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DNA Microarray - Montana State University
DNA Microarray - Montana State University

... What we will be discussing…  What is DNA microarray?  The purpose of using DNA microarray.  The plate.  Steps to perform a microarray. ...
US Supreme Court Holds That Isolated Human DNA is Not Patent
US Supreme Court Holds That Isolated Human DNA is Not Patent

... The Court addressed (1) whether a naturally occurring segment of DNA is eligible for patenting “by virtue of its isolation from the rest of the human genome”; and (2) whether synthetically created DNA known as complementary DNA (cDNA), “which contains the same protein-coding information found in a s ...
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A1988L264200002

... methylase that would postreplicationally form 5’-methylcytosine at symmetrical DNA sites. It was further proposed that thisenzyme would prefer hemimethylated sites. With such an enzyme, methylation patterns would be somatically heritable and could be important for X-chromosome inactivation and cellu ...
chapter outline - McGraw Hill Higher Education
chapter outline - McGraw Hill Higher Education

... 3. The purine adenine (A) on one strand of DNA is always paired (through hydrogen bonds) with the pyrimidine thymine (T) on the other strand, while the purine guanine (G) is always paired with the pyrimidine cytosine (C); thus, the two strands are said to be complementary 4. The two strands are not ...
Unit 2
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RNA Metabolism Summary Slides as Questions

... 20. How are ribosomal RNA genes first transcribed? Then what happens to them? They are first transcribed as a cluster, then methylated and cleaved by Rnases into the mature products. These rRNAs are stable, have a “Svedberg number” based on size, are very complex with Watson-Crick duplexes. 21. What ...
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... codon - sequence of three nucleotides in DNA or mRNA that specifies a particular amino acid during protein synthesis; also called triplet. Of the 64 possible codons, three are stop codons, which do not specify amino acids complementary DNA (cDNA) - DNA that is synthesized in the laboratory from a me ...
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Nucleic acid analogue



Nucleic acid analogues are compounds which are analogous (structurally similar) to naturally occurring RNA and DNA, used in medicine and in molecular biology research.Nucleic acids are chains of nucleotides, which are composed of three parts: a phosphate backbone, a pucker-shaped pentose sugar, either ribose or deoxyribose, and one of four nucleobases.An analogue may have any of these altered. Typically the analogue nucleobases confer, among other things, different base pairing and base stacking properties. Examples include universal bases, which can pair with all four canonical bases, and phosphate-sugar backbone analogues such as PNA, which affect the properties of the chain (PNA can even form a triple helix).Nucleic acid analogues are also called Xeno Nucleic Acid and represent one of the main pillars of xenobiology, the design of new-to-nature forms of life based on alternative biochemistries.Artificial nucleic acids include peptide nucleic acid (PNA), Morpholino and locked nucleic acid (LNA), as well as glycol nucleic acid (GNA) and threose nucleic acid (TNA). Each of these is distinguished from naturally occurring DNA or RNA by changes to the backbone of the molecule.In May 2014, researchers announced that they had successfully introduced two new artificial nucleotides into bacterial DNA, and by including individual artificial nucleotides in the culture media, were able to passage the bacteria 24 times; they did not create mRNA or proteins able to use the artificial nucleotides. The artificial nucleotides featured 2 fused aromatic rings.
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