• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Recombinant Baculovirus:
Recombinant Baculovirus:

Biology Final Study Guide
Biology Final Study Guide

... 14. What are the three types of symbiotic relationships and give an example of each? 15. Draw logistic and exponential growth models. 16. Compare & contrast chloroplast & mitochondria (job, what cell types have it, equation) 17. What are the main steps in the water, carbon, and nitrogen cycle? Unit ...
Oncology Program 2013 Annual Report
Oncology Program 2013 Annual Report

... colonoscopy. He encouraged the community to follow NCCN guidelines for colon cancer screening by having a colonoscopy at age 50 and one every 10 years after that. In October of 2013, the Cancer Program in conjunction with the Radiology department had a booth in the main lobby of the hospital for bre ...
Genetic Organization and Control
Genetic Organization and Control

... and by whom? 7. Is this draft without error? ...
Fight against cancer: EU research develops cancer   killing isotopes
Fight against cancer: EU research develops cancer killing isotopes

Targeting Advanced Prostate Cancer
Targeting Advanced Prostate Cancer

... The second group, called stromal targeting agents, predominantly targets the bone microenvironment. So far, single-agent trials have demonstrated the proof of principle that candidate stromaltargeting drugs can modulate the tumor microenvironment. One example, still in clinical trials, is atrasentan ...
Macroevolution
Macroevolution

... Developmental Mechanisms Chapter 24 ...
Decode the following message.
Decode the following message.

... removed from a DNA sequence at single point. • An deletion of one base pair causes a shift in the reading frame = One or more amino acids changed Base Pair Removed ...
TEKS 5C – describe the roles of DNA, ribonucleic acid (RNA), and
TEKS 5C – describe the roles of DNA, ribonucleic acid (RNA), and

... results in the production of more pigment by the skin cells (tanning). This change in skin color provides evidence that A the inheritance of skin color is an acquired characteristic. B albinism is a recessive characteristic. C ultraviolet light can cause mutations. D the environment can influence ge ...
What Every Jewish Family Should Know About Breast and Ovarian
What Every Jewish Family Should Know About Breast and Ovarian

... mutation, there are options available for lowering your cancer risk and for detecting cancer at an earlier, more treatable stage. If you test negative for a BRCA mutation, your risk for breast and ovarian cancer will vary depending on other factors. An expert in cancer genetics can best clarify the ...
Dear Family Member: This letter is to notify you that our family has
Dear Family Member: This letter is to notify you that our family has

... is a genetic (inherited) condition that is associated with an increased susceptibility to multiple types of cancer. The purpose of this letter is to familiarize you with hereditary cancer risk, and the steps that you can take to reduce the risk of cancer. Lynch syndrome is associated with an increas ...
Understanding Genetic Cancer Risk: BRCA1 and 2
Understanding Genetic Cancer Risk: BRCA1 and 2

... test looks in the BRCA1 and BRCA2 genes for any changes that are linked to cancer risk. If possible, the person who has had cancer should be tested before other family members. This helps us see whether or not a gene is linked with the cancer in the family. ...
lec#24
lec#24

... leading to cancer • DNA repair genes are recessive, but some act in a haploinsufficiency fashion • A cell with DNA repair gene mutated is not neoplastic yet but has the capacity to accumulate carcinogenic mutations. At this stage it is a “mutator phenotype” ...
Project Title: Characterization of new genes mediating exchange of
Project Title: Characterization of new genes mediating exchange of

... This nuclease creates a break in yeast chromosome III at a single site that cannot be repaired if cells are defective in intrachromosomal DNA recombination. She identified 10 previously unrecognized genes that cause cells to become hypersensitive to HO endonuclease expression. Two of these genes als ...
5th and 6th grade Ch 4 test Notes:
5th and 6th grade Ch 4 test Notes:

... B) Recessive needs two genes to dominant C) You need to read a Punnett Square D) One Dominant and one recessive gene equals a hybrid trait. Part B Short Answer 1. Answer questions based on a chart of Body Cell Chromosomes number. Remember that sex cells have ½ of the number of body cells. 2 Why are ...
PrognoScan slides
PrognoScan slides

... AML; Munich OS (218163_at) ...
14-3 Human Molecular Genetics
14-3 Human Molecular Genetics

... is replaced by a normal, working gene. - This way the body can make the correct protein or enzyme it needs, which eliminates the cause of the disorder. ...
PDF
PDF

... and have abnormal centrosomes (1, 2). In addition, there is as yet no functional proof that the mutations cause aneuploidy. I therefore suggest that both the abnormal structures and numbers of centrosomes in cancer cells are caused by aneuploidy (9-11). Because aneuploidy unbalances huge numbers of ...
compgenomics
compgenomics

Slide 1
Slide 1

... expression by codons this can change the reading resulting in a completely different translation from the original. ...
TRUE FALSE 1. It is important to make the right choice between
TRUE FALSE 1. It is important to make the right choice between

PCR - University of Hawaii
PCR - University of Hawaii

... • mutations are changes to the base pair sequence of genetic material (either DNA or RNA). Mutations can be caused by copying errors in the genetic material during cell division and by exposure to ultraviolet or ionizing radiation, chemical mutagens, or viruses ...
CHAPTER 14: Genes in Action Essential Ideas
CHAPTER 14: Genes in Action Essential Ideas

... DOWNS SYNDROME =TRISOMY21 (3 copies of a chromosome 21) mental delays, changes in blood vessels and connective tissue ...
BRCA1 - BioSyL
BRCA1 - BioSyL

Gene Section OSGIN1 (oxidative stress induced growth inhibitor 1)
Gene Section OSGIN1 (oxidative stress induced growth inhibitor 1)

... Breast cancer is the most common cancer and the second top cause of cancer death among women. The American Cancer Society's estimates about 232670 new cases of invasive breast cancer will be diagnosed in women in the US for 2014. Risk factors associated with breast cancer include age, geography, fam ...
< 1 ... 468 469 470 471 472 473 474 475 476 ... 504 >

Oncogenomics



Oncogenomics is a relatively new sub-field of genomics that applies high throughput technologies to characterize genes associated with cancer. Oncogenomics is synonymous with ""cancer genomics"". Cancer is a genetic disease caused by accumulation of mutations to DNA leading to unrestrained cell proliferation and neoplasm formation. The goal of oncogenomics is to identify new oncogenes or tumor suppressor genes that may provide new insights into cancer diagnosis, predicting clinical outcome of cancers, and new targets for cancer therapies. The success of targeted cancer therapies such as Gleevec, Herceptin, and Avastin raised the hope for oncogenomics to elucidate new targets for cancer treatment.Besides understanding the underlying genetic mechanisms that initiates or drives cancer progression, one of the main goals of oncogenomics is to allow for the development of personalized cancer treatment. Cancer develops due to an accumulation of mutations in DNA. These mutations accumulate randomly, and thus, different DNA mutations and mutation combinations exist between different individuals with the same type of cancer. Thus, identifying and targeting specific mutations which have occurred in an individual patient may lead to increased efficacy of cancer therapy.The completion of the Human Genome Project has greatly facilitated the field of oncogenomics and has increased the abilities of researchers to find cancer causing genes. In addition, the sequencing technologies now available for sequence generation and data analysis have been applied to the study of oncogenomics. With the amount of research conducted on cancer genomes and the accumulation of databases documenting the mutational changes, it has been predicted that the most important cancer-causing mutations, rearrangements, and altered expression levels will be cataloged and well characterized within the next decade.Cancer research may look either on the genomic level at DNA mutations, the epigenetic level at methylation or histone modification changes, the transcription level at altered levels of gene expression, or the protein level at altered levels of protein abundance and function in cancer cells. Oncogenomics focuses on the genomic, epigenomic, and transcript level alterations in cancer.
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report