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On the Nucleotide Sequence of Yeast Tyrosine Transfer RNA
On the Nucleotide Sequence of Yeast Tyrosine Transfer RNA

... tyrosine acceptor activity and ultraviolet absorbance curves coincide fairly well. The tyrosine acceptor specific activity decreasing on the left side of the peak probably means that there is another RNA that distributes just behind the tyrosine tRNA. The best indication of the purity of the tyrosin ...
13-1 Changing the Living World
13-1 Changing the Living World

... DNA can be extracted from most cells by a simple chemical procedure. The cells are opened and the DNA is separated from the other cell parts. ...
Enzyme Structure
Enzyme Structure

... temperature (i.e. it's a curve, not a straight line). The rate increases because the enzyme and substrate molecules both have more kinetic energy so collide more often, and also because more molecules have sufficient energy to overcome the (greatly reduced) activation energy. The increase in rate wi ...
Regulation of GFP Expression
Regulation of GFP Expression

... pieces of DNA called plasmids. Plasmid DNA usually contains genes for one or more traits that may be beneficial to bacterial survival. In nature, bacteria can transfer plasmids back and forth, allowing them to share these beneficial genes. This natural mechanism allows bacteria to adapt to new envir ...
here - Genomes Unzipped
here - Genomes Unzipped

... genomes have been sequenced at low coverage [2], and identified 10,210 sites of mismatches between an individual’s mRNA and DNA sequences (RDD sites, for RNA-DNA difference). RDD sites included all possible combinations of sequence mismatches, and the authors validated a subset of these mismatches b ...
Generative Power and Closure Properties of Watson
Generative Power and Closure Properties of Watson

... in fundamental way, to solve wide spectrum of computationally intractable problems. DNA (deoxyribonucleic acid) is double-stranded chain of nucleotides, which differ by their chemical bases that are adenine (A), guanine (G), cytosine (C), and thymine (T), and they are paired as A-T, C-G according to ...
Mutation, Mutagens, and DNA Repair
Mutation, Mutagens, and DNA Repair

... genes coding for any of these proteins will interfere with the process and cause the mutant bacterium to be highly sensitive to killing and mutation by UV light. The excision repair system probably repairs a large amount of UV damage. In yeast and other eukaryotes, DNA is wrapped up in more complica ...
oL-Amylase of Clostridium thermosulfurogenes EMi:
oL-Amylase of Clostridium thermosulfurogenes EMi:

... enzymatically functioning regions. The tentative Ca2+-binding site (consensus region I) of this Ca2+independent enzyme showed only limited homology. The deduced amino acid sequence of a second obviously truncated open reading frame showed significant homology to the malG gene product of E. coli. Com ...
Lecture 3 Natural Selection on Behavior 4 slides per page
Lecture 3 Natural Selection on Behavior 4 slides per page

... 1. Natural selection acts on individuals, but its consequences occur in populations (e.g. mean phenotype of the population changes). 2. Natural selection acts on phenotypes, but evolution consists of changes in allele frequencies. 3. Evolution is not forward looking. Adaptation is based on past sele ...
BMS 6204 MEDICAL BIOCHEMISTRY & GENETICS SPRING 2010
BMS 6204 MEDICAL BIOCHEMISTRY & GENETICS SPRING 2010

... 3.6 ATP: Do I really want that second serving of pasta? Let's do the math (anaerobic vs. aerobic) 3.7 Glucose Storage: glycogenesis/glycogenolysis Small groups (3.1) 3.8 Gluconeogenesis: Glucogenic and ketogenic amino acids Muscle Metabolism: Cori cycle 3.9 Urea Synthesis and Metabolism Q & A with L ...
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Lecture 3 Natural Selection on Behavior 1 slide per page

... 1. Natural selection acts on individuals, but its consequences occur in populations (e.g. mean phenotype of the population changes). 2. Natural selection acts on phenotypes, but evolution consists of changes in allele frequencies. 3. Evolution is not forward looking. Adaptation is based on past sele ...
spectroscopic studies of mosquito iridescent virus, its capsid
spectroscopic studies of mosquito iridescent virus, its capsid

... at low temperatures make it possible to distinguish the DNA viruses from the RNA ones [3–5]. It has been confirmed that the energy structures of DNA, RNA, and complex protein macromolecules are determined mainly by the individual properties of their π-electron systems, such as aromatic amino acids ( ...
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poster_CSHL_2007

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C454_lect12 - chem.uwec.edu - University of Wisconsin
C454_lect12 - chem.uwec.edu - University of Wisconsin

pdf file - The Department of Computer Science
pdf file - The Department of Computer Science

... elementary syntheses. Only in the lines 28 and 31 the first activities of this kind appear (enolase and CTP synthase), followed by other enzymes involved in the synthesis of RNA monomers. The primacy of RNA in early evolution has long been an accepted view. But where are the enzymes synthesizing ami ...
Lecture 12 - Nucleotide Biosynthesis - chem.uwec.edu
Lecture 12 - Nucleotide Biosynthesis - chem.uwec.edu

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... (1) and which we have estimated to be in the range of 77% in our study. Integration of several datasets is the first choice to increase the coverage as has been recently demonstrated by our group (2). Here, we present an integrated network of DNA metabolism for T. pallidum, which is solely based on ...
Genetics, environment and cognitive abilities
Genetics, environment and cognitive abilities

... Another exciting direction for research is to identify specific genes responsible for the substantial heritability of g. Heritability of complex dimensions such as g seems likely to be due to multiple genes of varying, but small, effect size rather than one or a few genes with major effect. In such ...
Pearson science 10 Teaching Program 3–4 weeks Chapter 1 DNA
Pearson science 10 Teaching Program 3–4 weeks Chapter 1 DNA

...  evaluating information from secondary sources as part of the research process  developing ideas from students’ own or others' investigations and experiences to investigate further PLANNING AND CONDUCTING Plan, select and use appropriate investigation methods, including field work and laboratory e ...
review - Sonoma Valley High School
review - Sonoma Valley High School

... 3. Of what importance are lactic acid fermentation and alcoholic fermentation to the cells that use these pathways? ___________________________________ _______________________________________________________________ 4. Critical Thinking The vitamin niacin is an essential component of NAD+. Niacin ca ...
Translation - clemson.edu
Translation - clemson.edu

... 16. What happens when the ribosome reads the next codon after the start codon? _________________________________________________________________ 17. What kind of bond forms between the two amino acids? ___________________ 18. As the ribosome moves along the mRNA strand, what happens to the first tRN ...
Y Chromosome Markers
Y Chromosome Markers

... – Determine Paternal Lineage ...
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Deoxyribozyme



Deoxyribozymes, also called DNA enzymes, DNAzymes, or catalytic DNA, are DNA oligonucleotides that are capable of catalyzing specific chemical reactions, similar to the action of other biological enzymes, such as proteins or ribozymes (enzymes composed of RNA).However, in contrast to the abundance of protein enzymes in biological systems and the discovery of biological ribozymes in the 1980s,there are no known naturally occurring deoxyribozymes.Deoxyribozymes should not be confused with DNA aptamers which are oligonucleotides that selectively bind a target ligand, but do not catalyze a subsequent chemical reaction.With the exception of ribozymes, nucleic acid molecules within cells primarily serve as storage of genetic information due to its ability to form complementary base pairs, which allows for high-fidelity copying and transfer of genetic information. In contrast, nucleic acid molecules are more limited in their catalytic ability, in comparison to protein enzymes, to just three types of interactions: hydrogen bonding, pi stacking, and metal-ion coordination. This is due to the limited number of functional groups of the nucleic acid monomers: while proteins are built from up to twenty different amino acids with various functional groups, nucleic acids are built from just four chemically similar nucleobases. In addition, DNA lacks the 2'-hydroxyl group found in RNA which limits the catalytic competency of deoxyribozymes even in comparison to ribozymes.In addition to the inherent inferiority of DNA catalytic activity, the apparent lack of naturally occurring deoxyribozymes may also be due to the primarily double-stranded conformation of DNA in biological systems which would limit its physical flexibility and ability to form tertiary structures, and so would drastically limit the ability of double-stranded DNA to act as a catalyst; though there are a few known instances of biological single-stranded DNA such as multicopy single-stranded DNA (msDNA), certain viral genomes, and the replication fork formed during DNA replication. Further structural differences between DNA and RNA may also play a role in the lack of biological deoxyribozymes, such as the additional methyl group of the DNA base thymidine compared to the RNA base uracil or the tendency of DNA to adopt the B-form helix while RNA tends to adopt the A-form helix. However, it has also been shown that DNA can form structures that RNA cannot, which suggests that, though there are differences in structures that each can form, neither is inherently more or less catalytic due to their possible structural motifs.
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