Mineralocorticoid receptor antagonists for heart failure with reduced
... metalloproteinase 1 (TIMP1), and the MMP1/TIMP1 ratio].28 Compared with baseline, PINP and PIIINP levels were significantly lower at 6 months in patients randomized to spironolactone but not placebo. A hypothesis-generating subgroup analysis based on a small number of patients and events suggested t ...
... metalloproteinase 1 (TIMP1), and the MMP1/TIMP1 ratio].28 Compared with baseline, PINP and PIIINP levels were significantly lower at 6 months in patients randomized to spironolactone but not placebo. A hypothesis-generating subgroup analysis based on a small number of patients and events suggested t ...
AstraZeneca Crestor citizen petition 05 31 2016
... In markets where Crestor® was approved prior to approval of the pediatric orphan drug HoFH sNDA, it is indicated for one or more of the following indications: treatment of patients with primary hypercholesterolemia (heterozygous familial and nonfamilial), mixed dyslipidemia, primary dysbetalipoprote ...
... In markets where Crestor® was approved prior to approval of the pediatric orphan drug HoFH sNDA, it is indicated for one or more of the following indications: treatment of patients with primary hypercholesterolemia (heterozygous familial and nonfamilial), mixed dyslipidemia, primary dysbetalipoprote ...
THE EFFECT OF METAL BASED COMPLEXES ON THE IN VITRO.
... J.C. Swart, verbonde aan die Universiteit van die Oranje Vrystaat het sewentien nuwe iridium, ferrisenium en rodium komplekse verskaf met wat deur my vir sititoksiese aktiewiteit teen die CHO sellyn ondersoek is. Die twee aktiefste komplekse naamlik, [Rh(fctca)(cod)] en [Rh(fctfa)(cod)], is vir moon ...
... J.C. Swart, verbonde aan die Universiteit van die Oranje Vrystaat het sewentien nuwe iridium, ferrisenium en rodium komplekse verskaf met wat deur my vir sititoksiese aktiewiteit teen die CHO sellyn ondersoek is. Die twee aktiefste komplekse naamlik, [Rh(fctca)(cod)] en [Rh(fctfa)(cod)], is vir moon ...
Cardiac Muscle Cells in Culture
... The effect of amiodarone on the expression of myosin isoforms and the growth of neonatal rat cardiac muscle cells in culture was studied by native gel electrophoresis, assays of DNA and protein synthesis, and electron microscopy. Cardiac myocytes exposed to amiodarone in the absence of triiodothyron ...
... The effect of amiodarone on the expression of myosin isoforms and the growth of neonatal rat cardiac muscle cells in culture was studied by native gel electrophoresis, assays of DNA and protein synthesis, and electron microscopy. Cardiac myocytes exposed to amiodarone in the absence of triiodothyron ...
MYRISTICA FRAGRANS NON-FILAMENTOUS Research Article
... Spices have been used since time immemorable as natural preservative for meat, fish etc. a diverse array of natural phytochemicals that have complementary and overlapping actions, including antioxidant effects, modulation of detoxification enzymes, stimulation of immune system, reduction of inflamma ...
... Spices have been used since time immemorable as natural preservative for meat, fish etc. a diverse array of natural phytochemicals that have complementary and overlapping actions, including antioxidant effects, modulation of detoxification enzymes, stimulation of immune system, reduction of inflamma ...
Clinical Implications of Dihydropyrimidine
... in 5-FUsusceptible host tissue, such as gastrointestinal (GI) mucosa and bone marrow, should make dosing from patient to patient less variable, avoiding the typical (with 5-FU and many other cancer chemotherapeutic agents) dosing decisions based on observed toxicity. Inhibition of DPD in tumor spec ...
... in 5-FUsusceptible host tissue, such as gastrointestinal (GI) mucosa and bone marrow, should make dosing from patient to patient less variable, avoiding the typical (with 5-FU and many other cancer chemotherapeutic agents) dosing decisions based on observed toxicity. Inhibition of DPD in tumor spec ...
The new england journal of medicine
... of symptoms during the previous 24 hours. For patients who had an acute coronary syndrome without ST-segment elevation, at least two of the following three criteria had to be met: ST-segment changes on electrocardiography, indicating ischemia; a positive test of a biomarker, indicating myocardial ne ...
... of symptoms during the previous 24 hours. For patients who had an acute coronary syndrome without ST-segment elevation, at least two of the following three criteria had to be met: ST-segment changes on electrocardiography, indicating ischemia; a positive test of a biomarker, indicating myocardial ne ...
British Journal of Nutrition
... following exposure of antigen presenting cells to EPA or DHA(71,72). These findings are supported by work in animals fed fish oil(73), but there is limited information on n-3 PUFAs and antigen presentation in humans(74). ...
... following exposure of antigen presenting cells to EPA or DHA(71,72). These findings are supported by work in animals fed fish oil(73), but there is limited information on n-3 PUFAs and antigen presentation in humans(74). ...
Appendix I 163
... lyophilizate. The freeze-dried homogenized material had been obtained from a 9.6 liter batch of ayahuasca. The DMT content in the lyophilizate had been determined by HPLC, as described by Callaway and coworkers (1996), and the β-carboline constituents following a modification of the method described ...
... lyophilizate. The freeze-dried homogenized material had been obtained from a 9.6 liter batch of ayahuasca. The DMT content in the lyophilizate had been determined by HPLC, as described by Callaway and coworkers (1996), and the β-carboline constituents following a modification of the method described ...
FLONASE (fluticasone propionate) Nasal Spray, 50 mcg
... by signs of adrenal insufficiency, and in addition some patients may experience symptoms of withdrawal, e.g., joint and/or muscular pain, lassitude, and depression. Patients previously treated for prolonged periods with systemic corticosteroids and transferred to topical corticosteroids should be ca ...
... by signs of adrenal insufficiency, and in addition some patients may experience symptoms of withdrawal, e.g., joint and/or muscular pain, lassitude, and depression. Patients previously treated for prolonged periods with systemic corticosteroids and transferred to topical corticosteroids should be ca ...
Albuterol Sulfate Inhalation Solution 0.083%
... monoamine oxidase inhibitors or tricyclic anti-depressants, since the action of albuterol on the vascular system may be potentiated. Beta-receptor blocking agents and albuterol inhibit the effect of each other. Carcinogenesis, Mutagenesis, and Impairment of Fertility: Albuterol sulfate caused a sign ...
... monoamine oxidase inhibitors or tricyclic anti-depressants, since the action of albuterol on the vascular system may be potentiated. Beta-receptor blocking agents and albuterol inhibit the effect of each other. Carcinogenesis, Mutagenesis, and Impairment of Fertility: Albuterol sulfate caused a sign ...
Berinert - CSL Behring
... following administration in patients with HAE. Risk factors may include the presence of an indwelling venous catheter/access device, prior history of thrombosis, underlying atherosclerosis, use of oral contraceptives or certain androgens, morbid obesity, and immobility. Benefits of treatment of HAE ...
... following administration in patients with HAE. Risk factors may include the presence of an indwelling venous catheter/access device, prior history of thrombosis, underlying atherosclerosis, use of oral contraceptives or certain androgens, morbid obesity, and immobility. Benefits of treatment of HAE ...
Amlodipin Bluefish tablet ENG SmPC
... oedema was higher in the amlodipine treated group than in the placebo group (see section 5.1). Calcium channel blockers, including amlodipine, should be used with caution in patients with congestive heart failure, as they may increase the risk of future cardiovascular events and mortality, Use in p ...
... oedema was higher in the amlodipine treated group than in the placebo group (see section 5.1). Calcium channel blockers, including amlodipine, should be used with caution in patients with congestive heart failure, as they may increase the risk of future cardiovascular events and mortality, Use in p ...
strattera - GuildLink
... On average, symptoms of ADHD in STRATTERA-treated patients decreased by 48.5% as measured by the ADHD rating scale total score for study periods II and III. STRATTERA was well tolerated in this long-term safety study and adverse events did not increase over time. The adverse event profile for poor m ...
... On average, symptoms of ADHD in STRATTERA-treated patients decreased by 48.5% as measured by the ADHD rating scale total score for study periods II and III. STRATTERA was well tolerated in this long-term safety study and adverse events did not increase over time. The adverse event profile for poor m ...
Severe asthma and the omalizumab option
... in many patients is driven by an immunoglobulin E (IgE)-dependent process. Mast cell activation and release of mediators, in response to allergen and IgE, results in a cascade response, culminating in B lymphocyte, T lymphocyte, eosinophil, fibroblast, smooth muscle cell and endothelial activation. ...
... in many patients is driven by an immunoglobulin E (IgE)-dependent process. Mast cell activation and release of mediators, in response to allergen and IgE, results in a cascade response, culminating in B lymphocyte, T lymphocyte, eosinophil, fibroblast, smooth muscle cell and endothelial activation. ...
4. concern in the use of naltrexone
... 2. ASSESSMENT Before starting naltrexone for opioid dependent patients take: a detailed history of the heroin dependence a detailed history of other drug use/abuse/dependence examine the patient particularly for clinical signs of recent injections, infections, liver damage. Note any signs of i ...
... 2. ASSESSMENT Before starting naltrexone for opioid dependent patients take: a detailed history of the heroin dependence a detailed history of other drug use/abuse/dependence examine the patient particularly for clinical signs of recent injections, infections, liver damage. Note any signs of i ...
Anabolic Steroids History
... • Usually middle class, heterosexual men with a median age of 25 • 2006 study – 78% noncompetitive bodybuilders and non-athletes (cosmetic) • 13% reported unsafe injection practices (needle sharing) ...
... • Usually middle class, heterosexual men with a median age of 25 • 2006 study – 78% noncompetitive bodybuilders and non-athletes (cosmetic) • 13% reported unsafe injection practices (needle sharing) ...
Reyataz label - HIV Drug Resistance Database
... REYATAZ (atazanavir sulfate) is indicated in combination with other antiretroviral agents for the treatment of HIV-1 infection. This indication is based on analyses of plasma HIV-1 RNA levels and CD4+ cell counts from controlled studies of 96 weeks duration in antiretroviral-naive and 48 weeks durat ...
... REYATAZ (atazanavir sulfate) is indicated in combination with other antiretroviral agents for the treatment of HIV-1 infection. This indication is based on analyses of plasma HIV-1 RNA levels and CD4+ cell counts from controlled studies of 96 weeks duration in antiretroviral-naive and 48 weeks durat ...
Renerve P - SR
... pregabalin, of whom over 5600 were in double-blind placebo-controlled trials. The most commonly reported adverse reactions were dizziness and somnolence. Adverse reactions were usually mild to moderate in intensity. In all controlled studies, the discontinuation rate due to adverse reactions was 12% ...
... pregabalin, of whom over 5600 were in double-blind placebo-controlled trials. The most commonly reported adverse reactions were dizziness and somnolence. Adverse reactions were usually mild to moderate in intensity. In all controlled studies, the discontinuation rate due to adverse reactions was 12% ...
encephalopathy due to prolonged misuse of ivermectin
... of Ivermectin poisoning with severe CNS symptoms have been described in this dogs at therapeutic dose. In human, Ivermectin doesn’t cross the BBB and no central nervous system toxicity has been described at therapeutic dose. However CNS toxicity can occur in acute or chronic overdose. Kong Chung and ...
... of Ivermectin poisoning with severe CNS symptoms have been described in this dogs at therapeutic dose. In human, Ivermectin doesn’t cross the BBB and no central nervous system toxicity has been described at therapeutic dose. However CNS toxicity can occur in acute or chronic overdose. Kong Chung and ...
Prepared By - Beckman Coulter
... All printed copies are considered to be copies of the electronic original. ...
... All printed copies are considered to be copies of the electronic original. ...
Full Product Information
... Special Warnings and Special Precautions for Use Hematologic Effects Serious and fatal blood dyscrasias (aplastic anemia, hypoplastic anemia, thrombocytopenia, granulocytopenia, and bone marrow depression) are known to occur after the administration of chloramphenicol. (See section 4.8 Undesirable E ...
... Special Warnings and Special Precautions for Use Hematologic Effects Serious and fatal blood dyscrasias (aplastic anemia, hypoplastic anemia, thrombocytopenia, granulocytopenia, and bone marrow depression) are known to occur after the administration of chloramphenicol. (See section 4.8 Undesirable E ...
Valproate Learning Objectives Outline Indications
... documented cases from only Germany over 10 years corroborates that the occurrence of this severe side effect is under reported.” ...
... documented cases from only Germany over 10 years corroborates that the occurrence of this severe side effect is under reported.” ...
HIGHLIGHTS OF PRESCRIBING INFORMATION
... than 5 times the upper limit of normal (ULN) occurred in approximately 1% of all subjects [see Adverse Reactions (6.1)]. ALT elevations were typically asymptomatic, occurred during the first 4 weeks of treatment, and declined within two to eight weeks of onset with continued dosing of VIEKIRA PAK wi ...
... than 5 times the upper limit of normal (ULN) occurred in approximately 1% of all subjects [see Adverse Reactions (6.1)]. ALT elevations were typically asymptomatic, occurred during the first 4 weeks of treatment, and declined within two to eight weeks of onset with continued dosing of VIEKIRA PAK wi ...
Leaflet PACKAGE LEAFLET: INFORMATION FOR THE
... - by intramuscular or subcutaneous way: 25 to 50mg, to be repeated if necessary with a maximum dose of 150mg per 24h. - by intravenous way: 10 to 25mg by slow injection to be repeated if necessary after 10 minutes until a maximum amount of 150mg per 24h. For the treatment of a severe acute bronchosp ...
... - by intramuscular or subcutaneous way: 25 to 50mg, to be repeated if necessary with a maximum dose of 150mg per 24h. - by intravenous way: 10 to 25mg by slow injection to be repeated if necessary after 10 minutes until a maximum amount of 150mg per 24h. For the treatment of a severe acute bronchosp ...