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PRESCRIBING INFORMATION Entex LA Pseudoephedrine
PRESCRIBING INFORMATION Entex LA Pseudoephedrine

... ingested is considered dangerous or excessive, induce vomiting with ipecac syrup unless the patient is convulsing, comatose, or has lost the gag reflex, in which case perform gastric lavage using a large bore tube. If indicated, follow with activated charcoal and saline cathartic. Since the effects ...
Practical Guidelines for Clinicians Who Treat Patients With
Practical Guidelines for Clinicians Who Treat Patients With

... amiodarone therapy in preventing sudden cardiac death. Moreover, the AVID trial6 showed improvement in overall survival. Of patients who have ICDs, 30% to 70% require concomitant antiarrhythmic treatment. Amiodarone is effective in slowing the rate of VT, as tested in the electrophysiology laborator ...
Bulletin #106
Bulletin #106

... wet nebulized drugs because more effective and less expensive drugpowdered forms of the same medications are available.” The Saskatchewan drug review committees support these findings and following a discussion of the literature, a review of initiatives in other provinces and a review of utilization ...
a homeopathic remedy for cardiac ailment
a homeopathic remedy for cardiac ailment

... contraction. But it is yet to be confirmed, by clinical data analysis. Initial research involving the commercial preparations of active compound reported it to be physiologically inert. However, in recent studies, hordenine showed a positive inotropic effect in the myocardium of rats and dogs with i ...


... of the vasoconstrictor partially purified by the method of Rapport et al. (1948a). All these actions appeared to be due to a single substance, a conclusion which was further supported by the fact that they were mimicked by those of one group of compounds-the indolalkylamines. So far as the vascular ...
Stimulants - Australian Indigenous HealthInfoNet
Stimulants - Australian Indigenous HealthInfoNet

... • ‘Amphetamine’ powder (speed): is usually white or yellow in colour and is usually not very pure (around 5% methamphetamine). It is the most common form of methamphetamine in Australia, and is usually snorted but can also be swallowed or injected. • Crystalline methamphetamine (ice, crystal, crys ...
The Pedunculopontine Tegmental Nucleus as a Motor and
The Pedunculopontine Tegmental Nucleus as a Motor and

... non-cholinergic neurons such as glutamatergic and GABAergic neurons (Jones and Beaudet, 1987; Clements and Grant, 1990; Spann and Grofova, 1992; Ford et al., 1995; Wang and Morales, 2009). A more recent report suggests that there is a different intrinsic connectivity in the rostral vs. caudal aspect ...
Primer for Investigational New Drug
Primer for Investigational New Drug

... Scenario 1: Yes. An IND is needed for this study because: a) it involves the use of a product for the purpose of mitigating the effects of a disease, and b) the results may be used in support of a new indication for labeling and/or marketing. Scenario 2: Yes. An IND is needed for this study because: ...
Performance enhancing drugs
Performance enhancing drugs

... Performance enhancement: medical models The foundation of modern pharmacy is medical innovation and drug development within a disease-based model. Several factors contribute to the increased use of drugs as enhancers ...
Bigger brains cycle faster before neurogenesis begins: a
Bigger brains cycle faster before neurogenesis begins: a

... and cell cycle rates in the brains of embryonic chickens and bobwhite quail. We report that most aspects of brain maturation occur at similar times in these two species, if time is expressed as percentage of incubation. Therefore, species differences in neurogenesis timing cannot account for the dif ...
Research Protocol - Newcastle University
Research Protocol - Newcastle University

... (from 6 to 18) and paramethoxyamphetamine (PMA) or paramethoxymethamphetamine (PMMA, from 1 to 20) between 2011 and 2012.27 There is a lack of available information on indicators of morbidity, such as numbers of hospital attendances or admissions after use of NPS, although enquiries from health prof ...
EFFECTS OF COFFEE ON THE CENTRAL NERVOUS SYSTEM
EFFECTS OF COFFEE ON THE CENTRAL NERVOUS SYSTEM

... psychostimulant effects of caffeine than usual consumers (Uhde, 1990). The level of anxiety is also more markedly increased in naturally anxious individuals or subjects suffering from panic attacks compared to the normal population. These individuals show the tendency to reduce or stop their caffein ...
Document
Document

... The lipid-modifying effects of fibrates are largely mediated by their ability to activate peroxisome proliferator-activated receptors (PPARs). PPARa controls a number of genes involved in lipid metabolism, including those encoding for apo-CIII, apo-AI, and apo-AII. Fibrates reduce triglycerides thro ...
DEVELOPMENT AND VALIDATION OF A RP-HPLC METHOD FOR THE DETECTION... MEROPENEM AS A PURE COMPOUND, IN A PHARMACEUTICAL DOSAGE FORM...
DEVELOPMENT AND VALIDATION OF A RP-HPLC METHOD FOR THE DETECTION... MEROPENEM AS A PURE COMPOUND, IN A PHARMACEUTICAL DOSAGE FORM...

... chemically termed as (4R,5S,6S)-3-[[(3S,5S)-5-dimethylcarbamoylpyrrolidin-3-yl]-thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo1-azabicyclo[3,2,0]hept-2-ene-2-carboxylic acid [2] and its structure is shown in Figure 1. The antibacterial activity of Meropenem is associated with its high affinity for a v ...
Chapter 32 Airway Pharmacology
Chapter 32 Airway Pharmacology

... combined anticholinergic & -agonist • Ipratropium bromide & albuterol (Combivent, Duoneb) is indicated for patients with COPD or asthma ...
Design and Characterization of Fast Dissolving Films of Valsartan
Design and Characterization of Fast Dissolving Films of Valsartan

... As all the formulations contain different amount of polymers, the thickness was gradually increased with the amount of polymers. All the film formulations were found to have thickness in the range of 0.198 to 0.205 mm and were observed within the limits. The compositional variation of selected polym ...
Cabergonicht 2 mg tablet ENG SmPC
Cabergonicht 2 mg tablet ENG SmPC

... Cabergoline is a synthetic ergot alkaloid and an ergoline derivate with long-acting dopamine agonist and prolactin-inhibiting properties. A central dopaminergic effect via D2receptor stimulation is achieved through higher doses than doses that reduce the levels of serum prolactin. Controlled clinic ...
Review. Current advances on ABC drug transporters in fish
Review. Current advances on ABC drug transporters in fish

... 5.2 Regulation of ABC transporters as part of a general cellular stress response 5.3 Roles of nuclear receptors in ABC transporter regulation 5.4 Hormonal effects on ABC transporters 5.5 Chemical effects on ABC transporter expression in fish 5.6 Altered ABC transporter expression in fish from pollut ...
A Systematic Review on Advanced Drug Delivery Technologies to
A Systematic Review on Advanced Drug Delivery Technologies to

DACOGEN decitabine for injection QUALITATIVE AND
DACOGEN decitabine for injection QUALITATIVE AND

... There is no accumulation of decitabine in plasma when given every eight hours for three consecutive days. The pharmacokinetics reported after administration of DACOGEN daily as a 1hour infusion for 5 consecutive days in 23 patients produced similar results. Distribution: The steady-state volume of d ...
except subgroup TG > 200 mg/dL and HDL-C
except subgroup TG > 200 mg/dL and HDL-C

... > However the primary end point occurred in 282 patients in the niacin group (16.4%) and in 274 patients in the placebo group (16.2%) (hazard ratio, 1.02, P=0.79 by the log-rank test). ...
SERIES ‘‘PULMONARY HYPERTENSION: BASIC CONCEPTS FOR PRACTICAL MANAGEMENT’’
SERIES ‘‘PULMONARY HYPERTENSION: BASIC CONCEPTS FOR PRACTICAL MANAGEMENT’’

... support the existence of cross-regulation or cross-talk between ETRs in various cells types [14–16]. As is the case for many other GPCRs, there is also evidence that the ETAR and ETBR can form functional heterodimers and that this may be of some pharmacological importance [15, 17–19]. Finally, numer ...
Prescribing Information - PI
Prescribing Information - PI

... antithrombotic therapy, smoking cessation, exercise, and limited sodium intake. Many patients will require more than one drug to achieve blood pressure goals. For specific advice on goals and management, see published guidelines, such as those of the National High Blood Pressure Education Program’s ...
The use of compound topical anesthetics
The use of compound topical anesthetics

... pharmacy practice since its origins. Before synthetic and premade pharmaceuticals were available, physicians would write prescriptions that local pharmacists would compound to produce capsules, tablets or suspensions. Industrial drug manufacturing, however, was able to produce drugs more efficiently ...
Redalyc.An analysis of the anxiolytic effects of ethanol on
Redalyc.An analysis of the anxiolytic effects of ethanol on

... training trials, either 32% or 4% sucrose solution. A day before the start of training, rats were exposed to the sucrose solution during 30 min in their home cages. Each rat received exposure to the concentration that corresponded to the training trials (either 32% or 4% sucrose). This pretraining e ...
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Neuropharmacology

Neuropharmacology is the study of how drugs affect cellular function in the nervous system, and the neural mechanisms through which they influence behavior. There are two main branches of neuropharmacology: behavioral and molecular. Behavioral neuropharmacology focuses on the study of how drugs affect human behavior (neuropsychopharmacology), including the study of how drug dependence and addiction affect the human brain. Molecular neuropharmacology involves the study of neurons and their neurochemical interactions, with the overall goal of developing drugs that have beneficial effects on neurological function. Both of these fields are closely connected, since both are concerned with the interactions of neurotransmitters, neuropeptides, neurohormones, neuromodulators, enzymes, second messengers, co-transporters, ion channels, and receptor proteins in the central and peripheral nervous systems. Studying these interactions, researchers are developing drugs to treat many different neurological disorders, including pain, neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease, psychological disorders, addiction, and many others.
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