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MAXIDOL® Liquid Gels
MAXIDOL® Liquid Gels

... Adults (12-65 years): 1 caplet/capsule every 8 - 12 hours. For individuals over 65 years, 1 capsule every 12 hours. Do not take more than 2 capsules in a 24 hour period. Drink a full glass of water with each dose. Under 12 years: Children under 12 should not take this drug. The safety in pediatric u ...
Eryped 200 (erythromycin ethylsuccinate)  Suspension
Eryped 200 (erythromycin ethylsuccinate) Suspension

... immediate treatment and (2) increase the likelihood that bacteria will develop resistance and will not be treatable by Ery-Ped or other antibacterial drugs in the future. Diarrhea is a common problem caused by antibiotics which usually ends when the antibiotic is discontinued. Sometime after startin ...
selected medicinal plants - E
selected medicinal plants - E

... should be set in accordance with national requirements by the appropriate authorities of Member States. Each medicinal plant and the specific plant part used as crude drug material contains active or major chemical constituents with a characteristic profile that can be used for chemical quality contro ...
Document
Document

... The large number of prescribing problems with oral Methotrexate supported the case to develop a structured electronic prescribing pathway. This was developed by a team comprising the electronic prescribing pharmacists, specialist clinical pharmacists and the rheumatology team. It was decided that, u ...
based Micro and Nanoparticles for the Controlled Drug Delivery of
based Micro and Nanoparticles for the Controlled Drug Delivery of

... potential disadvantages cannot be ignored: possible toxicity or nonbiocompatibility of the materials used, undesirable by-products of degradation, the fact that surgery may be required to implant or remove the system, the possibility of patient discomfort caused by the delivery device, and the highe ...
75/2009 - Repatriation Medical Authority
75/2009 - Repatriation Medical Authority

... "death from adrenal insufficiency" in relation to a person includes death from a terminal event or condition that was contributed to by the person’s adrenal insufficiency; "equivalent glucocorticoid therapy" means a glucocorticoid in the following table, at the doses specified in the table, or a the ...
Aritavi gastro-resistant capsule, hard ENG SmPC
Aritavi gastro-resistant capsule, hard ENG SmPC

... sodium lower than 110 mmol/l. Hyponatraemia may be due to a syndrome of inappropriate anti-diuretic hormone secretion (SIADH). The majority of cases of hyponatraemia were reported in the elderly, especially when coupled with a recent history of, or condition pre-disposing to, altered fluid balance. ...
ARST1431 CHILDREN`S ONCOLOGY GROUP ARST1431 A
ARST1431 CHILDREN`S ONCOLOGY GROUP ARST1431 A

... involuntary release of information about your subjects collected during the course of our covered studies. The researchers involved in the studies cannot be forced to disclose the identity or any information collected in the study in any legal proceedings at the federal, state, or local level, regar ...
A
A

... total of 5 placebo-controlled, double-blind trials have established the efficacy of divalproex in migraine prevention, and other groups have studied its use in cluster and chronic daily headache with mixed results.12-17 A brief review of the evidence is described here but is discussed more extensive ...
Azithromycin for Injection, USP
Azithromycin for Injection, USP

... = 500 mg (2 mg/mL) for 2-5 days in community-acquired pneumonia patients. = 500 mg (1 mg/mL) for 5 days in healthy subjects. The average CLt and Vd values were 10.18 mL/min/kg and 33.3 L/kg, respectively, in 18 normal volunteers receiving 1000 to 4000-mg doses given as 1 mg/mL over 2 hours. Comparis ...
Tinospora crispa – a review
Tinospora crispa – a review

... The efficacy of Tinospora crispa extract for the treatment of diabetes has previously been verified in animal models. The results showed that the antihyperglycaemic effect is not due to interference with intestinal glucose uptake or uptake of the sugar into the peripheral cells and that the antihype ...
Metoprolol iv to oral equivalent
Metoprolol iv to oral equivalent

... succinate (Toprol XL) 25 mg PO qDay initially; increased every 2 weeks PRN; target dosage, 200 mg/day ; New York Heart Association (NYHA) class ≥II. Learn about Toprol XL (Metoprolol Succinate) may treat, uses, dosage, side effects, drug interactions, warnings, patient labeling, reviews, and related ...
Assessment of model BE study
Assessment of model BE study

...  “Phenotyping for metabolizing activity can be of importance for studies with high-clearance drugs that are metabolized by enzymes that are subject to genetic polymorphism, e.g. propranolol. In such cases, slow metabolizers will have a higher bioavailability of the parent drug, while the bioavailab ...
Drugs of abuse modulate dopaminergic neurotransmission : effects
Drugs of abuse modulate dopaminergic neurotransmission : effects

... The term “drugs of abuse” refers to substances that are not taken for medical reasons, but usually for mind-altering effects including feelings of emotional warmth, empathy toward others, enhanced sensory perception, a general sense of well being and decreased anxiety. Many of these drugs are only t ...
- Wiley Online Library
- Wiley Online Library

... derive optimal benefit at concentrations outside the reference range and some will have toxic effects within this range. Concentrations lying within the reference range are not “normal” because the “normal” concentration of a drug in a living organism is zero. Concentrations lying within the referen ...
Synergistic effects of leucine and resveratrol on insulin sensitivity
Synergistic effects of leucine and resveratrol on insulin sensitivity

... metabolism and cellular survival [10,11]. While Sirt3 is located in the mitochondria, Sirt1 is mainly found in the nucleus. Both sense energy status via the NAD+/NADH ratio and modify the acetylation level of histones and proteins such as p53, NF-κB and FOXO [12,13]. Sirt1 and Sirt3 stimulation lead ...
Mecamylamine (a nicotine antagonist) for smoking cessation
Mecamylamine (a nicotine antagonist) for smoking cessation

... 1994; Tennant 1984a; Tennant 1984b). However, at these doses, it produced significant side effects, including drowsiness, postural hypotension and constipation. Rose and colleagues have suggested that co-administration of mecamylamine and nicotine replacement might allow the use of smaller doses of ...
Blood biochemical changes in mice after administration of a mixture
Blood biochemical changes in mice after administration of a mixture

... Currently, from the viewpoint of animal welfare, anesthesia or analgesia is required during experimental procedures in animals that are likely to cause pain. A part of these anesthetics have been reported to influence a blood biochemical level. It is important for us to understand the effect of the ...
Central Nervous System Side Effects of First- and Second
Central Nervous System Side Effects of First- and Second

... illness within the last 2 weeks; 2) use of antihistamines or any other medications that may affect CNS function in the last 2 weeks; 3) presence of signs or symptoms of asthma or atopic dermatitis; or 4) consumption of dietary items that may contain methylxanthines, such as cola drinks, coffee, or c ...
summary of product characteristics
summary of product characteristics

... Evidence from short term studies demonstrate that tumour size is reduced in some patients (prior to surgery) further tumour shrinkage however cannot be expected as a feature of continued long term treatment. Prevention of complications following pancreatic surgery. ...
Imodium Liquid, 2 mg/15 ml Oral Solution PL 15513/0182
Imodium Liquid, 2 mg/15 ml Oral Solution PL 15513/0182

... defined and controlled. The specifications and batch analytical results indicate consistency from batch to batch. There are no outstanding quality issues that would have a negative impact on the benefit/risk balance. NON-CLINICAL No new non-clinical data were submitted and none are required for appl ...
VA Medicaid PDL List (effective 07/01/2011)
VA Medicaid PDL List (effective 07/01/2011)

... o Allergy to medications not requiring service approval o Contraindication to or drug-to-drug interaction with medications not requiring service approval o History of unacceptable/toxic side effects to medications not requiring service approval o Patient’s condition is clinically unstable; changing ...
Accelerating antimalarial drug discovery through repositioning Holly
Accelerating antimalarial drug discovery through repositioning Holly

... 1.7.1 The golden era of drug discovery ................................................................................ 18 1.7.2 Target-based drug discovery ....................................................................................... 19 1.7.2.1 Validated antimalarial drug targets ........ ...
Prescribing Information
Prescribing Information

... usually after extended use. • In the overall management of portal-systemic encephalopathy, it should be recognized that there is serious underlying liver disease with complications such as electrolyte disturbance (e.g., hypokalemia) for which other specific therapy may be required. Hypernatremia has ...
How to Protect Yourself Against Malaria
How to Protect Yourself Against Malaria

... Sunset — the hunt for human blood begins. From dusk to dawn the female Anopheles, the malaria-carrying mosquito searches for a host to supply her with blood. Blood is an absolute necessity for her because it provides the protein needed for the development of her eggs which she later deposits in her ...
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