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PowerPoint® format
PowerPoint® format

... A. Vaccine contain antigens (weakened or dead virus, bacteria that cause disease). When enter the body, antigens stimulate the immune system (B cells to produce antibodies with help of T cells). B. The antibodies are produced to fight the weakened or dead viruses in the vaccine. C. The antibodies “p ...
Chapter 16 Supplement
Chapter 16 Supplement

... It has been stated that “boosting your immune system is the single most important thing you can do for your health.” Students interested in learning how to improve their immune system should read The Immune Advantage: The Powerful, Natural Immune-Boosting Program to Help You Prevent Disease, Enhance ...
Immunology - Biology - Missouri State University
Immunology - Biology - Missouri State University

... Autoimmunity • Autoimmunity results when the immune system responds to self-components – tolerance usually protects an individual – protection is through clonal anergy or clonal suppression ...
Discovery of potent inhibitors of the epigenetic cancer target PRMT4
Discovery of potent inhibitors of the epigenetic cancer target PRMT4

... favorable microenvironment for tumor growth and metastasis [5]. It is reported overexpressed in prostate [6], colorectal [7] and in aggressive breast cancers [8]. To this date, few PRMT4 inhibitors have been discovered among which EPZ011652 is an example [9]. Unfortunately, EPZ011652, similarly to o ...
The Immune System
The Immune System

... YouTube Clip: Types of White Blood Cells (lymphocytes) from the BBC ...
Blood Cell Development
Blood Cell Development

... Pre-processing occurs during mid and late fetal life, as well as after birth After exposure to antigens, the B-lymphocytes make antibodies specific to the antigen On subsequent exposure to the antigen, the Blymphocytes secrete an antibody ...
REVIEWS
REVIEWS

... In addition, the use of antibodies as therapeutic reagents has the advantage that there are several isotypes, which can function therapeutically in either an intact form or as fragments. In the intact molecule, the variable region (Fab) binds antigen, whereas the constant region (Fc) determines the ...
Chapter 43 Power Point notes
Chapter 43 Power Point notes

...  A, B, AB, and O blood groups  A red blood cells have A antigens on their surface and make antibodies against the B antigen. ...
Project name: Release of Neutrophil Extracellular Traps (NETs) in
Project name: Release of Neutrophil Extracellular Traps (NETs) in

... NETs may act serving as effective antimicrobial defenses, but also as putative sources of molecules that induce inflammation and may promote tissue damage. Deficient NET formation predisposes humans to severe infection, while uncontrolled NET formation contributes to inflammation, vascular injury an ...
Slide 1
Slide 1

... • Vaccines composed of bacterial polysaccharide antigens: flu, pneumococcus ...
Allergy
Allergy

... hours. A positive skin test indicates that the person has been infected with the agent, but it does not confirm the presence of current disease. However, if the skin test converts from negative to positive, it suggests that the patient has been recently infected. Cell-mediated hypersensitivity devel ...
T-cell Recognition/Antigen presentation
T-cell Recognition/Antigen presentation

... parasites? WThere and when is it decided whether a naïve T-cell is going to develop into a TH1, TH2, Th17 effector cell? Cytokine microenvironment: (IL12, IFNy, IL4, IL1-6 need to know no more yet) , List the so-called “signature cytokines” of the various Th cell populations! ...
radioimmunoassay - OldForensics 2012-2013
radioimmunoassay - OldForensics 2012-2013

... •Lately it has been replaced by the ELISA method which uses Colorimetric signals instead of radioactive signals. But the RIA method still remains the most consistent and low priced. •The technique was developed by Rosalyn Yalow and Soloman Aaron Berson, in the 1950s. •In 1977 Yalow won the Nobel Pri ...
organ
organ

... • Vaccines can be administered by a needle, mouth and some thorough a nasal spray. • In the US children are vaccinated before they can enter school for: Measles, Mumps, Rubella, Pertussis, Hepatitis B, Diphtheria, and Tetanus ...
Powerpoint Presentation of Viruses, HIV, & AIDS
Powerpoint Presentation of Viruses, HIV, & AIDS

... gp 120 locks to cell’s CD4 protein HIV injects RNA into CD4 cell. Reverse transcriptase produces DNA from RNA. Viral DNA embeds in cell’s DNA in ...
Document
Document

... know function of helper T cells, cytotoxic T cells, memory T cells, effector or plasma B cells , memory B cells, macrophages, dendritic cells know how Helper T cells (TH) regulate entire immune system know what monoclonal antibodies are what what immunity is, difference between active and passive im ...
穨 bio
穨 bio

... (A)Transposons have a specific target site within the genome. (B)Transposons are found in both prokaryotes and eukaryotes. (C)Transposons can move from a plasmid to the chromosome of the bacterium. (D)Transposons may replicate at the original site and insert the copy at another site. (E)Transposons ...
Teaching Slides
Teaching Slides

... Each lymphocyte bears one specific type of receptor. Receptor/antigen binding is required for cell activation. Activated lymphocytes divide and give rise to cells with identical receptors to the parent. – This is how your immune system “remembers” a pathogen later! ...
Unbinding forces of single antibody-antigen
Unbinding forces of single antibody-antigen

... Unbinding forces of single antibodyantigen complexes correlate with their thermal dissociation rates Schwesinger et al, 2000 ...
3 pharmacy B cells
3 pharmacy B cells

... Expression of Fc receptors on the cell surface is constitutive (relativelly) Different cells express various Fc receptors Antibodies with diferent izotype activates distinct cells, effector functions ...
The Immune System
The Immune System

... Neutralization: immune complex formation blocks specific sites on virus or toxin & prohibit binding to tissues Agglutination: cells are crosslinked by immune complexes & clump together Precipitation: soluble molecules (such as toxins) are crosslinked, become insoluble, & precipitate out of the solut ...
Molecularly defined vaccines and clinical immunotherapies
Molecularly defined vaccines and clinical immunotherapies

... inferred transcription factors and predicted target genes that are consistently modulated in at least two out of three datasets, with the third dataset not being contradictory. Modular immune in vitro construct system ...
+ the statement is correct - the statement isn´t correct 1. Out of the
+ the statement is correct - the statement isn´t correct 1. Out of the

... 1) - Neutrophils survive in the connective tissue for several weeks 2) - Average size of an erythrocyte is 9 µm 3) - Central part of platelets containing coagulation factors is called a hyalomere 4) + Eosinophilia (increased number of eosinophils in blood) is associated with allergic reactions and p ...
Document
Document

... • The antibodies damage cells and tissues by activating complement and by binding and activating Fc receptor + effector cells ...
Chapter 17b
Chapter 17b

... • Hybridomas are produced by fusing a cancer cell with an Ab-secreting plasma cells • The hybridoma cell culture is immortal and produces monoclonal Abs (Mabs) • Immunotoxins: Mabs conjugated with a toxin to target cancer cells • Chimeric Mabs: Genetically modified mice that produce Ab with a human ...
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Monoclonal antibody



Monoclonal antibodies (mAb or moAb) are monospecific antibodies that are made by identical immune cells that are all clones of a unique parent cell, in contrast to polyclonal antibodies which are made from several different immune cells. Monoclonal antibodies have monovalent affinity, in that they bind to the same epitope.Given almost any substance, it is possible to produce monoclonal antibodies that specifically bind to that substance; they can then serve to detect or purify that substance. This has become an important tool in biochemistry, molecular biology and medicine. When used as medications, the non-proprietary drug name ends in -mab (see ""Nomenclature of monoclonal antibodies""), and many immunotherapy specialists use the word mab anacronymically.
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