Dictionary of Interfaces in Proteins (DIP). Data Bank of
... substances, up to 2 kDa, are generally found to be small curved pockets (Peters et al., 1996), in contrast with interacting surfaces between two proteins, which are quite ¯at (Jones & Thornton, 1996). Until now the geometric properties of interacting pieces of secondary structures have not been desc ...
... substances, up to 2 kDa, are generally found to be small curved pockets (Peters et al., 1996), in contrast with interacting surfaces between two proteins, which are quite ¯at (Jones & Thornton, 1996). Until now the geometric properties of interacting pieces of secondary structures have not been desc ...
De Novo Mutation Found in the Porphobilinogen Deaminase Gene
... codon after 36 completely different amino acids compared to the original sequence. To further confirm the mutation, we proceeded to RFLP. Pursuant to which the identified mutation caused loss of the restriction endonuclease recognition site. The 317-kb fragment of genomic DNA containing exon 15 and ...
... codon after 36 completely different amino acids compared to the original sequence. To further confirm the mutation, we proceeded to RFLP. Pursuant to which the identified mutation caused loss of the restriction endonuclease recognition site. The 317-kb fragment of genomic DNA containing exon 15 and ...
Course Home - Haldia Institute of Technology
... including prediction and modeling to different Biochemical reactions, with an understanding of the limitations FT401.5: Ability to communicate effectively on professional activities with the engineering community to function effectively as an individual or leader in diverse teams in multi-disciplina ...
... including prediction and modeling to different Biochemical reactions, with an understanding of the limitations FT401.5: Ability to communicate effectively on professional activities with the engineering community to function effectively as an individual or leader in diverse teams in multi-disciplina ...
Chapter 2 - University of the Free State
... •At higher salt concentrations, weak interactions between the disordered water molecules are further disrupted, i.e., the molecules become even less ordered •transfer of a water molecule from the ordered environment next to the hydrophobic droplet to the disordered state, will have a larger ∆S compo ...
... •At higher salt concentrations, weak interactions between the disordered water molecules are further disrupted, i.e., the molecules become even less ordered •transfer of a water molecule from the ordered environment next to the hydrophobic droplet to the disordered state, will have a larger ∆S compo ...
Ch. 13 end of chapter review
... 24. A chromosomal mutation that occurs during meiosis will be carried by some of the organism’s gametes and possibly to the organism’s offspring. A mutation that occurs during mitosis in a body cell will be passed on to that cell’s daughter cells but not to the organism’s offspring. 25. The mutation ...
... 24. A chromosomal mutation that occurs during meiosis will be carried by some of the organism’s gametes and possibly to the organism’s offspring. A mutation that occurs during mitosis in a body cell will be passed on to that cell’s daughter cells but not to the organism’s offspring. 25. The mutation ...
The Calcium-Binding Activity of a Vacuole
... membranes, VCaB45 was readily proteolysed to a smaller size by proteinase K (at higher concentrations of protease VCaB45 was completely degraded; data not shown). The purified VCaB45 was also susceptible to proteinase K digestion (data not shown). However, in the absence of detergent, the insensitiv ...
... membranes, VCaB45 was readily proteolysed to a smaller size by proteinase K (at higher concentrations of protease VCaB45 was completely degraded; data not shown). The purified VCaB45 was also susceptible to proteinase K digestion (data not shown). However, in the absence of detergent, the insensitiv ...
24.9 Synthesis of Amino Acids
... Overview, Metabolism Catabolic pathways • degrade large molecules. • form small molecules that enter the citric acid cycle and electron transport to produce energy. Anabolic pathways • use small molecules and energy. • synthesize larger molecules in the cell. In the overall view of metabolism, ther ...
... Overview, Metabolism Catabolic pathways • degrade large molecules. • form small molecules that enter the citric acid cycle and electron transport to produce energy. Anabolic pathways • use small molecules and energy. • synthesize larger molecules in the cell. In the overall view of metabolism, ther ...
Domain organization of human cleavage factor Im 1 Distinct
... Eukaryotic messenger RNA precursors (pre-mRNAs) are synthesized and processed in the nucleus prior to their export to the cytoplasm, where they serve as templates for protein synthesis. Transcription is coupled spatially and temporally to capping of the premRNA at the 5’!end, splicing and 3’!end for ...
... Eukaryotic messenger RNA precursors (pre-mRNAs) are synthesized and processed in the nucleus prior to their export to the cytoplasm, where they serve as templates for protein synthesis. Transcription is coupled spatially and temporally to capping of the premRNA at the 5’!end, splicing and 3’!end for ...
Phenylpropanoids
... to make perfumes and flavorings. It is also used to prepare other chemicals -- in particular anticoagulants and rodent poison. Coumarin is found in a variety of plants such as Tonka bean, lavender, sweet clover grass, and licorice, but also occurs in food plants such as strawberries, apricots, cherr ...
... to make perfumes and flavorings. It is also used to prepare other chemicals -- in particular anticoagulants and rodent poison. Coumarin is found in a variety of plants such as Tonka bean, lavender, sweet clover grass, and licorice, but also occurs in food plants such as strawberries, apricots, cherr ...
The molecules of life - Breakthrough Science Society
... endless diversity of the protein molecules is the basis of the chemistry of life. Such variations have made it possible to evolve different protein molecules for different activities of our body. Moreover, there is obviously no limit to the generation of new variety every day. The function of differ ...
... endless diversity of the protein molecules is the basis of the chemistry of life. Such variations have made it possible to evolve different protein molecules for different activities of our body. Moreover, there is obviously no limit to the generation of new variety every day. The function of differ ...
Amyloid deposits - Lindquist Lab
... In summary, while the particular misfolded proteins vary in these diseases, in all three cases protein deposits are a poor indicator of neuronal loss. This makes it plausible that structured protein deposits help cells to cope with misfolded proteins. In turn, the failure of particular neurons to cr ...
... In summary, while the particular misfolded proteins vary in these diseases, in all three cases protein deposits are a poor indicator of neuronal loss. This makes it plausible that structured protein deposits help cells to cope with misfolded proteins. In turn, the failure of particular neurons to cr ...
GAG binding proteins
... Inactivates proteases involved in coagulation (Factors IIa and Xa) Blocks coagulation Antithrombin deficiency results in thrombosis (clot formation) ...
... Inactivates proteases involved in coagulation (Factors IIa and Xa) Blocks coagulation Antithrombin deficiency results in thrombosis (clot formation) ...
70-74 Research Article Molecular Docking Studies of Deacetylbisaco
... enzyme and result in a clinically relevant drug interaction with a substrate for the enzyme. Ki is reflective of the binding affinity. If a Ki is much larger than the maximal plasma drug concentrations a patient is exposed to from typical dosing, then that drug is not likely to inhibit the activity ...
... enzyme and result in a clinically relevant drug interaction with a substrate for the enzyme. Ki is reflective of the binding affinity. If a Ki is much larger than the maximal plasma drug concentrations a patient is exposed to from typical dosing, then that drug is not likely to inhibit the activity ...
BCHM 463 Supplemental Problems for Friday, April 9, 2004 1. a
... 7. Compare the relative efficiencies (in ATP’s per glucose oxidized) of glucose oxidation via glycolysis + the citric acid cycle vs. glucose oxidation via the pentose phosphate pathway + glycolysis. (Assume that NADH and NADPH are each equivalent to three ATPs and that FADH is equivalent to 2 ATPs.) ...
... 7. Compare the relative efficiencies (in ATP’s per glucose oxidized) of glucose oxidation via glycolysis + the citric acid cycle vs. glucose oxidation via the pentose phosphate pathway + glycolysis. (Assume that NADH and NADPH are each equivalent to three ATPs and that FADH is equivalent to 2 ATPs.) ...
Ion exchange chromatography
... Bauman as a new analytical method. In 1979, Fritz et al. described an alternative separation and detection scheme for inorganic anions, in which the separator column is directly coupled to the conductivity cell. At the end of the 1970s, ion chromatographic techniques were used to analyze organic ion ...
... Bauman as a new analytical method. In 1979, Fritz et al. described an alternative separation and detection scheme for inorganic anions, in which the separator column is directly coupled to the conductivity cell. At the end of the 1970s, ion chromatographic techniques were used to analyze organic ion ...
Enzymes in Food Technology
... range of cereal-basedrecipes without changing the taste and appearance of the final product. • Asparaginase has been shown to work in both hard and short doughs, and at temperatures between 10°C and 40°C. • Acrylamide reduction of 50-90% was seen for the different recipes and process parameters. • F ...
... range of cereal-basedrecipes without changing the taste and appearance of the final product. • Asparaginase has been shown to work in both hard and short doughs, and at temperatures between 10°C and 40°C. • Acrylamide reduction of 50-90% was seen for the different recipes and process parameters. • F ...
Mechanisms of Cellular injury
... • Increased susceptibility to respiratory infections, especially Staphylcoccus aureus, Pseudomonas and Burkholderi aeruginosa which are almost impossible to eliminate – Loss of ionic concentrations – Loss of antimicrobial peptide (defensin activity) – CFTR a receptor for Pseudomonas ...
... • Increased susceptibility to respiratory infections, especially Staphylcoccus aureus, Pseudomonas and Burkholderi aeruginosa which are almost impossible to eliminate – Loss of ionic concentrations – Loss of antimicrobial peptide (defensin activity) – CFTR a receptor for Pseudomonas ...
Protein-nucleic acid interactions
... The helix-turn-helix (HTH) motif — roughly 20 amino acids folded into two roughly perpendicular α-helices linked by a β-turn or loop — is used by transcription regulators and enzymes of both prokaryotes and eukaryotes typically to bind the major-groove edges of the DNA base pairs. The linker and non ...
... The helix-turn-helix (HTH) motif — roughly 20 amino acids folded into two roughly perpendicular α-helices linked by a β-turn or loop — is used by transcription regulators and enzymes of both prokaryotes and eukaryotes typically to bind the major-groove edges of the DNA base pairs. The linker and non ...
13059_2010_2366_MOESM1_ESM
... [27] showed numerous genes of likely red algal origin in the Phytophthora genomes, in common with the heterokont algae, Thalassiosira pseudonana (a diatom). Analysis of the genome of T. pseudonana showed that a high proportion of genes had homology with proteins of A. thaliana [5]. Bowler et al. [6] ...
... [27] showed numerous genes of likely red algal origin in the Phytophthora genomes, in common with the heterokont algae, Thalassiosira pseudonana (a diatom). Analysis of the genome of T. pseudonana showed that a high proportion of genes had homology with proteins of A. thaliana [5]. Bowler et al. [6] ...
Enzyme Hydrolyzed Collagen Protein
... proteins to make up hair, muscles, nails, tendons, ligaments, and other body structures such as body fluids; but not bile or urine. Proteins also function as enzymes, hormones, and as important components of other cells such as our genes. The central nervous system cannot function without protein – ...
... proteins to make up hair, muscles, nails, tendons, ligaments, and other body structures such as body fluids; but not bile or urine. Proteins also function as enzymes, hormones, and as important components of other cells such as our genes. The central nervous system cannot function without protein – ...
SuccFind: a novel succinylation sites online
... 3 Results and discussion Based on the succinylation data sets, we firstly generated the graphical sequence logo (P < 0.01; t-test) and detected a statistically significant differences in position-specific symbol compositions and biochemical environment (Fig. 1a, Supplementary Fig. S1). We then calcu ...
... 3 Results and discussion Based on the succinylation data sets, we firstly generated the graphical sequence logo (P < 0.01; t-test) and detected a statistically significant differences in position-specific symbol compositions and biochemical environment (Fig. 1a, Supplementary Fig. S1). We then calcu ...
1.1-IMS-CHEM.Macromolecules
... • Amino acids (20 different kinds of “aa”) bonded together by peptide bonds (polypeptides). ...
... • Amino acids (20 different kinds of “aa”) bonded together by peptide bonds (polypeptides). ...
Proteolysis
Proteolysis is the breakdown of proteins into smaller polypeptides or amino acids. Uncatalysed, the hydrolysis of peptide bonds is extremely slow, taking hundreds of years. Proteolysis is typically catalysed by cellular enzymes called proteases, but may also occur by intra-molecular digestion. Low pH or high temperatures can also cause proteolysis non-enzymatically.Proteolysis in organisms serves many purposes; for example, digestive enzymes break down proteins in food to provide amino acids for the organism, while proteolytic processing of a polypeptide chain after its synthesis may be necessary for the production of an active protein. It is also important in the regulation of some physiological and cellular processes, as well as preventing the accumulation of unwanted or abnormal proteins in cells. Consequently, dis-regulation of proteolysis can cause diseases, and is used in some venoms to damage their prey.Proteolysis is important as an analytical tool for studying proteins in the laboratory, as well as industrially, for example in food processing and stain removal.