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Answers to Chapter 1 IQs and RQs
Answers to Chapter 1 IQs and RQs

... For every base pairing, there are three rings between the two strands of DNA. 18. Speculate why a triple-stranded DNA molecule with the negatively charged phosphates in the center would be unstable and thus not a good model. Think of forcing the negative ends of two magnets together. Answering this ...
Background information (includes references for the draft literature
Background information (includes references for the draft literature

... The mutations to p53 listed above are all associated with an increased risk of a wide range of cancers, including colon, breast, head and neck, lung and leukaemia. The reason for this may be explained by examining the location of the mutation in the protein expressed. Location 248 is part of the DN ...
dominant gene
dominant gene

Dr Gisela Storz Biosketch
Dr Gisela Storz Biosketch

... serendipitous  detection  of  the  peroxide-­‐induced  OxyS  RNA,  one  of   the  first  small,  regulatory  RNAs  to  be  discovered,  work  in  her  lab   shifted  to  the  genome-­‐wide  identification  and  study  of  small   RNAs.   ...
Recombinant DNA Technology
Recombinant DNA Technology

... Phages with both ends of the  chormosome and a 37-52 kb insert replicate by infecting E. coli. ...
Cell Biology Workshop I
Cell Biology Workshop I

... R groups for these amino acids, can you compile a few simple rules that would indicate which amino acids are dietary essentials based on their side chain structures and functional groups?  Aromatic groups cannot be made and must be obtained from diet. For example, we cannot synthesize a benzene rin ...
Pantothenic Acid - Pure Encapsulations
Pantothenic Acid - Pure Encapsulations

Structure of Proteins, Carbohydrates and Fats
Structure of Proteins, Carbohydrates and Fats

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... A) to serve as an intermediate in the decoding of genes. * B) to act as transporters bringing amino acids to the site of protein synthesis. C) to serve as general translational components of the ribosome. D) to facilitate splicing of pre-messenger RNAs. E) to facilitate protein trafficking in protei ...
DNA methylation
DNA methylation

... Indeed, specific combinations of histone modifications can alter chromatin structure to allow transcription or to repress it, either reversibly or stably. Chromatin modifications confer a unique identity on the nucleosomes involved. The composite pattern of modifications regulates the binding and ac ...
Fatma El-Sayed Ibrahim Ali_A Symmetric Encryption Algorithm
Fatma El-Sayed Ibrahim Ali_A Symmetric Encryption Algorithm

... According to NIST statistical testing the more randomness binary sequence is the more secrecy it is, but as the final cipher here is presented in a DNA form this rule will be quietly different. Running NIST statistical testing on real DNA sequences; Eight DNA sequences downloaded from NCBI database ...
blood agar base + nalidixic acid
blood agar base + nalidixic acid

... inhibitor of the accompanying flora. Nalidixic acid blocks the DNA replication of susceptible bacteria and acts against many Gram-negative bacteria. The Heart infusion and Meat peptone are rich sources of nitrogen, vitamins, minerals and amino acids essential for growth. Sodium chloride supplies ess ...
Dupont Riboprinter Microbial Characterization System
Dupont Riboprinter Microbial Characterization System

... technicians and lacked standardization and consistency. The RiboPrinter system provides the speed, accuracy, reproducibility and confidence never before possible. From start to finish, the RiboPrinter system process is automated, simplifying operator training and minimizing errors due to technique. ...
Lecture 4 - Biological Molecules Part II
Lecture 4 - Biological Molecules Part II

... • One DNA molecule can be millions of nucleotides long and contain many genes BIOL 211 Winter 2012 ...
Amino Acids 2
Amino Acids 2

... Hydrophobic interactions Hydrogen bonds Ionic interactions ...
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virus - Microbiology

... • Can infect every type of cell • Cannot exist independently from the host cell, so aren’t considered living things • However, since they can direct life processes they are often considered more than lifeless molecules ...
Promega Notes: T4 RNA Ligase: A Molecular Tool for RNA and DNA
Promega Notes: T4 RNA Ligase: A Molecular Tool for RNA and DNA

... amber suppressor tRNA lacking the terminal 3´-CA sequence to a CA dinucleotide that had been chemically modified with an unnatural amino acid. This improvement greatly simplified the original anticodon loop replacement procedure, and they demonstrated that, while lacking post-transcriptional base mo ...
Human Cloning
Human Cloning

... Reproductive cloning is a technology used to generate an animal that has the same nuclear DNA as another currently or previously existing animal In a process called "somatic cell nuclear transfer" (SCNT), scientists transfer genetic material from the nucleus of a donor adult cell to an egg whose nuc ...
Slide 1
Slide 1

... 12.13 Gel electrophoresis sorts DNA molecules by size  Gel electrophoresis can be used to separate DNA molecules based on size as follows: 1. A DNA sample is placed at one end of a porous gel. 2. Current is applied and DNA molecules move from the negative electrode toward the positive electrode. 3 ...
Introduction to the Digestive System Notes
Introduction to the Digestive System Notes

... Liver, Pancreas and Gallbladder • Liver: The center of metabolic activity in the body provides bile salts to the small intestine, which are critical for digestion and absorption of fats. • Pancreas: provides a potent mixture of digestive enzymes to the small intestine which are critical for digesti ...
How was DNA replication shown to be semiconservative.
How was DNA replication shown to be semiconservative.

... DNA replication must have high fidelity. Why? Well, if DNA replication was low fidelity the consequences would be: ...
Sex determination: There are areas in which cattle management
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Interaction of DNA with ribosomes in cell-free protein
Interaction of DNA with ribosomes in cell-free protein

... The concept of protein synthesis of the living cell has been formed and proven after experiments on different types of cells, organs, and organelles. It includes the transcription of the genetic message from the DNA to a messenger RNA and the trans­ lation of the mRNA to polypeptides by the protein ...
PPT poster - Davidson College
PPT poster - Davidson College

... Yes, for a 14-edge graph with 7 nodes, growing 1 billion bacterial computers gives a 99.9% chance of detecting a solution. We determined this using a cumulative Poisson distribution. 1 mL of culture contains 1 billion bacteria. ...
Macromolecules
Macromolecules

... (along with standard Watson-Crick base pairing). The existence of this structure was known for 20 years, but no one knew what to make of it. Now, recognizing that it occurs naturally in gene control regions, it is getting a great deal of attention in the research literature. Currently artificial oli ...
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Nucleic acid analogue



Nucleic acid analogues are compounds which are analogous (structurally similar) to naturally occurring RNA and DNA, used in medicine and in molecular biology research.Nucleic acids are chains of nucleotides, which are composed of three parts: a phosphate backbone, a pucker-shaped pentose sugar, either ribose or deoxyribose, and one of four nucleobases.An analogue may have any of these altered. Typically the analogue nucleobases confer, among other things, different base pairing and base stacking properties. Examples include universal bases, which can pair with all four canonical bases, and phosphate-sugar backbone analogues such as PNA, which affect the properties of the chain (PNA can even form a triple helix).Nucleic acid analogues are also called Xeno Nucleic Acid and represent one of the main pillars of xenobiology, the design of new-to-nature forms of life based on alternative biochemistries.Artificial nucleic acids include peptide nucleic acid (PNA), Morpholino and locked nucleic acid (LNA), as well as glycol nucleic acid (GNA) and threose nucleic acid (TNA). Each of these is distinguished from naturally occurring DNA or RNA by changes to the backbone of the molecule.In May 2014, researchers announced that they had successfully introduced two new artificial nucleotides into bacterial DNA, and by including individual artificial nucleotides in the culture media, were able to passage the bacteria 24 times; they did not create mRNA or proteins able to use the artificial nucleotides. The artificial nucleotides featured 2 fused aromatic rings.
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