2001_butterfield_THE SUGARCANE GENOME
... marker order in grasses has been demonstrated over large chromosomal segments (Devos and Gale, 1997), several disease resistance genes are not well conserved and may prove difficult to identify through comparative analysis (Keller and Feuillet, 2000). In polyploids, study of single genes may be comp ...
... marker order in grasses has been demonstrated over large chromosomal segments (Devos and Gale, 1997), several disease resistance genes are not well conserved and may prove difficult to identify through comparative analysis (Keller and Feuillet, 2000). In polyploids, study of single genes may be comp ...
Respiratory Epithelial Gene Expression in Patients with Mild and
... The majority of sex-specific genes was already excluded by the requirement that a probe set be present or marginal in at least 75% of the nasal respiratory epithelium samples to be included in the analysis. Probe sets identified as significantly differentially expressed by disease phenotype underwent a ...
... The majority of sex-specific genes was already excluded by the requirement that a probe set be present or marginal in at least 75% of the nasal respiratory epithelium samples to be included in the analysis. Probe sets identified as significantly differentially expressed by disease phenotype underwent a ...
Genomic data mining
... Functions available allow extraction of identifiers from different sources including Ensembl IDs, several microarray platforms, UniProt, RefSeq [21], and EntrezGene [22]. Genome sequences can be retrieved by specific chromosomal coordinates for a given species, allowing a user to mine regions they d ...
... Functions available allow extraction of identifiers from different sources including Ensembl IDs, several microarray platforms, UniProt, RefSeq [21], and EntrezGene [22]. Genome sequences can be retrieved by specific chromosomal coordinates for a given species, allowing a user to mine regions they d ...
Microcin B17 Blocks DNA Replication and Induces
... the colicins, is non-lethal for the producing cell, and is not stimulated by agents which induce the SOS response (Baquero & Moreno, 1984). In most cases microcin production is plasmiddependent and, hitherto, five types of microcins have been identified by cross-immunity, biochemical and genetic cri ...
... the colicins, is non-lethal for the producing cell, and is not stimulated by agents which induce the SOS response (Baquero & Moreno, 1984). In most cases microcin production is plasmiddependent and, hitherto, five types of microcins have been identified by cross-immunity, biochemical and genetic cri ...
Tandem and segmental gene duplication and
... of the NBS, or the LRR region, or consist only of a TIRdomain. In grass species, TIR-NBS-LRR genes have not yet been identified, but the CC-type is very common [5]. In different plants, NBS-LRR loci are found both as isolated genes (singletons) and as tightly linked arrays of related genes (gene clu ...
... of the NBS, or the LRR region, or consist only of a TIRdomain. In grass species, TIR-NBS-LRR genes have not yet been identified, but the CC-type is very common [5]. In different plants, NBS-LRR loci are found both as isolated genes (singletons) and as tightly linked arrays of related genes (gene clu ...
Genetic and Epigenetic Aspects of Polyploid Evolution in Plants
... originating from the different species making up the allopolyploid genome [Stebbins, 1947]. In addition to these 2 canonical forms of polyploidy, a continuum of cytotypic states is possible during meiosis. For example, there may be majority disomic homologous pairing in species where the homoeologou ...
... originating from the different species making up the allopolyploid genome [Stebbins, 1947]. In addition to these 2 canonical forms of polyploidy, a continuum of cytotypic states is possible during meiosis. For example, there may be majority disomic homologous pairing in species where the homoeologou ...
Microarrays - Consortium for Mathematics and its Applications
... parts being red, some tan and some black. You tell Ralph that you are concerned that this mole may have developed into melanoma, a type of skin cancer, and that he should see a specialist as soon as possible. Your nurse calls a dermatologist that specializes in melanomas and sets up an appointment f ...
... parts being red, some tan and some black. You tell Ralph that you are concerned that this mole may have developed into melanoma, a type of skin cancer, and that he should see a specialist as soon as possible. Your nurse calls a dermatologist that specializes in melanomas and sets up an appointment f ...
Ch 15 summary - OHS General Biology
... X inactivation involves modification of the DNA and the histone proteins bound to it by attachment of methyl (—CH3) groups to one of the nitrogenous bases of DNA nucleotides. ...
... X inactivation involves modification of the DNA and the histone proteins bound to it by attachment of methyl (—CH3) groups to one of the nitrogenous bases of DNA nucleotides. ...
Chapter 15 Notes
... X inactivation involves modification of the DNA and the histone proteins bound to it by attachment of methyl (—CH3) groups to one of the nitrogenous bases of DNA nucleotides. ...
... X inactivation involves modification of the DNA and the histone proteins bound to it by attachment of methyl (—CH3) groups to one of the nitrogenous bases of DNA nucleotides. ...
Chapter 15 Outline- The Chromosomal Basis of Inheritance
... X inactivation involves modification of the DNA and the histone proteins bound to it by attachment of methyl (—CH3) groups to one of the nitrogenous bases of DNA nucleotides. ...
... X inactivation involves modification of the DNA and the histone proteins bound to it by attachment of methyl (—CH3) groups to one of the nitrogenous bases of DNA nucleotides. ...
CHARACTERlZATION OF THE ~ 0 CHONDRIA . L DNA MOLECULE
... tRNApro and tRNAphe and varies considerably in size (879 bp in mouse; 1122 bp in human and 2134 bp in h g , Xenopus Inevis)(WoIstenholme, 1992). In marnmds and amphibia, thk sequence has been shown to include the signais necessary for both the initiation of transcription and replication (Montoya et ...
... tRNApro and tRNAphe and varies considerably in size (879 bp in mouse; 1122 bp in human and 2134 bp in h g , Xenopus Inevis)(WoIstenholme, 1992). In marnmds and amphibia, thk sequence has been shown to include the signais necessary for both the initiation of transcription and replication (Montoya et ...
How is the biological information arranged in genome?
... regions that were expressed, replicated, transcribed and translated into proteins, and all participate in biological phenomena. Individual gene, i.e., a protein to be converted throughout the gene, was a part of genome (Figure 1). Each gene could be converted to respective protein according to the m ...
... regions that were expressed, replicated, transcribed and translated into proteins, and all participate in biological phenomena. Individual gene, i.e., a protein to be converted throughout the gene, was a part of genome (Figure 1). Each gene could be converted to respective protein according to the m ...
BMC Genomics
... tes present a bidirectional replication starting from the origin of replication and reading in both directions until reaching a terminus (replication inset). The bidirectional replication therefore defines a leading and a lagging strand in the double helix. In the contrary, nucleotide sequence readi ...
... tes present a bidirectional replication starting from the origin of replication and reading in both directions until reaching a terminus (replication inset). The bidirectional replication therefore defines a leading and a lagging strand in the double helix. In the contrary, nucleotide sequence readi ...
TTEST – Between subjects
... the distribution of the test statistic. • The ability to dynamically alter the input parameters based on immediate visual feedback, even before completing the analysis, should make the data-mining ...
... the distribution of the test statistic. • The ability to dynamically alter the input parameters based on immediate visual feedback, even before completing the analysis, should make the data-mining ...
Sex Linked Inheritance, Chromosome Mapping
... • The closer together two genes are, the more likely they will be inherited together. • Cross-over frequencies are related to distances between genes. • Linkage maps show the relative locations of genes. ...
... • The closer together two genes are, the more likely they will be inherited together. • Cross-over frequencies are related to distances between genes. • Linkage maps show the relative locations of genes. ...
The Macaque Genome: Lessons from Comparative
... similarities and differences among organisms. However, the instructions for specifying many of those characteristics are derived from a given organism's DNA, or genome. That means that the finer details about the relatedness among organisms and the traits that make them similar or different, can oft ...
... similarities and differences among organisms. However, the instructions for specifying many of those characteristics are derived from a given organism's DNA, or genome. That means that the finer details about the relatedness among organisms and the traits that make them similar or different, can oft ...
Complete Mitochondrial DNA Sequences of Six
... 2002; Vidal and Hedges 2002; Wilcox et al. 2002; Vidal and David 2004). These previous studies based on a few mitochondrial or nuclear genes, as well as immunological data partly confirmed the morphological view on snake phylogeny, but disagreed with it or with each other in several respects. There s ...
... 2002; Vidal and Hedges 2002; Wilcox et al. 2002; Vidal and David 2004). These previous studies based on a few mitochondrial or nuclear genes, as well as immunological data partly confirmed the morphological view on snake phylogeny, but disagreed with it or with each other in several respects. There s ...
Uncovering evolutionary patterns of gene expression using
... Figure I. Experimental principles of a two-color experiment using cDNA microarrays. (a) The level of expression of ideally the whole gene complement of a particular organism in two samples of interest is to be estimated. To this end, the two samples under study, which can comprise either total RNA o ...
... Figure I. Experimental principles of a two-color experiment using cDNA microarrays. (a) The level of expression of ideally the whole gene complement of a particular organism in two samples of interest is to be estimated. To this end, the two samples under study, which can comprise either total RNA o ...
Identification of genes that regulate the left
... experiments with cosmid clones in the region showed that hu176 could be rescued by T28F12 and H06N16, indicating that the gene mutated in hu176 is within the region of overlap between these two cosmid clones. A gene in this region, T28F12.2, is the previously identified locus unc-62, which encodes a ...
... experiments with cosmid clones in the region showed that hu176 could be rescued by T28F12 and H06N16, indicating that the gene mutated in hu176 is within the region of overlap between these two cosmid clones. A gene in this region, T28F12.2, is the previously identified locus unc-62, which encodes a ...
The Functions of Introns: From Junk DNA to Designed DNA
... [GT at the start or donor (3’) end and AG at the other end, called the acceptor (5’) site] which help to identify introns for removal. The term “consensus sequence” is employed because, although the sites may consist of more than just GT donor and AG acceptor bases, so far as is known these sequence ...
... [GT at the start or donor (3’) end and AG at the other end, called the acceptor (5’) site] which help to identify introns for removal. The term “consensus sequence” is employed because, although the sites may consist of more than just GT donor and AG acceptor bases, so far as is known these sequence ...
B1 SHA - you and your genes
... True of False • Chromosomes are found in the nucleus. • Sperm and egg cells have the same amount of information as other body cells. • When we are adults our cells stop dividing. • Everyone in this room in unique. • Genes are joined up into chains called chromosomes. • The environment we grow up in ...
... True of False • Chromosomes are found in the nucleus. • Sperm and egg cells have the same amount of information as other body cells. • When we are adults our cells stop dividing. • Everyone in this room in unique. • Genes are joined up into chains called chromosomes. • The environment we grow up in ...
Chromosome structure and mutations
... Mosaics – aneuploid and normal tissues that lie side-by-side ...
... Mosaics – aneuploid and normal tissues that lie side-by-side ...
Storage cells in the bone marrow
... What should we do? • We should follow the WHO classification but should note the presence of relevant cytogenetic abnormalities • We should recognize that topoisomerase IIinhibitor-related secondary AML is quite a different matter from t-AML related to alkylating ...
... What should we do? • We should follow the WHO classification but should note the presence of relevant cytogenetic abnormalities • We should recognize that topoisomerase IIinhibitor-related secondary AML is quite a different matter from t-AML related to alkylating ...
Oncogenomics
Oncogenomics is a relatively new sub-field of genomics that applies high throughput technologies to characterize genes associated with cancer. Oncogenomics is synonymous with ""cancer genomics"". Cancer is a genetic disease caused by accumulation of mutations to DNA leading to unrestrained cell proliferation and neoplasm formation. The goal of oncogenomics is to identify new oncogenes or tumor suppressor genes that may provide new insights into cancer diagnosis, predicting clinical outcome of cancers, and new targets for cancer therapies. The success of targeted cancer therapies such as Gleevec, Herceptin, and Avastin raised the hope for oncogenomics to elucidate new targets for cancer treatment.Besides understanding the underlying genetic mechanisms that initiates or drives cancer progression, one of the main goals of oncogenomics is to allow for the development of personalized cancer treatment. Cancer develops due to an accumulation of mutations in DNA. These mutations accumulate randomly, and thus, different DNA mutations and mutation combinations exist between different individuals with the same type of cancer. Thus, identifying and targeting specific mutations which have occurred in an individual patient may lead to increased efficacy of cancer therapy.The completion of the Human Genome Project has greatly facilitated the field of oncogenomics and has increased the abilities of researchers to find cancer causing genes. In addition, the sequencing technologies now available for sequence generation and data analysis have been applied to the study of oncogenomics. With the amount of research conducted on cancer genomes and the accumulation of databases documenting the mutational changes, it has been predicted that the most important cancer-causing mutations, rearrangements, and altered expression levels will be cataloged and well characterized within the next decade.Cancer research may look either on the genomic level at DNA mutations, the epigenetic level at methylation or histone modification changes, the transcription level at altered levels of gene expression, or the protein level at altered levels of protein abundance and function in cancer cells. Oncogenomics focuses on the genomic, epigenomic, and transcript level alterations in cancer.