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MUTATION, DNA REPAIR AND CANCER
MUTATION, DNA REPAIR AND CANCER

... undamaged strand is used as a template for resynthesis of a normal complementary strand ...
MUTATION, DNA REPAIR AND CANCER
MUTATION, DNA REPAIR AND CANCER

... undamaged strand is used as a template for resynthesis of a normal complementary strand ...
Basic Chemistry
Basic Chemistry

... electrons are transferred from one atom to another. These positively and negatively charged atoms are known as ions. Ionic bonds are common in salts. ...
Recent progress in understanding transcription factor binding
Recent progress in understanding transcription factor binding

... understanding and predicting gene regulatory network function. Transcription factors typically belong to a structural family containing many other proteins with a similar amino acid sequence. Even when the difference in nucleotide sequence preference between such proteins is subtle, their target gen ...
Reg Bio DNA tech 2013 ppt
Reg Bio DNA tech 2013 ppt

... purposes (use DNA technology) - identify genes for specific traits - transfer genes from one organism to another ...
*Exam3 2015 key Revised
*Exam3 2015 key Revised

... C) messenger RNA. D) plasmid. E) yeast “ARS” sequence. Circle the correct answer. 34. [2 points] The PCR reaction mixture does not include: A) oligonucleotide primer(s). B) all four deoxynucleoside triphosphates. C) DNA containing the sequence to be amplified. D) DNA ligase. E) heat-stable DNA polym ...
Content Domain One: Cells
Content Domain One: Cells

... 2. A type of mutation that can alter DNA by the loss of a nucleotide base is known as A substitution B crossing over C deletion D insertion 3. In Mendel’s experiments with a single trait, the trait that disappeared in the first Generation and reappeared in the next generation is called the A homozyg ...
SBI3U Genetics Review
SBI3U Genetics Review

... DNA: Structure and Function -be able to describe the structure of DNA (double helix, nitrogen bases: A,C,T,G, sugar-phosphate backbone) (p614) -know that DNA is the genetic code or sequence that provides instructions on how to build proteins. -proteins are long chains of amino acids that perform sp ...
File
File

... are the same in all DNA molecules, but the rungs are what makes the variation. • Each rung is made up of a pair of chemicals called guanine, cytosine, thymine, adenine. • A always bonds with T • G always bonds with C ...
Genes and Genetic Disease
Genes and Genetic Disease

... Principle of segregation– homologous genes separate, reproductive cells carry only one gene (meiosis) Principle of independent assortment – hereditary transmission of one gene does not affect the transmission of another. ...
Explain hyperventilation and hypoventilation in terms of
Explain hyperventilation and hypoventilation in terms of

... 1. Relationship between the structural features of water and its unique chemical properties: a. Features: Water (H2O) has a bent structure, which makes it polar. It is a H bond donor and acceptor. It has the potential to form four H bonds per water, but liquid water averages only 2.3 H bonds. (We do ...
Beyond Mendel: Molecular genetics, cell division, and sex
Beyond Mendel: Molecular genetics, cell division, and sex

... 10-6 m), the 46 pieces would total about 750 kilometers long (450 miles)! − at this scale, single genes would range from 2 cm (less than 1 inch) long to about 75 meters (244 feet, or 81 yards) long − (500 codons x 3 bases/codon x 3.4 angstroms/base, to 2 million codons) − DNA has an unusual structur ...
RNA-Seq - iPlant Pods
RNA-Seq - iPlant Pods

... All honeybees begin as worker bees, flying short distances. Some honeybees transition into foragers, flying long distances. This transition necessitates major changes in flight muscles. Goal is to identify the gene expression changes in flight muscles during this transition ...
Messenger RNA
Messenger RNA

... • A master plan has all the information needed to construct a building – DNA. • Blueprints are inexpensive, disposable copies of the master plan – RNA. • The DNA molecule stays safely in the cell’s nucleus while the RNA molecules go to the protein-building sites in the cytoplasm – the ribosomes. ...
Ch9_DNA-notes
Ch9_DNA-notes

... Franklin and Wilkins • Rosalind Franklin worked in Maurice Wilkins’ lab in the late 1940s, using Xray crystalography to find clues about the structure of DNA. • Franklin’s images were the first to suggest a helical structure. ...
gene regulation
gene regulation

Bio nformatics - City University of New York
Bio nformatics - City University of New York

... • The famous double helix structure was discovered by James Watson and Francis Crick in 1953. • The two strands hold together because each base in one strand bonds to a base in the other. A ↔ T (complementary bases) C ↔ G (complementary bases) ...
genotypes
genotypes

... assemble mRNA. 3. Why is translation necessary? Translation assures that the right amino acids are joined together by peptides to form the correct protein. ...
This would be given at the end of the unit
This would be given at the end of the unit

... 6. Combining genes from different sources into a single DNA molecule is known as a. DNA fingerprinting. b. cloning. c. PCR. d. recombinant DNA technology. 7. Knowing the sequence of an organism’s DNA allows researchers to a. reproduce the organism. b. mutate the DNA. c. study specific genes. d. cut ...
Year 10 Revision
Year 10 Revision

... Karyotyping: During mitosis, the 23 pairs of human chromosomes _________- and are visible with a light microscope. A karyotype analysis usually involves blocking cells in mitosis and staining the condensed chromosomes with dye. The dye stains regions of chromosomes that are rich in the base pairs __ ...
Gene to Protein PowerPoint
Gene to Protein PowerPoint

... from DNA nucleic acid language to RNA nucleic acid language ...
Dairy Jepoardy 3
Dairy Jepoardy 3

... Feedstuffs ...
BI0I 121 cell and tissues
BI0I 121 cell and tissues

... supported the case for proteins as the genetic material. could not be reproduced by other researchers. was an example of conjugation. ...
Genotyping of Transgenic Mice Population
Genotyping of Transgenic Mice Population

From RNA to protein
From RNA to protein

... Functional (transfer) - tRNA Molecules that carry amino acids to the growing polypeptide: ~ 32 different kinds of tRNA in a typical eukaryotic cell • Each is the product of a separate gene. • They are small containing ~ 80 nucleotides. • Double and single stranded regions • The unpaired regions for ...
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Nucleic acid analogue



Nucleic acid analogues are compounds which are analogous (structurally similar) to naturally occurring RNA and DNA, used in medicine and in molecular biology research.Nucleic acids are chains of nucleotides, which are composed of three parts: a phosphate backbone, a pucker-shaped pentose sugar, either ribose or deoxyribose, and one of four nucleobases.An analogue may have any of these altered. Typically the analogue nucleobases confer, among other things, different base pairing and base stacking properties. Examples include universal bases, which can pair with all four canonical bases, and phosphate-sugar backbone analogues such as PNA, which affect the properties of the chain (PNA can even form a triple helix).Nucleic acid analogues are also called Xeno Nucleic Acid and represent one of the main pillars of xenobiology, the design of new-to-nature forms of life based on alternative biochemistries.Artificial nucleic acids include peptide nucleic acid (PNA), Morpholino and locked nucleic acid (LNA), as well as glycol nucleic acid (GNA) and threose nucleic acid (TNA). Each of these is distinguished from naturally occurring DNA or RNA by changes to the backbone of the molecule.In May 2014, researchers announced that they had successfully introduced two new artificial nucleotides into bacterial DNA, and by including individual artificial nucleotides in the culture media, were able to passage the bacteria 24 times; they did not create mRNA or proteins able to use the artificial nucleotides. The artificial nucleotides featured 2 fused aromatic rings.
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