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information transfer in life - The Origin and Evolution of Life
information transfer in life - The Origin and Evolution of Life

... figure 3.7. Note that RNA is a single strand, whereas DNA is double stranded. Also note the RNA does not contain the chemical thymine. Another chemical called uracil replaces it. Thus, an A-U bond (adenine-uracil) is formed between the DNA and RNA strand (as opposed to adenine-thymine). The enzyme R ...
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Amino Acid Substitution - UNT's College of Education

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ASTR 380 The Origins of Life on Earth
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... Hypothesis that RNA were the first self-reproducing molecules. There were capable of making themselves and proteins Later evolved to make DNA, and later evolved into DNA dominated world. ...
Applications Lecture 4 - Rose
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... individual proteins. (the production of these proteins is known as gene expression) b. Gene expression takes place in two stages i. Transcription—DNA is turned into RNA via the enzyme RNA polymerase. ii. Translation—RNA is turned into Protein in the rough Endoplasmic Reticulum found in the cytoplasm ...
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... Predicting the start and end of genes as well as the introns and exons in each gene is one of the basic problems in computational biology. Gene prediction methods look for ORFs (Open ...
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... Figure 1.1) is an important simple sugar molecule with the chemical formula C6 H12 O6 . Simple sugars are known as monosaccharides. Carbohydrates also include long chains of connected sugar molecules. These long chains often consist of hundreds or thousands of monosaccharides bonded together to form ...
MOLECULAR TECHNIQUES
MOLECULAR TECHNIQUES

... http://avery.rutgers.edu/WSSP/StudentScholars/project/archives/onions/rapd.html ...
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... • testing for a pathogenic mutation in a certain gene in an individual that indicate a person’s risk of developing or transmitting a disease • Used for mutation screening of disease genes e.g. HD, CFTR, DMD ...
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... these chromosomes have over autosomes for these types of studies. 1. No recombination 2. paternal or maternal inheritance 3. high copy number for mtDNA 2. Androgen insensitivity is an X-linked trait that results from the inability to respond to testosterone and dihydroxytestosterone. Describe the ka ...
2004 Lec 42-43: Nucleotide Metabolism
2004 Lec 42-43: Nucleotide Metabolism

... No part of this presentation may be reproduced by any mechanical, photographic, or electronic process, or in the form of a phonographic recording, nor may it be stored in a retrieval system, transmitted, or otherwise copied for public or private use, without written permission from the publisher. ...
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...  Built a model of the double helix that conformed to the others’ research 1. two outside strands consist of alternating deoxyribose and phosphate 2. cytosine and guanine bases pair to each other by three hydrogen bonds 3. thymine and adenine bases pair to each other by two hydrogen bonds ...
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... • DNA consists of two long interwoven strands that form the famous “double helix”. Each Strand is built from a small set of molecules called nucleotides. • Often the length of double-stranded DNA is expressed in the units of basepairs (bp), kilobasepairs (kb), or megabasepairs (Mb), so that this siz ...
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... Types of RNA 1. mRNA carries the genetic “message” from the nucleus to the cytosol 2. rRNA is the major component of ribosomes 3. tRNA carries specific amino acids, helping to form polypeptides (proteins) ...
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... DNA is arranged in a double helix – has 2 strands and twists like a ladder Replication – process in which DNA makes a copy of itself – it unzips and free bases attach following the base pair rule. DNA holds the code for the making of proteins needed for life. Three bases in a row is a codon that cod ...
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Whippo - cloudfront.net

... All vertebrates have genes that make hemoglobin Like many other genes, hemoglobin genes mutates at a fairly constant rate, even if they are in different animal groups Rate of change can be used to estimate how long ago groups or organisms diverged from one another! ...
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Nucleic acid analogue



Nucleic acid analogues are compounds which are analogous (structurally similar) to naturally occurring RNA and DNA, used in medicine and in molecular biology research.Nucleic acids are chains of nucleotides, which are composed of three parts: a phosphate backbone, a pucker-shaped pentose sugar, either ribose or deoxyribose, and one of four nucleobases.An analogue may have any of these altered. Typically the analogue nucleobases confer, among other things, different base pairing and base stacking properties. Examples include universal bases, which can pair with all four canonical bases, and phosphate-sugar backbone analogues such as PNA, which affect the properties of the chain (PNA can even form a triple helix).Nucleic acid analogues are also called Xeno Nucleic Acid and represent one of the main pillars of xenobiology, the design of new-to-nature forms of life based on alternative biochemistries.Artificial nucleic acids include peptide nucleic acid (PNA), Morpholino and locked nucleic acid (LNA), as well as glycol nucleic acid (GNA) and threose nucleic acid (TNA). Each of these is distinguished from naturally occurring DNA or RNA by changes to the backbone of the molecule.In May 2014, researchers announced that they had successfully introduced two new artificial nucleotides into bacterial DNA, and by including individual artificial nucleotides in the culture media, were able to passage the bacteria 24 times; they did not create mRNA or proteins able to use the artificial nucleotides. The artificial nucleotides featured 2 fused aromatic rings.
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