Chapter 20. Proteins
... that leads to the most stable, "comfortable" structure for the protein. How a protein folds is largely dictated by the primary sequence of amino acids. Each amino acid in the sequence will associate with other amino acids to conserve the most energy. This structure is stabilized by hydrogen bonds, h ...
... that leads to the most stable, "comfortable" structure for the protein. How a protein folds is largely dictated by the primary sequence of amino acids. Each amino acid in the sequence will associate with other amino acids to conserve the most energy. This structure is stabilized by hydrogen bonds, h ...
A point mutation in the Ch3 domain of human IgG3... secretion without affecting antigen specificity
... McLean et al., 2000) and the methods for the introduction of such vectors into mammalian cells and for harvesting of antibodies from culture supernatants are well established. However, despite the power of this technology, the production of antibodies in this way can be problematic. The recombinant ...
... McLean et al., 2000) and the methods for the introduction of such vectors into mammalian cells and for harvesting of antibodies from culture supernatants are well established. However, despite the power of this technology, the production of antibodies in this way can be problematic. The recombinant ...
Whey Protein: A Functional Food
... (branched chain amino acids), has long been popular in the exercise industry as a muscle-building supplement. However, research suggests it may have far wider applications as a functional food in the management of conditions such as cancer, hepatitis B, HIV, cardiovascular disease, osteoporosis and ...
... (branched chain amino acids), has long been popular in the exercise industry as a muscle-building supplement. However, research suggests it may have far wider applications as a functional food in the management of conditions such as cancer, hepatitis B, HIV, cardiovascular disease, osteoporosis and ...
Characterisation of the Aspergillus niger dapB gene, which encodes
... (Fig. 3b). A five to sevenfold increase in DPP IV activity was measured in the cell-free extracts of the DapB transformants compared to the control strain. This increase is clearly significant and shows that increased dapB mRNA levels correlate with higher DPP IV activity. Measurements of DPP IV activ ...
... (Fig. 3b). A five to sevenfold increase in DPP IV activity was measured in the cell-free extracts of the DapB transformants compared to the control strain. This increase is clearly significant and shows that increased dapB mRNA levels correlate with higher DPP IV activity. Measurements of DPP IV activ ...
The following equations and constants may be useful:
... surfaces at low pH values (e.g. pH < 6). However, its adherence properties become progressively weaker as the pH is raised. ...
... surfaces at low pH values (e.g. pH < 6). However, its adherence properties become progressively weaker as the pH is raised. ...
The following equations and constants may be useful:
... surfaces at low pH values (e.g. pH < 6). However, its adherence properties become progressively weaker as the pH is raised. ...
... surfaces at low pH values (e.g. pH < 6). However, its adherence properties become progressively weaker as the pH is raised. ...
Relationship between Protein Synthesis and Secretion in Liver Cells
... The effect of rotenone, 2,4-dinitrophenol, fructose and glycerol on the release into the medium of lactate dehydrogenase and glutamate dehydrogenase, enzymes of the cytoplasm and mitochondria, respectively, was assayed. Enzyme activities were monitored in both total cell suspension and incubation me ...
... The effect of rotenone, 2,4-dinitrophenol, fructose and glycerol on the release into the medium of lactate dehydrogenase and glutamate dehydrogenase, enzymes of the cytoplasm and mitochondria, respectively, was assayed. Enzyme activities were monitored in both total cell suspension and incubation me ...
(EC 2.2.1.1) active in the Calvin cycle of spinach chloroplasts
... spinach. Functional identity of the encoded mature subunit was shown by an 8.6-fold increase of TKL activity upon induction of Escherichia coli cells that overexpress the spinach TKL subunit under the control of the bacteriophage T7 promoter. Chloroplast localization of the cloned enzyme is shown by ...
... spinach. Functional identity of the encoded mature subunit was shown by an 8.6-fold increase of TKL activity upon induction of Escherichia coli cells that overexpress the spinach TKL subunit under the control of the bacteriophage T7 promoter. Chloroplast localization of the cloned enzyme is shown by ...
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS)
... blood fluke that occurs in China. It is the cause of Schistosomiasis japonica, a disease that still remains a significant health problem especially in lake and marshland regions. Schistosomiasis is an infection caused mainly by three schistosome species; Schistosoma mansoni, Schistosoma japonicum an ...
... blood fluke that occurs in China. It is the cause of Schistosomiasis japonica, a disease that still remains a significant health problem especially in lake and marshland regions. Schistosomiasis is an infection caused mainly by three schistosome species; Schistosoma mansoni, Schistosoma japonicum an ...
Protein Posttranslational Modifications: The Chemistry of Proteome
... The second route to proteome expansion is the focus of this Review: covalent posttranslational modification (PTM) of proteins at one or more sites.[3] As the name implies, these are covalent modifications that occur after DNA has been transcribed into RNA and translated into proteins. The nascent or ...
... The second route to proteome expansion is the focus of this Review: covalent posttranslational modification (PTM) of proteins at one or more sites.[3] As the name implies, these are covalent modifications that occur after DNA has been transcribed into RNA and translated into proteins. The nascent or ...
Comparison of good-and bad-quality cork: application of high
... Cork is one of the most valuable non-wood forest products and plays an important role in Mediterranean economies. The production of high-quality cork is dependent on both genome and environment, posing constraints on the industry because an ever-growing amount of bad-quality cork (BQC) development h ...
... Cork is one of the most valuable non-wood forest products and plays an important role in Mediterranean economies. The production of high-quality cork is dependent on both genome and environment, posing constraints on the industry because an ever-growing amount of bad-quality cork (BQC) development h ...
C. Flow Chart
... conjecture has arisen at the local scale. The modeling of protein loops is often considered a mini protein folding problem. In fact, most loop structure prediction methods are based on this conjecture. Database search methods have been successful in the realm of loop structure prediction. They depen ...
... conjecture has arisen at the local scale. The modeling of protein loops is often considered a mini protein folding problem. In fact, most loop structure prediction methods are based on this conjecture. Database search methods have been successful in the realm of loop structure prediction. They depen ...
Gene Section Transcription 3) Atlas of Genetics and Cytogenetics
... domain (1-715 + 7 unique amino acids resulting from frameshift) and is sometimes used as a dominant negative though there is also evidence that it regulates distinct genes as well. ...
... domain (1-715 + 7 unique amino acids resulting from frameshift) and is sometimes used as a dominant negative though there is also evidence that it regulates distinct genes as well. ...
Nuclear mitotic apparatus protein (NuMA): spindle association
... Fig. 1. (A) Schematic representation of various NuMA polypeptides derived from SV/NuMA expression vectors. The numbering system refers to amino acid residues on various NuMA isoforms. The carboxy-terminal 391, 52 and 39 residues are distinct for the NuMA-l, NuMA-m and NuMA-s proteins, respectively. ...
... Fig. 1. (A) Schematic representation of various NuMA polypeptides derived from SV/NuMA expression vectors. The numbering system refers to amino acid residues on various NuMA isoforms. The carboxy-terminal 391, 52 and 39 residues are distinct for the NuMA-l, NuMA-m and NuMA-s proteins, respectively. ...
SUPPLEMENTAL DATA FOR DUPLICATED SACCHAROMYCES
... - G121D: Asp side chain is possibly too far to form a hydrogen bond to FMN. S3.3. Cellular localization There are conflicting reports for the location of PST2 and RFS1. In earlier studies, the green fluorescent protein (GFP)-fusion protein of PST2 localized to the cytoplasm in a punctuate pattern [5 ...
... - G121D: Asp side chain is possibly too far to form a hydrogen bond to FMN. S3.3. Cellular localization There are conflicting reports for the location of PST2 and RFS1. In earlier studies, the green fluorescent protein (GFP)-fusion protein of PST2 localized to the cytoplasm in a punctuate pattern [5 ...
R26 :: CAG GCaMP6f - The Jackson Laboratory
... The Jackson Laboratory (JAX) Mouse Repository distributes mouse lines with optogenetic and transient-sensing (calcium-, voltage-, glutamate-) technologies. Opsins are light-activated proteins that alter membrane potential in neurons, so that stimulation with light allows rapid control of neuronal ac ...
... The Jackson Laboratory (JAX) Mouse Repository distributes mouse lines with optogenetic and transient-sensing (calcium-, voltage-, glutamate-) technologies. Opsins are light-activated proteins that alter membrane potential in neurons, so that stimulation with light allows rapid control of neuronal ac ...
The Calcium-Binding Activity of a Vacuole
... A vacuole membrane-associated calcium-binding protein with an apparent mass of 45 kD was purified from celery (Apium graveolens). This protein, VCaB45, is enriched in highly vacuolate tissues and is located within the lumen of vacuoles. Antigenically related proteins are present in many dicotyledono ...
... A vacuole membrane-associated calcium-binding protein with an apparent mass of 45 kD was purified from celery (Apium graveolens). This protein, VCaB45, is enriched in highly vacuolate tissues and is located within the lumen of vacuoles. Antigenically related proteins are present in many dicotyledono ...
Research Applications Of Proteolytic Enzymes In Molecular Biology
... concentrations) can diffuse from the organic phase into the water until the equilibrium is reached; the enzyme-catalyzed synthesis is followed by the diffusion of the products back into the organic phase. The organic phase reduces the dielectric constant of the medium and thus the acidity of the car ...
... concentrations) can diffuse from the organic phase into the water until the equilibrium is reached; the enzyme-catalyzed synthesis is followed by the diffusion of the products back into the organic phase. The organic phase reduces the dielectric constant of the medium and thus the acidity of the car ...
a Disulfide Bridge DataBase for the predictive analysis of cysteine
... Nevertheless much work has been devoted to the prediction of disulfide bonds [4,1,5,6]. The main drawback of these approaches is that they rely on sets of proteins, called by extension databases which are not organized as genuine databases, but which are a list of PDB identifiers. Some other researc ...
... Nevertheless much work has been devoted to the prediction of disulfide bonds [4,1,5,6]. The main drawback of these approaches is that they rely on sets of proteins, called by extension databases which are not organized as genuine databases, but which are a list of PDB identifiers. Some other researc ...
Predicting protein folding rates from geometric contact and amino
... San Francisco). We have slightly modified this data set and have removed structures that contain large hetero groups, such as iron protoporphyrins, or irregular amino acids. We have also incorporated additional data from the literature. These proteins belong to different structural classes: 18 are a ...
... San Francisco). We have slightly modified this data set and have removed structures that contain large hetero groups, such as iron protoporphyrins, or irregular amino acids. We have also incorporated additional data from the literature. These proteins belong to different structural classes: 18 are a ...
Full Text - Genome Biology and Evolution
... In evolution of mammals, some of essential genes for placental development are known to be of retroviral origin, as syncytin-1 derived from an envelope (env) gene of an endogenous retrovirus (ERV) aids in the cell fusion of placenta in humans. Although the placenta serves the same function in all pl ...
... In evolution of mammals, some of essential genes for placental development are known to be of retroviral origin, as syncytin-1 derived from an envelope (env) gene of an endogenous retrovirus (ERV) aids in the cell fusion of placenta in humans. Although the placenta serves the same function in all pl ...
Protein thermal stability: insights from atomic displacement
... positions due to thermal motion and positional disorder. Analysis of B values, therefore, is likely to provide newer insights into protein dynamics, flexibility of amino acids and protein stability. Molecular dynamics studies have suggested that protein unfolding might be initiated at sites that are ...
... positions due to thermal motion and positional disorder. Analysis of B values, therefore, is likely to provide newer insights into protein dynamics, flexibility of amino acids and protein stability. Molecular dynamics studies have suggested that protein unfolding might be initiated at sites that are ...
B130_Immunohistochemical identification of PAPP-A in
... is notebly expressed in unstable atherosclerotic plaques. It was shown that dPAPP-A is produced by activated cells of the immune system in unstable plaques and is released into the extracellular matrix. Also it was suggested that dPAPP-A could be involved in weakening of the fibrous cap. However, th ...
... is notebly expressed in unstable atherosclerotic plaques. It was shown that dPAPP-A is produced by activated cells of the immune system in unstable plaques and is released into the extracellular matrix. Also it was suggested that dPAPP-A could be involved in weakening of the fibrous cap. However, th ...
