Hereditary Pick’s disease with the G272V tau mutation shows predominant three-repeat
... specific antibodies) should supplement standard (immuno)histochemistry results and western blotting. Hereditary Pick disease as a clinicopathological phenotype of FTDP-17 has been associated with the G272V mutation in the tau gene (Sanders, 1939; Schenk, 1959; Groen and Endtz, 1982; Heutink et al., ...
... specific antibodies) should supplement standard (immuno)histochemistry results and western blotting. Hereditary Pick disease as a clinicopathological phenotype of FTDP-17 has been associated with the G272V mutation in the tau gene (Sanders, 1939; Schenk, 1959; Groen and Endtz, 1982; Heutink et al., ...
Planarian shows decision-making behavior in response to multiple
... that headless planarian body fragments and planarians that had specifically lost neural activity following regeneration-dependent conditional gene knockdown (Readyknock) of synaptotagmin in the brain lost both chemotactic and thigmotactic behaviors, suggesting that neural activity in the brain is re ...
... that headless planarian body fragments and planarians that had specifically lost neural activity following regeneration-dependent conditional gene knockdown (Readyknock) of synaptotagmin in the brain lost both chemotactic and thigmotactic behaviors, suggesting that neural activity in the brain is re ...
Role of Ratings of Perceived Exertion during Self
... To fully understand the complex relationship between exertion, effort and pacing, an appreciation of how such perceptions are developed and regulated within the brain is necessary. Indeed, the development of perceptions, interpretation of language and sensations associated with effort and exertion d ...
... To fully understand the complex relationship between exertion, effort and pacing, an appreciation of how such perceptions are developed and regulated within the brain is necessary. Indeed, the development of perceptions, interpretation of language and sensations associated with effort and exertion d ...
Intrinsic laminar lattice connections in primate visual cortex
... HRP injections were made in the lateral convexity of striate cortex. Generally two injections (each estimated as 500-750 pn in diameter) were placed close together, sometimes merging into one large injection site (for instance, SM4 in Figure 1C-G, where the injection is estimated as 1.2 pm across). ...
... HRP injections were made in the lateral convexity of striate cortex. Generally two injections (each estimated as 500-750 pn in diameter) were placed close together, sometimes merging into one large injection site (for instance, SM4 in Figure 1C-G, where the injection is estimated as 1.2 pm across). ...
CCNBook/Neuron
... After developing an understanding of these basic neural information processing mechanisms in Part I of this book, we continue our journey in Part II by exploring many different aspects of human thought (cognition), including perception and attention, motor control and reinforcement learning, learnin ...
... After developing an understanding of these basic neural information processing mechanisms in Part I of this book, we continue our journey in Part II by exploring many different aspects of human thought (cognition), including perception and attention, motor control and reinforcement learning, learnin ...
A forward genetic screen with a thalamocortical emx2
... the Emx2 gene, and discovered that some TCAs extend to the olfactory bulbs in this mutant. Mapping data suggest that other lines carry mutations in genes not previously known for roles in thalamocortical development. Conclusions: These data demonstrate the feasibility of a forward genetic approach t ...
... the Emx2 gene, and discovered that some TCAs extend to the olfactory bulbs in this mutant. Mapping data suggest that other lines carry mutations in genes not previously known for roles in thalamocortical development. Conclusions: These data demonstrate the feasibility of a forward genetic approach t ...
Midbrain fMRI: Applications, Limitations and Challenges
... Although the LC is a comparatively smaller structure than the SN/VTA, the regional specificity of its innervations is likely less than dopamine neurons. That said, norad renergic input to certain brain regions can be surprisingly selective in primates: in the visual cortex for instance, there is ...
... Although the LC is a comparatively smaller structure than the SN/VTA, the regional specificity of its innervations is likely less than dopamine neurons. That said, norad renergic input to certain brain regions can be surprisingly selective in primates: in the visual cortex for instance, there is ...
Dopamine in Schizophrenia
... dysfunction of cortical areas in schizophrenia. Thus, findings revealed a functional abnormality of the frontal cortex in schizophrenia (“hypofrontality”, e.g., Wolkin et al. 1985, 1988, 1992; Gur et al. 1987; Volkow et al. 1987; Weinberger 1988; Weinberger et al. 1988; Berman and Weinberger 1990; B ...
... dysfunction of cortical areas in schizophrenia. Thus, findings revealed a functional abnormality of the frontal cortex in schizophrenia (“hypofrontality”, e.g., Wolkin et al. 1985, 1988, 1992; Gur et al. 1987; Volkow et al. 1987; Weinberger 1988; Weinberger et al. 1988; Berman and Weinberger 1990; B ...
What and Where Information in the Caudate Tail Guides Saccades
... After 700 ms, a fractal target (TG) was pre- electrode tracks are superimposed, together with the borders of the cerebrum, cerebellum, and brainstem. The anterior commissure is sented, but the monkey was required to keep indicated by a green dot. The anterior part of the caudate includes the nucleus ...
... After 700 ms, a fractal target (TG) was pre- electrode tracks are superimposed, together with the borders of the cerebrum, cerebellum, and brainstem. The anterior commissure is sented, but the monkey was required to keep indicated by a green dot. The anterior part of the caudate includes the nucleus ...
THE VISUAL CLAUSTRUM OF THE CAT I. Structure and Connections`
... near the anterolateral edge of the LGN. Any mismatch between the stereotaxic coordinates of this recording site and those of the equivalent site in a standard projection of the visual field onto the LGN (Fig. 8 of Sanderson, 1971) was noted. Then the center of the visual claustrum was reached in a t ...
... near the anterolateral edge of the LGN. Any mismatch between the stereotaxic coordinates of this recording site and those of the equivalent site in a standard projection of the visual field onto the LGN (Fig. 8 of Sanderson, 1971) was noted. Then the center of the visual claustrum was reached in a t ...
Central Nervous System (CNS) The Brain Embryonic Development
... • Central core of the forebrain • Consists of three paired structures – thalamus, hypothalamus, and epithalamus • Encloses the third ventricle ...
... • Central core of the forebrain • Consists of three paired structures – thalamus, hypothalamus, and epithalamus • Encloses the third ventricle ...
Comparing the Functional Representations of Central and Border
... Because research has been focused mainly on whiskers whose barrels are located centrally within the PMBSF (central whiskers), it is unclear whether a whisker with a barrel at the border of the PMBSF (border whisker) also has a large functional representation. Although whisker responses have been rec ...
... Because research has been focused mainly on whiskers whose barrels are located centrally within the PMBSF (central whiskers), it is unclear whether a whisker with a barrel at the border of the PMBSF (border whisker) also has a large functional representation. Although whisker responses have been rec ...
Histamine neurons in the tuberomamillary nucleus: a whole center
... measurement of c-fos immunocytochemistry, a marker of cell activation, in histamine neurons identified with in situ hybridization of HDC mRNA. Under stress-free, basal conditions c-fos expression was detected in a negligible number of histamine neurons (less than 1%) distributed uniformly in the TMN ...
... measurement of c-fos immunocytochemistry, a marker of cell activation, in histamine neurons identified with in situ hybridization of HDC mRNA. Under stress-free, basal conditions c-fos expression was detected in a negligible number of histamine neurons (less than 1%) distributed uniformly in the TMN ...
Resting-State Functional Connectivity in Autism Spectrum
... males could be explained by this shift along the empathizing– systemizing continuum. Ozonoff and colleagues have proposed the executive dysfunction hypothesis, which suggests that deficits observed in ASDs are the result of poor executive function including working memory, inhibition, mental flexib ...
... males could be explained by this shift along the empathizing– systemizing continuum. Ozonoff and colleagues have proposed the executive dysfunction hypothesis, which suggests that deficits observed in ASDs are the result of poor executive function including working memory, inhibition, mental flexib ...
22 The Anatomy and Physiology of the Motor System in Humans
... behaving primates (and, rarely, humans). Until the late 1970s, most human mental processes, including complex motor control, were not amenable to direct experimental analysis. Since that time, however, several different approaches have been developed to characterize the neural substrates of informat ...
... behaving primates (and, rarely, humans). Until the late 1970s, most human mental processes, including complex motor control, were not amenable to direct experimental analysis. Since that time, however, several different approaches have been developed to characterize the neural substrates of informat ...
Identity-specific coding of future rewards in the human orbitofrontal
... guiding adaptive behavior. To choose different types of rewards, such as food, shelter, and mates, it is essential that predictive signals contain specific information about the identity of those outcomes. Food rewards differ dramatically in their nutritional composition, and identity-specific cues ...
... guiding adaptive behavior. To choose different types of rewards, such as food, shelter, and mates, it is essential that predictive signals contain specific information about the identity of those outcomes. Food rewards differ dramatically in their nutritional composition, and identity-specific cues ...
Schema Theory
... of sense-data, schema theory posits an active and selective process of schema formation (cf. Piaget’s notion of assimilation) which in some sense constructs reality as much as it embodies it. More generally, cognitive psychology views schemas as cognitive structures built up in the course of interac ...
... of sense-data, schema theory posits an active and selective process of schema formation (cf. Piaget’s notion of assimilation) which in some sense constructs reality as much as it embodies it. More generally, cognitive psychology views schemas as cognitive structures built up in the course of interac ...
Methamphetamine Users in Sustained Abstinence
... NAA via proton spectroscopy. Examples include Alzheimer disease,32-34 seizure disorder,35 multiple sclerosis,29 human immunodeficiency virus-associated brain disease,36,37 alcoholism,38 brain tumors,39,40 brain infarction,41 and head trauma.42 The Cho signal is primarily generated by free choline, p ...
... NAA via proton spectroscopy. Examples include Alzheimer disease,32-34 seizure disorder,35 multiple sclerosis,29 human immunodeficiency virus-associated brain disease,36,37 alcoholism,38 brain tumors,39,40 brain infarction,41 and head trauma.42 The Cho signal is primarily generated by free choline, p ...
Cortical Parcellations of the Macaque Monkey
... 1991; Kaas 2005). The macaque monkey is the most intensively studied nonhuman primate, yet despite a century’s effort, an accurate, consensus cortical parcellation is lacking for most of macaque cortex. A primary reason is that differences between neighboring areas are often subtle when assessed by ...
... 1991; Kaas 2005). The macaque monkey is the most intensively studied nonhuman primate, yet despite a century’s effort, an accurate, consensus cortical parcellation is lacking for most of macaque cortex. A primary reason is that differences between neighboring areas are often subtle when assessed by ...
Functional Connectivity of the Secondary Somatosensory Cortex of
... monkeys (Jones et al., 1975, 1978; Friedman and Murray, 1986), cats (Jones and Powell, 1968; Manzoni et al., 1979; Burton and Kopf, 1984), tree shrews (Weller et al., 1987), squirrels (Krubitzer et al., 1986), mice (Carvell and Simons, 1987), and rats (Koralek et al., 1990; Li et al., 1990; Fabri an ...
... monkeys (Jones et al., 1975, 1978; Friedman and Murray, 1986), cats (Jones and Powell, 1968; Manzoni et al., 1979; Burton and Kopf, 1984), tree shrews (Weller et al., 1987), squirrels (Krubitzer et al., 1986), mice (Carvell and Simons, 1987), and rats (Koralek et al., 1990; Li et al., 1990; Fabri an ...
Synesthetic personification
... synesthesia in their own right (Amin et al. 2011; Simner and Holenstein 2007). Simner and Holenstein argued that its characteristics are in line with modern definitions of synesthesia. For example, Hubbard (2007) defines synesthesia as a condition in which stimulation of one sensory or cognitive str ...
... synesthesia in their own right (Amin et al. 2011; Simner and Holenstein 2007). Simner and Holenstein argued that its characteristics are in line with modern definitions of synesthesia. For example, Hubbard (2007) defines synesthesia as a condition in which stimulation of one sensory or cognitive str ...
ROLE OF EARLY ACOUSTIC EXPERIENCE IN DEVELOPMENT OF THE RAT by
... termination of the sensory restriction (Cynader, Berman, & Hein, 1976; Wiesel & Hubel, 1965). 1.2 Critical Periods in Development Most experience-dependent neocortical changes occur during specific temporal periods when the functional and structural properties of neurons are particularly susceptible ...
... termination of the sensory restriction (Cynader, Berman, & Hein, 1976; Wiesel & Hubel, 1965). 1.2 Critical Periods in Development Most experience-dependent neocortical changes occur during specific temporal periods when the functional and structural properties of neurons are particularly susceptible ...
BMC Neuroscience
... layer IV, in comparison with the area of termination. In the reverse direction, projection neurons originate predominantly in layers V-VI. This hypothesis has received support in the ipsilateral connections of prefrontal areas with each other [15], and with distant sensory and association areas [17- ...
... layer IV, in comparison with the area of termination. In the reverse direction, projection neurons originate predominantly in layers V-VI. This hypothesis has received support in the ipsilateral connections of prefrontal areas with each other [15], and with distant sensory and association areas [17- ...
Complex Motion Perception and its Deficits
... characteristics of complex motion detectors. I will also discuss he use of optic flow information for perceptual tasks underlying visually guided behaviours. The sensitivity of the human visual system to optic flow stimuli has been studied by psychophysical means. To investigate whether higher corti ...
... characteristics of complex motion detectors. I will also discuss he use of optic flow information for perceptual tasks underlying visually guided behaviours. The sensitivity of the human visual system to optic flow stimuli has been studied by psychophysical means. To investigate whether higher corti ...
fulltext
... pars compacta (SNc) and the subthalamic nucleus (STN) 3 (Figure 1). Together, these structures link most areas of the cerebral cortex with upper motor neurons in the primary motor and premotor cortex and brainstem. The neurons within this loop modulate their activity in anticipation of and during mo ...
... pars compacta (SNc) and the subthalamic nucleus (STN) 3 (Figure 1). Together, these structures link most areas of the cerebral cortex with upper motor neurons in the primary motor and premotor cortex and brainstem. The neurons within this loop modulate their activity in anticipation of and during mo ...
Neuroesthetics
Neuroesthetics (or neuroaesthetics) is a relatively recent sub-discipline of empirical aesthetics. Empirical aesthetics takes a scientific approach to the study of aesthetic perceptions of art and music. Neuroesthetics received its formal definition in 2002 as the scientific study of the neural bases for the contemplation and creation of a work of art. Neuroesthetics uses neuroscience to explain and understand the aesthetic experiences at the neurological level. The topic attracts scholars from many disciplines including neuroscientists, art historians, artists, and psychologists.