks and remained on this diet for an a ...
... 1.3.1 Taurine supplementation increases the size and number of the Islets of Langerhans In this study we examined the effects of taurine supplementation on pancreatic remodeling. Mice were supplemented with taurine (0.05%) in drinking water at the age of four weeks and remained on this diet for an a ...
αII-Spectrin interacts with Tes and EVL, two actin
... Two-hybrid screening was performed as described in [10], using the αII-spectrin sequence (accession number U83867) from Asp885 to Leu1229 as baits. This sequence corresponding to repeat units α9-α10, including or not including the 20-residue insert, named αII1 and αII2 respectively, was cloned int ...
... Two-hybrid screening was performed as described in [10], using the αII-spectrin sequence (accession number U83867) from Asp885 to Leu1229 as baits. This sequence corresponding to repeat units α9-α10, including or not including the 20-residue insert, named αII1 and αII2 respectively, was cloned int ...
Lymphocytic hypophysitis: a rare or underestimated disease?
... cases it can induce acute secondary hyposurrenalism as the first appearance of the disease, with high mortality of affected patients (27, 71). LYH can also cause thyrotropin (TSH) and/or gonadotropin deficiencies (which are usually misdiagnosed when LYH affects women in pregnancy or in the postpartu ...
... cases it can induce acute secondary hyposurrenalism as the first appearance of the disease, with high mortality of affected patients (27, 71). LYH can also cause thyrotropin (TSH) and/or gonadotropin deficiencies (which are usually misdiagnosed when LYH affects women in pregnancy or in the postpartu ...
Immune response on rabbit does of different genetic
... this thesis was to study the immune response of rabbit does of different genetic types subjected to reproductive, environment and immunologic challenges, and its relationship with body condition. Effect of selection was studied using different genetic types. Three studies were carried out: In the fi ...
... this thesis was to study the immune response of rabbit does of different genetic types subjected to reproductive, environment and immunologic challenges, and its relationship with body condition. Effect of selection was studied using different genetic types. Three studies were carried out: In the fi ...
Sensitivity of plant mitochondrial terminal oxidases to the lipid
... the Aox and Cox pathways of respiration. Mitochondria were incubated for 20 min with increasing concentrations of HNE (0– 700 µM), prior to measuring oxygen consumption with succinate as substrate in the presence of ADP, to maximize electron donation to the respiratory chain. The Aox inhibitor n-PG ...
... the Aox and Cox pathways of respiration. Mitochondria were incubated for 20 min with increasing concentrations of HNE (0– 700 µM), prior to measuring oxygen consumption with succinate as substrate in the presence of ADP, to maximize electron donation to the respiratory chain. The Aox inhibitor n-PG ...
Glyceraldehyde-3-Phosphate Dehydrogenase Is a GABAA Receptor
... luminescence (Amersham Biosciences, Buckinghamshire, UK). Recombinant proteins were purified from the cytosolic extracts on a nickelchelating HisTrap column (Amersham Biosciences, Uppsala, Sweden) and followed-up by fluorescence. The direct phosphorylation assay with the fusion proteins was the same ...
... luminescence (Amersham Biosciences, Buckinghamshire, UK). Recombinant proteins were purified from the cytosolic extracts on a nickelchelating HisTrap column (Amersham Biosciences, Uppsala, Sweden) and followed-up by fluorescence. The direct phosphorylation assay with the fusion proteins was the same ...
ABSTRACT Title of Document:
... Figure 1-2. The TLR9 signaling pathway in B cells......................................................... 27 Figure 2-1. Differential effects of CpG DNA on proliferation of lymphoma B cell line and primary B cells. .................................................................................... ...
... Figure 1-2. The TLR9 signaling pathway in B cells......................................................... 27 Figure 2-1. Differential effects of CpG DNA on proliferation of lymphoma B cell line and primary B cells. .................................................................................... ...
Immune mechanisms in Borrelia burgdorferi sensu lato
... The hypothesis of this thesis was that a strong inflammatory Th1-like immune response is required in the early stage of infection in order to achieve both an optimal eradication of the B. burgdorferi s.l. bacteria and a good clinical outcome. The inflammatory response must be down-regulated by an an ...
... The hypothesis of this thesis was that a strong inflammatory Th1-like immune response is required in the early stage of infection in order to achieve both an optimal eradication of the B. burgdorferi s.l. bacteria and a good clinical outcome. The inflammatory response must be down-regulated by an an ...
Autoimmune Hemolytic Anemia and Red Blood Cell Autoantibodies
... albumin instead of low ionic-strength solutions because some cold RBC autoantibodies are enhanced by low ionicstrength solutions.5 Warm-reacting IgG RBC autoantibodies tend to cause all panel and autocontrol RBCs to agglutinate after incubation at 378C and the addition of AHG. Because all panel cel ...
... albumin instead of low ionic-strength solutions because some cold RBC autoantibodies are enhanced by low ionicstrength solutions.5 Warm-reacting IgG RBC autoantibodies tend to cause all panel and autocontrol RBCs to agglutinate after incubation at 378C and the addition of AHG. Because all panel cel ...
Gene Section CDC25A (cell division cycle 25A) Atlas of Genetics and Cytogenetics
... breast cancer cell lines it was reported that CDC25A overexpression is mainly due to increased protein stability as oppose to gene amplification or transcriptional upregulation. - In mice, overexpression of CDC25A alone in mammary gland using mouse mammary tumor virus (MMTV) promoter, is not suffici ...
... breast cancer cell lines it was reported that CDC25A overexpression is mainly due to increased protein stability as oppose to gene amplification or transcriptional upregulation. - In mice, overexpression of CDC25A alone in mammary gland using mouse mammary tumor virus (MMTV) promoter, is not suffici ...
Identification of the Human Erythrocyte Glucose Transporter (GLUT1
... facilitative glucose transporters selectively pump ...
... facilitative glucose transporters selectively pump ...
Final Program - Cancer Research Institute
... activation of those T cells requires that an additional signal be delivered concurrently. These additional signals can result from the enhanced expression of costimulatory molecules, including CD80 and CD86 on APCs triggered by adjuvants, such as microbial products or CD40 ligation, among others. Th ...
... activation of those T cells requires that an additional signal be delivered concurrently. These additional signals can result from the enhanced expression of costimulatory molecules, including CD80 and CD86 on APCs triggered by adjuvants, such as microbial products or CD40 ligation, among others. Th ...
Food Lectins in Health and Disease: An Introduction
... glycoprotein or glycolipid. They typically agglutinate certain animal cells and/or precipitate glycoconjugates. Lectins serve many different biological functions in animals, from the regulation of cell adhesion to glycoprotein synthesis and the control of protein levels in the blood. They may also b ...
... glycoprotein or glycolipid. They typically agglutinate certain animal cells and/or precipitate glycoconjugates. Lectins serve many different biological functions in animals, from the regulation of cell adhesion to glycoprotein synthesis and the control of protein levels in the blood. They may also b ...
Biochemistry 499
... Reversible phosphorylation of proteins is known to be a method of regulation of many cellular pathways. The enzymes involved in the reactions in reversible phosphorylation are protein kinases, which catalyze phosphorylation, and protein phosphatases, which catalyze dephosphorylation. Protein phospha ...
... Reversible phosphorylation of proteins is known to be a method of regulation of many cellular pathways. The enzymes involved in the reactions in reversible phosphorylation are protein kinases, which catalyze phosphorylation, and protein phosphatases, which catalyze dephosphorylation. Protein phospha ...
The Ostrich (Struthio camelus) egg
... (groupe U - 1 1 6 ) . T h e excellent technical assist a n c e of Mrs. M. BERGER (purification of the e n z y m e a n d analyses) a n d of Mr. L v QUAN LE ( a u t o m a t e d E d m a n d e g r a d a t i o n ) is gratefully a c k n o w l e d g e d by the authors. T h e latter express also their t h a ...
... (groupe U - 1 1 6 ) . T h e excellent technical assist a n c e of Mrs. M. BERGER (purification of the e n z y m e a n d analyses) a n d of Mr. L v QUAN LE ( a u t o m a t e d E d m a n d e g r a d a t i o n ) is gratefully a c k n o w l e d g e d by the authors. T h e latter express also their t h a ...
Identification and Analysis of Dicer Associated Proteins in
... cells and co-immunoprecipitating proteins were analyzed by mass spectrometry. Proteins identified to specifically co-purify with Dicer fall into different categories: (1) known components of RNA silencing pathways, such as Argonaute proteins; (2) translation factors; (3) RNA helicases; (4) RNA bindi ...
... cells and co-immunoprecipitating proteins were analyzed by mass spectrometry. Proteins identified to specifically co-purify with Dicer fall into different categories: (1) known components of RNA silencing pathways, such as Argonaute proteins; (2) translation factors; (3) RNA helicases; (4) RNA bindi ...
Licentiate thesis from the Department of Immunology,
... lytic enzymes in the lysosome 34; apoptosis 24 of infected macrophages which removes the niche for growth and therefore restricts multiplication of bacteria. ...
... lytic enzymes in the lysosome 34; apoptosis 24 of infected macrophages which removes the niche for growth and therefore restricts multiplication of bacteria. ...
Monoclonal antibody
Monoclonal antibodies (mAb or moAb) are monospecific antibodies that are made by identical immune cells that are all clones of a unique parent cell, in contrast to polyclonal antibodies which are made from several different immune cells. Monoclonal antibodies have monovalent affinity, in that they bind to the same epitope.Given almost any substance, it is possible to produce monoclonal antibodies that specifically bind to that substance; they can then serve to detect or purify that substance. This has become an important tool in biochemistry, molecular biology and medicine. When used as medications, the non-proprietary drug name ends in -mab (see ""Nomenclature of monoclonal antibodies""), and many immunotherapy specialists use the word mab anacronymically.