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SOLID LIPID NANOPARTICLES: A REVIEW
SOLID LIPID NANOPARTICLES: A REVIEW

... tradition colloidal carriers such as - emulsions, liposomes and polymeric micro – and nanoparticles1. Nanoparticles made from solid lipids are attracting major attention as novel colloidal drug carrier for intravenous applications as they have been proposed as an alternative particulate carrier syst ...
Antimicrobial tissue concentrations. Infect Dis Clin N Am 17
Antimicrobial tissue concentrations. Infect Dis Clin N Am 17

... Plasma concentrations versus tissue concentrations Previously, because of the limited sampling techniques, plasma concentrations were monitored routinely and used as a surrogate marker for pharmacologic effect in most PK studies and clinical practice. With several recent breakthroughs in tissue sampl ...
alternative health practices in addiction treatment
alternative health practices in addiction treatment

... individual (or even the whole community) rather than on a disease entity. For example, in traditional Chinese medicine (TCM), different individuals addicted to alcohol may be "diagnosed" with a number of different patterns of disharmony, such as "damp heat condition of the liver" or "kidney yin hear ...
Synergistic Interaction between Fentanyl and
Synergistic Interaction between Fentanyl and

... Background: Lipophilic opioids and local anesthetics are often given intrathecally in combination for labor analgesia. However, the nature of the pharmacologic interaction between these drugs has not been clearly elucidated in humans. Methods: Three hundred nulliparous women randomly received 1 of 3 ...
D F PHARMACOKINETICS AND INTRODUCTION
D F PHARMACOKINETICS AND INTRODUCTION

... chemical designation is N-amidino-2(2,6-dichlorophenyl) acetamide monohydrochloride. The molecular formula is C9H9Cl2N3O • HCl, and the molecular weight is 282.55. The drug’s chemical structure is shown in Figure 1. This selective alpha2A-adrenergic receptor agonist is not a central nervous system ( ...
REFERENCE GUIDE FOR THE PHARMACY
REFERENCE GUIDE FOR THE PHARMACY

... specifically written for the preparation of NAPLEX® and Canadian Qualifying Exams. It contains over 1200 questions with answers and complete explanations. The exam puts more stress on trade names of drugs and therefore most questions have been formatted by using trade names instead of generic names. ...
Low Molecular Weight Heparins : Basic and Applied Considerations
Low Molecular Weight Heparins : Basic and Applied Considerations

... demonstrates that enoxaparin releases less vWF in comparison to dalteparin or UFH, resulting in reduced platelet aggregation. Thus, each of the LMWHs produces somewhat different effects in terms of their effects on vascular function. The release of such substances has an impact on the overall effect ...
Roger`s Phat Pharm Notes II
Roger`s Phat Pharm Notes II

... factors VII, IX, and X) of the intrinsic and extrinsic systems and of protein C. Actual mechanism is to block regeneration of KH2 (active hydroquinone form of Vit K) by an epoxide reductase. Delayed onset of action depending on drug pharmK and t1/2 of the 4 Vit K dep clotting factors, which must be ...
okf"kZd izfrosnu@Annual Report 2014-15
okf"kZd izfrosnu@Annual Report 2014-15

... I am happy to present to you the activities of NIPER, S.A.S. Nagar, and highlight our performance over the past year, in the form of Annual Report 2014-15. As an acknowledged brand name in the pharmaceutical sciences education and research sector in the country, the responsibilities of the Institute ...
Analysis of acquired resistance to metronomic oral
Analysis of acquired resistance to metronomic oral

... therapy in a preclinical model of advanced intraperitoneal ovarian cancer metastasis Previous studies by us and independently by Merritt et al. demonstrated the potent preclinical efficacy of concomitant combination of metronomic topotecan chemotherapy plus pazopanib for the treatment of advanced ov ...
Alternative antimicrobial drug(s) for treating penicillin
Alternative antimicrobial drug(s) for treating penicillin

... Antihypertensive drugs belonging to the same class: A. doxazosin (Cardura), prazosin (Minipress), metoprolol (Lopressor) B. nifedipine (Procardia, Adalat), verapamil (Isoptin, Calan), diltiazem (Cardiazem) C. clonidine (Catapres), guanabenz (Wytensin),terazosin (Hytrin) D. lisinopril (Prinvivil, Zes ...
NOTHAPODYTES NIMMONIANA STEM Research Article
NOTHAPODYTES NIMMONIANA STEM Research Article

... that produce a definite physiological action on the human body3. Plant based drugs provide outstanding contribution to modern therapeutics; for example Vinblastine isolated from the Catharanthus rosesus4 is used for the treatment of Hodgkins, nonHodgkins lymphomas, leukemia in children, testicular a ...
NMS vs EPSE vs SS vs MH Fact Sheet - Improving
NMS vs EPSE vs SS vs MH Fact Sheet - Improving

... Epidemiology ...
Antibiotics
Antibiotics

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Non-steroidal anti- inflammatory drugs (NSAIDs)
Non-steroidal anti- inflammatory drugs (NSAIDs)

... normal conjugating enzymes, causing the drug to be converted by mixed function oxidases to N-acetyl-p-benzoquinone imine. If not inactivated by conjugation with glutathione, this compound reacts with cell proteins and kills the cell. • Agents that increase glutathione (intravenous acetylcysteine or ...
Dangers of Statin Drugs
Dangers of Statin Drugs

... Dolichols also play a role of immense importance. In the cells they direct various proteins manufactured in response to DNA directives to their proper targets, ensuring that the cells respond correctly to genetically programmed instruction. Thus statin drugs can lead to unpredictable chaos on the ce ...
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... effectively inhibit the growth of B. gibsoni in vitro. Previous studies demonstrated the growth inhibitory effect of different antibiotics including macrolide and lyncomycin against protozoa. These antibiotics probably exhibit inhibitory effects against the apicomplex protozoa by targeting the apico ...
It`s time to set the story straight
It`s time to set the story straight

... Data and messages around OTC analgesics continue to evolve, and, therefore, treatment paradigms must evolve as well. Take another look, and you may find that some communications are not telling the full story. When considering which OTC analgesic to recommend, it is important to periodically review ...
What Clinicians Need to Know - AIDS Education and Training Centers
What Clinicians Need to Know - AIDS Education and Training Centers

... behavior and the potential to introduce the virus into the body  Meth also allows more virus to get into the cell ...
cdph/oa/adap - Magellan Rx
cdph/oa/adap - Magellan Rx

... Management will request additional information (client and drug specific) before considering the authorization. Please call 1-800-424-5906 or check website for diagnosis or specific PA form at https://cdph.magellanrx.com. ...
Spiking Phineas Gage: A Neurocomputational Theory of Cognitive
Spiking Phineas Gage: A Neurocomputational Theory of Cognitive

... and the amygdala. The VMPFC receives input from sensory cortices, representing the behavioral options, and from limbic structures, most notably the amygdala, which processes somatic states. Through these interconnections between cognitive and emotional processes, the VMPFC records the signals that d ...
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... systolic blood pressure is either unchanged or increased. The latter reflects a concurrent increase in cardiac output due isoprenalins positive inotropic and chronotropic effects. A dose-dependent increase in heart rate is thus a clear element in isoprenalins effect profile. Isoprenaline reduces the ...
PRESCRIBING INFORMATION Entex LA Pseudoephedrine
PRESCRIBING INFORMATION Entex LA Pseudoephedrine

... ingested is considered dangerous or excessive, induce vomiting with ipecac syrup unless the patient is convulsing, comatose, or has lost the gag reflex, in which case perform gastric lavage using a large bore tube. If indicated, follow with activated charcoal and saline cathartic. Since the effects ...
Antihistamines - Consumer Health Choices
Antihistamines - Consumer Health Choices

... the older ones must be taken two or more times a day because their effect wears off more quickly. Even so, there’s been a long-standing debate about just how much better the newer drugs are and whether they’re worth the extra cost. There’s no easy answer. Most doctors advise their patients to use th ...
Stevens Johnson Syndrome
Stevens Johnson Syndrome

... (according to the reporter and coded by a standard system), the type of reactions (up to 4 per case), the drugs and biologics to which the patient was estimate the risks of SIS and TEN in association with all drugs. The study attempted to ascertain all cases of SIS and TEN occurring in specific expo ...
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Neuropharmacology

Neuropharmacology is the study of how drugs affect cellular function in the nervous system, and the neural mechanisms through which they influence behavior. There are two main branches of neuropharmacology: behavioral and molecular. Behavioral neuropharmacology focuses on the study of how drugs affect human behavior (neuropsychopharmacology), including the study of how drug dependence and addiction affect the human brain. Molecular neuropharmacology involves the study of neurons and their neurochemical interactions, with the overall goal of developing drugs that have beneficial effects on neurological function. Both of these fields are closely connected, since both are concerned with the interactions of neurotransmitters, neuropeptides, neurohormones, neuromodulators, enzymes, second messengers, co-transporters, ion channels, and receptor proteins in the central and peripheral nervous systems. Studying these interactions, researchers are developing drugs to treat many different neurological disorders, including pain, neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease, psychological disorders, addiction, and many others.
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