Antidiarrheal activity of methanol leaf extract of Lophira Lanceolata
... This study investigated the effect of methanol leaf extract of Lophira lanceolata for antidiarrheal and spasmolytic properties in experimental albino Wistar rats. The methanol extract (ME) obtained by 72 h maceration was evaluated for antidiarrheal activity using Castor oil induced diarrhea, GIT tra ...
... This study investigated the effect of methanol leaf extract of Lophira lanceolata for antidiarrheal and spasmolytic properties in experimental albino Wistar rats. The methanol extract (ME) obtained by 72 h maceration was evaluated for antidiarrheal activity using Castor oil induced diarrhea, GIT tra ...
Clinical Medicine: Therapeutics pharmacotherapy of Fibromyalgia
... the central and peripheral nervous system. Nausea, the most commonly observed side-effect (almost 20%) likewise with selective serotonin reuptake inhibitors, is considered as more directly linked to increased serotonin availability. These side-effects are generally mild or moderate. They appear earl ...
... the central and peripheral nervous system. Nausea, the most commonly observed side-effect (almost 20%) likewise with selective serotonin reuptake inhibitors, is considered as more directly linked to increased serotonin availability. These side-effects are generally mild or moderate. They appear earl ...
14. Narayanan S. et al. Antioxidant activities of Seabuckthorn
... occurs. It is effective in the treatment of cancer (lymphoma, acute and chronic leukemia’s, multiple myeloma) and non-malignant disease states such as rheumatoid arthritis and vasculities. It is inactive until metabolized in the liver by p450 mixed function oxidase. The important side effects are na ...
... occurs. It is effective in the treatment of cancer (lymphoma, acute and chronic leukemia’s, multiple myeloma) and non-malignant disease states such as rheumatoid arthritis and vasculities. It is inactive until metabolized in the liver by p450 mixed function oxidase. The important side effects are na ...
Effects of ciclesonide and fluticasone on cortisol secretion in patients with
... ANCOVA or ANOVA [26] with treatment, period, sequence, patient within sequence and sex as factors. For computation of the ANOVA and ANCOVA analyses the SAS procedure PROC MIXED was utilised, using the baseline value as continuous covariate, the patient within sequence effect as random nested factor ...
... ANCOVA or ANOVA [26] with treatment, period, sequence, patient within sequence and sex as factors. For computation of the ANOVA and ANCOVA analyses the SAS procedure PROC MIXED was utilised, using the baseline value as continuous covariate, the patient within sequence effect as random nested factor ...
Chemical, pharmacokinetic and pharmacodynamic properties of
... pro-drugs, and are enzymatically hydrolysed in vivo to their active, hydroxy-acid form [26]. The other statins are administered as the active hydroxy acid [9,24,27]. Some key pharmacokinetic properties of the individual statins are summarized in Table II. All statins are absorbed rapidly following a ...
... pro-drugs, and are enzymatically hydrolysed in vivo to their active, hydroxy-acid form [26]. The other statins are administered as the active hydroxy acid [9,24,27]. Some key pharmacokinetic properties of the individual statins are summarized in Table II. All statins are absorbed rapidly following a ...
FLUNIXIN - American Academy of Veterinary Pharmacology and
... recommended; in a few animals, one or two additional doses may be necessary if signs of colic return while underlying causes are determined and treated.{R-1} ELUS,CAN For treatment of endotoxemia or sepsis in horses, an intravenous dosage regimen similar to that for colicassociated pain might be use ...
... recommended; in a few animals, one or two additional doses may be necessary if signs of colic return while underlying causes are determined and treated.{R-1} ELUS,CAN For treatment of endotoxemia or sepsis in horses, an intravenous dosage regimen similar to that for colicassociated pain might be use ...
Erectile Dysfunction - UCSF Department of Urology
... cyclic GMP is hydrolyzed to GMP by phosphodiesterase type 5. Other phosphodiesterases are also found in the corpus cavernosum, but they do not appear to have an important role in erection. Communication among smooth-muscle cells takes place through gap junctions in the membranes of adjacent cells, w ...
... cyclic GMP is hydrolyzed to GMP by phosphodiesterase type 5. Other phosphodiesterases are also found in the corpus cavernosum, but they do not appear to have an important role in erection. Communication among smooth-muscle cells takes place through gap junctions in the membranes of adjacent cells, w ...
Journal of Science Chemistry IMPACT OF GIVING SILDENAFIL
... studies have been conducted to study the haemodynamic activity of sildenafil in different animal species (rabbit, dog, rat, cat). These studies have demonstrated that sildenafil has vasodilator properties which can, at higher doses, be associated with reductions in blood pressure and accompanied by ...
... studies have been conducted to study the haemodynamic activity of sildenafil in different animal species (rabbit, dog, rat, cat). These studies have demonstrated that sildenafil has vasodilator properties which can, at higher doses, be associated with reductions in blood pressure and accompanied by ...
The Drug of War
... nursing staff to look after some of the patients, particularly those undergoing burns treatment, without a supervising anaesthetist, who was free to deal with more urgent tasks. This was a very favorable attribute in a military environment. Postoperatively there were very few undesirable affects rep ...
... nursing staff to look after some of the patients, particularly those undergoing burns treatment, without a supervising anaesthetist, who was free to deal with more urgent tasks. This was a very favorable attribute in a military environment. Postoperatively there were very few undesirable affects rep ...
(toceranib phosphate) Tablets
... Your veterinarian has decided to include PALLADIA as a part of your dog’s treatment plan for mast cell tumor. Other types of treatment, such as surgery, drug treatment and/or radiation may be included in the plan. Be sure to speak with your veterinarian about all parts of your dog’s treatment plan ...
... Your veterinarian has decided to include PALLADIA as a part of your dog’s treatment plan for mast cell tumor. Other types of treatment, such as surgery, drug treatment and/or radiation may be included in the plan. Be sure to speak with your veterinarian about all parts of your dog’s treatment plan ...
Virus-Infected Patients )-Methadone in Human Immunodeficiency R
... were also excluded if they were consuming alcohol or using illicit drugs before or during the study period. Patients requiring treatment with medications and herbal substances known to interfere with hepatic drug metabolism were also ineligible. Additionally, patients were told to abstain from drink ...
... were also excluded if they were consuming alcohol or using illicit drugs before or during the study period. Patients requiring treatment with medications and herbal substances known to interfere with hepatic drug metabolism were also ineligible. Additionally, patients were told to abstain from drink ...
Fluticasone Propionate Ointment, 0.005%
... fluticasone propionate ointment 0.005% for atopic dermatitis over at least 35% of body surface area, subnormal adrenal function was observed with cosyntropin stimulation testing at the end of 3 to 4 weeks of treatment in 4 patients who had normal testing prior to treatment. It is not known if these ...
... fluticasone propionate ointment 0.005% for atopic dermatitis over at least 35% of body surface area, subnormal adrenal function was observed with cosyntropin stimulation testing at the end of 3 to 4 weeks of treatment in 4 patients who had normal testing prior to treatment. It is not known if these ...
C 1 G
... Approximate 75% of ADR in patients are classified as Type A ADR which involve lifethreatening exaggerated pharmacological activity (on-target and/or off-target) due to unanticipated increased plasma concentrations of the parent drug. This class of ADR often results from drug-drug interactions or gen ...
... Approximate 75% of ADR in patients are classified as Type A ADR which involve lifethreatening exaggerated pharmacological activity (on-target and/or off-target) due to unanticipated increased plasma concentrations of the parent drug. This class of ADR often results from drug-drug interactions or gen ...
TO THE PHARMACIST
... The recommended dose of LYRICA for fibromyalgia is 300 to 450 mg/day. Begin dosing at 75 mg two times a day (150 mg/day). The dose may be increased to 150 mg two times a day (300 mg/day) within 1 week based on efficacy and tolerability. Patients who do not experience sufficient benefit with 300 mg/d ...
... The recommended dose of LYRICA for fibromyalgia is 300 to 450 mg/day. Begin dosing at 75 mg two times a day (150 mg/day). The dose may be increased to 150 mg two times a day (300 mg/day) within 1 week based on efficacy and tolerability. Patients who do not experience sufficient benefit with 300 mg/d ...
Pr VIAGRA*
... Geriatrics (> 65 years of age): Healthy elderly volunteers had a reduced clearance of sildenafil, with free plasma concentrations approximately 40% greater than those seen in younger volunteers (18 to 45 years). Since higher plasma levels may increase both the pharmacological action and incidence of ...
... Geriatrics (> 65 years of age): Healthy elderly volunteers had a reduced clearance of sildenafil, with free plasma concentrations approximately 40% greater than those seen in younger volunteers (18 to 45 years). Since higher plasma levels may increase both the pharmacological action and incidence of ...
Ulipristal acetate - Therapeutic Goods Administration
... Table 1 (continued): International regulatory status for ulipristal acetate 30 mg tablet. ...
... Table 1 (continued): International regulatory status for ulipristal acetate 30 mg tablet. ...
Martindale: The Complete Drug Reference
... ) has been shown in various studies,1-6 two of which2,5 were ...
... ) has been shown in various studies,1-6 two of which2,5 were ...
Ventolin Prescribing Information
... in patients with asthma. Therefore, patients with asthma should not normally be treated with beta-blockers. However, under certain circumstances, e.g., as prophylaxis after myocardial infarction, there may be no acceptable alternatives to the use of beta-adrenergic blocking agents in patients with a ...
... in patients with asthma. Therefore, patients with asthma should not normally be treated with beta-blockers. However, under certain circumstances, e.g., as prophylaxis after myocardial infarction, there may be no acceptable alternatives to the use of beta-adrenergic blocking agents in patients with a ...
methotrexate
... Since elimination /terminal phase is independent of the dose administered , it reflects the change in distribution & elimination of MTX. Elimination phase is important because the retention of even a very small amount of administered dose can be potentially toxic to the pt. The apparent termin ...
... Since elimination /terminal phase is independent of the dose administered , it reflects the change in distribution & elimination of MTX. Elimination phase is important because the retention of even a very small amount of administered dose can be potentially toxic to the pt. The apparent termin ...
www.chembio.umich.edu
... core of the proteasome includes three proteolytic activities that are commonly described by their substrate selectivities (5): chymotrypsin-like, trypsin-like, and caspase-like. Each proteasome active site uses the side chain hydroxyl group of an NH2-terminal threonine as the catalytic nucleophile, ...
... core of the proteasome includes three proteolytic activities that are commonly described by their substrate selectivities (5): chymotrypsin-like, trypsin-like, and caspase-like. Each proteasome active site uses the side chain hydroxyl group of an NH2-terminal threonine as the catalytic nucleophile, ...
Furosemide - Circulation
... (200 to 800 mg/day). Combination of furosemide with any of the other diuretic agents resulted in natriuretic and diuretic effects which equalled or exceeded the sum of responses observed when the drugs were administered singly. ...
... (200 to 800 mg/day). Combination of furosemide with any of the other diuretic agents resulted in natriuretic and diuretic effects which equalled or exceeded the sum of responses observed when the drugs were administered singly. ...
Methods for assessing the preventability of Linköping University Post Print
... In systematic reviews, the heterogeneity between studies assessing preventable ADEs has been described as a barrier for conducting a meta-analysis on preventable ADEs (4,5). Using different definitions for adverse outcomes and preventability has been suggested to decrease the comparability of differ ...
... In systematic reviews, the heterogeneity between studies assessing preventable ADEs has been described as a barrier for conducting a meta-analysis on preventable ADEs (4,5). Using different definitions for adverse outcomes and preventability has been suggested to decrease the comparability of differ ...
ULTRACET C IV
... of acetaminophen may be intentional to cause self-harm or unintentional as patients attempt to obtain more pain relief or unknowingly take other acetaminophen-containing products (see Boxed Warning). The risk of acute liver failure is higher in individuals with underlying liver disease and in indivi ...
... of acetaminophen may be intentional to cause self-harm or unintentional as patients attempt to obtain more pain relief or unknowingly take other acetaminophen-containing products (see Boxed Warning). The risk of acute liver failure is higher in individuals with underlying liver disease and in indivi ...
New horizons in pulmonary arterial hypertension therapies
... translate into an improved safety profile, particularly with regards to gastrointestinal effects as, unlike iloprost and beraprost, selexipag and its metabolite do not stimulate gastric smooth muscle via the prostaglandin E (EP) receptors EP3 and EP1 [30]. In a phase II proof-of-concept study in 43 ...
... translate into an improved safety profile, particularly with regards to gastrointestinal effects as, unlike iloprost and beraprost, selexipag and its metabolite do not stimulate gastric smooth muscle via the prostaglandin E (EP) receptors EP3 and EP1 [30]. In a phase II proof-of-concept study in 43 ...