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AQA A-level Biology
AQA A-level Biology

... to make many other carbohydrates. Two α-glucose molecules join by condensation to form a molecule of the disaccharide maltose. The bond forms between carbon 1 of one α-glucose molecule and carbon 4 of the other, and is called a glycosidic bond (see Figure 1.5). Other disaccharides form in a similar ...
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... or absorbed pancreatic proteases, before absorption [19, 201. In contrast to the results of the perfusions with LH1, 13 residues were absorbed at similar rates from LH2 and its free amino acid mixture and the remaining four were actually absorbed faster from the amino acid mixture. The most likely r ...
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... Advantages of DT40 cells for our studies: centrosomal proteins are very stable; siRNA does not offer a good option centrosome proteins are large and modular; DT40 offers a system to study specific domains the majority of centrosomal proteins are not essential; knockouts survive little is known abou ...
Membrane Adaptation and Solute Uptake Systems
Membrane Adaptation and Solute Uptake Systems

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Proteolysis



Proteolysis is the breakdown of proteins into smaller polypeptides or amino acids. Uncatalysed, the hydrolysis of peptide bonds is extremely slow, taking hundreds of years. Proteolysis is typically catalysed by cellular enzymes called proteases, but may also occur by intra-molecular digestion. Low pH or high temperatures can also cause proteolysis non-enzymatically.Proteolysis in organisms serves many purposes; for example, digestive enzymes break down proteins in food to provide amino acids for the organism, while proteolytic processing of a polypeptide chain after its synthesis may be necessary for the production of an active protein. It is also important in the regulation of some physiological and cellular processes, as well as preventing the accumulation of unwanted or abnormal proteins in cells. Consequently, dis-regulation of proteolysis can cause diseases, and is used in some venoms to damage their prey.Proteolysis is important as an analytical tool for studying proteins in the laboratory, as well as industrially, for example in food processing and stain removal.
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