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Drugs for Parasitic Infections (2013 Edition)
Drugs for Parasitic Infections (2013 Edition)

... Clindamycin plus quinine is also the treatment of choice for infections caused by B. duncani, B. divergens-like organisms or B. venatorum. Exchange tranfusion should be considered for severely ill patients and those with high (>10%) parasitemia or pulmonary, renal or hepatic compromise when infectio ...
Herbal Medication Pitfalls Question “Natural Product” or Drug
Herbal Medication Pitfalls Question “Natural Product” or Drug

... medicines available. However, one must be aware of the power of herbs to heal and, if misused, to cause imbalance. Herbs produce no side effects when used in the amounts required to effect a cure. Negative effects occur only when one fails to observe the cautions that herbalists have recognized afte ...
t.5
t.5

... GIT absorption of orally administered TCA is almost complete but since the drug passes through the liver & suffers from first-pass metabolism (FPM); the (F) is decreased to 50% in most patients. For that (F) range is broad & difficult to estimate in any individual patient. Rate of absorption is v ...
ANTINOCICEPTIVE ACTIVITY OF FREEZE DRIED POWDERED MORINDA CITRIFOLIA L. FRUIT
ANTINOCICEPTIVE ACTIVITY OF FREEZE DRIED POWDERED MORINDA CITRIFOLIA L. FRUIT

... to minutes [7]. It involves the localized reaction inside the body against the injurious agent caused by release of mediators such as prostaglandins, leukotrines, bradykinin, histamine, interleukin etc. from the tissue to kill those irritant substances [8]. NSAID’S and opiates are the drugs most wid ...
APPLICATIONS OF METABOLOMICS
APPLICATIONS OF METABOLOMICS

... a biological perturbation. The term 'metabonomics' is rarely used to describe research not directly related to human disease or nutrition. In practice, within the field of human disease research there is still a large degree of overlap in the way both terms are used, and they are often in effect syn ...
http://www.utdallas.edu/~tres/papers/moyer.etal.92.pdf
http://www.utdallas.edu/~tres/papers/moyer.etal.92.pdf

... from rise threshold to recrossing of the resting potential. Antidromic activation from the alveus or fimbria/fornix region was attempted in most cells and was successful in >90% of the cells. Cells were included in the study if they exhibited little spontaneous activity at rest, had an action-potent ...
Drug-Induced Cardiomyopathies
Drug-Induced Cardiomyopathies

... drugs and medications. Indeed, the cardiac muscle is widely known as a target of injury for many drugs and many other chemical compounds. Following their cardiotoxic action, these could be divided into two relevant categories: i) drugs and cardiotoxic substances leading to heart failure in terms of ...
Full Text  - The Journal of International Advanced Otology
Full Text - The Journal of International Advanced Otology

... respectively, with no dose-dependent effect.[7] When its pharmacological effects were evaluated in terms of lowering the heart rate and mean arterial pressure, it was considered as a good candidate to be used for controlled hypotension. However, limited amount of studies were performed in different ...
- Journal of Allergy and Clinical Immunology
- Journal of Allergy and Clinical Immunology

... for most drug-induced cutaneous allergic reactions. More recently, the epidemiology of drug-induced anaphylaxis has been evaluated. In 1999, Laxenaire3 published the fourth French survey of anaphylaxis during general anesthesia. Members of the Perioperative Anaphylactoid Reactions Study Group identi ...
Stimulants:
Stimulants:

... Voucher-based incentives for cocaine-free urine tests added to CRA Use of Incentives improved CRA outcomes further (Higgins et al, 1994) * 75% vs 40% completed 24 weeks of tx * 12 vs 6 weeks continuous cocaine abstinence ...
NHS Fife Guidelines for Benzodiazepine Prescribing in Benzodiazepine Dependence
NHS Fife Guidelines for Benzodiazepine Prescribing in Benzodiazepine Dependence

... insomnia and their widespread use from the 1970s onwards it has been recognised that long term use can result in physical and psychological dependence as well as tolerance to their use. In addition to patients prescribed benzodiazepines the illicit use, particularly by opioid drug users is a major p ...
Psychedelic Experiential Pharmacology
Psychedelic Experiential Pharmacology

effects of cytochrome p450 enzyme inhibitors on the
effects of cytochrome p450 enzyme inhibitors on the

... The desirable and undesirable effects of a drug are usually related to its concentration at the sites of action, which in turn depends on the amount of a drug administered, and on the pharmacokinetic behavior of a drug. Pharmacokinetics refers to the movement of drug into, through, and out of the bo ...
8. Anti-diabetics
8. Anti-diabetics

... 4) Disulfiram*-like reaction with alcohol (Chlorpropamide) “contain sulfur” Disulfiram R: Ingestion of chlorpropamide with alcohol  hyperemic flush 5) Weight gain alcoholism * Disulfiram is a drug used to support the treatment of chronic alcoholism by producing an acute sensitivity to alcohol. ...
Determination of levetiracetam in human plasma with minimal sample pretreatment Jens Martens-Lobenhoffer
Determination of levetiracetam in human plasma with minimal sample pretreatment Jens Martens-Lobenhoffer

... their respective main metabolites were tested for co-elution. Under the described conditions, none of the drugs or their metabolites are interfering with levetiracetam. 3.3. Validation The calibration is carried out using a standard solution of levetiracetam obtained from a “Keppra” 250 mg tablet. T ...
prescribing information
prescribing information

... and the Tmax occurs approximately 4 hours later from TREXIMET than from ANAPROX® DS (naproxen sodium tablets) 550 mg. AUC values for sumatriptan and for naproxen are similar for TREXIMET compared to IMITREX or ANAPROX DS, respectively. In a crossover study in 16 patients, the pharmacokinetics of bot ...
Metabolic Syndrome
Metabolic Syndrome

... • LV dysfunction (along with new  blocker) • Previous MI (along with new  blocker) ...
REMERON  PRODUCT MONOGRAPH
REMERON PRODUCT MONOGRAPH

... placebo-treated patients. REMERON® may cause mental or motor impairment because of this prominent sedative effect. Thus, patients should be cautioned about engaging in hazardous activities, such as driving a car or operating dangerous machines, until they are reasonably certain that REMERON® therapy ...
A Common Anticonvulsant Binding Site for Phenytoin
A Common Anticonvulsant Binding Site for Phenytoin

... The shift of inactivation curve predicted by eq. 3 is obviously different from that predicted by eq. 4. One may use saturating concentrations of the drugs to make the difference large and easily discernible. Fig. 3, A–C, shows the shift of inactivation curve (DV) in high concentrations of CBZ and LT ...
Diabetic Hypertension targetted Rx. by Dr. Sarma
Diabetic Hypertension targetted Rx. by Dr. Sarma

... • LV dysfunction (along with new  blocker) • Previous MI (along with new  blocker) ...
Drug - University of Washington
Drug - University of Washington

... Absorption: absorbed from GI and rapidly hydrolyzed in intestinal mucosa and blood, take with food Distribution: widely distributed to most tissues and fluids including CSF (not used for meningitis, though) Metabolism: metabolized to free cefuroxime plus acetaldehyde and acetic acid Excretion: prima ...
2014 - Atiner
2014 - Atiner

... Sciences, 5-8 May 2014, organized by the Health Research Unit of the Athens Institute for Education and Research. In total there were 33 papers, coming from 15 different countries (Austria, Brazil, Canada, China, Denmark, Egypt, India, Kingdom of Bahrain, Malaysia, Portugal, Saudi Arabia, Singapore, ...
LDL-C
LDL-C

... – Gemfibrozil may impair glucuronidation of statins (with cerivastatin being more susceptible than other statins such as simvastatin and atorvastatin) – Fenofibrate appears to have less potential for impairment of statin metabolism, and thus this may account for the reduced reports of fenofibrate pl ...
xtram plus
xtram plus

... Convulsions have been reported in tramadol-treated patients susceptible to seizures or taking other medications that lower the seizure threshold, especially selective serotonin re-uptake inhibitors, tricyclic antidepressants, antipsychotics, centrally acting analgesics or local anaesthesia. Epilepti ...
Management of behavioral problems in Alzheimer`s disease
Management of behavioral problems in Alzheimer`s disease

... Primary Dementia Collaborative Research Centre, School of Psychiatry, University of New South Wales, Sydney, Australia ...
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Neuropharmacology

Neuropharmacology is the study of how drugs affect cellular function in the nervous system, and the neural mechanisms through which they influence behavior. There are two main branches of neuropharmacology: behavioral and molecular. Behavioral neuropharmacology focuses on the study of how drugs affect human behavior (neuropsychopharmacology), including the study of how drug dependence and addiction affect the human brain. Molecular neuropharmacology involves the study of neurons and their neurochemical interactions, with the overall goal of developing drugs that have beneficial effects on neurological function. Both of these fields are closely connected, since both are concerned with the interactions of neurotransmitters, neuropeptides, neurohormones, neuromodulators, enzymes, second messengers, co-transporters, ion channels, and receptor proteins in the central and peripheral nervous systems. Studying these interactions, researchers are developing drugs to treat many different neurological disorders, including pain, neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease, psychological disorders, addiction, and many others.
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