Gene Section NQO1 NAD(P)H dehydrogenase, quinone 1 Atlas of Genetics and Cytogenetics
... Certain compounds such as antitumor quinones, however, can be bioactivated by two electron reduction and in these cases NQO1 serves as an activating enzyme. Because of the high levels of NQO1 in certain tumors, this has led to an interest in designing compounds which can be efficiently bioactivated ...
... Certain compounds such as antitumor quinones, however, can be bioactivated by two electron reduction and in these cases NQO1 serves as an activating enzyme. Because of the high levels of NQO1 in certain tumors, this has led to an interest in designing compounds which can be efficiently bioactivated ...
Genomic structure, chromosomal localization, and conserved alternative splice forms of thrombopoietin
... human and pig. The homology is substantially greater in the amino terminal half of TPO (epo homologous domain). This domain is 8 1 % to 85% identical between any two species, whereas the carboxyl half is only 57% to 67% identical. A conserved dibasic amino acid motif that could represent a protease ...
... human and pig. The homology is substantially greater in the amino terminal half of TPO (epo homologous domain). This domain is 8 1 % to 85% identical between any two species, whereas the carboxyl half is only 57% to 67% identical. A conserved dibasic amino acid motif that could represent a protease ...
bioinformatics module ii - Tetrahymena Genome Database
... screen for the whole class to follow. I have found that demonstrating two sections at a time gives a good breaking point to not overwhelm them with information (i.e. Demo section I and II; section III and IV; section V and VI; section VII and VIII; and then section IX and X). Section I: Finding the ...
... screen for the whole class to follow. I have found that demonstrating two sections at a time gives a good breaking point to not overwhelm them with information (i.e. Demo section I and II; section III and IV; section V and VI; section VII and VIII; and then section IX and X). Section I: Finding the ...
Bioinformatics: Molecular Computational Tools (Module II)
... screen for the whole class to follow. I have found that demonstrating two sections at a time gives a good breaking point to not overwhelm them with information (i.e. Demo section I and II; section III and IV; section V and VI; section VII and VIII; and then section IX and X). Section I: Finding the ...
... screen for the whole class to follow. I have found that demonstrating two sections at a time gives a good breaking point to not overwhelm them with information (i.e. Demo section I and II; section III and IV; section V and VI; section VII and VIII; and then section IX and X). Section I: Finding the ...
Bacterial physiological adaptations to contrasting edaphic
... genes classified at the broadest level (level 1 subsystems classification). Despite similarities in the abundance ranked order of hierarchically classified genes, a number of notable differences between soils of different pH were immediately apparent for several relevant functional categories, such ...
... genes classified at the broadest level (level 1 subsystems classification). Despite similarities in the abundance ranked order of hierarchically classified genes, a number of notable differences between soils of different pH were immediately apparent for several relevant functional categories, such ...
Supplementary Text and Figures
... Biotechnological inventions shall also be patentable if they concern: biological material which is isolated from its natural ...
... Biotechnological inventions shall also be patentable if they concern: biological material which is isolated from its natural ...
PAIRWISE ALIGNMENT OF TWO NUCLEOTIDE OR AMINO
... 0.2 = substitioni to j = log10 { (observed ij mutation rate) / (expected rate) } The value 0.2 is log10 of the relative expectation value of the mutation. Therefore, the expectation value is 100.2 = 1.6. So, a PAM score of 2 indicates that (in related sequences) the mutation would be expected to occ ...
... 0.2 = substitioni to j = log10 { (observed ij mutation rate) / (expected rate) } The value 0.2 is log10 of the relative expectation value of the mutation. Therefore, the expectation value is 100.2 = 1.6. So, a PAM score of 2 indicates that (in related sequences) the mutation would be expected to occ ...
Characterization of Rice Anthranilate Synthase
... Anthranilate synthase (AS) is a key enzyme in the synthesis of tryptophan (Trp), indole-3-acetic acid, and indole alkaloids. Two genes, OASA1 and OASA2, encoding AS ␣-subunits were isolated from a monocotyledonous plant, rice (Oryza sativa cv Nipponbare), and were characterized. A phylogenetic tree ...
... Anthranilate synthase (AS) is a key enzyme in the synthesis of tryptophan (Trp), indole-3-acetic acid, and indole alkaloids. Two genes, OASA1 and OASA2, encoding AS ␣-subunits were isolated from a monocotyledonous plant, rice (Oryza sativa cv Nipponbare), and were characterized. A phylogenetic tree ...
Characterization of mutations induced by N-methyl-N´-nitro
... [6], and gnd [7], resulted in only partial desensitization of the enzymes, despite continual ...
... [6], and gnd [7], resulted in only partial desensitization of the enzymes, despite continual ...
tRNA Core Hypothesis for the Transition from the RNA World to the
... its fixation. The Hypothesis The most plausible scenario of the origin of life is based on RNA molecules that exhibited simple catalytic functions. The tRNA molecules diversified novel structural conformations by the generation of new strands, and they formed new mini-helixes with catalytic function ...
... its fixation. The Hypothesis The most plausible scenario of the origin of life is based on RNA molecules that exhibited simple catalytic functions. The tRNA molecules diversified novel structural conformations by the generation of new strands, and they formed new mini-helixes with catalytic function ...
Identification of surface proteins in Enterococcus - UiO
... primarily via N-terminal or lipid anchors. Another 67 are predicted to be secreted or non-covalently attached to the surface. There is only limited experimental data supporting these predicted locations [13]. Furthermore, despite their expected importance for bacterial behaviour and impact, the func ...
... primarily via N-terminal or lipid anchors. Another 67 are predicted to be secreted or non-covalently attached to the surface. There is only limited experimental data supporting these predicted locations [13]. Furthermore, despite their expected importance for bacterial behaviour and impact, the func ...
Zebra Finch Glucokinase Containing Two Homologous Halves Is an
... have been cut into two halves. N-half of the predicted Zebra finch GK can be found on the branch with other glucokinase. It is situated in the same clade with Gallus gallus and Anolis carolinensis glucokinase, while two later proteins show more similarity with each other than with N-half of Taeniopy ...
... have been cut into two halves. N-half of the predicted Zebra finch GK can be found on the branch with other glucokinase. It is situated in the same clade with Gallus gallus and Anolis carolinensis glucokinase, while two later proteins show more similarity with each other than with N-half of Taeniopy ...
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... myeloid cells. 5-‐LO converts AA to LTA4 in cooperation with 5-‐LO activating protein (FLAP). LTA4 is converted to LTB4, by LTA4-‐hydrolase (LTA4H) or to LTC4 by LTC4-‐synthase (LTC4S). LTs act on cell ...
... myeloid cells. 5-‐LO converts AA to LTA4 in cooperation with 5-‐LO activating protein (FLAP). LTA4 is converted to LTB4, by LTA4-‐hydrolase (LTA4H) or to LTC4 by LTC4-‐synthase (LTC4S). LTs act on cell ...
Conserved Tryptophan Residues within Putative Transmembrane
... The organic anion-transporting polypeptides (OATPs, gene symbol SLCO) are a family of transporters that mediate sodium-independent transport of a wide spectrum of structurally independent compounds (Hagenbuch and Gui, 2008). Because of their broad substrate specificity and distribution in several im ...
... The organic anion-transporting polypeptides (OATPs, gene symbol SLCO) are a family of transporters that mediate sodium-independent transport of a wide spectrum of structurally independent compounds (Hagenbuch and Gui, 2008). Because of their broad substrate specificity and distribution in several im ...
Molecular insights into mitochondrial transcription and its
... production of most of the cellular energy-carrying molecule adenosine triphosphate (ATP), through the process of oxidative phosphorylation. The mitochondrion contains its own genome, a small circular DNA molecule (mtDNA), encoding essential subunits of the oxidative phosphorylation system. Initiatio ...
... production of most of the cellular energy-carrying molecule adenosine triphosphate (ATP), through the process of oxidative phosphorylation. The mitochondrion contains its own genome, a small circular DNA molecule (mtDNA), encoding essential subunits of the oxidative phosphorylation system. Initiatio ...
Invited Chapter One
... a single sequence and the third contains three proteins. Even though they signal for a DPP/BMP subfamily member and they are clearly R-Smads, SMA-2 and SMA-3 are different enough from other R-Smads (and each other) that they each constitute a distinct subfamily. Interestingly, the threemember nemato ...
... a single sequence and the third contains three proteins. Even though they signal for a DPP/BMP subfamily member and they are clearly R-Smads, SMA-2 and SMA-3 are different enough from other R-Smads (and each other) that they each constitute a distinct subfamily. Interestingly, the threemember nemato ...
AVP AVPR1a
... Peromyscus [13,19], and the impact of coding variation in AVPR1a signaling activity appears to be minimal [13]. In New World monkeys (NWM), AVPR1a coding variation among four genera (Aotus, Pithecia, Callicebus, and Saimiri) confirms selective evolution of the N-terminus and G-protein binding region ...
... Peromyscus [13,19], and the impact of coding variation in AVPR1a signaling activity appears to be minimal [13]. In New World monkeys (NWM), AVPR1a coding variation among four genera (Aotus, Pithecia, Callicebus, and Saimiri) confirms selective evolution of the N-terminus and G-protein binding region ...
ppt - pedagogix
... It is thus likely that it results from a common ancestry between the aligned sequences. In such case, we can thus admit the hypothesis of homology. ...
... It is thus likely that it results from a common ancestry between the aligned sequences. In such case, we can thus admit the hypothesis of homology. ...
Gene expression profiling of mice with genetically modified muscle
... different GLUTs (glucose transporters) to mediate glucose entry into the cell, as well as different forms of hexokinase/glucokinase for the phosphorylation of glucose. There are two genes, GYS1 and GYS2, encoding glycogen synthase in both mouse and human genomes. To date, GYS2 is only known to be ex ...
... different GLUTs (glucose transporters) to mediate glucose entry into the cell, as well as different forms of hexokinase/glucokinase for the phosphorylation of glucose. There are two genes, GYS1 and GYS2, encoding glycogen synthase in both mouse and human genomes. To date, GYS2 is only known to be ex ...
PrionPPSatBlack
... Examples of questions that can be explored through structural analyses Some mutations have been associated with prion diseases. By mapping these onto structures, propose a hypothesis to explain this. Most of the variation seems to be in the Nterminal region. Is there homology to this region in othe ...
... Examples of questions that can be explored through structural analyses Some mutations have been associated with prion diseases. By mapping these onto structures, propose a hypothesis to explain this. Most of the variation seems to be in the Nterminal region. Is there homology to this region in othe ...
Synonymous codon usage patterns in different parasitic
... Most amino acids are encoded by multiple codons. In most cases, the synonymous codons are not used randomly in different genomes (Grantham et al., 1980; Lloyd and Sharp, 1992). Furthermore, the pattern of codon usage can vary considerably among organisms, and also among genes from the same genome. C ...
... Most amino acids are encoded by multiple codons. In most cases, the synonymous codons are not used randomly in different genomes (Grantham et al., 1980; Lloyd and Sharp, 1992). Furthermore, the pattern of codon usage can vary considerably among organisms, and also among genes from the same genome. C ...
Global Properties of the Metabolic Map of
... genes for imidazole glycerol phosphate synthase subunits HisH and HisF are located at centisome positions 45.053 and 45.081, respectively. An example of a nonneighboring gene pair for subunits for a heteromeric enzyme is the pair coding for ArgF and ArgI, subunits of ornithine carbamoyltransferase, ...
... genes for imidazole glycerol phosphate synthase subunits HisH and HisF are located at centisome positions 45.053 and 45.081, respectively. An example of a nonneighboring gene pair for subunits for a heteromeric enzyme is the pair coding for ArgF and ArgI, subunits of ornithine carbamoyltransferase, ...
Dynamics and genetic diversification of Escherichia coli
... generation descendent of the E. coli B strain, REL606, were established from a clonal ancestral culture. These were serially sub-cultured for 2,000 generations in a defined minimal glucose medium in strict aerobic and strict anaerobic environments, as well as in a treatment that fluctuated between t ...
... generation descendent of the E. coli B strain, REL606, were established from a clonal ancestral culture. These were serially sub-cultured for 2,000 generations in a defined minimal glucose medium in strict aerobic and strict anaerobic environments, as well as in a treatment that fluctuated between t ...
Peroxisome Proliferator-Activated Receptors (PPARs)
... induce the proliferation of peroxisomes in cells. (Dreyer et al., Cell 68:879; 1992) • PPARα, PPARß/δ, and PPARγ • PPARδ was identified in humans and appeared to be closely related to the PPARß identified in Xenopus (Schmidt et al. Mol Endo 6:1634; 1992) ...
... induce the proliferation of peroxisomes in cells. (Dreyer et al., Cell 68:879; 1992) • PPARα, PPARß/δ, and PPARγ • PPARδ was identified in humans and appeared to be closely related to the PPARß identified in Xenopus (Schmidt et al. Mol Endo 6:1634; 1992) ...
Integration of omics data with biochemical reaction
... Printing: Háskólaprent, Fálkagata 2, 107 Reykjavik Reykjavik, Iceland, June 2014 ...
... Printing: Háskólaprent, Fálkagata 2, 107 Reykjavik Reykjavik, Iceland, June 2014 ...
Endogenous retrovirus
Endogenous retroviruses (ERVs) are endogenous viral elements in the genome that closely resemble and can be derived from retroviruses. They are abundant in the genomes of jawed vertebrates, and they comprise up to 5–8% of the human genome (lower estimates of ~1%). ERVs are a subclass of a type of gene called a transposon, which can be packaged and moved within the genome to serve a vital role in gene expression and in regulation. Researchers have suggested that retroviruses evolved from a type of transposable gene called a retrotransposon, which includes ERVs; these genes can mutate and instead of moving to another location in the genome they can become exogenous or pathogenic. This means that all ERVs may not have originated as an insertion by a retrovirus but that some may have been the source for the genetic information in the retroviruses they resemble.