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Principles of Virology
Principles of Virology

... What is the advantage that capsid and or core proteins are noncovalently connected? Describe the two modes that enveloped virions use for entry into their host cells? How do non-enveloped viruses enter their host-cells? Simple virus capsids are found in two types of structural arrangements: helical ...
Biology Course Summary Department: Science Semester 1
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Endogenous retrovirus



Endogenous retroviruses (ERVs) are endogenous viral elements in the genome that closely resemble and can be derived from retroviruses. They are abundant in the genomes of jawed vertebrates, and they comprise up to 5–8% of the human genome (lower estimates of ~1%). ERVs are a subclass of a type of gene called a transposon, which can be packaged and moved within the genome to serve a vital role in gene expression and in regulation. Researchers have suggested that retroviruses evolved from a type of transposable gene called a retrotransposon, which includes ERVs; these genes can mutate and instead of moving to another location in the genome they can become exogenous or pathogenic. This means that all ERVs may not have originated as an insertion by a retrovirus but that some may have been the source for the genetic information in the retroviruses they resemble.
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