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Title: Co-expression of urokinase-type plasminogen activator and its
Title: Co-expression of urokinase-type plasminogen activator and its

... and u-PAR as well as MMP-2, but not MMP-9. This cell line was both tumorigenic and highly invasive (51.3 +/- 13.1%) on a modified CAM, Its invasive capacity was comparable with that of a highly malignant human epidermoid-carcinoma cell line (HEp3), which usually showed 40 to 50% invasiveness, The 3 ...
The Immune System
The Immune System

... T cell receptors bind to antigens on antigen presenting cells (AHCs) on their major histocompatibilty complex molecules (MHCs). MHCs: proteins that are the product of gene groups. Class I MHCs are on all body cells except for red blood cells. Class II MHCs are made by B cells, macrophages, and dendr ...
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... These “Memory” cells will divide QUICKLY and produce more antibodies if they come in contact with that pathogen again. ANTIBODIES are effective against microbes (microscopic organisms) that appear ...
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... secreting an enzyme called lysozyme 2. Eosinophils – remove toxins & defend the body from allergic reactions by producing antihistamines 3. Basophils – play a role in body’s inflammatory response; produce histamine (vasodilator) & heparin (anticoagulant) ...
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... as part of the immune response to antigenic challenge by any foreign substance. Antibodies are commonly characterized as either monoclonal or polyclonal. Monoclonal antibodies are immunoglobins raised against a particular portion of the antigen called an epitope catalytically and can be used to inve ...
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Monoclonal antibody



Monoclonal antibodies (mAb or moAb) are monospecific antibodies that are made by identical immune cells that are all clones of a unique parent cell, in contrast to polyclonal antibodies which are made from several different immune cells. Monoclonal antibodies have monovalent affinity, in that they bind to the same epitope.Given almost any substance, it is possible to produce monoclonal antibodies that specifically bind to that substance; they can then serve to detect or purify that substance. This has become an important tool in biochemistry, molecular biology and medicine. When used as medications, the non-proprietary drug name ends in -mab (see ""Nomenclature of monoclonal antibodies""), and many immunotherapy specialists use the word mab anacronymically.
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