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Mediation and the Brain: The Neuropsychology of
Mediation and the Brain: The Neuropsychology of

... • The self protective system • The caring system • Brain chemistry • Lessons along the way c. Douglas E. Noll 2006 ...
ABSTRACT BOOK  CHAMPALIMAUD NEUROSCIENCE
ABSTRACT BOOK CHAMPALIMAUD NEUROSCIENCE

... environmental changes. This is achieved mainly by changes in the connectivity between individual nerve cells. Synapses can be modulated in their strength by a variety of different mechanisms. We have investigated a number of these mechanisms, ranging from homeostatic control of synaptic efficacy to ...
Organization of Visual Areas in Macaque and Human Cerebral
Organization of Visual Areas in Macaque and Human Cerebral

... visuotopic organization, with the vertical meridian represented along their common boundary, and with upper fields represented ventrally and lower fields dorsally in each area. In addition, both areas have a prominent internal modularity related to the processing streams described in other chapters ...
Parallel basal ganglia circuits for voluntary and
Parallel basal ganglia circuits for voluntary and

... everyday behaviours spontaneously (Laplane and Baulac, 1984; Caplan et al., 1990). Patients with Parkinson’s disease may be less motivated in achieving goals and may also show symptoms of depression (Pluck and Brown, 2002). These observations, as well as many others not described here, suggest that ...
Heterotopic Transcallosal Projections Are Present throughout the
Heterotopic Transcallosal Projections Are Present throughout the

... the organization of transcallosal connections in different functional regions of the mouse cortex including the primary motor and somatosensory cortices. Such a systematic analysis of inter-hemispheric connectivity is important as defects in those projections—either innate or due to injury—can lead ...
The columnar organization of the neocortex
The columnar organization of the neocortex

... The neuroepithelium of the cerebral vesicle consists, in its early stages, of a single line of columnar epithelial cells, each of which stretches over the short distance from the ependymal surface of the neural tube to the pia, attached by endfeet to both surfaces (Sidman and Rakic, 1973). The three ...
Cicc4e_02-FINAL_PPT
Cicc4e_02-FINAL_PPT

... What are the nervous system, neurons, and nerves, and how do they relate to one another? How do neurons use neurotransmitters to communicate with each other and with the body? How do the brain and spinal cord interact, and what are some misconceptions about the brain, and what is neuroplasticity? Ho ...
PET Imaging of Differential Cortical Activation to
PET Imaging of Differential Cortical Activation to

... These studies of language processing have identified sites in the left inferior frontal cortex and posterior temporal cortex, regions classically implicated as speech/language centers from postmortem studies with aphasic patients (Geschwind, 1979). Furthermore, by comparing brain activation patterns ...
C ontribution of the anterior cingulate cortex to laser
C ontribution of the anterior cingulate cortex to laser

... were trained to associate a tone (conditioned stimulus, CS) and short CO 2 laser pulsation (unconditioned stimulus, US). Monotonous tone (800 Hz, 0.6 s) was delivered through a loud-speaker as CS. CO 2 laser pulses (5 W at 50 or 100 ms in duration) applied to the hind paw was adopted as US. The CS–U ...
datos de los autores
datos de los autores

Memory Extinction, Learning Anew, and Learning the New
Memory Extinction, Learning Anew, and Learning the New

... formation and plasticity of neural circuits. However, direct evidence for a transneuronal transfer of BDNF and its relation to neuronal activity remains elusive. We simultaneously injected complementary DNAs of green fluorescent protein (GFP)–tagged BDNF and red fluorescence protein into the nucleus ...
skull - lms.manhattan.edu
skull - lms.manhattan.edu

... endothelial cells, which are packed very tightly in brain capillaries. This higher density restricts passage of substances from the bloodstream much more than endothelial cells in capillaries elsewhere in the body. Astrocyte cell projections called astrocytic feet (also known as "glial limitans") su ...
The Neurology of Music for Post-Traumatic-Stress
The Neurology of Music for Post-Traumatic-Stress

... is shown to create biological changes within the body (Van Der Kolk & Saporta, 1999, p. 199). Lawrence Kolb (1987) proposed the symptoms of PTSD are due to neuroanatomical and neuroendocrine changes caused by stress. Since Kolb’s proposal, there has been evidence to support “neurological and neuro-a ...
Nervous System I - Union County College
Nervous System I - Union County College

... The function of a neuron is to transmit information from one part of the body to another. • This is done in the form of electrical impulses. • An impulse arrives at the dendrite • When the impulse is strong enough, it depolarizes the membrane and the impulse is transmitted along the axon • When the ...
Full version (PDF file)
Full version (PDF file)

... 1997). Besides Ca2+-binding properties, CR also shows affinity for copper ion Cu2+ (Groves and Palczewska 2001), which upon binding to CR antagonizes Ca2+ binding to CR. The mammalian neuronal cytoplasmic concentration of CR was estimated to be in order of tens of micromoles (Hackney et al. 2005). A ...
Segmentation in the perception and memory of events
Segmentation in the perception and memory of events

... causal sequence is initiated. In the Event Indexing Model [13], new mental models are initiated when there is a change in space, time, protagonist, objects, goals or causes. When the changes identified by these models occur, readers have been found to read more slowly. This is consistent with the pr ...
Pictures of pain: their contribution to the
Pictures of pain: their contribution to the

... mirroring mechanisms in the forms of simulated embodiment and empathetic engagement that follow upon visual observation’, and ‘no form of esthetic appreciation . . . can be fully envisaged without considering mirror systems and their role in embodied and empathetic responses . . .’ (Gallese and Free ...
Proc. Natl. Acad. Sci. USA
Proc. Natl. Acad. Sci. USA

... Animals and Surgical Procedures. Two adult monkeys (Macaca fuscata) were used in accordance with the University of Tokyo Animal Care Committee. Surgery on the anterior commissure (AC) was carried out under aseptic conditions and anesthesia with sodium pentobarbital (25–30 mgykg). The right hemispher ...
What in the brain tells us that this is pain - HAL
What in the brain tells us that this is pain - HAL

Categories in the Brain - Rice University -
Categories in the Brain - Rice University -

... • Additional properties of columns and functional webs can be derived from Mountcastle’s treatment together with neurolinguistic findings – Method: “connecting the dots” • Hypothesis IV: (Coming Soon!) “[T]he effective unit of operation…is not the single neuron and its axon, but bundles or groups of ...
Models and Measurements of Functional Maps in V1
Models and Measurements of Functional Maps in V1

... How are scenes encoded in the visual system? We know from single-unit studies that individual neurons are preferentially sensitive to a small set of stimulus features and that neuronal sensitivity to these features varies across the cortical sheet within a visual area (Hubel and Wiesel 1962). Over t ...
Prefrontal Activation Deficits During Episodic Memory in
Prefrontal Activation Deficits During Episodic Memory in

... Conclusions—The finding of prominent prefrontal dysfunction suggests that cognitive control deficits strongly contribute to episodic memory impairment in schizophrenia. Memory rehabilitation approaches developed for patients with frontal lobe lesions and pharmacotherapy approaches designed to improv ...
Between-Task Competition and Cognitive Control in Task Switching
Between-Task Competition and Cognitive Control in Task Switching

... The primary data analysis focused on ROIs that showed significant task-selective activity during the localizer scans. To identify these regions for each subject, we modeled the blood oxygen level-dependent (BOLD) response in the localizer scans using a general linear model (GLM) with separate regres ...
Neurotransmission in the rat amygdala related to fear and anxiety
Neurotransmission in the rat amygdala related to fear and anxiety

... panic, as well as having general relevance to the study of learning and memory. However, it should be emphasized that restricting this review to fear conditioning does not mean that this is the only function of the amygdala. On the contrary, this complex structure is also involved critically in atte ...
Large-Scale Fluorescence Calcium-Imaging
Large-Scale Fluorescence Calcium-Imaging

... the dynamics of hundreds of cells concurrently, target specific neuron types for study based on their genetic identities or connectivity patterns, reliably track individual cells for many weeks in behaving animals, extract the signals of individual neurons nearly regardless of their activity rates, ...
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Aging brain

Age is a major risk factor for most common neurodegenerative diseases, including Mild cognitive impairment, Alzheimer's disease, cerebrovascular disease, Parkinson's disease and Lou Gehrig's disease. While much research has focused on diseases of aging, there are few informative studies on the molecular biology of the aging brain (usually spelled ageing brain in British English) in the absence of neurodegenerative disease or the neuropsychological profile of healthy older adults. However, research does suggest that the aging process is associated with several structural, chemical, and functional changes in the brain as well as a host of neurocognitive changes. Recent reports in model organisms suggest that as organisms age, there are distinct changes in the expression of genes at the single neuron level. This page is devoted to reviewing the changes associated with healthy aging.
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