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IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)

... One of the greatest services a doctor can do to his patients is to acquire skill in the management of pain. Pain is experienced as having qualities such as sharp, throbbing, dull, nauseating, burning and shooting. Pain receptors are free nerve endings. There are mechanical, thermal and chemical pain ...
Cephalexin Product Information Australia DRAFT
Cephalexin Product Information Australia DRAFT

... Dilution or diffusion techniques – either quantitative (MIC) or breakpoint, should be used following a regularly updated, recognised and standardised method (e.g. NCCLS). Standardised susceptibility test procedures require the use of laboratory control microorganisms to control the technical aspects ...
Basics Pharmacology Review - Dr. Roland Halil
Basics Pharmacology Review - Dr. Roland Halil

... Pharmacist, Bruyere Academic FHT Assistant Professor, Dept Family Medicine, U of Ottawa March 2015 ...
Epilepsy - med.muni
Epilepsy - med.muni

... Basic rules for drug treatment: Drug treatment should be simple, preferably using one anticonvulsant (monotherapy). “Start low, increase slow“. Add-on therapy is necessary in some patients… ...
Cannabis - Alberta Health Services
Cannabis - Alberta Health Services

... tobacco.  Heavy marijuana users have lung damage similar to the kind that precedes lung cancer in  tobacco smokers. There are also reports suggesting that people who smoke both marijuana and tobacco  may develop lung, neck and head cancers at an earlier age than those who smoke only tobacco.   Heavy ...
Bioinformatics (2011) 27
Bioinformatics (2011) 27

... In ligand-based methods such as quantitative structure-activity relationships (QSAR) and support vector machine (SVM), the potential ligand binding is predicted based on similarity with the known ligand structure and its physicochemical properties. A number of studies have been published that use in ...
DYRENIUM® (triamterene USP) Capsules 50 mg and 100 mg
DYRENIUM® (triamterene USP) Capsules 50 mg and 100 mg

... Teratogenic Effects: Reproduction studies have been performed in rats at doses as high as 20 times the Maximum Recommended Human Dose (MRHD) on the basis of body weight, and 6 times the MRHD on the basis of body-surface area, without evidence of harm to the fetus due to triamterene. Because animal r ...
Journal of Legal Medicine The Need for Ibogaine in
Journal of Legal Medicine The Need for Ibogaine in

... Downloaded By: [New York University] At: 17:30 11 March 2011 ...
Prescribing Information
Prescribing Information

... The recommended oral dose of INTELENCE® tablets is 200 mg (one 200 mg tablet or two 100 mg tablets) taken twice daily following a meal [see Clinical Pharmacology (12.3)]. The type of food does not affect the exposure to etravirine. 2.2 Pediatric Patients (6 years to less than 18 years of age) The r ...
Chapter 7 - emseducation.info
Chapter 7 - emseducation.info

... • Medications may alleviate pain and improve patient’s well-being. • Used inappropriately, may cause harm and even death. ...
antihistamines in allergic disease
antihistamines in allergic disease

... onset of effect occurs within 1-3 hours; their duration of action varies from several hours to 24 hours, (second-generation drugs being generally around 24 hours) (Table II).7 First-generation antihistamines and some of the second-generation agents are oxidatively metabolised by the hepatic cytochro ...
Chapter_07
Chapter_07

... • Medications may alleviate pain and improve patient’s well-being. • Used inappropriately, may cause harm and even death. ...
ARCI-025-020 Medications and Prohibited Substances
ARCI-025-020 Medications and Prohibited Substances

... (g) Local anesthetics which that have a reasonable potential for use as nerve blocking agents (except procaine); and (h) Snake venoms and other biologic substances, which may be used as nerve blocking agents. (3) Class 3 Drugs placed in this class may or may not have an accepted therapeutic use in t ...
CHALLENGES AND KEY CONSIDERATIONS FOR THE
CHALLENGES AND KEY CONSIDERATIONS FOR THE

... this market and standards have been developed and unified over the last 30 years, which clearly outline how conformance to medical device sterilisation standards can be undertaken. The latest version of ISO 11137: 2006, “Sterilisation of health care products – Radiation – Part 1: Requirements for de ...
ECG Manifestations: The Poisoned Patient
ECG Manifestations: The Poisoned Patient

... also influence the QT interval, such as the patient’s sex and electrolyte concentrations. In addition to QT interval prolongation, there is also the potential emergence of T- or U-wave abnormalities on the ECG with this class of medications [10]. Moreover, delay of repolarization causes the myocardia ...
MIFLONIDE
MIFLONIDE

... symptoms). The patient should be reassessed and the need for increased anti-inflammatory therapy, an increase in the dose of inhaled or oral corticosteroid, should be considered. Paradoxical bronchospasm In rare cases inhalation can cause bronchospasm after dosing. If paradoxical bronchospasm occurs ...
Moxy® drug-coated balloon: a novel device for the treatment of
Moxy® drug-coated balloon: a novel device for the treatment of

... hydrophilic carrier that is designed to minimise the loss of drug during transit and to optimise the drug uptake by target vessel tissue during angioplasty. Paclitaxel is evenly distributed along the working length of the balloon at a surface concentration of 2 µg/mm2 (33% lower than other DCBs).The ...
(4)CCF DRUGS
(4)CCF DRUGS

... norepinephrine; AII, angiotensin II; ET, endothelin), which cause vasoconstriction and increased afterload. This further reduces ejection fraction (EF) and CO, and the cycle repeats. The downward spiral is continued until a new steady state is reached in which CO is lower and afterload is higher tha ...
Nanobodies
Nanobodies

... can be excluded by spiking neutralising antibody or target receptor ...
Medication Administration
Medication Administration

... • Assemble the medications in the medication room. • Remove the meds from the drawer – Check for drug expiration date – Check for the five “rights” against the MAR **Check drawers at the beginning of your shift in case any medications are missing, you can order them from pharmacy. NEVER “borrow” med ...
Medication Administration
Medication Administration

... • Assemble the medications in the medication room. • Remove the meds from the drawer – Check for drug expiration date – Check for the five “rights” against the MAR **Check drawers at the beginning of your shift in case any medications are missing, you can order them from pharmacy. NEVER “borrow” med ...
From blood–brain barrier to blood–brain interface: new
From blood–brain barrier to blood–brain interface: new

... expanded our understanding of how the BBB functions, how it interacts with its environment, how it can be affected by disease, and how it can predispose to or even cause disease. Some of the work has come from an expansion of traditional areas of BBB research, but much more comes from integration wi ...
Product Information - Therapeutic Goods Administration
Product Information - Therapeutic Goods Administration

vemURAFenib - Cancer Care Ontario
vemURAFenib - Cancer Care Ontario

... Renal effects have been observed, ranging from mild/moderate creatinine increases to acute interstitial nephritis and acute tubular necrosis. Most creatinine increases appeared to be reversible; Pancreatitis has been reported rarely, usually within two weeks of starting treatment. Unexplained abdomi ...
Fixed Dose Combinations & Rational Pharmacotherapeutics DR
Fixed Dose Combinations & Rational Pharmacotherapeutics DR

... For any given infection, one of the above components is useless and adds to cost & ADR. Since amount of each drug is halved, efficacy is ↓ and chances of selective resistant strains is ↑ ...
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Neuropharmacology

Neuropharmacology is the study of how drugs affect cellular function in the nervous system, and the neural mechanisms through which they influence behavior. There are two main branches of neuropharmacology: behavioral and molecular. Behavioral neuropharmacology focuses on the study of how drugs affect human behavior (neuropsychopharmacology), including the study of how drug dependence and addiction affect the human brain. Molecular neuropharmacology involves the study of neurons and their neurochemical interactions, with the overall goal of developing drugs that have beneficial effects on neurological function. Both of these fields are closely connected, since both are concerned with the interactions of neurotransmitters, neuropeptides, neurohormones, neuromodulators, enzymes, second messengers, co-transporters, ion channels, and receptor proteins in the central and peripheral nervous systems. Studying these interactions, researchers are developing drugs to treat many different neurological disorders, including pain, neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease, psychological disorders, addiction, and many others.
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