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Genetic Engineering
Genetic Engineering

... • Mice have been produced with human genes that make their immune systems act similarly to those of humans. – Allows scientists to study the effects of diseases on the human ...
The Science of Heredity Chapter Test Genetics
The Science of Heredity Chapter Test Genetics

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... bonds), and G always pairs with C (three hydrogen bonds). Thus, the base sequence on one strand defines the base sequence on the other strand. o Because of the specific base pairing, the amount of A equals the amount of T and the amount of G equals the amount of C. Thus, total purines equals total p ...
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... Heterozygous: situation where the two alleles at a specific genetic locus are not the same. Homologous: stretches of DNA that are very similar in sequence, so similar that they tend to stick together in hybridization experiments. Homologous can also be used to indicate related genes in separate orga ...
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Nucleic acid analogue



Nucleic acid analogues are compounds which are analogous (structurally similar) to naturally occurring RNA and DNA, used in medicine and in molecular biology research.Nucleic acids are chains of nucleotides, which are composed of three parts: a phosphate backbone, a pucker-shaped pentose sugar, either ribose or deoxyribose, and one of four nucleobases.An analogue may have any of these altered. Typically the analogue nucleobases confer, among other things, different base pairing and base stacking properties. Examples include universal bases, which can pair with all four canonical bases, and phosphate-sugar backbone analogues such as PNA, which affect the properties of the chain (PNA can even form a triple helix).Nucleic acid analogues are also called Xeno Nucleic Acid and represent one of the main pillars of xenobiology, the design of new-to-nature forms of life based on alternative biochemistries.Artificial nucleic acids include peptide nucleic acid (PNA), Morpholino and locked nucleic acid (LNA), as well as glycol nucleic acid (GNA) and threose nucleic acid (TNA). Each of these is distinguished from naturally occurring DNA or RNA by changes to the backbone of the molecule.In May 2014, researchers announced that they had successfully introduced two new artificial nucleotides into bacterial DNA, and by including individual artificial nucleotides in the culture media, were able to passage the bacteria 24 times; they did not create mRNA or proteins able to use the artificial nucleotides. The artificial nucleotides featured 2 fused aromatic rings.
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