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Ensemble Patterns of Hippocampal CA3
Ensemble Patterns of Hippocampal CA3

... 1989), processing of information occurs during macroscopic oscillations (Buzsaki and Chrobak, 1995). Studying the contribution of the individual hippocampal regions to the overall performance is difficult during oscillatory states because oscillations tend to synchronize all neurons in the circuit. ...
Comparison of population coherence of place cells in hippocampal
Comparison of population coherence of place cells in hippocampal

... two regions6–13, there have been few reports of robust differences in the firing properties of CA1 and CA3 neurons in behaving animals. The most extensively studied of these properties is the spatially selective firing of hippocampal ‘place cells’1,14. Here we report that in a dynamically changing e ...
Functional Connectivity of the Secondary Somatosensory Cortex of
Functional Connectivity of the Secondary Somatosensory Cortex of

... provide an alternative view, that is, S2 received direct thalamic inputs rather than through a serially organized path by means of S1. One hypothesis to explain these divergent findings is the possibility that serial or parallel processing types vary among species and/ or different body regions. The ...
Distribution of neurons in functional areas of the mouse cerebral
Distribution of neurons in functional areas of the mouse cerebral

... Examining the distribution of neurons across functional areas requires well-established criteria for identifying and isolating these areas. Such criteria have been established in the most widely used mouse brain atlas, in which the cerebral cortex has been segmented by careful comparison of cytoarch ...
morphological changes in chick embryo neural tissue associated
morphological changes in chick embryo neural tissue associated

... almost no cellular structure. Both concentrations of hydrocortisone indicated cell death associated with apoptosis and necrosis. In vitro studies using primary cultures of chick neurons indicated that hydrocortisone is non-toxic at low concentrations (26.3nM – 3.8M) with the percentage viability ra ...
Focal local field potential (LFP) signature of the single
Focal local field potential (LFP) signature of the single

... connections from single thalamocortical (TC) neurons impinging onto neuronal populations in cortical layer 4 (Swadlow et al., 2002) as illustrated schematically in Figure 1A. Layer 4 is considered to be the major gateway into cortex of sensory information relayed by the thalamus (Bruno and Sakmann, ...
Receptor Tyrosine Kinases: Molecular Switches Regulating CNS
Receptor Tyrosine Kinases: Molecular Switches Regulating CNS

... Although, the absolute signalling mechanisms underlying injured ON axon growth inhibition are not well understood, several studies indicate that axon regeneration is at least partially compromised by the activation of EGFR-mediated signalling pathways in association with myelin-derived inhibitory cu ...
Focal local field potential (LFP) signature of the single
Focal local field potential (LFP) signature of the single

... connections from single thalamocortical (TC) neurons impinging onto neuronal populations in cortical layer 4 (Swadlow et al., 2002) as illustrated schematically in Figure 1A. Layer 4 is considered to be the major gateway into cortex of sensory information relayed by the thalamus (Bruno and Sakmann, ...
Seventeen
Seventeen

Novel approaches to explore mechanisms of
Novel approaches to explore mechanisms of

... Epilepsy comprises a family of neurological disorders characterized by recurrent seizures, which can be highly debilitating. Up to 30% of patients with temporal lobe epilepsy, the most common form of the disorder in adults, arising in the hippocampus, cannot be effectively treated by current pharmac ...
Trigeminal Ganglion Cell Processes Are
Trigeminal Ganglion Cell Processes Are

... of the whiskers is transferred to afferent arbors and their target cells along the entire trigeminal neuraxis leading to the neocortex. In this study, we present evidence of an orderly patterning in the early outgrowth of trigeminal ganglion cell processes; this intrinsic spatial organization may pr ...
University of Birmingham Drosophila neurotrophins reveal a
University of Birmingham Drosophila neurotrophins reveal a

... also control cell proliferation and neuronal differentiation, and they are required for axonal and dendritic elaborations, synaptic plasticity, excitability, and long-term potentiation (LTP, the basis of memory and learning) [2–5]. NTs underlie most aspects of vertebrate nervous system development a ...
The Structure and Plasticity of the Proximal Axon of Hippocampal
The Structure and Plasticity of the Proximal Axon of Hippocampal

... importance for neuronal physiology as it maintains axonal identity and generates action potentials. The AIS is regarded as a highly stable structure comprised by remarkably long-lived molecules, with the exception of Ankyrin-G (AnkG). However, multipolar neurons regulate their intrinsic excitability ...
theta oscillation in the hippocampus
theta oscillation in the hippocampus

... within the D100–200 ms range. The cellular-synaptic generation of theta activity in the hippocampus was investigated by intracellular recordings from the somata and dendrites of CA1 pyramidal cells in urethaneanesthetized rats. The recorded neurons were verified by intracellular injection of biocyti ...
GABA transporters in the mammalian cerebral cortex - LIRA-Lab
GABA transporters in the mammalian cerebral cortex - LIRA-Lab

... asymmetric synaptic contacts with cell bodies or dendrites, or are close to neuronal profiles that do not form synaptic contacts in the plane of section [143]. In surgical samples of human cerebral cortex, GAT-3 ir is found throughout its depth in puncta as well as neurons [139]. GAT-3+ puncta are b ...
The time of course of BDNF levels in brain and plasma after cerebral
The time of course of BDNF levels in brain and plasma after cerebral

... where it is stored and released from neurons in a use-dependent fashion and has been implicated in long term potentiation, learning and memory formation (Greenberg et al., 2009; Nagappan and Lu, 2005). BDNF also represents a crucial signalling molecule in adaptative brain plasticity after stroke (Co ...
Central Neuropeptide Y Signaling Ameliorates N
Central Neuropeptide Y Signaling Ameliorates N

... Abstract—Neuropeptide Y is a potent inhibitory neurotransmitter expressed in the central neurons that control blood pressure. NO also serves as an inhibitory neurotransmitter, and its deficit causes sympathetic overactivity, which then contributes to hypertension. This study tested the hypothesis th ...
Receptores Monoaminérgicos en Corteza Prefrontal: Mecanismo de Acción de Fármacos Antipsicóticos
Receptores Monoaminérgicos en Corteza Prefrontal: Mecanismo de Acción de Fármacos Antipsicóticos

... NMDA receptor (NMDA-R) antagonists are extensively used as schizophrenia models due to their ability to evoke positive and negative symptoms as well as cognitive deficits similar to those of the illness. Cognitive deficits in schizophrenia are associated with prefrontal cortex (PFC) abnormalities. T ...
Neurotransmitter Profile of Saccadic Omnipause Neurons in
Neurotransmitter Profile of Saccadic Omnipause Neurons in

... University of Munich, 80337 Munich, zDepartment of Zoology and Neurobiology, ...
repo
repo

... Ak/Y ; UAS Gal80ts, D::E/ Sco; F gal4, UAS RFP/ TM6b, Tb X Ak/ FM7; ∆B; P{EP}C/ TM3, Act GFP, Ser http://flybase.org/static_pages/docs/nomenclature/nomenclature3.html ...
The neuronal structure of the medial geniculate body in the pig
The neuronal structure of the medial geniculate body in the pig

... the multipolar, pear-shaped, triangular and single fusiform neurons whereas in the medial division (in the same order of frequency) the multipolar, fusiform, triangular and pear-shaped neurons are observed. On the basis of the cytoarchitectonic data the round, spindle-shaped, triangular and multipol ...
THESIS D - Krishikosh
THESIS D - Krishikosh

... and well wishes, I want to preserve a special love for my relatives and well wishers, which enable me to complete the entire research program successfully. I would always remember the invaluable help, active cooperation and constant inspiration of my wife Dr. Sanjivani and my lovely son Arjun who ma ...
189084_189084 - espace@Curtin
189084_189084 - espace@Curtin

... only important from an anatomical point of view, but would assist interpretations of the many experiments performed in mouse models of Parkinson‟s disease, particularly as there is a selective loss mainly of the ventral A9 neurons in this disease (Ma et al. 1995; Pakkenberg et al. 1991). The observa ...
Mapping the Brain
Mapping the Brain

Circadian Plasticity of Mammalian Inhibitory Interneurons
Circadian Plasticity of Mammalian Inhibitory Interneurons

... Many aspects of mammalian behavior and physiology show circadian rhythmicity. The circadian rhythms, with a period about a day (circa, around and dies, day), are generated by the central clock or pacemaker that in mammals is located in suprachiasmatic nuclei (SCN) of the hypothalamus. Under day/nigh ...
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Subventricular zone



The subventricular zone (SVZ) is a paired brain structure situated throughout the lateral walls of the lateral ventricles. It is composed of four distinct layers of variable thickness and cell density, as well as cellular composition. Along with the dentate gyrus of the hippocampus, the SVZ is one of two places where neurogenesis has been found to occur in the adult mammalian brain.
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