Document
... E. Ephedrine 21. A patient with bronchial asthma has been taking isadrinum (isoprenaline) inhalation for a long time. He notices the drug leads to tachycardia and headache. Which agent from listed below can be used instead of isadrinum? A. *Salbutamol B. Mesatonum (phenylephrine) C. Anapriiinum (pro ...
... E. Ephedrine 21. A patient with bronchial asthma has been taking isadrinum (isoprenaline) inhalation for a long time. He notices the drug leads to tachycardia and headache. Which agent from listed below can be used instead of isadrinum? A. *Salbutamol B. Mesatonum (phenylephrine) C. Anapriiinum (pro ...
PRODUCT MONOGRAPH Pr PERIDEX ORAL RINSE
... • Evaluate progress, remove any stain, and reinforce proper home care techniques. • If gingival inflammation and bleeding is controlled, discontinue Peridex therapy and recall the patient in three months to assess gingival health. • If gingival inflammation and bleeding persist, continue Peride ...
... • Evaluate progress, remove any stain, and reinforce proper home care techniques. • If gingival inflammation and bleeding is controlled, discontinue Peridex therapy and recall the patient in three months to assess gingival health. • If gingival inflammation and bleeding persist, continue Peride ...
Memorandum JAN 2 3
... concentrate powder of the dry residue from the extraction of ttil), and Neptune LyO-Krillw (freeze-dried Bill). YOU indicated that the primary source OI all three ingredients is Krill, a shrimp-like crustaceanidentified as Antarctic Krill (species klown as Euphausia superba). h-~ a telephone convers ...
... concentrate powder of the dry residue from the extraction of ttil), and Neptune LyO-Krillw (freeze-dried Bill). YOU indicated that the primary source OI all three ingredients is Krill, a shrimp-like crustaceanidentified as Antarctic Krill (species klown as Euphausia superba). h-~ a telephone convers ...
PRODUCT MONOGRAPH PrLUVOX
... significance] (See ADVERSE REACTIONS). Generally these events are mild to moderate and are self-limiting; however in some patients they may be severe and/or prolonged. They usually occur within the first few days of discontinuing treatment, but there have been very rare reports of such symptoms in p ...
... significance] (See ADVERSE REACTIONS). Generally these events are mild to moderate and are self-limiting; however in some patients they may be severe and/or prolonged. They usually occur within the first few days of discontinuing treatment, but there have been very rare reports of such symptoms in p ...
American Society of Clinical Oncology Guideline for Antiemetics in
... antagonists have equivalent safety and efficacy and can be used interchangeably. 2006 literature update and discussion. There are now at least five agents of this class widely available: dolasetron, granisetron, ondansetron, palonosetron, and tropisetron. Multiple, randomized, controlled studies wit ...
... antagonists have equivalent safety and efficacy and can be used interchangeably. 2006 literature update and discussion. There are now at least five agents of this class widely available: dolasetron, granisetron, ondansetron, palonosetron, and tropisetron. Multiple, randomized, controlled studies wit ...
paracetamol: mechanism of action, applications and safety concern
... In numerous academic textbooks including those published during the last decade, the central mechanism of paracetamol action has been discussed emphasizing its weaker inhibitory effect on the cyclooxygenase activity and prostaglandin production as compared to NSAIDs. The early study by Flower and Va ...
... In numerous academic textbooks including those published during the last decade, the central mechanism of paracetamol action has been discussed emphasizing its weaker inhibitory effect on the cyclooxygenase activity and prostaglandin production as compared to NSAIDs. The early study by Flower and Va ...
Product Monograph Template - Standard - GlaxoSmithKline
... treatment. In most cases, symptoms were reported to resolve after discontinuation of LAMICTAL®. Re-exposure resulted in a rapid return of symptoms (from within 30 minutes to 1 day following re-initiation of treatment) that were frequently more severe. Some of the patients treated with LAMICTAL® who ...
... treatment. In most cases, symptoms were reported to resolve after discontinuation of LAMICTAL®. Re-exposure resulted in a rapid return of symptoms (from within 30 minutes to 1 day following re-initiation of treatment) that were frequently more severe. Some of the patients treated with LAMICTAL® who ...
ARK™ Oxcarbazepine Metabolite Assay
... Patient sera from patients treated with eslicarbazepine acetate were not evaluated. A range of ratios for the enantiomers (S)-MHD to (R)-MHD was studied by the ARK Oxcarbazepine Metabolite Assay. Individual patient sera from patients treated with oxcarbazepine may contain a metabolite S:R ratio of 4 ...
... Patient sera from patients treated with eslicarbazepine acetate were not evaluated. A range of ratios for the enantiomers (S)-MHD to (R)-MHD was studied by the ARK Oxcarbazepine Metabolite Assay. Individual patient sera from patients treated with oxcarbazepine may contain a metabolite S:R ratio of 4 ...
Labetalol to metoprolol conversion chart
... herein; and these suggested doses and/or guidelines are not a. Medscape - Indicationspecific dosing for Trandate (labetalol), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation. Metoprolol (Lopressor ®) The authors make no claims of the accuracy of ...
... herein; and these suggested doses and/or guidelines are not a. Medscape - Indicationspecific dosing for Trandate (labetalol), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation. Metoprolol (Lopressor ®) The authors make no claims of the accuracy of ...
Guidelines on Similar Biologic: Regulatory Requirements for
... The Similar Biologics are regulated as per the Drugs and Cosmetics Act, 1940, the Drugs and Cosmetics Rules, 1945 (as amended from time to time) and Rules for the manufacture, use, import, export and storage of hazardous microorganisms/ genetically engineered organisms or cells, 1989 (Rules, 1989) n ...
... The Similar Biologics are regulated as per the Drugs and Cosmetics Act, 1940, the Drugs and Cosmetics Rules, 1945 (as amended from time to time) and Rules for the manufacture, use, import, export and storage of hazardous microorganisms/ genetically engineered organisms or cells, 1989 (Rules, 1989) n ...
COMPARATIVE STUDY OF NEUROMUSCULAR
... Objectives: This study evaluates the enhancement of cisatracurium and rocuronium-induced neuromuscular block during anesthesia with 1.5 MAC sevoflurane or total i.v. anesthesia (TIVA), hemodynamic effects and side effects. Methodology: 80 patients were randomly allocated into one of four equal Group ...
... Objectives: This study evaluates the enhancement of cisatracurium and rocuronium-induced neuromuscular block during anesthesia with 1.5 MAC sevoflurane or total i.v. anesthesia (TIVA), hemodynamic effects and side effects. Methodology: 80 patients were randomly allocated into one of four equal Group ...
Opposite effects of MDMA
... 3,4-methylenedioxymethamphetamine (MDMA, “ecstasy”) is widely used by young people for its euphoric effects. MDMA releases serotonin (5-HT), norepinephrine (NE), and dopamine through an interaction with the corresponding presynaptic monoamine uptake transporter. 5HT transport inhibitors block MDMA-i ...
... 3,4-methylenedioxymethamphetamine (MDMA, “ecstasy”) is widely used by young people for its euphoric effects. MDMA releases serotonin (5-HT), norepinephrine (NE), and dopamine through an interaction with the corresponding presynaptic monoamine uptake transporter. 5HT transport inhibitors block MDMA-i ...
ACCUTANE® (isotretinoin) CAPSULES Avoid Pregnancy
... triglycerides, HDL, and cholesterol were reversible upon cessation of Accutane therapy. Some patients have been able to reverse triglyceride elevation by reduction in weight, restriction of dietary fat and alcohol, and reduction in dose while continuing Accutane. Blood lipid determinations should b ...
... triglycerides, HDL, and cholesterol were reversible upon cessation of Accutane therapy. Some patients have been able to reverse triglyceride elevation by reduction in weight, restriction of dietary fat and alcohol, and reduction in dose while continuing Accutane. Blood lipid determinations should b ...
Zeldox oral suspension ENG SmPC
... controlled clinical trials, the combination of ziprasidone plus lithium has not demonstrated an increased clinical risk, compared to lithium alone. There are limited data on co-medication with the mood stabiliser carbamazepine. A pharmacokinetic interaction of ziprasidone with valproate is unlikely ...
... controlled clinical trials, the combination of ziprasidone plus lithium has not demonstrated an increased clinical risk, compared to lithium alone. There are limited data on co-medication with the mood stabiliser carbamazepine. A pharmacokinetic interaction of ziprasidone with valproate is unlikely ...
Antifungals and their use in veterinary ophthalmology - GEAC-UFV
... Pathogenic mechanisms, growth requirements, and antifungal drug susceptibility vary considerably among fungal pathogens [27,28]. Initial treatment of patients with suspected fungal keratitis may be empiric, and choice of therapy is defined by previous clinical experience, available drugs, and financia ...
... Pathogenic mechanisms, growth requirements, and antifungal drug susceptibility vary considerably among fungal pathogens [27,28]. Initial treatment of patients with suspected fungal keratitis may be empiric, and choice of therapy is defined by previous clinical experience, available drugs, and financia ...
Pralidoxime Iodide Injection
... dry mouth and decreased respiratory symptoms will give a good clinical assessment of atropinisation. Children. 20 to 50 mg/kg as intermittent doses required to alleviate symptoms. An infusion can be used after an initial dose has been given. Pralidoxime Iodide Injection 1 g in 5% dextrose and 0.2% s ...
... dry mouth and decreased respiratory symptoms will give a good clinical assessment of atropinisation. Children. 20 to 50 mg/kg as intermittent doses required to alleviate symptoms. An infusion can be used after an initial dose has been given. Pralidoxime Iodide Injection 1 g in 5% dextrose and 0.2% s ...
ANNEX I SUMMARY OF PRODUCT CHARACTERISTICS 1
... riociguat metabolism and excretion (see section 5.2). Concomitant administration of 400 mg once daily ketoconazole led to a 150% (range up to 370%) increase in riociguat mean AUC and a 46% increase in mean Cmax. Terminal half-life increased from 7.3 to 9.2 hours and total body clearance decreased fr ...
... riociguat metabolism and excretion (see section 5.2). Concomitant administration of 400 mg once daily ketoconazole led to a 150% (range up to 370%) increase in riociguat mean AUC and a 46% increase in mean Cmax. Terminal half-life increased from 7.3 to 9.2 hours and total body clearance decreased fr ...
Chapter 11 to 21
... Treatment with cytotoxic drugs should be initiated only after baseline tests of liver and kidney function have been performed and baseline blood counts established. It may be necessary to modify or delay treatment in certain circum-stances. The patient should also be monitored regularly during chemo ...
... Treatment with cytotoxic drugs should be initiated only after baseline tests of liver and kidney function have been performed and baseline blood counts established. It may be necessary to modify or delay treatment in certain circum-stances. The patient should also be monitored regularly during chemo ...
ALBIZIA RATS PROCERA ROXB
... procera significantly reversed the above changes compared to the control group as observed in the paracetamol-challenged rats. Conclusion: The results clearly demonstrate that Albizia procera possesses promising hepatoprotective effects and hence suggests its use as a potential therapeutic agent for ...
... procera significantly reversed the above changes compared to the control group as observed in the paracetamol-challenged rats. Conclusion: The results clearly demonstrate that Albizia procera possesses promising hepatoprotective effects and hence suggests its use as a potential therapeutic agent for ...
Allergic hypersensitivity to topical and systemic corticosteroids
... patients who are allergic to a CS often exhibit co-sensitization to multiple allergens (e.g. preservatives, excipients and antibiotics). Degreef and Dooms-Goossens (18) demonstrated that 82% of their CS-allergic patients were ...
... patients who are allergic to a CS often exhibit co-sensitization to multiple allergens (e.g. preservatives, excipients and antibiotics). Degreef and Dooms-Goossens (18) demonstrated that 82% of their CS-allergic patients were ...
Xenazine® 25 mg
... Tetrabenazine elevates serum prolactin concentrations in humans. Following administration of 25 mg to healthy volunteers, peak plasma prolactin levels increased 4 to 5-fold. Tissue culture experiments indicate that approximately one third of human breast cancers are prolactin-dependent in vitro, a f ...
... Tetrabenazine elevates serum prolactin concentrations in humans. Following administration of 25 mg to healthy volunteers, peak plasma prolactin levels increased 4 to 5-fold. Tissue culture experiments indicate that approximately one third of human breast cancers are prolactin-dependent in vitro, a f ...
Budesonide and formoterol inhibit ICAM-1 and VCAM-1
... role in polymorphonuclear leukocyte transmigration over fibroblasts [24] and T-cell adhesion to fibroblasts in vitro [25]. Eosinophils have been shown at least to adhere to fibroblasts via an ICAM-1-dependent mechanism [26], but are known to express very late activation antigen-4, which adheres to f ...
... role in polymorphonuclear leukocyte transmigration over fibroblasts [24] and T-cell adhesion to fibroblasts in vitro [25]. Eosinophils have been shown at least to adhere to fibroblasts via an ICAM-1-dependent mechanism [26], but are known to express very late activation antigen-4, which adheres to f ...
Zepatier - Merck.com
... hepatitis flare during HCV treatment and post-treatment follow-up. Initiate appropriate patient management for HBV infection as clinically indicated. (5.1) ALT elevations: Perform hepatic laboratory testing prior to therapy, at treatment week 8, and as clinically indicated. For patients receiving ...
... hepatitis flare during HCV treatment and post-treatment follow-up. Initiate appropriate patient management for HBV infection as clinically indicated. (5.1) ALT elevations: Perform hepatic laboratory testing prior to therapy, at treatment week 8, and as clinically indicated. For patients receiving ...
Central Nervous System Side Effects of First- and
... illness within the last 2 weeks; 2) use of antihistamines or any other medications that may affect CNS function in the last 2 weeks; 3) presence of signs or symptoms of asthma or atopic dermatitis; or 4) consumption of dietary items that may contain methylxanthines, such as cola drinks, coffee, or c ...
... illness within the last 2 weeks; 2) use of antihistamines or any other medications that may affect CNS function in the last 2 weeks; 3) presence of signs or symptoms of asthma or atopic dermatitis; or 4) consumption of dietary items that may contain methylxanthines, such as cola drinks, coffee, or c ...
Antidiarrheal activity of methanol leaf extract of Lophira Lanceolata
... This study investigated the effect of methanol leaf extract of Lophira lanceolata for antidiarrheal and spasmolytic properties in experimental albino Wistar rats. The methanol extract (ME) obtained by 72 h maceration was evaluated for antidiarrheal activity using Castor oil induced diarrhea, GIT tra ...
... This study investigated the effect of methanol leaf extract of Lophira lanceolata for antidiarrheal and spasmolytic properties in experimental albino Wistar rats. The methanol extract (ME) obtained by 72 h maceration was evaluated for antidiarrheal activity using Castor oil induced diarrhea, GIT tra ...