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3.2 – Carbohydrates, Lipids and Proteins
3.2 – Carbohydrates, Lipids and Proteins

... sugars. Deoxyribose is a modified version of ribose, and is known for its role in DNA as part of the sugar phosphate backbone. Its chemical properties are very different to ribose. ...
Sequencing genomes
Sequencing genomes

... And the same is true for Dayhoff’s model of evolution. If we need to obtain probability matrices for higher percentage of accepted mutations (i.e. covering longer evolutionary time), we do matrix powers. Let’s say we want PAM120 – 120 mutations fixed on average per 100 residues. We do PAM1120. ...
Deoksyribozymes active in the presence of cadmium ions and at low
Deoksyribozymes active in the presence of cadmium ions and at low

... as well as in biotechnology as specific molecular tools. Nowadays, they are most commonly applied in qualitative and quantitative analysis. Since most DNAzymes require cofactors in the form of divalent metal ions for their catalytic activity, they have been successfully used for construction of bios ...
PPT File
PPT File

... Why is there concern that the avian (bird) flu will be an epidemic in humans? 1. The virus could jump the species barrier. 2. People eat a lot of fried chicken and can get the bird flu by eating it. 3. Birds and humans are very closely related, so we are susceptible to bird diseases. 4. There is no ...
The Structure and Function of Large Biological Molecules
The Structure and Function of Large Biological Molecules

... •  All living things are made up of four classes of large biological molecules: carbohydrates, lipids, proteins, and nucleic acids •  Macromolecules are large molecules composed of thousands of covalently connected atoms •  Molecular structure and function are inseparable ...
August 2007
August 2007

... weakened immune system ...
16. Biotechnology
16. Biotechnology

... are combined/spliced together. ...
Notes
Notes

... ◦ The DNA that codes for a protein (exons) are usually very similar among individuals. ◦ Changing even one base can completely change the shape & function of a protein. ...
Notes
Notes

... ◦ The DNA that codes for a protein (exons) are usually very similar among individuals. ◦ Changing even one base can completely change the shape & function of a protein. ...
Location of Exons in DNA Sequences Using Digital Filters
Location of Exons in DNA Sequences Using Digital Filters

... electron-ion interaction potential values and then filtering the numerical sequence using a narrowband bandpass digital filter whose passband is centered at the period-3 frequency, i.e., 2π/3. The strength of the bandpass-filtered signal as a function of nucleotide location is then detected using a ...
Molecular diagnosis and inborn errors of metabolism
Molecular diagnosis and inborn errors of metabolism

... usually bail one out of a diagnostic dilemma. New disorders may be discovered in this way, but this approach is generally too cost-inefficient to justify routine clinical use, at least under the constraint currently extant in U.S. medicine. The use of DNA analysis has been particularly prevalent in ...
Fig 2. - University of Warwick
Fig 2. - University of Warwick

... Processes which involve the absorption of light play an integral role in our day-to-day lives. Nature has carefully chosen our molecular building blocks so that the potentially devastating effects of ultraviolet radiation are by-passed. Some of the most important molecular building blocks, the DNA b ...
Molecular Biology - Gateway Engineering Education Coalition
Molecular Biology - Gateway Engineering Education Coalition

... You may already know that it is RNA that carries the genetic code to ribosomes with instructions for protein synthesis. Our master DNA tape stays safely away from the action and sends messenger RNA out with the code. One strand of DNA is copied into RNA using RNA polymerase. In order to copy the gen ...
dna - Nutley Public Schools
dna - Nutley Public Schools

... • Polymerase chain reaction is the outgrowth of knowledge gained from an understanding of how DNA strands naturally replicate within a cell. • For the forensic scientist, PCR offers a distinct advantage in that it can amplify minute quantities of DNA many millions of times. • First, the DNA is heate ...
DNA and Mutations Webquest
DNA and Mutations Webquest

... http://evolution.berkeley.edu/evolibrary/article/mutations_01 DNA and Mutations 1. What is a mutation? 2. What does DNA affect? 3. Without mutations, what would not occur? DNA: The molecular basis of mutations 1. What is DNA? 2. What are the four basic units of DNA? 3. The sequence of these bases en ...
Mutation Study Guide
Mutation Study Guide

... A chromosomal mutation typically affects more genes because it takes place at a chromosomal level. Chromosomal mutations can have a large effect and may result in a disrupted gene or abnormal regulation of genes. 6. What is translocation? The attachment of a piece of one chromosome to a non-homologo ...
General enquiries on this form should be made to
General enquiries on this form should be made to

... samples failed to give DNA but extraction from backup samples (collected & freeze dried at the same time as the originals) was successful. The DNA samples were placed in the Warwick HRI freezer archive facility for secure long-term storage. In order to make a strategic resource that can be used for ...
ReeBops
ReeBops

... about all the different parts of a dog. Dogs have fur, eyes, legs, lungs, etc. Dogs are made up of many parts. Think about humans. We have lots of different parts. But do all humans look the same? Do all dogs look the same? Why is there so much variation or differences among species of animals? A ch ...
Understanding Our Environment - McGraw Hill Higher Education
Understanding Our Environment - McGraw Hill Higher Education

... bind specific regulatory proteins to help RNA polymerase attach to its binding site.  Positioning at a distance permits a large number of different regulatory sequences to influence that particular gene. Johnson - The Living World: 3rd Ed. - All Rights Reserved - McGraw Hill Companies ...
Purification of genomic DNA from cultured cells using the
Purification of genomic DNA from cultured cells using the

Biology
Biology

... mutation in the previous question occurs in p53, how many of the cells resulting from mitosis of this cell will carry the mutation? ...
Mechanism of action of trypsin and chymotrypsin
Mechanism of action of trypsin and chymotrypsin

... structurally similar (i.e have similar crystal structure). ...
Chapter 20: Biotechnology
Chapter 20: Biotechnology

... • Most methods for cloning pieces of DNA in the laboratory share general features, such as the use of bacteria and their plasmids • Plasmids are small circular DNA molecules that replicate separately from the bacterial chromosome • Cloned genes are useful for making copies of a particular gene and/o ...
The Chemical Basis of Life Atoms, Molecules, Ions, and Bonds
The Chemical Basis of Life Atoms, Molecules, Ions, and Bonds

Study and engineering of gene function: mutagenesis
Study and engineering of gene function: mutagenesis

... • Obtain mutants that can insert O-methyl-L-tyrosine at any UAG codon ...
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Nucleic acid analogue



Nucleic acid analogues are compounds which are analogous (structurally similar) to naturally occurring RNA and DNA, used in medicine and in molecular biology research.Nucleic acids are chains of nucleotides, which are composed of three parts: a phosphate backbone, a pucker-shaped pentose sugar, either ribose or deoxyribose, and one of four nucleobases.An analogue may have any of these altered. Typically the analogue nucleobases confer, among other things, different base pairing and base stacking properties. Examples include universal bases, which can pair with all four canonical bases, and phosphate-sugar backbone analogues such as PNA, which affect the properties of the chain (PNA can even form a triple helix).Nucleic acid analogues are also called Xeno Nucleic Acid and represent one of the main pillars of xenobiology, the design of new-to-nature forms of life based on alternative biochemistries.Artificial nucleic acids include peptide nucleic acid (PNA), Morpholino and locked nucleic acid (LNA), as well as glycol nucleic acid (GNA) and threose nucleic acid (TNA). Each of these is distinguished from naturally occurring DNA or RNA by changes to the backbone of the molecule.In May 2014, researchers announced that they had successfully introduced two new artificial nucleotides into bacterial DNA, and by including individual artificial nucleotides in the culture media, were able to passage the bacteria 24 times; they did not create mRNA or proteins able to use the artificial nucleotides. The artificial nucleotides featured 2 fused aromatic rings.
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